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The map label for this gene is ruvB

Identifier: 154246998

GI number: 154246998

Start: 3408140

End: 3409171

Strand: Direct

Name: ruvB

Synonym: Xaut_3069

Alternate gene names: 154246998

Gene position: 3408140-3409171 (Clockwise)

Preceding gene: 154246996

Following gene: 154246999

Centisome position: 64.2

GC content: 69.67

Gene sequence:

>1032_bases
ATGAACACCCGCCTCCTCTCGGGCGAGAAGCGCGGCGAAGATGCCGCCGATTCGACGCTGCGGCCCCAGCTCCTCAAGGA
GTTCGTGGGCCAGGCGCAGGCGCGCGCCAATCTGGAAGTGTTCATCAAGGCGGCCCGCGCCCGCGGCGAGGCGCTGGACC
ACGTGCTGTTCGTAGGTCCGCCCGGCCTCGGCAAGACCACGCTGGCCCAGATCATGTCGCGGGAGATGGGGGTGGGCTTC
CGCTCCACCTCCGGCCCGGTGATCGCCAAGGCAGGGGACCTTGCCGCCATCCTCACCAATCTGGAAGAGCGCGACGTGCT
CTTCATCGACGAGATCCACCGCCTCGCGCCGGCGGTGGAGGAAATCCTCTATCCGGCCATGGAGGATTATGAGCTGGACC
TCGTCATCGGCGAAGGGCCGGCGGCGCGCTCGGTGAAGATCGCCCTGCCCAAGTTCACGCTGGTGGGCGCCACCACGCGC
TCGGGCCTGCTCACCACGCCGCTGCGCGACCGCTTCGGCATTCCGGTGCGGCTGCAATTCTACACCGTGGAGGAACTGGA
GAAGATCGTGGTGCGCGGGGCGCGGGTGCTGGGCATCGCCATCGCCCCGGACGGCGCCACCGAGATCGCCCGCCGCGCGC
GGGGAACGCCGCGCATCGCCGGCCGGCTGCTGCGGCGGGTGCGCGACTTCGCCCTGGTGGCCGAAGCCGAGCGCATCGAC
CGCAAGGTGGCCGACCGGGCGCTGCTGGCGCTGGAGGTGGACGCCGCCGGACTCGATGCCATGGATCGGCGCTATCTCAC
CGTCATCGCCGATTATTACGGCGGTGGTCCGGTGGGGGTGGATACGCTCGCGGCTGCGTTGTCCGAGCCGCGCGACGCCA
TCGAGGAGATCGTGGAGCCGTTCCTGGTGCAGCAGGGCTTCATCCAGCGTACGCCGCGCGGGCGGATGCTGACTGCTACC
GCCTTCCGCCATCTTGGACTGCCGGAACCGGTTGTGGCCAGGCCCATGCCCCTGTTCGACGAGGGCGAGTAG

Upstream 100 bases:

>100_bases
TGTGTCTCGCCGCCGCGCGCCTGCGTTCCCCTTCCGTACCCGGCCGGCCCGCACTACAGTCGCGCGAGTCGCCGGCCCCC
AGGGGAGCAAGACCTCTTCC

Downstream 100 bases:

>100_bases
GCCAGCGCCATGCCCATCGACGCGGCCGCGCCGTCAATGTACATCACATTCACATGAGCTGGTCCCGGAACGGAGAAACA
CGGTCCTACCATCACGGCAA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNTRLLSGEKRGEDAADSTLRPQLLKEFVGQAQARANLEVFIKAARARGEALDHVLFVGPPGLGKTTLAQIMSREMGVGF
RSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPAVEEILYPAMEDYELDLVIGEGPAARSVKIALPKFTLVGATTR
SGLLTTPLRDRFGIPVRLQFYTVEELEKIVVRGARVLGIAIAPDGATEIARRARGTPRIAGRLLRRVRDFALVAEAERID
RKVADRALLALEVDAAGLDAMDRRYLTVIADYYGGGPVGVDTLAAALSEPRDAIEEIVEPFLVQQGFIQRTPRGRMLTAT
AFRHLGLPEPVVARPMPLFDEGE

Sequences:

>Translated_343_residues
MNTRLLSGEKRGEDAADSTLRPQLLKEFVGQAQARANLEVFIKAARARGEALDHVLFVGPPGLGKTTLAQIMSREMGVGF
RSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPAVEEILYPAMEDYELDLVIGEGPAARSVKIALPKFTLVGATTR
SGLLTTPLRDRFGIPVRLQFYTVEELEKIVVRGARVLGIAIAPDGATEIARRARGTPRIAGRLLRRVRDFALVAEAERID
RKVADRALLALEVDAAGLDAMDRRYLTVIADYYGGGPVGVDTLAAALSEPRDAIEEIVEPFLVQQGFIQRTPRGRMLTAT
AFRHLGLPEPVVARPMPLFDEGE
>Mature_343_residues
MNTRLLSGEKRGEDAADSTLRPQLLKEFVGQAQARANLEVFIKAARARGEALDHVLFVGPPGLGKTTLAQIMSREMGVGF
RSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPAVEEILYPAMEDYELDLVIGEGPAARSVKIALPKFTLVGATTR
SGLLTTPLRDRFGIPVRLQFYTVEELEKIVVRGARVLGIAIAPDGATEIARRARGTPRIAGRLLRRVRDFALVAEAERID
RKVADRALLALEVDAAGLDAMDRRYLTVIADYYGGGPVGVDTLAAALSEPRDAIEEIVEPFLVQQGFIQRTPRGRMLTAT
AFRHLGLPEPVVARPMPLFDEGE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=63.719512195122, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37351; Mature: 37351

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRLLSGEKRGEDAADSTLRPQLLKEFVGQAQARANLEVFIKAARARGEALDHVLFVGP
CCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCEEEEECC
PGLGKTTLAQIMSREMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDYELDLVIGEGPAARSVKIALPKFTLVGATTRSGLLTTPLRDRFGIPVRLQF
HHHCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEECCCHHHCCCCEEEEE
YTVEELEKIVVRGARVLGIAIAPDGATEIARRARGTPRIAGRLLRRVRDFALVAEAERID
EEHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RKVADRALLALEVDAAGLDAMDRRYLTVIADYYGGGPVGVDTLAAALSEPRDAIEEIVEP
HHHHHHEEEEEEECCCCCCHHHHHHHEEEEHHCCCCCCCHHHHHHHHHCHHHHHHHHHHH
FLVQQGFIQRTPRGRMLTATAFRHLGLPEPVVARPMPLFDEGE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MNTRLLSGEKRGEDAADSTLRPQLLKEFVGQAQARANLEVFIKAARARGEALDHVLFVGP
CCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCEEEEECC
PGLGKTTLAQIMSREMGVGFRSTSGPVIAKAGDLAAILTNLEERDVLFIDEIHRLAPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDYELDLVIGEGPAARSVKIALPKFTLVGATTRSGLLTTPLRDRFGIPVRLQF
HHHCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCEECCCHHHCCCCEEEEE
YTVEELEKIVVRGARVLGIAIAPDGATEIARRARGTPRIAGRLLRRVRDFALVAEAERID
EEHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RKVADRALLALEVDAAGLDAMDRRYLTVIADYYGGGPVGVDTLAAALSEPRDAIEEIVEP
HHHHHHEEEEEEECCCCCCHHHHHHHEEEEHHCCCCCCCHHHHHHHHHCHHHHHHHHHHH
FLVQQGFIQRTPRGRMLTATAFRHLGLPEPVVARPMPLFDEGE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA