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The map label for this gene is gmhB [H]

Identifier: 154245896

GI number: 154245896

Start: 2209084

End: 2209641

Strand: Reverse

Name: gmhB [H]

Synonym: Xaut_1953

Alternate gene names: 154245896

Gene position: 2209641-2209084 (Counterclockwise)

Preceding gene: 154245898

Following gene: 154245889

Centisome position: 41.62

GC content: 69.35

Gene sequence:

>558_bases
ATGGTCGCGCCCGACAGCACGGGAGACGATGCTTTGAACGCCCCACGCACGCCACGCCCGGCGGTGTTTTTCGACCGGGA
CGGCGTCCTCAACGTGGATACGGGCTATGTCCACGCCCCGGAAGACTTCCGCTGGGTGGACGGGGCCCGGGAGGCGGTGC
GGCACTTCAATGCGCTGGGTCATCTCGTGTTCGTGGTGACCAACCAGTCCGGCGTCGCCCGGGGCTATTACGGGGAAGCC
GAGGTCGCGGCCCTGCATGGCTGGATGGCCGACGAGCTTGCAGCCATCGGCGCCCATGTGGACGACTGGCGCTATTGCCC
GTTCCATCCGGACGCGGCGGTGCCGGCCTATCGCGCGGTCCACCCCTGGCGCAAGCCGGCGCCGGGAATGATCCTCGACC
TCATGGACCACTGGCCGGTGGCGCGCGACCACAGCCTGCTCATCGGCGACCAGCCTTCCGACATGGAAGCCGCTGCGGCG
GCGGGCATCGCCGGCCATCTGTTTCCCGGCGGGGACCTGCTCGCCTTCGCCCGCGGACTGCGCTCCTCACAGGTTTGA

Upstream 100 bases:

>100_bases
CAGGGTTTTAATCTGGACGGCCGCTCCTTCTACGCCCGTCATCACGCTGTGGGAGGAAGCCTCCCCGGGATGGGGCTGGC
GGGGAACGCTCCCTTTTTCT

Downstream 100 bases:

>100_bases
GCGCCCCGCTCACGGCACCGGCGCATCGCACCCGGCAAGGCCGAGGCTGACACAGATGGCGCGGGCGAGGCTGCGATAGT
CGGGATTATCGGGACCCGTG

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVAPDSTGDDALNAPRTPRPAVFFDRDGVLNVDTGYVHAPEDFRWVDGAREAVRHFNALGHLVFVVTNQSGVARGYYGEA
EVAALHGWMADELAAIGAHVDDWRYCPFHPDAAVPAYRAVHPWRKPAPGMILDLMDHWPVARDHSLLIGDQPSDMEAAAA
AGIAGHLFPGGDLLAFARGLRSSQV

Sequences:

>Translated_185_residues
MVAPDSTGDDALNAPRTPRPAVFFDRDGVLNVDTGYVHAPEDFRWVDGAREAVRHFNALGHLVFVVTNQSGVARGYYGEA
EVAALHGWMADELAAIGAHVDDWRYCPFHPDAAVPAYRAVHPWRKPAPGMILDLMDHWPVARDHSLLIGDQPSDMEAAAA
AGIAGHLFPGGDLLAFARGLRSSQV
>Mature_185_residues
MVAPDSTGDDALNAPRTPRPAVFFDRDGVLNVDTGYVHAPEDFRWVDGAREAVRHFNALGHLVFVVTNQSGVARGYYGEA
EVAALHGWMADELAAIGAHVDDWRYCPFHPDAAVPAYRAVHPWRKPAPGMILDLMDHWPVARDHSLLIGDQPSDMEAAAA
AGIAGHLFPGGDLLAFARGLRSSQV

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=149, Percent_Identity=42.2818791946309, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20030; Mature: 20030

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPDSTGDDALNAPRTPRPAVFFDRDGVLNVDTGYVHAPEDFRWVDGAREAVRHFNALG
CCCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHC
HLVFVVTNQSGVARGYYGEAEVAALHGWMADELAAIGAHVDDWRYCPFHPDAAVPAYRAV
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHC
HPWRKPAPGMILDLMDHWPVARDHSLLIGDQPSDMEAAAAAGIAGHLFPGGDLLAFARGL
CCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
RSSQV
HHCCC
>Mature Secondary Structure
MVAPDSTGDDALNAPRTPRPAVFFDRDGVLNVDTGYVHAPEDFRWVDGAREAVRHFNALG
CCCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHC
HLVFVVTNQSGVARGYYGEAEVAALHGWMADELAAIGAHVDDWRYCPFHPDAAVPAYRAV
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHC
HPWRKPAPGMILDLMDHWPVARDHSLLIGDQPSDMEAAAAAGIAGHLFPGGDLLAFARGL
CCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
RSSQV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]