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The map label for this gene is dppB [H]

Identifier: 154246701

GI number: 154246701

Start: 3059485

End: 3060453

Strand: Direct

Name: dppB [H]

Synonym: Xaut_2762

Alternate gene names: 154246701

Gene position: 3059485-3060453 (Clockwise)

Preceding gene: 154246700

Following gene: 154246702

Centisome position: 57.63

GC content: 66.77

Gene sequence:

>969_bases
GTGGCTCGATACCTGAAGCGGTCGCTCGGGCAGATTGCCTTCGTCATCCTCGGCATCGCCATCATCAACTTCTTCCTGCT
GCGCCTCGCGCCGGGCGATGCGGCGCAGGTGATGGCGGGGGAGGCGGGATCGGCGACGCCCGAATACATGGCGGCGCTCC
GCCAGCAGTTCGGCCTCGACCAGCCGCTTTATGTGCAATTTCTTGCTTACCTGAAGAATCTGCTGACGCTCAACCTCGGC
TATTCCTTCCGGCAGGGCATGCCGGTGTCGGAGCTCATCGCCCAGCGCCTGCCGGCGACCTTGCTGCTCATGGGAACCTC
CATCGCCTTTGCGGTCAGCGTCGGCGGCACGCTGGGGTTCCTCGCCGCGCGCCATGCCGGCAAGCTGGCGGACACGGTGA
TCTCCTCCGTCGCGCTGGTGTTCTACGCGACGCCGGTGTTCTGGATCGGCGTGATGCTGGTGGTGGTGTTCTCGGTGCTG
CTCGACTGGCTGCCCGTGGGCGGCATGGCCAGCATCGAATCCGGCCTCACCGGGCTTGGCTATGCCGCCGATGTGGCGCG
GCACCTCATCCTGCCGGCGTTGACGCTGGGCCTGTTCTATCTGGCCATCTACACCCGCCTCATGCGCGCCTCCATGCTGG
AGGTCTACGGGCAGGATTTCGTGCGCACGGCGCGGGCCAAGGGGGTGCGGCCTCGGCGCATCGCCCTGCGCCACGTGCTG
CGCAACGCGCTGTTGCCCATCGTGACCACGCTGGGCGTGCAGCTCGGCTCCATCCTCGGCGGGGCGATCCTGGTGGAGAC
GGTGTTTGCATGGCCGGGCCTCGGCCGGCTCGCCTTCGAGGCGCTGTTCCAGCGCGACCTCAACCTGCTGCTGGGCATCC
TGTTCTGCTCGTCGGTGGTGGTGGTCATCGTCAATCTCGCGGTGGATCTCGCCTATACGGTGCTCGATCCGCGCATCGAG
CTGAGCTGA

Upstream 100 bases:

>100_bases
CCTCAAGGGCGCGGTGGAGCAGGGCGACCAGGTCTATTCCTCGCTCCGCAACGCCTGGTTCGATGGGCCCAACGCCGACG
CGCCGAAGGGGAACTGAGGC

Downstream 100 bases:

>100_bases
GGAGGTTTGACCATGGCCCTCCTCGATTTCGCATCCCCGCCCGTGTCGTCCCAGACGACCGCCGACGCGCCCCGCGACAC
GCTGCTGCGCCGCTTGCTGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MARYLKRSLGQIAFVILGIAIINFFLLRLAPGDAAQVMAGEAGSATPEYMAALRQQFGLDQPLYVQFLAYLKNLLTLNLG
YSFRQGMPVSELIAQRLPATLLLMGTSIAFAVSVGGTLGFLAARHAGKLADTVISSVALVFYATPVFWIGVMLVVVFSVL
LDWLPVGGMASIESGLTGLGYAADVARHLILPALTLGLFYLAIYTRLMRASMLEVYGQDFVRTARAKGVRPRRIALRHVL
RNALLPIVTTLGVQLGSILGGAILVETVFAWPGLGRLAFEALFQRDLNLLLGILFCSSVVVVIVNLAVDLAYTVLDPRIE
LS

Sequences:

>Translated_322_residues
MARYLKRSLGQIAFVILGIAIINFFLLRLAPGDAAQVMAGEAGSATPEYMAALRQQFGLDQPLYVQFLAYLKNLLTLNLG
YSFRQGMPVSELIAQRLPATLLLMGTSIAFAVSVGGTLGFLAARHAGKLADTVISSVALVFYATPVFWIGVMLVVVFSVL
LDWLPVGGMASIESGLTGLGYAADVARHLILPALTLGLFYLAIYTRLMRASMLEVYGQDFVRTARAKGVRPRRIALRHVL
RNALLPIVTTLGVQLGSILGGAILVETVFAWPGLGRLAFEALFQRDLNLLLGILFCSSVVVVIVNLAVDLAYTVLDPRIE
LS
>Mature_321_residues
ARYLKRSLGQIAFVILGIAIINFFLLRLAPGDAAQVMAGEAGSATPEYMAALRQQFGLDQPLYVQFLAYLKNLLTLNLGY
SFRQGMPVSELIAQRLPATLLLMGTSIAFAVSVGGTLGFLAARHAGKLADTVISSVALVFYATPVFWIGVMLVVVFSVLL
DWLPVGGMASIESGLTGLGYAADVARHLILPALTLGLFYLAIYTRLMRASMLEVYGQDFVRTARAKGVRPRRIALRHVLR
NALLPIVTTLGVQLGSILGGAILVETVFAWPGLGRLAFEALFQRDLNLLLGILFCSSVVVVIVNLAVDLAYTVLDPRIEL
S

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=40.0593471810089, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=39.2523364485981, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=38.6075949367089, Blast_Score=210, Evalue=9e-56,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=38.7878787878788, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=33.4384858044164, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788504, Length=364, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34756; Mature: 34625

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYLKRSLGQIAFVILGIAIINFFLLRLAPGDAAQVMAGEAGSATPEYMAALRQQFGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCC
QPLYVQFLAYLKNLLTLNLGYSFRQGMPVSELIAQRLPATLLLMGTSIAFAVSVGGTLGF
CHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHH
LAARHAGKLADTVISSVALVFYATPVFWIGVMLVVVFSVLLDWLPVGGMASIESGLTGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
YAADVARHLILPALTLGLFYLAIYTRLMRASMLEVYGQDFVRTARAKGVRPRRIALRHVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RNALLPIVTTLGVQLGSILGGAILVETVFAWPGLGRLAFEALFQRDLNLLLGILFCSSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIVNLAVDLAYTVLDPRIELS
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARYLKRSLGQIAFVILGIAIINFFLLRLAPGDAAQVMAGEAGSATPEYMAALRQQFGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCC
QPLYVQFLAYLKNLLTLNLGYSFRQGMPVSELIAQRLPATLLLMGTSIAFAVSVGGTLGF
CHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHH
LAARHAGKLADTVISSVALVFYATPVFWIGVMLVVVFSVLLDWLPVGGMASIESGLTGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
YAADVARHLILPALTLGLFYLAIYTRLMRASMLEVYGQDFVRTARAKGVRPRRIALRHVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RNALLPIVTTLGVQLGSILGGAILVETVFAWPGLGRLAFEALFQRDLNLLLGILFCSSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIVNLAVDLAYTVLDPRIELS
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]