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The map label for this gene is atzB [H]

Identifier: 154246680

GI number: 154246680

Start: 3034894

End: 3036258

Strand: Direct

Name: atzB [H]

Synonym: Xaut_2741

Alternate gene names: 154246680

Gene position: 3034894-3036258 (Clockwise)

Preceding gene: 154246679

Following gene: 154246683

Centisome position: 57.17

GC content: 69.82

Gene sequence:

>1365_bases
ATGGCCCAGACGCTGCTCGCCCGCAACGCCCTCGTCCTCGTCACCATGGATGGAGAGCGCCGGGAGATCCCGGGCGGTGG
GCTCTATGCCGAAGACGGGCGTATCGTCGCGGTGGGACGCGCCGCTGATCTGCCGGCGCAGGCGGACGAAGTCATCGACC
TTGCCGGCCATGTGGTGATCCCGGGCCTCGTCAACACCCACCACCACATGGTGCAGAGCCTGACCCGCGCGGTGCCGGCG
GCGCAGGACGGCGAATTGTTCGACTGGCTGCGCGCGCTGTATCCGCTGTGGGCGGGGCTGACCGGCGAGATGGTGGAGAC
GGCGACCCTGACCGCCATGGCGGAGCTGATCCTCTCCGGCTGCACCACGTCGTCGGACCATCTCTACATCTATCCCAACG
GGGTGCGGCTCGACGATTCCATCCGCGCTGCGCGGCAGGTCGGAATGCGTTTCCACGCCGCCCGCGGCTCCATGAGCGTG
GGCGAGAGCAAGGGCGGCCTGCCTCCCGACCGGGTGGTGGAGGACGAGGGCTTCGTGATGAAGGACGCCGAGCGCCTTAT
CGGCGCCTATCACGACCCCGACCGCTTCTCCATGCTGCGGGTGGTGCTGGCGCCGTGCTCGCCCTTCACCGTGAGCCACG
ACCTGATGCGGGACACGCTCCGCCTCGCCCGCGCCAACGGCCTGACCCTGCATACGCATCTCGCCGAGAACGATTCGGAT
ATCGCCTTTTCCCACAAGACCTTCGGCATGGGCCCCACCGAATATGTCCGCGAGCTGGGCTGGGTTGGGCCGGACGTGTG
GCATGCTCACTGCGTGAAGCTGGACGAGGCGGGTATCGCCCTGTTCGCCCGCACGGGCACAGGCATAGCCCATTGCCCGT
GCTCCAACATGCGCCTCGCCTCGGGCATCGCGCCGGTGAAGCGGTTCCGCGCGGAAGGCATCCCGGTGGGCCTCGGGGTG
GACGGCTCGGCCTCCAACGACAGCGGCCATCTTCTGGCCGAGGCACGCCAGGCCATGCTGCTCCAGCGCGTAGCCTTCGG
CCCCGACGCCATGAGCGCGCGCACGGCGCTGGAACTGGCGACTTTGGGCGGCGCGCGGGTGCTGGGACGGGACGACATCG
GCGCGCTGGCCCCGGACATGGCGGCGGATTTCGTCGCCTTCGACATGTCGGCGCTGGCCTATGCCGGGGCGCTGCACGAT
CCGGTCGCGGCGCTCCTGTTCTGCGCGCCGCAGCAGGTGAGCCTGAGCATCATCAACGGCCGCGTGGTGGTGCGCGACGG
CCGCCTCCTCACCATCGACTTGCCGGCGACGGCGCGGCGGCACAATTCCTTCGCCGCCGAGCTGGCGGCGCTGGCGCCGT
CCTGA

Upstream 100 bases:

>100_bases
TGGCCCTGACGGGATTCCCTTGGGTCCCCATCGCTCCTAACATCGGGTCGCCGATGGCGCTTGGCTCTTGATTCCGGGCG
CCCTGTTCCGCGGAGACCCC

Downstream 100 bases:

>100_bases
TGGCGGAAGTGTCGCTGCTCAGAACTTGTGGAAGATGAAGAAGGCCCCGGCCGAGATGAAGGCAAACCCCACAAGGTGGT
TCCAGCCCAGCGGCTCCTTC

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAQTLLARNALVLVTMDGERREIPGGGLYAEDGRIVAVGRAADLPAQADEVIDLAGHVVIPGLVNTHHHMVQSLTRAVPA
AQDGELFDWLRALYPLWAGLTGEMVETATLTAMAELILSGCTTSSDHLYIYPNGVRLDDSIRAARQVGMRFHAARGSMSV
GESKGGLPPDRVVEDEGFVMKDAERLIGAYHDPDRFSMLRVVLAPCSPFTVSHDLMRDTLRLARANGLTLHTHLAENDSD
IAFSHKTFGMGPTEYVRELGWVGPDVWHAHCVKLDEAGIALFARTGTGIAHCPCSNMRLASGIAPVKRFRAEGIPVGLGV
DGSASNDSGHLLAEARQAMLLQRVAFGPDAMSARTALELATLGGARVLGRDDIGALAPDMAADFVAFDMSALAYAGALHD
PVAALLFCAPQQVSLSIINGRVVVRDGRLLTIDLPATARRHNSFAAELAALAPS

Sequences:

>Translated_454_residues
MAQTLLARNALVLVTMDGERREIPGGGLYAEDGRIVAVGRAADLPAQADEVIDLAGHVVIPGLVNTHHHMVQSLTRAVPA
AQDGELFDWLRALYPLWAGLTGEMVETATLTAMAELILSGCTTSSDHLYIYPNGVRLDDSIRAARQVGMRFHAARGSMSV
GESKGGLPPDRVVEDEGFVMKDAERLIGAYHDPDRFSMLRVVLAPCSPFTVSHDLMRDTLRLARANGLTLHTHLAENDSD
IAFSHKTFGMGPTEYVRELGWVGPDVWHAHCVKLDEAGIALFARTGTGIAHCPCSNMRLASGIAPVKRFRAEGIPVGLGV
DGSASNDSGHLLAEARQAMLLQRVAFGPDAMSARTALELATLGGARVLGRDDIGALAPDMAADFVAFDMSALAYAGALHD
PVAALLFCAPQQVSLSIINGRVVVRDGRLLTIDLPATARRHNSFAAELAALAPS
>Mature_453_residues
AQTLLARNALVLVTMDGERREIPGGGLYAEDGRIVAVGRAADLPAQADEVIDLAGHVVIPGLVNTHHHMVQSLTRAVPAA
QDGELFDWLRALYPLWAGLTGEMVETATLTAMAELILSGCTTSSDHLYIYPNGVRLDDSIRAARQVGMRFHAARGSMSVG
ESKGGLPPDRVVEDEGFVMKDAERLIGAYHDPDRFSMLRVVLAPCSPFTVSHDLMRDTLRLARANGLTLHTHLAENDSDI
AFSHKTFGMGPTEYVRELGWVGPDVWHAHCVKLDEAGIALFARTGTGIAHCPCSNMRLASGIAPVKRFRAEGIPVGLGVD
GSASNDSGHLLAEARQAMLLQRVAFGPDAMSARTALELATLGGARVLGRDDIGALAPDMAADFVAFDMSALAYAGALHDP
VAALLFCAPQQVSLSIINGRVVVRDGRLLTIDLPATARRHNSFAAELAALAPS

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=370, Percent_Identity=23.2432432432432, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1789249, Length=427, Percent_Identity=28.8056206088993, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540282, Length=394, Percent_Identity=22.8426395939086, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319963, Length=339, Percent_Identity=26.8436578171091, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643849, Length=400, Percent_Identity=25, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 48341; Mature: 48210

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTLLARNALVLVTMDGERREIPGGGLYAEDGRIVAVGRAADLPAQADEVIDLAGHVVI
CCCCCEECCEEEEEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHCCCEEE
PGLVNTHHHMVQSLTRAVPAAQDGELFDWLRALYPLWAGLTGEMVETATLTAMAELILSG
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
CTTSSDHLYIYPNGVRLDDSIRAARQVGMRFHAARGSMSVGESKGGLPPDRVVEDEGFVM
CCCCCCEEEEECCCEEECHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHEECCCCCEE
KDAERLIGAYHDPDRFSMLRVVLAPCSPFTVSHDLMRDTLRLARANGLTLHTHLAENDSD
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
IAFSHKTFGMGPTEYVRELGWVGPDVWHAHCVKLDEAGIALFARTGTGIAHCPCSNMRLA
EEEECCCCCCCHHHHHHHHCCCCCCHHHHHHEEECCCCEEEEEECCCCEEECCCCCCCHH
SGIAPVKRFRAEGIPVGLGVDGSASNDSGHLLAEARQAMLLQRVAFGPDAMSARTALELA
HCCHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGGARVLGRDDIGALAPDMAADFVAFDMSALAYAGALHDPVAALLFCAPQQVSLSIING
HCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
RVVVRDGRLLTIDLPATARRHNSFAAELAALAPS
EEEEECCEEEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQTLLARNALVLVTMDGERREIPGGGLYAEDGRIVAVGRAADLPAQADEVIDLAGHVVI
CCCCEECCEEEEEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHCCCEEE
PGLVNTHHHMVQSLTRAVPAAQDGELFDWLRALYPLWAGLTGEMVETATLTAMAELILSG
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
CTTSSDHLYIYPNGVRLDDSIRAARQVGMRFHAARGSMSVGESKGGLPPDRVVEDEGFVM
CCCCCCEEEEECCCEEECHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHEECCCCCEE
KDAERLIGAYHDPDRFSMLRVVLAPCSPFTVSHDLMRDTLRLARANGLTLHTHLAENDSD
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
IAFSHKTFGMGPTEYVRELGWVGPDVWHAHCVKLDEAGIALFARTGTGIAHCPCSNMRLA
EEEECCCCCCCHHHHHHHHCCCCCCHHHHHHEEECCCCEEEEEECCCCEEECCCCCCCHH
SGIAPVKRFRAEGIPVGLGVDGSASNDSGHLLAEARQAMLLQRVAFGPDAMSARTALELA
HCCHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGGARVLGRDDIGALAPDMAADFVAFDMSALAYAGALHDPVAALLFCAPQQVSLSIING
HCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
RVVVRDGRLLTIDLPATARRHNSFAAELAALAPS
EEEEECCEEEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]