| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
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The map label for this gene is murE [H]
Identifier: 154245793
GI number: 154245793
Start: 2080362
End: 2081867
Strand: Reverse
Name: murE [H]
Synonym: Xaut_1849
Alternate gene names: 154245793
Gene position: 2081867-2080362 (Counterclockwise)
Preceding gene: 154245794
Following gene: 154245792
Centisome position: 39.21
GC content: 70.32
Gene sequence:
>1506_bases GTGGATGCCAAAAGAGGTCCGATGACCAGCCTTTCCCTCGGACAGCTCCTCGACGGCCACGCCCGTATCCTATCCGCCGG CGCGGGCGACGAGCCCGTCTTCGGCCTCTCCGCCGACAGCCGCAGGATCAATCCCGGCGACCTCTTCGTCGCCATTCCCG GCACCCATGCGGACGGCAGCCGCTTCATCGCCGATGCGGTGGCGCGCGGCGCTTCGGCGGTGCTGATGGAGCCCGCCGCG CCCCGGCCGGTGCTGCCGCCCCATGTGGCGCTTGCCTTCTCCCTCGACGTGCGGCACTCCCTGTCGCTGGCGGCGGCGCG CTTCTATCCGCGCCAGCCGGCCACCATCGCGGCGGTGACCGGGACGGCGGGCAAGACCTCGGTCGCCTTCTTCCTGCGGC AGATCTGGGAGCGGCTCGGCCACAAGGCGGCTTATTTGGGCACCATTGGCCTGGTGGCGCCGGACGGCTCCACCTATGGC AGCCTCACCACCCCCGATCCGGTGGAGCTGCACGCCACCCTCGACCGCCTCGCCGGCGAGGGTGTCACCCACATGGCGCT GGAGGCCTCGTCCCACGGGCTGGACCAGAAGCGGCTCGACGGTGTGCACTTCACTGCCGGCGGCTTCACCAATCTCGGCC GCGACCATCTGGACTACCACCCCACCATCGACGCCTATTTCCGGGCCAAGCTCCGCCTCTTCACCCAGGTGATGCCGGAT GACGCCACCGCCGTGGCGGTGACCGGCGCGCCATTTGCTGCCAATGCGCTGGCCTGGGCTGAGACGCGCGGCCTGAAGCT GCTGCCCATCGGCGAGGGGCAGGCAACCGGTCTCGACATCTTCGGCACCACGGGGTCCGGCACCGGGCAGAAGGTGATGT TCGCCGACGGCAGTCATGCCATCGTGCCGCTGGTGGGCCGCTTCCAGCTCGACAACGCTTTGCTCGCCGCCGGCCTTGCC ATTGCCTGCGGGGCGGAGCGGCCGGCGGCGCTGGAGGCCCTCGCATATCTGACCGGCGTGCCCGGCCGGCTGGAGCGCAT CGGCGACGATCCGCGCCGGCCCGTGTTCGTGGACTACGCCCACAAGCCCGAGGCGCTGGCCACCGTGCTCGACACCCTGC GCGCGGCGGTGCCGGGGCGGCTCATGGTGGTGTTCGGCTGCGGCGGCGACCGGGACAAGGGCAAGCGCCCCCTCATGGGC GCCATCGCCGCCTCCAAGGCGGACGTGGTGATCGTCACCGACGACAATCCCCGCAGCGAGGACCCCGCCGCCATCCGCGC CGAAATCCTGGAAGGTGCCCACGGCGCCAGGGAAATCGGCGACCGGGCGGAGGCCATCAAGGCGGCCGTGGCGCTGCTTC AGCCTGGGGATGCGCTCATTGTTGCCGGCAAGGGTCACGAAACCGGCCAAATCATCGGCGACCGGACATATCCGTTCTCG GACGCGGCGGAAGTCCGTGCCGCTCTTGAGTCGGGTTCCGGGAGTCCGTCTCTCAATTTGGGGTAA
Upstream 100 bases:
>100_bases GTCGGTGAGAAACGCGCCCCGGCTCTTGGAATCGTCCTTGGCCGCACATTGATACCACCCGCGTGACGCGACCTCAGGTC GAGGGTGACAACCGGCGCGG
Downstream 100 bases:
>100_bases GAGCACGCATCATCCCATCGTCGCGCGGAGCGGAACGATGGGCGCGGGCTTCGCAGGAGGTAGCGGCATGAACATGAGCG CTGGCATGAGCGGTCGGGTC
Product: UDP-N-acetylmuramyl-tripeptide synthetase
Products: NA
Alternate protein names: Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase [H]
Number of amino acids: Translated: 501; Mature: 501
Protein sequence:
>501_residues MDAKRGPMTSLSLGQLLDGHARILSAGAGDEPVFGLSADSRRINPGDLFVAIPGTHADGSRFIADAVARGASAVLMEPAA PRPVLPPHVALAFSLDVRHSLSLAAARFYPRQPATIAAVTGTAGKTSVAFFLRQIWERLGHKAAYLGTIGLVAPDGSTYG SLTTPDPVELHATLDRLAGEGVTHMALEASSHGLDQKRLDGVHFTAGGFTNLGRDHLDYHPTIDAYFRAKLRLFTQVMPD DATAVAVTGAPFAANALAWAETRGLKLLPIGEGQATGLDIFGTTGSGTGQKVMFADGSHAIVPLVGRFQLDNALLAAGLA IACGAERPAALEALAYLTGVPGRLERIGDDPRRPVFVDYAHKPEALATVLDTLRAAVPGRLMVVFGCGGDRDKGKRPLMG AIAASKADVVIVTDDNPRSEDPAAIRAEILEGAHGAREIGDRAEAIKAAVALLQPGDALIVAGKGHETGQIIGDRTYPFS DAAEVRAALESGSGSPSLNLG
Sequences:
>Translated_501_residues MDAKRGPMTSLSLGQLLDGHARILSAGAGDEPVFGLSADSRRINPGDLFVAIPGTHADGSRFIADAVARGASAVLMEPAA PRPVLPPHVALAFSLDVRHSLSLAAARFYPRQPATIAAVTGTAGKTSVAFFLRQIWERLGHKAAYLGTIGLVAPDGSTYG SLTTPDPVELHATLDRLAGEGVTHMALEASSHGLDQKRLDGVHFTAGGFTNLGRDHLDYHPTIDAYFRAKLRLFTQVMPD DATAVAVTGAPFAANALAWAETRGLKLLPIGEGQATGLDIFGTTGSGTGQKVMFADGSHAIVPLVGRFQLDNALLAAGLA IACGAERPAALEALAYLTGVPGRLERIGDDPRRPVFVDYAHKPEALATVLDTLRAAVPGRLMVVFGCGGDRDKGKRPLMG AIAASKADVVIVTDDNPRSEDPAAIRAEILEGAHGAREIGDRAEAIKAAVALLQPGDALIVAGKGHETGQIIGDRTYPFS DAAEVRAALESGSGSPSLNLG >Mature_501_residues MDAKRGPMTSLSLGQLLDGHARILSAGAGDEPVFGLSADSRRINPGDLFVAIPGTHADGSRFIADAVARGASAVLMEPAA PRPVLPPHVALAFSLDVRHSLSLAAARFYPRQPATIAAVTGTAGKTSVAFFLRQIWERLGHKAAYLGTIGLVAPDGSTYG SLTTPDPVELHATLDRLAGEGVTHMALEASSHGLDQKRLDGVHFTAGGFTNLGRDHLDYHPTIDAYFRAKLRLFTQVMPD DATAVAVTGAPFAANALAWAETRGLKLLPIGEGQATGLDIFGTTGSGTGQKVMFADGSHAIVPLVGRFQLDNALLAAGLA IACGAERPAALEALAYLTGVPGRLERIGDDPRRPVFVDYAHKPEALATVLDTLRAAVPGRLMVVFGCGGDRDKGKRPLMG AIAASKADVVIVTDDNPRSEDPAAIRAEILEGAHGAREIGDRAEAIKAAVALLQPGDALIVAGKGHETGQIIGDRTYPFS DAAEVRAALESGSGSPSLNLG
Specific function: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan [H]
COG id: COG0769
COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family. MurE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786273, Length=481, Percent_Identity=38.2536382536383, Blast_Score=225, Evalue=5e-60,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005761 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.13 [H]
Molecular weight: Translated: 52026; Mature: 52026
Theoretical pI: Translated: 6.46; Mature: 6.46
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDAKRGPMTSLSLGQLLDGHARILSAGAGDEPVFGLSADSRRINPGDLFVAIPGTHADGS CCCCCCCCCCCHHHHHHCCCHHEEECCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCH RFIADAVARGASAVLMEPAAPRPVLPPHVALAFSLDVRHSLSLAAARFYPRQPATIAAVT HHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEE GTAGKTSVAFFLRQIWERLGHKAAYLGTIGLVAPDGSTYGSLTTPDPVELHATLDRLAGE CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC GVTHMALEASSHGLDQKRLDGVHFTAGGFTNLGRDHLDYHPTIDAYFRAKLRLFTQVMPD CCEEEEEECCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC DATAVAVTGAPFAANALAWAETRGLKLLPIGEGQATGLDIFGTTGSGTGQKVMFADGSHA CCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCE IVPLVGRFQLDNALLAAGLAIACGAERPAALEALAYLTGVPGRLERIGDDPRRPVFVDYA EEEEEEEEECCHHHHHHCHHEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCEEEECC HKPEALATVLDTLRAAVPGRLMVVFGCGGDRDKGKRPLMGAIAASKADVVIVTDDNPRSE CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCC DPAAIRAEILEGAHGAREIGDRAEAIKAAVALLQPGDALIVAGKGHETGQIIGDRTYPFS CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCCCCC DAAEVRAALESGSGSPSLNLG CHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MDAKRGPMTSLSLGQLLDGHARILSAGAGDEPVFGLSADSRRINPGDLFVAIPGTHADGS CCCCCCCCCCCHHHHHHCCCHHEEECCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCH RFIADAVARGASAVLMEPAAPRPVLPPHVALAFSLDVRHSLSLAAARFYPRQPATIAAVT HHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEE GTAGKTSVAFFLRQIWERLGHKAAYLGTIGLVAPDGSTYGSLTTPDPVELHATLDRLAGE CCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC GVTHMALEASSHGLDQKRLDGVHFTAGGFTNLGRDHLDYHPTIDAYFRAKLRLFTQVMPD CCEEEEEECCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC DATAVAVTGAPFAANALAWAETRGLKLLPIGEGQATGLDIFGTTGSGTGQKVMFADGSHA CCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCE IVPLVGRFQLDNALLAAGLAIACGAERPAALEALAYLTGVPGRLERIGDDPRRPVFVDYA EEEEEEEEECCHHHHHHCHHEEECCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCEEEECC HKPEALATVLDTLRAAVPGRLMVVFGCGGDRDKGKRPLMGAIAASKADVVIVTDDNPRSE CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCC DPAAIRAEILEGAHGAREIGDRAEAIKAAVALLQPGDALIVAGKGHETGQIIGDRTYPFS CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCCCCC DAAEVRAALESGSGSPSLNLG CHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11481430 [H]