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The map label for this gene is uvrB [H]

Identifier: 154246683

GI number: 154246683

Start: 3037680

End: 3040280

Strand: Direct

Name: uvrB [H]

Synonym: Xaut_2744

Alternate gene names: 154246683

Gene position: 3037680-3040280 (Clockwise)

Preceding gene: 154246680

Following gene: 154246684

Centisome position: 57.22

GC content: 67.4

Gene sequence:

>2601_bases
ATGGCCAAAGCATCCCGTCCCGGTAAGCTCGGAGAGCGCTCCCAGCGTCATTTCGAGCCGGCGCCCCAGCAGGCGCTGGA
TCCTGAACTCGCACAGTCCCTCGGGCTCGCACCCGGGGACGTGAGCCTCGATTTCGGGTCCGCCGGGGCCTCCGCCACGG
TGCAGGCGCTGTCGCAGCTGATCGAGAACGGGCGGCCGGAGGTCAACGGCCAGACCTGGGTGCCCCATCGTCCGCCGCGT
CCGGAGAAGTCCGAGGGCGGCGTCAGCTTCATCATGAAGAGCGATTTCGAGCCCGCCGGCGACCAGCCGCAGGCCATCGC
CGAGCTGTGCGCCCAGGCGCAGGCCGGCGAGCGCGACCAGGTGCTGCTAGGCGTCACCGGATCGGGCAAGACCTTCACCA
TGGCCAAGGTAATCGAGCAGCTCCAGCGCCCGGCCATCGTGCTCGCACCCAACAAGACGCTGGCGGCCCAGCTCTATGGC
GAGTTCAAGAGCTTTTTCCCCGACAATGCGGTGGAATATTTCGTCTCCTACTACGATTACTACCAGCCGGAGGCCTATGT
ACCCCGGACGGATACCTATATCGAGAAGGAATCCTCCATCAACGAGCAGATCGACCGCATGCGCCATGCGGCGACACGTG
CCCTTCTGGAGCGCGACGATGTGATCATCGTCGCCTCGGTGTCGTGCATCTACGGCATCGGCTCGGTCGAGACCTATTCG
GCCATGACCTTCGACATCAAGGTGGGCGAGCGCATCGACCAGCGCGGCCTGCTGGCCGATCTCGTGGCCCTGCAATACAA
GCGCATCCAGTCGGATTTCGCCCGCGGCACCTTCCGGGTGCGCGGCGACGTGGTGGAGATCTTCCCCGCCCACTACGAGG
ATCGCGCCTGGCGCGTCTCCCTGTTCGGCGACGAAGTGGAGAGCATCGCCGAGTTCGACCCGCTCACCGGCCACAAGAGC
GGTGACATGAAGAGCGTGCGCGTCTACGCCGCCTCCCATTACGTCACCCCGCGTCCGACGCTGATCCAGGCCATCACCGG
CATCAAGGCCGAGCTGAAGATGCGCCTCGACGAGCTCTACAAGATGGGCCGCCTGCTGGAGGCCCAGCGGCTGGAGCAGC
GCACCCGATACGACCTTGAGATGATGGAGGCCACCGGCAGTTGCGCCGGCATCGAGAATTATTCGCGCTGGCTCACCGGC
CGCAAGCCGGGCGAGCCGCCGCCGACCCTGTTCGAATATGTGCCCGACAATTCCCTCGTCTTCATCGACGAGAGCCATGT
GACCGTGCCGCAGATCGGCGCCATGTATCGCGGCGACTTCCGCCGCAAGGCGACGCTGGCGGAATACGGCTTCCGCCTGC
CGAGCTGCATGGACAATCGCCCGCTGCGCTTCGAGGAATGGGAGGCCATGCGGCCGCAGACGGTCCATGTCTCCGCCACC
CCCGGCACCTGGGAGATGGAGAAGACCGGCGGCGTGTTCGTGGAGCAGGTGATCCGGCCCACGGGGCTGATCGATCCGCC
GGTGGAAGTGCGCCCCGCCCGCACCCAGGTGGACGATCTGCTGGGCGAAGTGCGGGCCTTCGCGGCGAAAGGTTACCGTA
CGCTGGTGACGGTACTCACCAAGCGCATGGCCGAGGACCTCACCGAATATCTGCACGAGCACGGCATCCGCGTGCGTTAC
ATGCATTCCGATATCGACACCATCGAGCGCATCGAGATCATCCGCGACCTCAGGCTTGGGGCGTTCGACGTGCTCATCGG
CATCAACCTGCTGCGCGAGGGCCTCGACATCCCGGAGTGTGGGCTGGTGGCCATCCTGGACGCGGACAAGGAAGGCTTCC
TGCGCTCGGAGACCTCGCTGGTGCAGACCATCGGCCGCGCTGCCCGCAACGTGGACGGCCGCGTCATCCTCTATGCCGAC
CGGGTCACCGGCTCCATGGAGCGGGCCATGGCAGAGACCTCCCGCCGCCGCGAGAAGCAGGTAGCCTACAACACCGCCCA
CGGCATCACGCCGGAGAGCGTGAAGAAGGCCATCGGCGACATTCTCAATTCCGTCTACGAGCGCGACCACGTGCAGGTGG
ATGCGGGCCTGGCGGAGGAGGGGGCCGCCTTCGGGCACAACCTCAAGGCGGTGATGGCGGACCTGGAGAAGCGGATGCGC
GCCGCCGCCGCGGACCTCGACTTCGAGACCGCCGCCCGCCTGCGCGACGAGATCCGCCGGCTGGAGGCGACCGAGCTGGC
GGTGGCCGACGATCCCCTCGCCCGGCAGGAGGCGGTGGAGGACAAGTCCGGCGGCTTCCGGGGTCCGCGCAAATACGGCA
AGGCGGCCAACCTGCCGCCCAAGGAAGACGCCGGCAAGCTCTTGCCGCGCGGCCGCGGGGCGGGGCGCAAGCCGCGCTCT
GAACCCGATGACGAAGGGATGGGCGAGGAGCAGGCGGGCTACACCGCTCCGGTCACCCGCGCCCACAAGCCCTCCCTCGA
CGACATGGGTCCCGGCTCGGACCGCGCCGTGCCCATCACGGAAGACACCTTCCGCCCCGGCCCGCGCCCCGATCCCGGCA
CCAAGGGCTACCGGAAGGGCGGGCGACGGTCGAAGGGGTAA

Upstream 100 bases:

>100_bases
TTTTGCATCACTGGATGCATGACATTTTCCGAACTTTGGCGACGCGAGGTCTCGCGCTCTGCGTCTTTCCTAACGGGGGG
ATCGCCCCCATATTCCCCCT

Downstream 100 bases:

>100_bases
AACCAAGGGCCCGTAAACAAAGCTCACGGGCCCTTGGTAAAGCTCGCGCGGCGCTTGAGCGGAGCCACTTGGCGTCGGTC
AATGACCGAGGCCGATGGTA

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 866; Mature: 865

Protein sequence:

>866_residues
MAKASRPGKLGERSQRHFEPAPQQALDPELAQSLGLAPGDVSLDFGSAGASATVQALSQLIENGRPEVNGQTWVPHRPPR
PEKSEGGVSFIMKSDFEPAGDQPQAIAELCAQAQAGERDQVLLGVTGSGKTFTMAKVIEQLQRPAIVLAPNKTLAAQLYG
EFKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRALLERDDVIIVASVSCIYGIGSVETYS
AMTFDIKVGERIDQRGLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRVSLFGDEVESIAEFDPLTGHKS
GDMKSVRVYAASHYVTPRPTLIQAITGIKAELKMRLDELYKMGRLLEAQRLEQRTRYDLEMMEATGSCAGIENYSRWLTG
RKPGEPPPTLFEYVPDNSLVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWEAMRPQTVHVSAT
PGTWEMEKTGGVFVEQVIRPTGLIDPPVEVRPARTQVDDLLGEVRAFAAKGYRTLVTVLTKRMAEDLTEYLHEHGIRVRY
MHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYAD
RVTGSMERAMAETSRRREKQVAYNTAHGITPESVKKAIGDILNSVYERDHVQVDAGLAEEGAAFGHNLKAVMADLEKRMR
AAAADLDFETAARLRDEIRRLEATELAVADDPLARQEAVEDKSGGFRGPRKYGKAANLPPKEDAGKLLPRGRGAGRKPRS
EPDDEGMGEEQAGYTAPVTRAHKPSLDDMGPGSDRAVPITEDTFRPGPRPDPGTKGYRKGGRRSKG

Sequences:

>Translated_866_residues
MAKASRPGKLGERSQRHFEPAPQQALDPELAQSLGLAPGDVSLDFGSAGASATVQALSQLIENGRPEVNGQTWVPHRPPR
PEKSEGGVSFIMKSDFEPAGDQPQAIAELCAQAQAGERDQVLLGVTGSGKTFTMAKVIEQLQRPAIVLAPNKTLAAQLYG
EFKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRALLERDDVIIVASVSCIYGIGSVETYS
AMTFDIKVGERIDQRGLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRVSLFGDEVESIAEFDPLTGHKS
GDMKSVRVYAASHYVTPRPTLIQAITGIKAELKMRLDELYKMGRLLEAQRLEQRTRYDLEMMEATGSCAGIENYSRWLTG
RKPGEPPPTLFEYVPDNSLVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWEAMRPQTVHVSAT
PGTWEMEKTGGVFVEQVIRPTGLIDPPVEVRPARTQVDDLLGEVRAFAAKGYRTLVTVLTKRMAEDLTEYLHEHGIRVRY
MHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYAD
RVTGSMERAMAETSRRREKQVAYNTAHGITPESVKKAIGDILNSVYERDHVQVDAGLAEEGAAFGHNLKAVMADLEKRMR
AAAADLDFETAARLRDEIRRLEATELAVADDPLARQEAVEDKSGGFRGPRKYGKAANLPPKEDAGKLLPRGRGAGRKPRS
EPDDEGMGEEQAGYTAPVTRAHKPSLDDMGPGSDRAVPITEDTFRPGPRPDPGTKGYRKGGRRSKG
>Mature_865_residues
AKASRPGKLGERSQRHFEPAPQQALDPELAQSLGLAPGDVSLDFGSAGASATVQALSQLIENGRPEVNGQTWVPHRPPRP
EKSEGGVSFIMKSDFEPAGDQPQAIAELCAQAQAGERDQVLLGVTGSGKTFTMAKVIEQLQRPAIVLAPNKTLAAQLYGE
FKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRALLERDDVIIVASVSCIYGIGSVETYSA
MTFDIKVGERIDQRGLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRVSLFGDEVESIAEFDPLTGHKSG
DMKSVRVYAASHYVTPRPTLIQAITGIKAELKMRLDELYKMGRLLEAQRLEQRTRYDLEMMEATGSCAGIENYSRWLTGR
KPGEPPPTLFEYVPDNSLVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWEAMRPQTVHVSATP
GTWEMEKTGGVFVEQVIRPTGLIDPPVEVRPARTQVDDLLGEVRAFAAKGYRTLVTVLTKRMAEDLTEYLHEHGIRVRYM
HSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADR
VTGSMERAMAETSRRREKQVAYNTAHGITPESVKKAIGDILNSVYERDHVQVDAGLAEEGAAFGHNLKAVMADLEKRMRA
AAADLDFETAARLRDEIRRLEATELAVADDPLARQEAVEDKSGGFRGPRKYGKAANLPPKEDAGKLLPRGRGAGRKPRSE
PDDEGMGEEQAGYTAPVTRAHKPSLDDMGPGSDRAVPITEDTFRPGPRPDPGTKGYRKGGRRSKG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=677, Percent_Identity=59.6750369276219, Blast_Score=792, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 96133; Mature: 96002

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKASRPGKLGERSQRHFEPAPQQALDPELAQSLGLAPGDVSLDFGSAGASATVQALSQL
CCCCCCCCCCCCHHHHCCCCCCHHHCCHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
IENGRPEVNGQTWVPHRPPRPEKSEGGVSFIMKSDFEPAGDQPQAIAELCAQAQAGERDQ
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
VLLGVTGSGKTFTMAKVIEQLQRPAIVLAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDY
EEEEECCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQPEAYVPRTDTYIEKESSINEQIDRMRHAATRALLERDDVIIVASVSCIYGIGSVETYS
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCE
AMTFDIKVGERIDQRGLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRVS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCCEEEE
LFGDEVESIAEFDPLTGHKSGDMKSVRVYAASHYVTPRPTLIQAITGIKAELKMRLDELY
ECCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KMGRLLEAQRLEQRTRYDLEMMEATGSCAGIENYSRWLTGRKPGEPPPTLFEYVPDNSLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEE
FIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWEAMRPQTVHVSAT
EEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEC
PGTWEMEKTGGVFVEQVIRPTGLIDPPVEVRPARTQVDDLLGEVRAFAAKGYRTLVTVLT
CCCEEEHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
KRMAEDLTEYLHEHGIRVRYMHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPEC
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADRVTGSMERAMAETSRRREKQ
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
VAYNTAHGITPESVKKAIGDILNSVYERDHVQVDAGLAEEGAAFGHNLKAVMADLEKRMR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCHHHCCHHHHHHHHHHHHHH
AAAADLDFETAARLRDEIRRLEATELAVADDPLARQEAVEDKSGGFRGPRKYGKAANLPP
HHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCC
KEDAGKLLPRGRGAGRKPRSEPDDEGMGEEQAGYTAPVTRAHKPSLDDMGPGSDRAVPIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC
EDTFRPGPRPDPGTKGYRKGGRRSKG
CCCCCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
AKASRPGKLGERSQRHFEPAPQQALDPELAQSLGLAPGDVSLDFGSAGASATVQALSQL
CCCCCCCCCCCHHHHCCCCCCHHHCCHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHH
IENGRPEVNGQTWVPHRPPRPEKSEGGVSFIMKSDFEPAGDQPQAIAELCAQAQAGERDQ
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
VLLGVTGSGKTFTMAKVIEQLQRPAIVLAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDY
EEEEECCCCCEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YQPEAYVPRTDTYIEKESSINEQIDRMRHAATRALLERDDVIIVASVSCIYGIGSVETYS
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCE
AMTFDIKVGERIDQRGLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRVS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCCEEEE
LFGDEVESIAEFDPLTGHKSGDMKSVRVYAASHYVTPRPTLIQAITGIKAELKMRLDELY
ECCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KMGRLLEAQRLEQRTRYDLEMMEATGSCAGIENYSRWLTGRKPGEPPPTLFEYVPDNSLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEE
FIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWEAMRPQTVHVSAT
EEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEC
PGTWEMEKTGGVFVEQVIRPTGLIDPPVEVRPARTQVDDLLGEVRAFAAKGYRTLVTVLT
CCCEEEHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
KRMAEDLTEYLHEHGIRVRYMHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPEC
HHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
GLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADRVTGSMERAMAETSRRREKQ
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
VAYNTAHGITPESVKKAIGDILNSVYERDHVQVDAGLAEEGAAFGHNLKAVMADLEKRMR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCHHHCCHHHHHHHHHHHHHH
AAAADLDFETAARLRDEIRRLEATELAVADDPLARQEAVEDKSGGFRGPRKYGKAANLPP
HHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCC
KEDAGKLLPRGRGAGRKPRSEPDDEGMGEEQAGYTAPVTRAHKPSLDDMGPGSDRAVPIT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC
EDTFRPGPRPDPGTKGYRKGGRRSKG
CCCCCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]