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The map label for this gene is metH

Identifier: 154246771

GI number: 154246771

Start: 3156033

End: 3159848

Strand: Direct

Name: metH

Synonym: Xaut_2832

Alternate gene names: 154246771

Gene position: 3156033-3159848 (Clockwise)

Preceding gene: 154246770

Following gene: 154246780

Centisome position: 59.45

GC content: 67.74

Gene sequence:

>3816_bases
ATGTCGTGTTTTCGTCCGGCGACGGACGTCCATCTGTTTCACCGAGGCTGTCCCAAGCCCCGAGCCCTGAGAACTTCAGC
CATGACCGAAACCCGCGCCGCCGACACCTTCTCAGCCCTCGCCCAGGCCGCGTCCGAGCGCATTCTCGTGCTCGACGGCG
CCATGGGCACCATGATCCAGGGGCTGAAGCTGGACGAGGCCGGCTATCGGGGCGCGCGCTTTGCCGACTGGCCGCGCGAC
GTGAAGGGCAACAACGACCTTCTCAGCCTCACCCAGCCCGATGCGGTGCGGGCCATCCACCTCGAATATTTCCGCGCCGG
CGCGGACATGGTGGAAACCAACACCTTCTCCGGCACCTCGATCGCCCAGGCCGACTACGGCATGGAAGAGCTGGTCTACG
AGCTGAATTTCGAGAGCGCCCGCCTCGCCCGGGAGGCAGGCGACATCGCCCAGGCCGAGGACGGCCGCCCGCGTTTCGTC
GCCGGCGCCTTCGGCCCCACCAACCGCACCGCCTCCATCTCCCCGGACGTGAACGACCCCGGCTTCCGCGCGGTGACCTT
CGACGACCTCGCCGGCGCCTATCACGAGCAGGCGCGCGGTCTCGTCGATGGCGGGGCGGACATCCTGCTGGTCGAGACCA
TCTTCGATACGCTGAACGCCAAGGCGGCCATCTTCGCCATCGAGCAATTGTTCGCCGAGCGCGGCATCCGCCTGCCGGTG
ATGATCTCCGGCACCATCACCGATCTCTCCGGCCGCACCCTGTCGGGCCAGACGCCCGCCGCCTTCTGGTATTCGCTCCA
GCATGCCCGGCCGTTCTCCATCGGCCTCAATTGCGCGCTGGGCGCGCGGGAGATGCGCGCCCACGTGGCCGAGATCGGCC
GGGTGGCCGACACGCTGGTGTGCGCCTATCCCAATGCCGGCCTGCCCAACGAATTCGGCATGTATGACGAGAGCCCGCAG
GCCATGGCGGAACTGGTTGGCGAGTTCGCCGCCTCCGGCCTCGTGAACATCGTGGGCGGCTGCTGCGGTACCACGCCAGC
CCACATCCGCGCCATCGCGGAAGCGGTGAAGGGCAAGGCCCCGCGCGTGGTGCCGCAGATCGAGCCGCGCCTGCGCCTCT
CCGGTCTTGAGCCGTTCGAGCTGACGCCGGAAATTCCCTTCGTGAACGTGGGCGAGCGCACCAACGTCACCGGCTCCGCC
CGCTTCCGCAAGCTCATCACCACCGGCGACTTTGCCGCCGCGCTCGCGGTGGCGCGCGACCAGGTGGAGAGCGGCGCGCA
GGTCATCGACATCAACATGGATGAAGGCCTCCTCGACAGCGAGGCGGCCATGGTCACCTTCCTCAACCTCGTCGCCGCCG
AGCCGGACATCGCCAAGGTGCCGGTGATGGTGGACAGCTCGAAGTGGGAGATCATCGAGCAGGGGCTGAAGCGGCTTCAG
GGCAAGGGCATCGTCAATTCCATCTCGATGAAGGAGGGGGAAGACGCCTTCCGCGAGAAGGCCCGGCTCGTGCGCAGCTA
CGGCGCCGCCGTGGTGGTGATGGCCTTCGACGAGGAAGGCCAGGCCGACACCTTCGAGCGCAAGACCCAGATCTGCGCCC
GCGCCTACCGTATCCTGACGGAAGAGCTGGCCTTCCCGCCGGAAGACATCATCTTCGATCCCAACATCTTCGCGGTGGCC
ACCGGCATCGAGGAGCACGCCGGCTATGGCGTCGCCTTCATCGAGGCGACCCGCTGGATCCGGCAGAACCTGCCCCACGC
CCACGTGTCGGGCGGCGTCTCCAACCTGTCGTTCTCGTTCCGCGGCAACGAGCCGGTGCGCGAGGCCATGCACGCGGTTT
TCCTCTATCACGCCATCCAGGCGGGCATGGACATGGGCATCGTCAATGCCGGCCAGCTCGCCGTCTATGACGAGATCGAG
CCCGGACTGCGCGAGGCCTGCGAGGACGTGGTGCTGAACCGCCGTCCCGATGCCACCGAGCGCCTTTTGGAGATCGCCGA
GGGCTTCAAGGGCGCGGCCGGCAAGGAGAAGAAGGAGGCGGATCTCGCCTGGCGCTCCTGGCCAGTGGACAAGCGCCTCG
CCCATGCCCTCGTCAACGGCATCACCGACTTCGTGGAGGCGGACACCGAGGAGGCGCGCCAGTCCGTCGCCCGCCCGCTC
CACGTCATCGAGGGGCCGCTGATGGCGGGCATGAATGTGGTGGGCGACCTGTTCGGCGCCGGCAAGATGTTCCTGCCCCA
GGTGGTGAAGTCCGCCCGCGTGATGAAGCAGGCCGTAGCCTATCTCATGCCCTTCATGGAGAAGGAAAAGGAGGAGATGG
GCGTCACCTCCGCCTCGGCCGCCGGCAAGGTGCTGATGGCCACCGTGAAGGGCGACGTGCACGACATCGGCAAGAACATC
GTGGGCGTCGTGCTCCAGTGCAACAACTACGAGGTCATCGATCTCGGCGTCATGGTGCCCATGGCGAAGATCCTCGAAAC
CGCCAAGGCCGAGAAGGTGGACGTGATCGGCCTTTCCGGCCTCATCACCCCGTCGCTGGACGAGATGGTGAATGTGGCCG
CCGAGATGGAGCGCGAGGGCTTTTCCCTGCCGCTGCTCATCGGCGGCGCCACCACCTCGCGCGTCCACACCGCGGTGAAG
ATCTCGCCCCGCTACGAGCGCGGGCAGGCGGTCTATGTCACCGACGCCAGCCGGGCGGTGGGCGTGGTCTCCAGCCTGCT
CAACAAGGACACGCGCGGCGCTTATGTGGCGGACATCCGCGCCGAATATCGCAAGCTTGCCGAGGCCCATGCGCGGGCCG
ATGCCAACAAGCAGCGCGTGCCCCTCGCCAAGGCGCGCGACAACGCCCTGAAGCTGGACTTTTCCGCTTATGAGGTGCCC
CGGCCTGGCTTCCTCGGAACCCAGATGATCGAGGACCACGACCTCGCCGACCTCGTGCCCTTCATCGACTGGACGCCCTT
CTTCCAGTCCTGGGAGCTGACCGGGCGCTATCCGGCCATCCTTGAAGACCAGGTGGTGGGCGAGCCGGCCCGCGCCCTGT
TCGCCGACGCGCAGGCGATGCTGGAGAAGATGGTTGCGGAGAAGTGGGTGAGCGCCCGTGCCGTGGTGGGCTTCTGGCCG
GCCAATGCCATGGGCGACGACATCGTCCTGTTCCGCGACGACACCCGCAAGACGCCGCTTGCCACCCTCCACACCCTGCG
CCAGCAACTGGCGAAGCGGGACGGGCGCTTCAACCTGGCGCTGTCGGACTTCGTCGCGCCGCTCGAGACCGGGGTCGCCG
ATTATGTCGGCGGCTTCGCGGTGACCACCGGCATCGGCGAGGAGGAGCGGGTGGCGGCCTTCAAGGCGGCCAACGACGAC
TATTCCGCCATCCTGCTGAAGGCCCTGTGCGACCGCCTCGCCGAGGCCTTCGCCGAGCGCCTGCATCATCTGGTGCGGAC
CCGGCTGTGGGGCTATGCGGCCGACGAGGCGCTGGCCAACGACGACCTCATCGCCGAGCGCTATCGCGGCATCCGCCCCG
CGCCCGGCTATCCGGCCCAGCCCGACCACACGGAAAAGGCGACCATCTTCCGCCTGCTCGACGCCACCCACAAGGCGGGC
ATCCAGCTGACGGAGAGCTTCGCCATGTGGCCGGGGGCGGCGGTGTCGGGGCTGTATTTCGCCCACCCCGAGAGCGCCTA
TTTCGGCGTCGGCCGCATCGAGCGCGACCAGGTGGAGGACTATGCCGCCCGCAAGGGCTGGAGCGTGGAGGAGGCCGAGA
AGTGGCTCGCCCCCATCCTCAATTACGATCCCGCGCAGGTGGCCGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CAAAGGCTGTCGCCATCTGAACGCCGGAAGCCCTCTCCCGCTCGCGGGGGAGGGTTGGTAGGGGGCCACAGTCCCATCGG
CGCCGGAAAAATTGGCGACG

Downstream 100 bases:

>100_bases
GGGGCGCCTCCGTCAGTCCCGGCCGTCCCGGTCGCGGCGGCCGGCCACTCCGTGCGAGGTGCCGAGGGGCGATGGCGGCC
TCACGCCGCCGCGCCGGCTC

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1271; Mature: 1270

Protein sequence:

>1271_residues
MSCFRPATDVHLFHRGCPKPRALRTSAMTETRAADTFSALAQAASERILVLDGAMGTMIQGLKLDEAGYRGARFADWPRD
VKGNNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTSIAQADYGMEELVYELNFESARLAREAGDIAQAEDGRPRFV
AGAFGPTNRTASISPDVNDPGFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFAERGIRLPV
MISGTITDLSGRTLSGQTPAAFWYSLQHARPFSIGLNCALGAREMRAHVAEIGRVADTLVCAYPNAGLPNEFGMYDESPQ
AMAELVGEFAASGLVNIVGGCCGTTPAHIRAIAEAVKGKAPRVVPQIEPRLRLSGLEPFELTPEIPFVNVGERTNVTGSA
RFRKLITTGDFAAALAVARDQVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAEPDIAKVPVMVDSSKWEIIEQGLKRLQ
GKGIVNSISMKEGEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILTEELAFPPEDIIFDPNIFAVA
TGIEEHAGYGVAFIEATRWIRQNLPHAHVSGGVSNLSFSFRGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIE
PGLREACEDVVLNRRPDATERLLEIAEGFKGAAGKEKKEADLAWRSWPVDKRLAHALVNGITDFVEADTEEARQSVARPL
HVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKEEMGVTSASAAGKVLMATVKGDVHDIGKNI
VGVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSGLITPSLDEMVNVAAEMEREGFSLPLLIGGATTSRVHTAVK
ISPRYERGQAVYVTDASRAVGVVSSLLNKDTRGAYVADIRAEYRKLAEAHARADANKQRVPLAKARDNALKLDFSAYEVP
RPGFLGTQMIEDHDLADLVPFIDWTPFFQSWELTGRYPAILEDQVVGEPARALFADAQAMLEKMVAEKWVSARAVVGFWP
ANAMGDDIVLFRDDTRKTPLATLHTLRQQLAKRDGRFNLALSDFVAPLETGVADYVGGFAVTTGIGEEERVAAFKAANDD
YSAILLKALCDRLAEAFAERLHHLVRTRLWGYAADEALANDDLIAERYRGIRPAPGYPAQPDHTEKATIFRLLDATHKAG
IQLTESFAMWPGAAVSGLYFAHPESAYFGVGRIERDQVEDYAARKGWSVEEAEKWLAPILNYDPAQVAAAE

Sequences:

>Translated_1271_residues
MSCFRPATDVHLFHRGCPKPRALRTSAMTETRAADTFSALAQAASERILVLDGAMGTMIQGLKLDEAGYRGARFADWPRD
VKGNNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTSIAQADYGMEELVYELNFESARLAREAGDIAQAEDGRPRFV
AGAFGPTNRTASISPDVNDPGFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFAERGIRLPV
MISGTITDLSGRTLSGQTPAAFWYSLQHARPFSIGLNCALGAREMRAHVAEIGRVADTLVCAYPNAGLPNEFGMYDESPQ
AMAELVGEFAASGLVNIVGGCCGTTPAHIRAIAEAVKGKAPRVVPQIEPRLRLSGLEPFELTPEIPFVNVGERTNVTGSA
RFRKLITTGDFAAALAVARDQVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAEPDIAKVPVMVDSSKWEIIEQGLKRLQ
GKGIVNSISMKEGEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILTEELAFPPEDIIFDPNIFAVA
TGIEEHAGYGVAFIEATRWIRQNLPHAHVSGGVSNLSFSFRGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIE
PGLREACEDVVLNRRPDATERLLEIAEGFKGAAGKEKKEADLAWRSWPVDKRLAHALVNGITDFVEADTEEARQSVARPL
HVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKEEMGVTSASAAGKVLMATVKGDVHDIGKNI
VGVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSGLITPSLDEMVNVAAEMEREGFSLPLLIGGATTSRVHTAVK
ISPRYERGQAVYVTDASRAVGVVSSLLNKDTRGAYVADIRAEYRKLAEAHARADANKQRVPLAKARDNALKLDFSAYEVP
RPGFLGTQMIEDHDLADLVPFIDWTPFFQSWELTGRYPAILEDQVVGEPARALFADAQAMLEKMVAEKWVSARAVVGFWP
ANAMGDDIVLFRDDTRKTPLATLHTLRQQLAKRDGRFNLALSDFVAPLETGVADYVGGFAVTTGIGEEERVAAFKAANDD
YSAILLKALCDRLAEAFAERLHHLVRTRLWGYAADEALANDDLIAERYRGIRPAPGYPAQPDHTEKATIFRLLDATHKAG
IQLTESFAMWPGAAVSGLYFAHPESAYFGVGRIERDQVEDYAARKGWSVEEAEKWLAPILNYDPAQVAAAE
>Mature_1270_residues
SCFRPATDVHLFHRGCPKPRALRTSAMTETRAADTFSALAQAASERILVLDGAMGTMIQGLKLDEAGYRGARFADWPRDV
KGNNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTSIAQADYGMEELVYELNFESARLAREAGDIAQAEDGRPRFVA
GAFGPTNRTASISPDVNDPGFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFAERGIRLPVM
ISGTITDLSGRTLSGQTPAAFWYSLQHARPFSIGLNCALGAREMRAHVAEIGRVADTLVCAYPNAGLPNEFGMYDESPQA
MAELVGEFAASGLVNIVGGCCGTTPAHIRAIAEAVKGKAPRVVPQIEPRLRLSGLEPFELTPEIPFVNVGERTNVTGSAR
FRKLITTGDFAAALAVARDQVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAEPDIAKVPVMVDSSKWEIIEQGLKRLQG
KGIVNSISMKEGEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILTEELAFPPEDIIFDPNIFAVAT
GIEEHAGYGVAFIEATRWIRQNLPHAHVSGGVSNLSFSFRGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIEP
GLREACEDVVLNRRPDATERLLEIAEGFKGAAGKEKKEADLAWRSWPVDKRLAHALVNGITDFVEADTEEARQSVARPLH
VIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKEEMGVTSASAAGKVLMATVKGDVHDIGKNIV
GVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSGLITPSLDEMVNVAAEMEREGFSLPLLIGGATTSRVHTAVKI
SPRYERGQAVYVTDASRAVGVVSSLLNKDTRGAYVADIRAEYRKLAEAHARADANKQRVPLAKARDNALKLDFSAYEVPR
PGFLGTQMIEDHDLADLVPFIDWTPFFQSWELTGRYPAILEDQVVGEPARALFADAQAMLEKMVAEKWVSARAVVGFWPA
NAMGDDIVLFRDDTRKTPLATLHTLRQQLAKRDGRFNLALSDFVAPLETGVADYVGGFAVTTGIGEEERVAAFKAANDDY
SAILLKALCDRLAEAFAERLHHLVRTRLWGYAADEALANDDLIAERYRGIRPAPGYPAQPDHTEKATIFRLLDATHKAGI
QLTESFAMWPGAAVSGLYFAHPESAYFGVGRIERDQVEDYAARKGWSVEEAEKWLAPILNYDPAQVAAAE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1251, Percent_Identity=56.3549160671463, Blast_Score=1402, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1221, Percent_Identity=62.981162981163, Blast_Score=1545, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=321, Percent_Identity=27.1028037383178, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535405, Length=1252, Percent_Identity=55.4313099041534, Blast_Score=1368, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 138319; Mature: 138188

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCFRPATDVHLFHRGCPKPRALRTSAMTETRAADTFSALAQAASERILVLDGAMGTMIQ
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHC
GLKLDEAGYRGARFADWPRDVKGNNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTS
CCEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCC
IAQADYGMEELVYELNFESARLAREAGDIAQAEDGRPRFVAGAFGPTNRTASISPDVNDP
HHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCEECCCCCCCC
GFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFAERGIRLPV
CCEEEEHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
MISGTITDLSGRTLSGQTPAAFWYSLQHARPFSIGLNCALGAREMRAHVAEIGRVADTLV
EEECEEECCCCCEECCCCCHHHHHHHHCCCCCEECCEEECCHHHHHHHHHHHHHHHHHEE
CAYPNAGLPNEFGMYDESPQAMAELVGEFAASGLVNIVGGCCGTTPAHIRAIAEAVKGKA
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCC
PRVVPQIEPRLRLSGLEPFELTPEIPFVNVGERTNVTGSARFRKLITTGDFAAALAVARD
CCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
QVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAEPDIAKVPVMVDSSKWEIIEQGLKRLQ
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCEEECCCHHHHHHHHHHHHC
GKGIVNSISMKEGEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILT
CCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EELAFPPEDIIFDPNIFAVATGIEEHAGYGVAFIEATRWIRQNLPHAHVSGGVSNLSFSF
HHHCCCCHHEEECCCCEEEECCHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCCEEEEE
RGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIEPGLREACEDVVLNRRPDATE
CCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEECCCCHHHHHHHHHHHHCCCCCHHH
RLLEIAEGFKGAAGKEKKEADLAWRSWPVDKRLAHALVNGITDFVEADTEEARQSVARPL
HHHHHHHCCCCCCCCCCHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKEEMGVTSASA
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGKVLMATVKGDVHDIGKNIVGVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSG
CCCEEEEEECCCHHHHCCHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECC
LITPSLDEMVNVAAEMEREGFSLPLLIGGATTSRVHTAVKISPRYERGQAVYVTDASRAV
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHEEEEEEECCCCCCCCEEEEECCHHHH
GVVSSLLNKDTRGAYVADIRAEYRKLAEAHARADANKQRVPLAKARDNALKLDFSAYEVP
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCCCC
RPGFLGTQMIEDHDLADLVPFIDWTPFFQSWELTGRYPAILEDQVVGEPARALFADAQAM
CCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
LEKMVAEKWVSARAVVGFWPANAMGDDIVLFRDDTRKTPLATLHTLRQQLAKRDGRFNLA
HHHHHHHHHHHHCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEE
LSDFVAPLETGVADYVGGFAVTTGIGEEERVAAFKAANDDYSAILLKALCDRLAEAFAER
HHHHHHHHHHCHHHHHCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LHHLVRTRLWGYAADEALANDDLIAERYRGIRPAPGYPAQPDHTEKATIFRLLDATHKAG
HHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
IQLTESFAMWPGAAVSGLYFAHPESAYFGVGRIERDQVEDYAARKGWSVEEAEKWLAPIL
CEEEHHHHCCCCHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
NYDPAQVAAAE
CCCCCHHCCCC
>Mature Secondary Structure 
SCFRPATDVHLFHRGCPKPRALRTSAMTETRAADTFSALAQAASERILVLDGAMGTMIQ
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHC
GLKLDEAGYRGARFADWPRDVKGNNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTS
CCEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCC
IAQADYGMEELVYELNFESARLAREAGDIAQAEDGRPRFVAGAFGPTNRTASISPDVNDP
HHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCEECCCCCCCC
GFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFAERGIRLPV
CCEEEEHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEE
MISGTITDLSGRTLSGQTPAAFWYSLQHARPFSIGLNCALGAREMRAHVAEIGRVADTLV
EEECEEECCCCCEECCCCCHHHHHHHHCCCCCEECCEEECCHHHHHHHHHHHHHHHHHEE
CAYPNAGLPNEFGMYDESPQAMAELVGEFAASGLVNIVGGCCGTTPAHIRAIAEAVKGKA
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCC
PRVVPQIEPRLRLSGLEPFELTPEIPFVNVGERTNVTGSARFRKLITTGDFAAALAVARD
CCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
QVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAEPDIAKVPVMVDSSKWEIIEQGLKRLQ
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCEEECCCHHHHHHHHHHHHC
GKGIVNSISMKEGEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILT
CCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EELAFPPEDIIFDPNIFAVATGIEEHAGYGVAFIEATRWIRQNLPHAHVSGGVSNLSFSF
HHHCCCCHHEEECCCCEEEECCHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCCEEEEE
RGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIEPGLREACEDVVLNRRPDATE
CCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEECCCCHHHHHHHHHHHHCCCCCHHH
RLLEIAEGFKGAAGKEKKEADLAWRSWPVDKRLAHALVNGITDFVEADTEEARQSVARPL
HHHHHHHCCCCCCCCCCHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKEEMGVTSASA
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGKVLMATVKGDVHDIGKNIVGVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSG
CCCEEEEEECCCHHHHCCHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECC
LITPSLDEMVNVAAEMEREGFSLPLLIGGATTSRVHTAVKISPRYERGQAVYVTDASRAV
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHEEEEEEECCCCCCCCEEEEECCHHHH
GVVSSLLNKDTRGAYVADIRAEYRKLAEAHARADANKQRVPLAKARDNALKLDFSAYEVP
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCCCC
RPGFLGTQMIEDHDLADLVPFIDWTPFFQSWELTGRYPAILEDQVVGEPARALFADAQAM
CCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHH
LEKMVAEKWVSARAVVGFWPANAMGDDIVLFRDDTRKTPLATLHTLRQQLAKRDGRFNLA
HHHHHHHHHHHHCEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEE
LSDFVAPLETGVADYVGGFAVTTGIGEEERVAAFKAANDDYSAILLKALCDRLAEAFAER
HHHHHHHHHHCHHHHHCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LHHLVRTRLWGYAADEALANDDLIAERYRGIRPAPGYPAQPDHTEKATIFRLLDATHKAG
HHHHHHHHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
IQLTESFAMWPGAAVSGLYFAHPESAYFGVGRIERDQVEDYAARKGWSVEEAEKWLAPIL
CEEEHHHHCCCCHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
NYDPAQVAAAE
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]