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The map label for this gene is gcvT [H]

Identifier: 154247113

GI number: 154247113

Start: 3529805

End: 3532123

Strand: Reverse

Name: gcvT [H]

Synonym: Xaut_3184

Alternate gene names: 154247113

Gene position: 3532123-3529805 (Counterclockwise)

Preceding gene: 154247114

Following gene: 154247112

Centisome position: 66.53

GC content: 69.56

Gene sequence:

>2319_bases
ATGGACGCTTCCCTCCTCCCGCCCGGCCCGTCGCGCAGCGCGCCCGCCACCCGCCCCCGCGAATGCGTGGTGGTGCGCGG
CGGCGGTGTGGCCGCGATCGTGCTCGGTGCCGGCGACGCCATCGCGATCCGCGACGGCGAAGGGCTGCAGCCGGCCGTCG
TGTTCGCCATCGATGGCGAAGGGCGGGCGGACAGCACCGTGCTCGGCCTCGAAGGCCCGGCCGATGCGGGCCTCGCGGAG
GTGTTGGCTCTGGGGGGAGAGGGGAGCGCGCAGGTGGCGCATGCGCTGGCGGCGCGGGGGATCGCGCCGGCGGCCGTGAC
CGGGCACATAGTGCTCGCCGGCGGTCATTCGGCACAGACGCAGGTCGCGCTCACGGCGCGGCGCGAGGTTCTGGTGGTGG
TGGCGGCCCCCGGCGGCCCCATGGCGCCCGATGGGCAGGACGCGCCGACCGACATCGAAGTCACCGTCACCCGCGCCCCC
GGCAACGAACGCCCGCTGCCGGCGCCTTTGGCCGAGCCGAAGCTCGACCTCAGGGTCCCGGCTGCAGAGGCCCGCGCCTT
CCGGGTGAAGGCCGGTGACTATATCCAGATCATCGACGTGGACGGACGCCAGTGCTCGGATTTCCTCGCCTTCGACGCGG
CGGCGCTGGAGCAGGGCGCGGAATTCGGCCTCGACGCCACCACCACCCGCACCCTCATGGGCGCCGCCTATCCGGGGCCG
GGGCTGCACTCGAAATATTATGACGAGCGCCAGATCCCGCTGGTGGAGGTGATCCGCGACACGGTGGGCCGGCACGACAC
CTTCGCGCTCGCCTGCTCCGCCAAATATTACGAGGACATGGGCTATCCGGGTCACGCCAATTGCTCGGACAATTTCAACG
CGGTGCTTGCGCCCTACGGCATCCGCACGCGCGCCGGCTGGCCGGCCATCAACTTCTTCTACAATACCGCCGTGGACCAC
ACCAACGCGCTCACCATGGACGAGCCCTGGTCGCGGCCCGGCGACTATGTGCTGATGAAGGCGCTCACCGACCTCGTCTG
CGCCACCTCGTCCTGCGCCGACGACATCGACCCGGCCAACGGCTGGGTGCCCACCGACATCCATGTGCGCGTCTATGACG
GCGCCGAGAGCTTCTCCAAGGGGACCGCATTCCGCATGAATGCCGCAGCCGAGCCGCGCCTGACGCGCGAGAGCGCCTTT
CATCCGCGCCTGGCGCAGATGACCCGCAGCTTCGTGGAGTATCGCGGCTTCTGGCTGCCCACCTGCTTCACCGGCGAGGG
TCCCATCGCCGAATACTGGGCCTGCCGCGAGACCGCGGCGGTGATGGACCTCTCCCCTTTGCGCAAGTTCGAGGTGACCG
GGCCGGACGCCGAGCTGCTGCTCCAGCGCACGGTGACGCGCGACATGCGCAAGCTGGCGGTGGGACAGGTGGTCTATACC
GCGCTGACCTATGACCATGGCGGCATGATCGACGACGCCACCATCTTCCGCCTGGCCCCGGCCAATTTCCGGGTGGTGTG
CGGGGAGGAATTCACCGGCGCCTGGCTGCGCGACAAGGCGCGCGAATGGGGGCTGAATGCCTTCGTGCGCTCCTCCACCG
ACCAGTTGCACAATATTGCGGTGCAGGGGCCGCTCTCCCGCGAGATCCTCGCCGAGGTGATCTGGACCGGCCCGACGCAG
CCCGCCATTGCCGAGCTGAAATGGTTCCGTTTCGCCGTGGCCCGGCTCGGCGGCCCCATGGGGCCGGCGCTGGTGGTCTC
GCGCACCGGCTATACGGGGGAGCTCGGCTACGAGATCTGGTGCCACCCGAAGGATGCGGGCGCGGTCTTCGACGCCGTGT
GGGCGGCGGGTGTGCCGAAAGGCATGAAGCCGCTGGGCCTTGCCGCCCTCGACATGCTGCGCATCGAGGCGGGGCTGGTG
TTCGCCGGATATGATTTCTGCGACCAGACCGACCCGTTCGAGGCCGGCATCGGATTCGCAGTGGCGGAGAAGGAGGAGGA
TTTCGTGGGCAAGGCGGCGCTCATGCGGCGCAAGGCCAGTCCGGCCCGCAAGATGGTGGGCTTGAGGATCGAGGGCAATG
ACGCGGTCGGCCACGGCGACCCGCTCTACATGGGCCGCGCGCAGGTGGGTGTCGTCACCAGCGCCACCCATTCGCCCATC
CTGAAAGGCCAGATCGCGCTGGCGCGGATCGATGTCGCCCATGGGGCCACGGGCACGCAGGTGGAGATCGGCAAGCTGGA
CGGCCTGAAAAAACGCATCGGCGCCGAGATCGTGCCCTTCCCGCACTTCGACCCGCAGAAGACCCGGGTGCGTGCCTGA

Upstream 100 bases:

>100_bases
CACATGCACACCGACGGCGAGGGCGATCCTCTTCTTTATTACCGCGGCAGTTACCGGCTGCTCGCGAGCCTCATGCAAGA
CAGCTGAACCAGAGGGCTGA

Downstream 100 bases:

>100_bases
CGGGCGATGCACGGCGGCCGATCGAGCTTTCGGCCGCCAATGCCATGTATTGCTTTGAAGACCTCCAGACGACATTTCGT
CTGGAGGTATTTTCGCGTGC

Product: glycine cleavage T protein (aminomethyl transferase)

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MDASLLPPGPSRSAPATRPRECVVVRGGGVAAIVLGAGDAIAIRDGEGLQPAVVFAIDGEGRADSTVLGLEGPADAGLAE
VLALGGEGSAQVAHALAARGIAPAAVTGHIVLAGGHSAQTQVALTARREVLVVVAAPGGPMAPDGQDAPTDIEVTVTRAP
GNERPLPAPLAEPKLDLRVPAAEARAFRVKAGDYIQIIDVDGRQCSDFLAFDAAALEQGAEFGLDATTTRTLMGAAYPGP
GLHSKYYDERQIPLVEVIRDTVGRHDTFALACSAKYYEDMGYPGHANCSDNFNAVLAPYGIRTRAGWPAINFFYNTAVDH
TNALTMDEPWSRPGDYVLMKALTDLVCATSSCADDIDPANGWVPTDIHVRVYDGAESFSKGTAFRMNAAAEPRLTRESAF
HPRLAQMTRSFVEYRGFWLPTCFTGEGPIAEYWACRETAAVMDLSPLRKFEVTGPDAELLLQRTVTRDMRKLAVGQVVYT
ALTYDHGGMIDDATIFRLAPANFRVVCGEEFTGAWLRDKAREWGLNAFVRSSTDQLHNIAVQGPLSREILAEVIWTGPTQ
PAIAELKWFRFAVARLGGPMGPALVVSRTGYTGELGYEIWCHPKDAGAVFDAVWAAGVPKGMKPLGLAALDMLRIEAGLV
FAGYDFCDQTDPFEAGIGFAVAEKEEDFVGKAALMRRKASPARKMVGLRIEGNDAVGHGDPLYMGRAQVGVVTSATHSPI
LKGQIALARIDVAHGATGTQVEIGKLDGLKKRIGAEIVPFPHFDPQKTRVRA

Sequences:

>Translated_772_residues
MDASLLPPGPSRSAPATRPRECVVVRGGGVAAIVLGAGDAIAIRDGEGLQPAVVFAIDGEGRADSTVLGLEGPADAGLAE
VLALGGEGSAQVAHALAARGIAPAAVTGHIVLAGGHSAQTQVALTARREVLVVVAAPGGPMAPDGQDAPTDIEVTVTRAP
GNERPLPAPLAEPKLDLRVPAAEARAFRVKAGDYIQIIDVDGRQCSDFLAFDAAALEQGAEFGLDATTTRTLMGAAYPGP
GLHSKYYDERQIPLVEVIRDTVGRHDTFALACSAKYYEDMGYPGHANCSDNFNAVLAPYGIRTRAGWPAINFFYNTAVDH
TNALTMDEPWSRPGDYVLMKALTDLVCATSSCADDIDPANGWVPTDIHVRVYDGAESFSKGTAFRMNAAAEPRLTRESAF
HPRLAQMTRSFVEYRGFWLPTCFTGEGPIAEYWACRETAAVMDLSPLRKFEVTGPDAELLLQRTVTRDMRKLAVGQVVYT
ALTYDHGGMIDDATIFRLAPANFRVVCGEEFTGAWLRDKAREWGLNAFVRSSTDQLHNIAVQGPLSREILAEVIWTGPTQ
PAIAELKWFRFAVARLGGPMGPALVVSRTGYTGELGYEIWCHPKDAGAVFDAVWAAGVPKGMKPLGLAALDMLRIEAGLV
FAGYDFCDQTDPFEAGIGFAVAEKEEDFVGKAALMRRKASPARKMVGLRIEGNDAVGHGDPLYMGRAQVGVVTSATHSPI
LKGQIALARIDVAHGATGTQVEIGKLDGLKKRIGAEIVPFPHFDPQKTRVRA
>Mature_772_residues
MDASLLPPGPSRSAPATRPRECVVVRGGGVAAIVLGAGDAIAIRDGEGLQPAVVFAIDGEGRADSTVLGLEGPADAGLAE
VLALGGEGSAQVAHALAARGIAPAAVTGHIVLAGGHSAQTQVALTARREVLVVVAAPGGPMAPDGQDAPTDIEVTVTRAP
GNERPLPAPLAEPKLDLRVPAAEARAFRVKAGDYIQIIDVDGRQCSDFLAFDAAALEQGAEFGLDATTTRTLMGAAYPGP
GLHSKYYDERQIPLVEVIRDTVGRHDTFALACSAKYYEDMGYPGHANCSDNFNAVLAPYGIRTRAGWPAINFFYNTAVDH
TNALTMDEPWSRPGDYVLMKALTDLVCATSSCADDIDPANGWVPTDIHVRVYDGAESFSKGTAFRMNAAAEPRLTRESAF
HPRLAQMTRSFVEYRGFWLPTCFTGEGPIAEYWACRETAAVMDLSPLRKFEVTGPDAELLLQRTVTRDMRKLAVGQVVYT
ALTYDHGGMIDDATIFRLAPANFRVVCGEEFTGAWLRDKAREWGLNAFVRSSTDQLHNIAVQGPLSREILAEVIWTGPTQ
PAIAELKWFRFAVARLGGPMGPALVVSRTGYTGELGYEIWCHPKDAGAVFDAVWAAGVPKGMKPLGLAALDMLRIEAGLV
FAGYDFCDQTDPFEAGIGFAVAEKEEDFVGKAALMRRKASPARKMVGLRIEGNDAVGHGDPLYMGRAQVGVVTSATHSPI
LKGQIALARIDVAHGATGTQVEIGKLDGLKKRIGAEIVPFPHFDPQKTRVRA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=349, Percent_Identity=28.6532951289398, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI257796258, Length=344, Percent_Identity=29.3604651162791, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI44662838, Length=344, Percent_Identity=29.3604651162791, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI194306651, Length=323, Percent_Identity=26.625386996904, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI197927446, Length=367, Percent_Identity=28.0653950953678, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI21361378, Length=367, Percent_Identity=28.0653950953678, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI257796256, Length=302, Percent_Identity=30.794701986755, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI257796254, Length=232, Percent_Identity=31.8965517241379, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1789272, Length=337, Percent_Identity=30.8605341246291, Blast_Score=131, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560118, Length=372, Percent_Identity=27.9569892473118, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32563613, Length=347, Percent_Identity=27.9538904899135, Blast_Score=106, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71994045, Length=364, Percent_Identity=28.8461538461538, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994052, Length=336, Percent_Identity=29.1666666666667, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320222, Length=367, Percent_Identity=25.6130790190736, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI20129441, Length=389, Percent_Identity=28.5347043701799, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI20130091, Length=369, Percent_Identity=28.7262872628726, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571104, Length=314, Percent_Identity=25.796178343949, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 82368; Mature: 82368

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASLLPPGPSRSAPATRPRECVVVRGGGVAAIVLGAGDAIAIRDGEGLQPAVVFAIDGE
CCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCEEEEECCCCCCCEEEEEECCC
GRADSTVLGLEGPADAGLAEVLALGGEGSAQVAHALAARGIAPAAVTGHIVLAGGHSAQT
CCCCCEEEECCCCCCCCHHHHHEECCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCE
QVALTARREVLVVVAAPGGPMAPDGQDAPTDIEVTVTRAPGNERPLPAPLAEPKLDLRVP
EEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECC
AAEARAFRVKAGDYIQIIDVDGRQCSDFLAFDAAALEQGAEFGLDATTTRTLMGAAYPGP
HHHCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHCCCCCCC
GLHSKYYDERQIPLVEVIRDTVGRHDTFALACSAKYYEDMGYPGHANCSDNFNAVLAPYG
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCCCCCCCCEEEECCC
IRTRAGWPAINFFYNTAVDHTNALTMDEPWSRPGDYVLMKALTDLVCATSSCADDIDPAN
CCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GWVPTDIHVRVYDGAESFSKGTAFRMNAAAEPRLTRESAFHPRLAQMTRSFVEYRGFWLP
CCCCCEEEEEEECCCHHHCCCCEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCEECE
TCFTGEGPIAEYWACRETAAVMDLSPLRKFEVTGPDAELLLQRTVTRDMRKLAVGQVVYT
EEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEE
ALTYDHGGMIDDATIFRLAPANFRVVCGEEFTGAWLRDKAREWGLNAFVRSSTDQLHNIA
EEEECCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHEECCCCHHHHEEE
VQGPLSREILAEVIWTGPTQPAIAELKWFRFAVARLGGPMGPALVVSRTGYTGELGYEIW
ECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEE
CHPKDAGAVFDAVWAAGVPKGMKPLGLAALDMLRIEAGLVFAGYDFCDQTDPFEAGIGFA
ECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCEE
VAEKEEDFVGKAALMRRKASPARKMVGLRIEGNDAVGHGDPLYMGRAQVGVVTSATHSPI
EECCCHHHHHHHHHHHHCCCCCHHEEEEEEECCCCCCCCCCEEECCEEEEEEECCCCCCC
LKGQIALARIDVAHGATGTQVEIGKLDGLKKRIGAEIVPFPHFDPQKTRVRA
CCCEEEEEEEEECCCCCCCEEEECCCCCHHHHHCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDASLLPPGPSRSAPATRPRECVVVRGGGVAAIVLGAGDAIAIRDGEGLQPAVVFAIDGE
CCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCEEEEECCCCCCCEEEEEECCC
GRADSTVLGLEGPADAGLAEVLALGGEGSAQVAHALAARGIAPAAVTGHIVLAGGHSAQT
CCCCCEEEECCCCCCCCHHHHHEECCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCE
QVALTARREVLVVVAAPGGPMAPDGQDAPTDIEVTVTRAPGNERPLPAPLAEPKLDLRVP
EEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECC
AAEARAFRVKAGDYIQIIDVDGRQCSDFLAFDAAALEQGAEFGLDATTTRTLMGAAYPGP
HHHCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHCCCCCCC
GLHSKYYDERQIPLVEVIRDTVGRHDTFALACSAKYYEDMGYPGHANCSDNFNAVLAPYG
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCCCCCCCCCCCEEEECCC
IRTRAGWPAINFFYNTAVDHTNALTMDEPWSRPGDYVLMKALTDLVCATSSCADDIDPAN
CCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GWVPTDIHVRVYDGAESFSKGTAFRMNAAAEPRLTRESAFHPRLAQMTRSFVEYRGFWLP
CCCCCEEEEEEECCCHHHCCCCEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCEECE
TCFTGEGPIAEYWACRETAAVMDLSPLRKFEVTGPDAELLLQRTVTRDMRKLAVGQVVYT
EEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEE
ALTYDHGGMIDDATIFRLAPANFRVVCGEEFTGAWLRDKAREWGLNAFVRSSTDQLHNIA
EEEECCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHEECCCCHHHHEEE
VQGPLSREILAEVIWTGPTQPAIAELKWFRFAVARLGGPMGPALVVSRTGYTGELGYEIW
ECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEE
CHPKDAGAVFDAVWAAGVPKGMKPLGLAALDMLRIEAGLVFAGYDFCDQTDPFEAGIGFA
ECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCCEE
VAEKEEDFVGKAALMRRKASPARKMVGLRIEGNDAVGHGDPLYMGRAQVGVVTSATHSPI
EECCCHHHHHHHHHHHHCCCCCHHEEEEEEECCCCCCCCCCEEECCEEEEEEECCCCCCC
LKGQIALARIDVAHGATGTQVEIGKLDGLKKRIGAEIVPFPHFDPQKTRVRA
CCCEEEEEEEEECCCCCCCEEEECCCCCHHHHHCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA