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The map label for this gene is ruvA

Identifier: 154246996

GI number: 154246996

Start: 3406724

End: 3407341

Strand: Direct

Name: ruvA

Synonym: Xaut_3067

Alternate gene names: 154246996

Gene position: 3406724-3407341 (Clockwise)

Preceding gene: 154246995

Following gene: 154246998

Centisome position: 64.17

GC content: 70.06

Gene sequence:

>618_bases
ATGATCGGAAAGTTGAAGGGCGTCGTGGACACGCTGGAGGAGGACCATGTGATCCTCGATGTCCATGGCGTGGGCTATCT
CGTGCACTGTTCCGGCCGCACGCTCTCGGCCCTGCCGCGGGCGGGAGAGGCTGCGGCGCTGTTCATCGAGACCCATGTGC
GCGAGGACCAGATCCGCCTGTTCGGCTTCAGCTCGGCGGCGGAACGGGACTGGTTCCGCCTGCTGCAGGGCATCCAGGGC
ATCGGCACCAAGACCGCCCTGGCCGTGCTCTCCACTTTGAGCGCCTCGGAGCTGACGCAGGCCATCGCGCTGGGCGACAA
GACCACGGTGGCGCGGGCTCCGGGGGTGGGGCCGCGGGTGGCGACGCGCATCATCACCGAGCTGAAGGACAAGATGCCGG
GCTTTTCCGCCTCCGAACCGCTGGCGGCTCAGCTCGGCGGCGGCGGTGTCGCCTCGGCGCAGGGGGGCGCGGCGGCGGAT
GCGGTCTCGGCCCTGGTCAACCTCGGCTATGGCGTGCCGCAGGCCAACGCTGCCATCGCCGCCGCCCTGCGCGGCGCGGG
GGAGGGGGCCAAGACCGAGGTTCTGATCCGGCTGGGGCTGAAGGAACTGGCGAAGTAA

Upstream 100 bases:

>100_bases
CCAACTGCACATGGTGCGCACCGGGCTCGGGGCGCTGGCCACCTTCGTCTTCCTGTGGGCGGCGGTGACCTGATGCCGTT
CCAGCCCTGAAAGGCCTGTG

Downstream 100 bases:

>100_bases
GGGAAAACGCCTGCGCGACCCTCACGGCATCCGGGAGGGCAGCTTCAGGGTGTTCCCGTCCACCGCGAAGGTGCCGTAGC
CCTGATGATGGATGGTGCGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGKLKGVVDTLEEDHVILDVHGVGYLVHCSGRTLSALPRAGEAAALFIETHVREDQIRLFGFSSAAERDWFRLLQGIQG
IGTKTALAVLSTLSASELTQAIALGDKTTVARAPGVGPRVATRIITELKDKMPGFSASEPLAAQLGGGGVASAQGGAAAD
AVSALVNLGYGVPQANAAIAAALRGAGEGAKTEVLIRLGLKELAK

Sequences:

>Translated_205_residues
MIGKLKGVVDTLEEDHVILDVHGVGYLVHCSGRTLSALPRAGEAAALFIETHVREDQIRLFGFSSAAERDWFRLLQGIQG
IGTKTALAVLSTLSASELTQAIALGDKTTVARAPGVGPRVATRIITELKDKMPGFSASEPLAAQLGGGGVASAQGGAAAD
AVSALVNLGYGVPQANAAIAAALRGAGEGAKTEVLIRLGLKELAK
>Mature_205_residues
MIGKLKGVVDTLEEDHVILDVHGVGYLVHCSGRTLSALPRAGEAAALFIETHVREDQIRLFGFSSAAERDWFRLLQGIQG
IGTKTALAVLSTLSASELTQAIALGDKTTVARAPGVGPRVATRIITELKDKMPGFSASEPLAAQLGGGGVASAQGGAAAD
AVSALVNLGYGVPQANAAIAAALRGAGEGAKTEVLIRLGLKELAK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=34.9753694581281, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_XANP2 (A7IJV4)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417954.1
- ProteinModelPortal:   A7IJV4
- SMR:   A7IJV4
- STRING:   A7IJV4
- GeneID:   5424267
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3067
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   XAUT78245:XAUT_3067-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20961; Mature: 20961

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGVVDTLEEDHVILDVHGVGYLVHCSGRTLSALPRAGEAAALFIETHVREDQIRL
CCCCHHHHHHHHCCCCEEEEEECCEEEEEECCCCHHHCCCCCCCEEEEEEECCCCCEEEE
FGFSSAAERDWFRLLQGIQGIGTKTALAVLSTLSASELTQAIALGDKTTVARAPGVGPRV
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHH
ATRIITELKDKMPGFSASEPLAAQLGGGGVASAQGGAAADAVSALVNLGYGVPQANAAIA
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AALRGAGEGAKTEVLIRLGLKELAK
HHHHCCCCCCHHHHHHEECHHHHCC
>Mature Secondary Structure
MIGKLKGVVDTLEEDHVILDVHGVGYLVHCSGRTLSALPRAGEAAALFIETHVREDQIRL
CCCCHHHHHHHHCCCCEEEEEECCEEEEEECCCCHHHCCCCCCCEEEEEEECCCCCEEEE
FGFSSAAERDWFRLLQGIQGIGTKTALAVLSTLSASELTQAIALGDKTTVARAPGVGPRV
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHH
ATRIITELKDKMPGFSASEPLAAQLGGGGVASAQGGAAADAVSALVNLGYGVPQANAAIA
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
AALRGAGEGAKTEVLIRLGLKELAK
HHHHCCCCCCHHHHHHEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA