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The map label for this gene is yngJ [H]

Identifier: 154245645

GI number: 154245645

Start: 1915499

End: 1916563

Strand: Reverse

Name: yngJ [H]

Synonym: Xaut_1701

Alternate gene names: 154245645

Gene position: 1916563-1915499 (Counterclockwise)

Preceding gene: 154245646

Following gene: 154245644

Centisome position: 36.1

GC content: 71.92

Gene sequence:

>1065_bases
ATGCGCAGATCCGAACACCGACGCGAGGAGGATGCGCTGCTGCGCGACAGCGCGCGGCGCTTCCTTGAAGACACTTACGC
CTGGTCGCCTACCCGCGCGTGCGATCCGAAGGCGCGCTGGCGCGCCATGGCGGAGCTGGGCTGGTTTGCTCTCGGCCTGC
CGGAGGCGCTGGGCGGCATCGGCGGCGATGCCGCCCAATGTATGGTGATCCTGGAGGAGGCCGGCCGCGTGCTGGACGAG
GCGCCGCTGCTGGCGAGCCTCCTTCTGGCCGCGCCCGTGCTGGCGGCCCTCCCACTTGAGGTGGCGCAACCTCTGGCGGA
TGGCCTTCAGGCGGGCAGCGTGCGCTTGGCCTATGTCCCCGATGCCGGCCTGCGGCTGGGCGAGGGCGGGACATTGTTGT
CCGGGCGTAGCCGGCTGGCCCTCGGCATCGACCTTGCCACCCACTGGATCGTGCCCGTGGGCTCCGGCTCGGCGAATGGC
GCGGCGGTGCTGCTGCTGCCGGCATCGGCCGCGGCGGCGCTGGACCGGACATTGCTGATGGACGGCCGAACCGCCGCCGT
GCTCAGCTTCGCCAACCTGCCGGTGGCGCCGGACGCCATCGTGGCGCGGGGCGAAGCGGCCTTCGAGCTTGCCGCGCTCC
TCGCCGATGCGGCGGCGGTGGGGGCCTCCGCGGAAGCCCTCGGCGCGGCCGATGCGGGGCTCGCTCTCACCGTGTCCTAT
CTCAAGGACCGCACCCAGTTCGGCGCGCCTCTGGCGTCGTTCCAGGCGGTGCAGCACATGATGGCCGAGAGCTTCTGTGA
GATCGCGCAGATGCGTTCCCTGCTGATGTGGGCGGCGGATGCCCTTGCCGGGCCGGCCGGAGAGCGCGCGCGGGCGGCGT
CAGCGCTCAAGGCCTATGCCGGCATGCAGGGCCTCAAGGCGGTGGCCCGGTGCATCCAGGTCAGCGGCGGCATCGGCGTC
ACGCAGGAATACCGCATCGGCCACGTCTACAAACGCCTCCAGACCCATGCGGCGCTGTTCGGCTCCACGCAGGAGCATCT
CGCCCGCTTCGGCGTCGCCGCGTGA

Upstream 100 bases:

>100_bases
CGAGCGCCACCTCTTCCGCCGCGTGGTGACCATCTATGCCGGAGCCAACGAGATCCAGAAGACCATCATTGCCCGCACCG
TGCTGGGGATGTGAGGAGCC

Downstream 100 bases:

>100_bases
AGTCTTCAACACACCTTCAAGACGAAGAAAGACCTTTCTCCCATGAAGCGGATCCCCCTGGAAGAGCGCTACGAGACCCT
GAAGATCGAGCGCAAGGGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRRSEHRREEDALLRDSARRFLEDTYAWSPTRACDPKARWRAMAELGWFALGLPEALGGIGGDAAQCMVILEEAGRVLDE
APLLASLLLAAPVLAALPLEVAQPLADGLQAGSVRLAYVPDAGLRLGEGGTLLSGRSRLALGIDLATHWIVPVGSGSANG
AAVLLLPASAAAALDRTLLMDGRTAAVLSFANLPVAPDAIVARGEAAFELAALLADAAAVGASAEALGAADAGLALTVSY
LKDRTQFGAPLASFQAVQHMMAESFCEIAQMRSLLMWAADALAGPAGERARAASALKAYAGMQGLKAVARCIQVSGGIGV
TQEYRIGHVYKRLQTHAALFGSTQEHLARFGVAA

Sequences:

>Translated_354_residues
MRRSEHRREEDALLRDSARRFLEDTYAWSPTRACDPKARWRAMAELGWFALGLPEALGGIGGDAAQCMVILEEAGRVLDE
APLLASLLLAAPVLAALPLEVAQPLADGLQAGSVRLAYVPDAGLRLGEGGTLLSGRSRLALGIDLATHWIVPVGSGSANG
AAVLLLPASAAAALDRTLLMDGRTAAVLSFANLPVAPDAIVARGEAAFELAALLADAAAVGASAEALGAADAGLALTVSY
LKDRTQFGAPLASFQAVQHMMAESFCEIAQMRSLLMWAADALAGPAGERARAASALKAYAGMQGLKAVARCIQVSGGIGV
TQEYRIGHVYKRLQTHAALFGSTQEHLARFGVAA
>Mature_354_residues
MRRSEHRREEDALLRDSARRFLEDTYAWSPTRACDPKARWRAMAELGWFALGLPEALGGIGGDAAQCMVILEEAGRVLDE
APLLASLLLAAPVLAALPLEVAQPLADGLQAGSVRLAYVPDAGLRLGEGGTLLSGRSRLALGIDLATHWIVPVGSGSANG
AAVLLLPASAAAALDRTLLMDGRTAAVLSFANLPVAPDAIVARGEAAFELAALLADAAAVGASAEALGAADAGLALTVSY
LKDRTQFGAPLASFQAVQHMMAESFCEIAQMRSLLMWAADALAGPAGERARAASALKAYAGMQGLKAVARCIQVSGGIGV
TQEYRIGHVYKRLQTHAALFGSTQEHLARFGVAA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=25.5681818181818, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4501859, Length=153, Percent_Identity=28.7581699346405, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=24.4565217391304, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=23.3062330623306, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=360, Percent_Identity=24.1666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666513, Length=161, Percent_Identity=27.3291925465839, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 36743; Mature: 36743

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSEHRREEDALLRDSARRFLEDTYAWSPTRACDPKARWRAMAELGWFALGLPEALGGI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCC
GGDAAQCMVILEEAGRVLDEAPLLASLLLAAPVLAALPLEVAQPLADGLQAGSVRLAYVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DAGLRLGEGGTLLSGRSRLALGIDLATHWIVPVGSGSANGAAVLLLPASAAAALDRTLLM
CCCCEECCCCCEECCCCCEEEEEEEHHEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHC
DGRTAAVLSFANLPVAPDAIVARGEAAFELAALLADAAAVGASAEALGAADAGLALTVSY
CCCHHHHHEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHH
LKDRTQFGAPLASFQAVQHMMAESFCEIAQMRSLLMWAADALAGPAGERARAASALKAYA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GMQGLKAVARCIQVSGGIGVTQEYRIGHVYKRLQTHAALFGSTQEHLARFGVAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure
MRRSEHRREEDALLRDSARRFLEDTYAWSPTRACDPKARWRAMAELGWFALGLPEALGGI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCC
GGDAAQCMVILEEAGRVLDEAPLLASLLLAAPVLAALPLEVAQPLADGLQAGSVRLAYVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
DAGLRLGEGGTLLSGRSRLALGIDLATHWIVPVGSGSANGAAVLLLPASAAAALDRTLLM
CCCCEECCCCCEECCCCCEEEEEEEHHEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHC
DGRTAAVLSFANLPVAPDAIVARGEAAFELAALLADAAAVGASAEALGAADAGLALTVSY
CCCHHHHHEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHH
LKDRTQFGAPLASFQAVQHMMAESFCEIAQMRSLLMWAADALAGPAGERARAASALKAYA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GMQGLKAVARCIQVSGGIGVTQEYRIGHVYKRLQTHAALFGSTQEHLARFGVAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]