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The map label for this gene is yngE [H]

Identifier: 154245801

GI number: 154245801

Start: 2090191

End: 2091798

Strand: Reverse

Name: yngE [H]

Synonym: Xaut_1857

Alternate gene names: 154245801

Gene position: 2091798-2090191 (Counterclockwise)

Preceding gene: 154245802

Following gene: 154245800

Centisome position: 39.4

GC content: 67.23

Gene sequence:

>1608_bases
ATGGCGATCATTGAGGACGCGGTGGACCGCCGCTCCGACACCTTCCGCCGCAACAGTCAGGCCCTGGAAGCCTCCGTCGC
CGACTTGCGCACCACGGTGGAGCGCGTCGCCGAGGGCGGCGGGGAAGTGGCGCGCGAGCGACACCTGAAGCGCGGCAAGC
TCTTGCCGCGGGACCGCATCCGCACCCTGCTCGACACCGGCTCGCCCTTCCTCGAACTGTCGCAGCTTGCCGCCCACGGC
ATGTATGGCGACGAGGTGCCCGCCGCCGGCATCATCACCGGCATCGGCCGCGTCTCGGGCCGCGAATGCGTCATCGTCGC
CAACGACGCCACGGTGAAGGGCGGCACCTATTATCCCATCACCGTGAAGAAGCACCTGCGGGCCCAGGCCATCGCCCGCG
AAAACCATTTGCCCTGCATCTATCTGGTGGATTCCGGCGGCGCCAACCTGCCGAACCAGGACGAGGTCTTTCCCGACCGC
GAGCATTTCGGCCGGATCTTCTTCAACCAGGCCAACATGTCGGCGGAAGGCATCCCGCAGATCGCCGTGGTCATGGGCTC
GTGCACGGCGGGCGGCGCCTATGTGCCAGCCATGGCCGACCAGTCCATCATGGTGAAGAACCAGGCCACCATCTTCCTTG
GCGGCCCGCCGCTGGTAAAGGCCGCCACCGGCGAGGTGGTCACCGCCGAGGAGCTGGGCGGGGCGGACGTGCACACCCGC
ACCTCCGGCGTCGCCGACCACATGGCGGAGAACGACGCCCACGCGCTGGGCATCGCCCGCTCCATCGTCGCCGATCTCAA
CGCCACCAAGGCCCATTCCCTCGACATCCGCGAGCCCCGCGCGCCGCTCTACGACACGAAGGACATTTACGGCATCGTCT
CGGCCGACCCCAAGCAGCCCTTCGACGTGAGGCAGATCATCGCCCGCATCGTGGACGGGTCCGAATTCGACGAGTTCAAG
CCGCTTTATGGCCCCACGCTGGTGACCGGCTTTGCCCGCATCTTCGGCTATCCGGTGGGCATCATCGCCAACAACGGCAT
CCTGTTCTCCGAGAGCGCGCTGAAGGGCGCGCACTTCGTGGAATTGTGCTGCCAGCGCAATATTCCCCTCGTGTTCCTGC
AGAACATCACCGGCTTCATGGTGGGGCGGAAGTATGAGGCGGGCGGCATCGCCAAGGACGGGGCGAAGTTCGTCACCGCC
GTGTCGTGCGCCGCCGTGCCCAAGTTCACGGTGGTGATCGGCAATTCCTTCGGCGCCGGCAATTACGGCATGTGCGGGCG
CGCCTTCGATCCGCGGTTTTTGTGGATGTGGCCCAATGCCCGCATCTCGGTGATGGGCGGCGAGCAGGCGGCCGGCGTGC
TCGGCCAGGTGAAGCGCGACGGCATCGAGGCCCGTGGCGGCACCTGGTCGGCCGAGGAGGAAGAGGCGTTCAAGGCTCCC
ATCCGCACCCAGTACGAGGTGCAGGGCCATCCCTATTATTCCTCCGCGCGGCTGTGGGACGATGGCGTCATCGACCCCGC
CGACACCCGCATGGTGCTGGCCCTCGCCCTCTCCGCCGCGCTCAACGCCCCCGAGCAGGAGACGCGCTTCGGCGTGTTCC
GCATGTGA

Upstream 100 bases:

>100_bases
CCGCCCGCCCATTGAGGCGACGGGCGCGCGTCAGTCTCCGTTCGGTCAATGGCAGTTGGGCCGCTTTCATCGGCCCGTCT
TTTCGGGGGCGAGAGCGCTC

Downstream 100 bases:

>100_bases
TGGCGCGCGTTGACGGCCAAGTCCGGAGCACCATCCCATGAGCCTCAACACCACCGGCCTCATCACCACCGTCGAGGATG
GCGTCGCCGTCATCACCCTC

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MAIIEDAVDRRSDTFRRNSQALEASVADLRTTVERVAEGGGEVARERHLKRGKLLPRDRIRTLLDTGSPFLELSQLAAHG
MYGDEVPAAGIITGIGRVSGRECVIVANDATVKGGTYYPITVKKHLRAQAIARENHLPCIYLVDSGGANLPNQDEVFPDR
EHFGRIFFNQANMSAEGIPQIAVVMGSCTAGGAYVPAMADQSIMVKNQATIFLGGPPLVKAATGEVVTAEELGGADVHTR
TSGVADHMAENDAHALGIARSIVADLNATKAHSLDIREPRAPLYDTKDIYGIVSADPKQPFDVRQIIARIVDGSEFDEFK
PLYGPTLVTGFARIFGYPVGIIANNGILFSESALKGAHFVELCCQRNIPLVFLQNITGFMVGRKYEAGGIAKDGAKFVTA
VSCAAVPKFTVVIGNSFGAGNYGMCGRAFDPRFLWMWPNARISVMGGEQAAGVLGQVKRDGIEARGGTWSAEEEEAFKAP
IRTQYEVQGHPYYSSARLWDDGVIDPADTRMVLALALSAALNAPEQETRFGVFRM

Sequences:

>Translated_535_residues
MAIIEDAVDRRSDTFRRNSQALEASVADLRTTVERVAEGGGEVARERHLKRGKLLPRDRIRTLLDTGSPFLELSQLAAHG
MYGDEVPAAGIITGIGRVSGRECVIVANDATVKGGTYYPITVKKHLRAQAIARENHLPCIYLVDSGGANLPNQDEVFPDR
EHFGRIFFNQANMSAEGIPQIAVVMGSCTAGGAYVPAMADQSIMVKNQATIFLGGPPLVKAATGEVVTAEELGGADVHTR
TSGVADHMAENDAHALGIARSIVADLNATKAHSLDIREPRAPLYDTKDIYGIVSADPKQPFDVRQIIARIVDGSEFDEFK
PLYGPTLVTGFARIFGYPVGIIANNGILFSESALKGAHFVELCCQRNIPLVFLQNITGFMVGRKYEAGGIAKDGAKFVTA
VSCAAVPKFTVVIGNSFGAGNYGMCGRAFDPRFLWMWPNARISVMGGEQAAGVLGQVKRDGIEARGGTWSAEEEEAFKAP
IRTQYEVQGHPYYSSARLWDDGVIDPADTRMVLALALSAALNAPEQETRFGVFRM
>Mature_534_residues
AIIEDAVDRRSDTFRRNSQALEASVADLRTTVERVAEGGGEVARERHLKRGKLLPRDRIRTLLDTGSPFLELSQLAAHGM
YGDEVPAAGIITGIGRVSGRECVIVANDATVKGGTYYPITVKKHLRAQAIARENHLPCIYLVDSGGANLPNQDEVFPDRE
HFGRIFFNQANMSAEGIPQIAVVMGSCTAGGAYVPAMADQSIMVKNQATIFLGGPPLVKAATGEVVTAEELGGADVHTRT
SGVADHMAENDAHALGIARSIVADLNATKAHSLDIREPRAPLYDTKDIYGIVSADPKQPFDVRQIIARIVDGSEFDEFKP
LYGPTLVTGFARIFGYPVGIIANNGILFSESALKGAHFVELCCQRNIPLVFLQNITGFMVGRKYEAGGIAKDGAKFVTAV
SCAAVPKFTVVIGNSFGAGNYGMCGRAFDPRFLWMWPNARISVMGGEQAAGVLGQVKRDGIEARGGTWSAEEEEAFKAPI
RTQYEVQGHPYYSSARLWDDGVIDPADTRMVLALALSAALNAPEQETRFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=528, Percent_Identity=66.0984848484848, Blast_Score=711, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=493, Percent_Identity=34.4827586206897, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI295821216, Length=506, Percent_Identity=33.596837944664, Blast_Score=225, Evalue=9e-59,
Organism=Homo sapiens, GI310133460, Length=138, Percent_Identity=60.8695652173913, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17552936, Length=535, Percent_Identity=62.9906542056075, Blast_Score=714, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=495, Percent_Identity=34.1414141414141, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI25147359, Length=495, Percent_Identity=34.1414141414141, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586065, Length=553, Percent_Identity=64.1952983725136, Blast_Score=741, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 57675; Mature: 57544

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIEDAVDRRSDTFRRNSQALEASVADLRTTVERVAEGGGEVARERHLKRGKLLPRDRI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
RTLLDTGSPFLELSQLAAHGMYGDEVPAAGIITGIGRVSGRECVIVANDATVKGGTYYPI
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEECCCEEEEE
TVKKHLRAQAIARENHLPCIYLVDSGGANLPNQDEVFPDREHFGRIFFNQANMSAEGIPQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCE
IAVVMGSCTAGGAYVPAMADQSIMVKNQATIFLGGPPLVKAATGEVVTAEELGGADVHTR
EEEEEECCCCCCEECCCCCCCEEEEECCEEEEECCCCEEEECCCCEEEHHHCCCCCCCCC
TSGVADHMAENDAHALGIARSIVADLNATKAHSLDIREPRAPLYDTKDIYGIVSADPKQP
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
FDVRQIIARIVDGSEFDEFKPLYGPTLVTGFARIFGYPVGIIANNGILFSESALKGAHFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEECHHHCCHHHH
ELCCQRNIPLVFLQNITGFMVGRKYEAGGIAKDGAKFVTAVSCAAVPKFTVVIGNSFGAG
HHHHHCCCCEEEECCCCHHHCCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCC
NYGMCGRAFDPRFLWMWPNARISVMGGEQAAGVLGQVKRDGIEARGGTWSAEEEEAFKAP
CCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
IRTQYEVQGHPYYSSARLWDDGVIDPADTRMVLALALSAALNAPEQETRFGVFRM
CCCEEEECCCCEECCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure 
AIIEDAVDRRSDTFRRNSQALEASVADLRTTVERVAEGGGEVARERHLKRGKLLPRDRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
RTLLDTGSPFLELSQLAAHGMYGDEVPAAGIITGIGRVSGRECVIVANDATVKGGTYYPI
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEECCCEEEEE
TVKKHLRAQAIARENHLPCIYLVDSGGANLPNQDEVFPDREHFGRIFFNQANMSAEGIPQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCE
IAVVMGSCTAGGAYVPAMADQSIMVKNQATIFLGGPPLVKAATGEVVTAEELGGADVHTR
EEEEEECCCCCCEECCCCCCCEEEEECCEEEEECCCCEEEECCCCEEEHHHCCCCCCCCC
TSGVADHMAENDAHALGIARSIVADLNATKAHSLDIREPRAPLYDTKDIYGIVSADPKQP
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
FDVRQIIARIVDGSEFDEFKPLYGPTLVTGFARIFGYPVGIIANNGILFSESALKGAHFV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEECHHHCCHHHH
ELCCQRNIPLVFLQNITGFMVGRKYEAGGIAKDGAKFVTAVSCAAVPKFTVVIGNSFGAG
HHHHHCCCCEEEECCCCHHHCCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCC
NYGMCGRAFDPRFLWMWPNARISVMGGEQAAGVLGQVKRDGIEARGGTWSAEEEEAFKAP
CCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
IRTQYEVQGHPYYSSARLWDDGVIDPADTRMVLALALSAALNAPEQETRFGVFRM
CCCEEEECCCCEECCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]