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The map label for this gene is gstB [H]

Identifier: 154247252

GI number: 154247252

Start: 3697382

End: 3698041

Strand: Direct

Name: gstB [H]

Synonym: Xaut_3324

Alternate gene names: 154247252

Gene position: 3697382-3698041 (Clockwise)

Preceding gene: 154247251

Following gene: 154247253

Centisome position: 69.64

GC content: 62.27

Gene sequence:

>660_bases
ATGGTCTTTCGCTTGTCAAAACAAGGCGAGGCTGGAGGCGCCAGGGACATGAAGCTTTACGATACAAGTCGCGCGCCGAA
TCCGCGCCGCGTCCGCATCTTCCTGGCGGAAAAGGGTATTTCCGTTCCCACAGTGCAGGTGGACCTCGGCAAGCTGGAGC
AGAAGTCGGACGACTTCACCCGCCTCAATCCGCGCCAGCGCGTGCCTGTGCTGGAGCTGGATGACGGCACCGTCATCTGC
GAAACCATTGCAATCTGTCGCTATTTCGAGGCGCTGCAGCCCGAGCCCAACCTGTTTGGCCTCACGCCGACGGAGCAGGG
GCTGGTGGAAATGTGGCAGCGGCGGGTGGAGCTGGACCTGCTTTATCCCATCATGATGGTGCTCCGACACCTCAATCCCG
GCATGGCCGCCATGGAGGTGCCGCAGGTGCCGGAATGGGGCGAGGCGAATAAGCCCAAGGTCTTGGCCGCACTCGACTTT
TTCAACGATGCCCTGGCCGGTCGCGACTATATCGCGGGCGACCGTTTCACCGTGGCGGACATTACGTTGTTGGTGGCTGT
GGATTTCATGCGGGTGATCCGCGTGGCACTCGCGCCCACCCATGAAAACCTTGCCCGCTGGCATGCGGCCGTCTCGGCCC
GGCCGAGCGCAAAGGCTTGA

Upstream 100 bases:

>100_bases
CGCCCATCCGCGCGGGTCCTGAGGGGCGTGGAGGGCTGCTGCCGCCGCATGACTTGGCTTTTTGCCACTGCGCCGGAGCC
CTTGCGTGGCCGGGACAGGC

Downstream 100 bases:

>100_bases
AATCATGAAGCTGAAGGTGGTCGGCTGCGGCGACGCGTTCGGCTCCGGCGGGCGCGGCAACAGCTGCTTCCTGGTGGCCT
CACAGGCGGTCAAGGCCACC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MVFRLSKQGEAGGARDMKLYDTSRAPNPRRVRIFLAEKGISVPTVQVDLGKLEQKSDDFTRLNPRQRVPVLELDDGTVIC
ETIAICRYFEALQPEPNLFGLTPTEQGLVEMWQRRVELDLLYPIMMVLRHLNPGMAAMEVPQVPEWGEANKPKVLAALDF
FNDALAGRDYIAGDRFTVADITLLVAVDFMRVIRVALAPTHENLARWHAAVSARPSAKA

Sequences:

>Translated_219_residues
MVFRLSKQGEAGGARDMKLYDTSRAPNPRRVRIFLAEKGISVPTVQVDLGKLEQKSDDFTRLNPRQRVPVLELDDGTVIC
ETIAICRYFEALQPEPNLFGLTPTEQGLVEMWQRRVELDLLYPIMMVLRHLNPGMAAMEVPQVPEWGEANKPKVLAALDF
FNDALAGRDYIAGDRFTVADITLLVAVDFMRVIRVALAPTHENLARWHAAVSARPSAKA
>Mature_219_residues
MVFRLSKQGEAGGARDMKLYDTSRAPNPRRVRIFLAEKGISVPTVQVDLGKLEQKSDDFTRLNPRQRVPVLELDDGTVIC
ETIAICRYFEALQPEPNLFGLTPTEQGLVEMWQRRVELDLLYPIMMVLRHLNPGMAAMEVPQVPEWGEANKPKVLAALDF
FNDALAGRDYIAGDRFTVADITLLVAVDFMRVIRVALAPTHENLARWHAAVSARPSAKA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=183, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322968, Length=207, Percent_Identity=40.5797101449275, Blast_Score=156, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571670, Length=165, Percent_Identity=32.1212121212121, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221378141, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI62472445, Length=186, Percent_Identity=28.494623655914, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221378983, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 24555; Mature: 24555

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFRLSKQGEAGGARDMKLYDTSRAPNPRRVRIFLAEKGISVPTVQVDLGKLEQKSDDFT
CEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHHHCCCCCCC
RLNPRQRVPVLELDDGTVICETIAICRYFEALQPEPNLFGLTPTEQGLVEMWQRRVELDL
CCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHH
LYPIMMVLRHLNPGMAAMEVPQVPEWGEANKPKVLAALDFFNDALAGRDYIAGDRFTVAD
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHH
ITLLVAVDFMRVIRVALAPTHENLARWHAAVSARPSAKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVFRLSKQGEAGGARDMKLYDTSRAPNPRRVRIFLAEKGISVPTVQVDLGKLEQKSDDFT
CEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHHHCCCCCCC
RLNPRQRVPVLELDDGTVICETIAICRYFEALQPEPNLFGLTPTEQGLVEMWQRRVELDL
CCCHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHH
LYPIMMVLRHLNPGMAAMEVPQVPEWGEANKPKVLAALDFFNDALAGRDYIAGDRFTVAD
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHH
ITLLVAVDFMRVIRVALAPTHENLARWHAAVSARPSAKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]