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The map label for this gene is cobH

Identifier: 154247212

GI number: 154247212

Start: 3644195

End: 3644830

Strand: Reverse

Name: cobH

Synonym: Xaut_3284

Alternate gene names: 154247212

Gene position: 3644830-3644195 (Counterclockwise)

Preceding gene: 154247213

Following gene: 154247211

Centisome position: 68.65

GC content: 72.48

Gene sequence:

>636_bases
ATGACCCTCCCCTTCAACTACGTGCGCGACGGCACCGCCATCTACGAGCGCTCCTTCGCCATTATCCGCGCCGAGGCCGA
CCTGTCGCGCTTCTCCCCCGAGGAGGAAGACGTGGCGGTGCGCATGATCCACGCCTGCGGGCTGGTGGACGCGGCGCGCG
ATTTCGTCTTCGGCCCGGGCGTGGTGGCCGCCGCCCGCGCGGCACTGCAAGCCGGCGCGCCCATCCTGTGCGATGCCCAG
ATGGTGGCCCACGGCATCACCCGCGCCCGCCTGCCAGCCAGCAACGAGGTGGTCTGCACCCTGCGCGATCCCGCCGTGCC
GGCGCTGGCCGAAAAGCTCGGCACCACCCGCTCGGCCGCCGCGCTGGAATTGTGGCGCGAGCAGCTTGCCGGCGCGGTCG
TCGCCATCGGCAATGCGCCCACCGCCCTCTTCCATTTGCTGGAAATGCTAGACAAGGGCGCACCCCGCCCCGCCGCCATC
CTGGGCATGCCGGTGGGCTTCGTGGGCGCGGCGGAATCCAAGGATGCGCTGGCGGCCGATCCGCGCGGCGTGCCGTTCGC
CATCGTGCGCGGGCGGCTCGGCGGCAGCGCCATCACCTCGGCCGCCGTCAACGCGCTGGCGAGGGCCGGGCTATGA

Upstream 100 bases:

>100_bases
GGGCTTCTGGCCCGGATGCAAGAGGCAGGTTTACCGGCGGGCCTGTGGCTGCGCGAAGGAAACGACAGACCGATGGTGAA
GACGTGACGAGCCGCGCAGC

Downstream 100 bases:

>100_bases
AGGGCCAGCTCATCGGCGTGGGCGTCGGCCCCGGCGACCCCGATCTCATGACCCTCAAAGCGGTGAAGGCCATCGCCGGC
GCCGACGTGGTGGGCTATTT

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTLPFNYVRDGTAIYERSFAIIRAEADLSRFSPEEEDVAVRMIHACGLVDAARDFVFGPGVVAAARAALQAGAPILCDAQ
MVAHGITRARLPASNEVVCTLRDPAVPALAEKLGTTRSAAALELWREQLAGAVVAIGNAPTALFHLLEMLDKGAPRPAAI
LGMPVGFVGAAESKDALAADPRGVPFAIVRGRLGGSAITSAAVNALARAGL

Sequences:

>Translated_211_residues
MTLPFNYVRDGTAIYERSFAIIRAEADLSRFSPEEEDVAVRMIHACGLVDAARDFVFGPGVVAAARAALQAGAPILCDAQ
MVAHGITRARLPASNEVVCTLRDPAVPALAEKLGTTRSAAALELWREQLAGAVVAIGNAPTALFHLLEMLDKGAPRPAAI
LGMPVGFVGAAESKDALAADPRGVPFAIVRGRLGGSAITSAAVNALARAGL
>Mature_210_residues
TLPFNYVRDGTAIYERSFAIIRAEADLSRFSPEEEDVAVRMIHACGLVDAARDFVFGPGVVAAARAALQAGAPILCDAQM
VAHGITRARLPASNEVVCTLRDPAVPALAEKLGTTRSAAALELWREQLAGAVVAIGNAPTALFHLLEMLDKGAPRPAAIL
GMPVGFVGAAESKDALAADPRGVPFAIVRGRLGGSAITSAAVNALARAGL

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21822; Mature: 21691

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPFNYVRDGTAIYERSFAIIRAEADLSRFSPEEEDVAVRMIHACGLVDAARDFVFGPG
CCCCCHHHHCCHHHHHHCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VVAAARAALQAGAPILCDAQMVAHGITRARLPASNEVVCTLRDPAVPALAEKLGTTRSAA
HHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCHHHH
ALELWREQLAGAVVAIGNAPTALFHLLEMLDKGAPRPAAILGMPVGFVGAAESKDALAAD
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PRGVPFAIVRGRLGGSAITSAAVNALARAGL
CCCCCCEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLPFNYVRDGTAIYERSFAIIRAEADLSRFSPEEEDVAVRMIHACGLVDAARDFVFGPG
CCCCHHHHCCHHHHHHCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VVAAARAALQAGAPILCDAQMVAHGITRARLPASNEVVCTLRDPAVPALAEKLGTTRSAA
HHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHCCCHHHH
ALELWREQLAGAVVAIGNAPTALFHLLEMLDKGAPRPAAILGMPVGFVGAAESKDALAAD
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC
PRGVPFAIVRGRLGGSAITSAAVNALARAGL
CCCCCCEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]