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The map label for this gene is fadE [H]

Identifier: 154245646

GI number: 154245646

Start: 1916570

End: 1917760

Strand: Reverse

Name: fadE [H]

Synonym: Xaut_1702

Alternate gene names: 154245646

Gene position: 1917760-1916570 (Counterclockwise)

Preceding gene: 154245647

Following gene: 154245645

Centisome position: 36.12

GC content: 67.84

Gene sequence:

>1191_bases
ATGGACACCTTCTTCAGCGATGCGGAACAGGCGTTTCGCGCCGAGGTACGGGCCTTCATCCGCGCCAATCTGCCCGCGGA
CCTTGCCGCCAGGGTCCGGGCCGGCATCCATCTCTCTCGCGCCGACATGGCCCGCTGGAACGCCATTCTCGACGCCAAGG
GCTGGGCCGCGCACCACTGGCCGCAGACCTATGGCGGGCCGGGCTGGACCCCCATCCAGCGCTTCCTGTTCGAGGCCGAA
TGCGCGGACGCCGATGCCCCGCCGCTGAGCGTGTTCGGCGTCTATCTCGTCGGCCCCACCCTCTACACCTTCGGCTCGCA
GGCGCAGAAAGAGGCCTACCTGCCGGGCATCCGCTCCGGCGCGACCTTCTGGTGCCAGGGCTACAGCGAGCCCAATGCAG
GCTCGGATCTTGCCAGCCTCAAGACCACGGCGCGCAAGGTGGAGGGCGGCTATGTCATCGACGGCGCCAAGGCCTGGACC
ACCGAAGGCCATTTCGCGGACTACATGATCTGCCTCGCGCGGACCAATCCGCAGGCGAAGCCCCAGGCCGGACTGTCTCT
GTTCATCGTCGACATGACGGCCAAGGGCGTCTCGCTGCAGCCGGTCATCACCATCGACGGTGCCCATTCGGTGAACACCA
CCTTCCTCGACGCCGTCTTCGTGCCCGACGACGCCCTCATCGGCGAGATCGACAAGGGCTGGACCTATGCCAAGTTCCTG
CTCAGCCACGAGCGCACCAACAACGCCCAGGTCCACCGCTCGCGGCGTGAGTTCACTCGGCTGAAGGAGCTGGCGCGGCA
GATGAGTGGGCCGGCGGGCGGCAGCGTCCTCGACGATCCGGTTTTCCAGCGGCGCTTCGCGGCCCTCGACGTGGAACTCA
GCGCCCTGGAGGTCACGGTCCTGCGCGTACTCGCCGACCAGACCGACGGCCGCGAGCCGGGGCCGGAAGCCTCCATCCTC
AAGGTCATCGGCTCCGAACTGCAGCAGCGCATCAGCGAGCTGGCCATGGAGGTGCTCGGCGAAGAGGGCATCCGGCAGAG
CCATGGTGAGGTGGATGGGGAAGCGGGGGCGGCCGCCACGCAGGCGGCGGGCTGGGCCGAGCGCCACCTCTTCCGCCGCG
TGGTGACCATCTATGCCGGAGCCAACGAGATCCAGAAGACCATCATTGCCCGCACCGTGCTGGGGATGTGA

Upstream 100 bases:

>100_bases
CGGGCTCAGCCTGCCGCTGGCGGACGCGGGCGAGGCCCATCGCCGCCTTGAAGCCGGCACCACCACCGGCTCGCTCATTC
TGATCCCCTGAGAGGCCGCC

Downstream 100 bases:

>100_bases
GGAGCCATGCGCAGATCCGAACACCGACGCGAGGAGGATGCGCTGCTGCGCGACAGCGCGCGGCGCTTCCTTGAAGACAC
TTACGCCTGGTCGCCTACCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MDTFFSDAEQAFRAEVRAFIRANLPADLAARVRAGIHLSRADMARWNAILDAKGWAAHHWPQTYGGPGWTPIQRFLFEAE
CADADAPPLSVFGVYLVGPTLYTFGSQAQKEAYLPGIRSGATFWCQGYSEPNAGSDLASLKTTARKVEGGYVIDGAKAWT
TEGHFADYMICLARTNPQAKPQAGLSLFIVDMTAKGVSLQPVITIDGAHSVNTTFLDAVFVPDDALIGEIDKGWTYAKFL
LSHERTNNAQVHRSRREFTRLKELARQMSGPAGGSVLDDPVFQRRFAALDVELSALEVTVLRVLADQTDGREPGPEASIL
KVIGSELQQRISELAMEVLGEEGIRQSHGEVDGEAGAAATQAAGWAERHLFRRVVTIYAGANEIQKTIIARTVLGM

Sequences:

>Translated_396_residues
MDTFFSDAEQAFRAEVRAFIRANLPADLAARVRAGIHLSRADMARWNAILDAKGWAAHHWPQTYGGPGWTPIQRFLFEAE
CADADAPPLSVFGVYLVGPTLYTFGSQAQKEAYLPGIRSGATFWCQGYSEPNAGSDLASLKTTARKVEGGYVIDGAKAWT
TEGHFADYMICLARTNPQAKPQAGLSLFIVDMTAKGVSLQPVITIDGAHSVNTTFLDAVFVPDDALIGEIDKGWTYAKFL
LSHERTNNAQVHRSRREFTRLKELARQMSGPAGGSVLDDPVFQRRFAALDVELSALEVTVLRVLADQTDGREPGPEASIL
KVIGSELQQRISELAMEVLGEEGIRQSHGEVDGEAGAAATQAAGWAERHLFRRVVTIYAGANEIQKTIIARTVLGM
>Mature_396_residues
MDTFFSDAEQAFRAEVRAFIRANLPADLAARVRAGIHLSRADMARWNAILDAKGWAAHHWPQTYGGPGWTPIQRFLFEAE
CADADAPPLSVFGVYLVGPTLYTFGSQAQKEAYLPGIRSGATFWCQGYSEPNAGSDLASLKTTARKVEGGYVIDGAKAWT
TEGHFADYMICLARTNPQAKPQAGLSLFIVDMTAKGVSLQPVITIDGAHSVNTTFLDAVFVPDDALIGEIDKGWTYAKFL
LSHERTNNAQVHRSRREFTRLKELARQMSGPAGGSVLDDPVFQRRFAALDVELSALEVTVLRVLADQTDGREPGPEASIL
KVIGSELQQRISELAMEVLGEEGIRQSHGEVDGEAGAAATQAAGWAERHLFRRVVTIYAGANEIQKTIIARTVLGM

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=318, Percent_Identity=26.7295597484277, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=351, Percent_Identity=28.4900284900285, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI76496475, Length=302, Percent_Identity=26.4900662251656, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4557235, Length=302, Percent_Identity=26.4900662251656, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI226958412, Length=178, Percent_Identity=33.7078651685393, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226958414, Length=178, Percent_Identity=33.7078651685393, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4557231, Length=400, Percent_Identity=23.25, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI187960098, Length=400, Percent_Identity=23.25, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4501859, Length=415, Percent_Identity=23.1325301204819, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4503943, Length=346, Percent_Identity=24.2774566473988, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI21361497, Length=363, Percent_Identity=24.5179063360882, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=346, Percent_Identity=23.4104046242775, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786223, Length=299, Percent_Identity=23.4113712374582, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=348, Percent_Identity=27.8735632183908, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=346, Percent_Identity=25.7225433526012, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=189, Percent_Identity=32.8042328042328, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=344, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=252, Percent_Identity=29.3650793650794, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=358, Percent_Identity=24.3016759776536, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=185, Percent_Identity=31.3513513513514, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=303, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=24.7863247863248, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=413, Percent_Identity=24.2130750605327, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356377, Length=406, Percent_Identity=28.3251231527094, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24666513, Length=342, Percent_Identity=24.8538011695906, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363737, Length=306, Percent_Identity=25.1633986928105, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355753, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920834, Length=416, Percent_Identity=23.5576923076923, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43122; Mature: 43122

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTFFSDAEQAFRAEVRAFIRANLPADLAARVRAGIHLSRADMARWNAILDAKGWAAHHW
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECHHHHHHHHHHCCCCCCCCCCC
PQTYGGPGWTPIQRFLFEAECADADAPPLSVFGVYLVGPTLYTFGSQAQKEAYLPGIRSG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCC
ATFWCQGYSEPNAGSDLASLKTTARKVEGGYVIDGAKAWTTEGHFADYMICLARTNPQAK
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEECCCCCHHEEEEEEECCCCCCC
PQAGLSLFIVDMTAKGVSLQPVITIDGAHSVNTTFLDAVFVPDDALIGEIDKGWTYAKFL
CCCCCEEEEEEEECCCCEECEEEEECCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHH
LSHERTNNAQVHRSRREFTRLKELARQMSGPAGGSVLDDPVFQRRFAALDVELSALEVTV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCEEHHHHHHHH
LRVLADQTDGREPGPEASILKVIGSELQQRISELAMEVLGEEGIRQSHGEVDGEAGAAAT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
QAAGWAERHLFRRVVTIYAGANEIQKTIIARTVLGM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTFFSDAEQAFRAEVRAFIRANLPADLAARVRAGIHLSRADMARWNAILDAKGWAAHHW
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECHHHHHHHHHHCCCCCCCCCCC
PQTYGGPGWTPIQRFLFEAECADADAPPLSVFGVYLVGPTLYTFGSQAQKEAYLPGIRSG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCC
ATFWCQGYSEPNAGSDLASLKTTARKVEGGYVIDGAKAWTTEGHFADYMICLARTNPQAK
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEECCCCCHHEEEEEEECCCCCCC
PQAGLSLFIVDMTAKGVSLQPVITIDGAHSVNTTFLDAVFVPDDALIGEIDKGWTYAKFL
CCCCCEEEEEEEECCCCEECEEEEECCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHH
LSHERTNNAQVHRSRREFTRLKELARQMSGPAGGSVLDDPVFQRRFAALDVELSALEVTV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCEEHHHHHHHH
LRVLADQTDGREPGPEASILKVIGSELQQRISELAMEVLGEEGIRQSHGEVDGEAGAAAT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
QAAGWAERHLFRRVVTIYAGANEIQKTIIARTVLGM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]