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The map label for this gene is lldR [H]

Identifier: 154245643

GI number: 154245643

Start: 1913082

End: 1914623

Strand: Direct

Name: lldR [H]

Synonym: Xaut_1699

Alternate gene names: 154245643

Gene position: 1913082-1914623 (Clockwise)

Preceding gene: 154245641

Following gene: 154245648

Centisome position: 36.04

GC content: 70.3

Gene sequence:

>1542_bases
ATGTCCGATGCCGCATTGGACCTGAAGCTGTGCCTTCTTCGGGGTGAGACGCCAAGCCCGCTCGACCTCAACAGCTTTGC
CGGCGCCGACCGCATCCGCCTGCGGACCCAAACCAAGTCGGCGGTCTCCGATCGCCTCGCCGTGCGCCTCCTGACCCTCA
TGGCATCGGGACGGCTGCCGCCGGGCGCCCGCCTGCCGCCGGAGCGGCAGATCGCCGAAACCGTGTCGGTGAGCCGGGTG
TGCGTGCGCACCGCGCTGGAGCGCCTGAAGAGCGCCGGCTACCTGCGCTCGATCCAGGGCTCCGGCACCCGCGTGAGCGA
GTGTTACGCCGGCAGCAGCCTCGACCGGCTGATCGCGGCGAATTCCACCAATCTGCACGACCTGATGGAGATCTGCGGCC
ATCTGGACTCCTGGGCCCTGGTGCGGGCCATGCGGCACGGCGCCAGCGAACCGAGGGACCGGCTGGTGGCATTGCTGACG
CAGCCGGTGTCGTCCGCGCACTTCGCCGAGCGCGAGGCGGACGTGCGCTTCGCGCTGGCGGAGGCGACCCAGAGCGAGGT
CTTCCTGTGGCTCATGCGCCACCTGTCCCGCGGCCTCGAACGCGCCCAGGCGAGCCCGGCCAGCGAGACCGAGCGGGCGC
TCCAGGTCGCCTCCCACCGGCTGGCGCGAGCGTTGCGCCATGACGACCTGCCGGCGGCGAGCGTGGCGCTGGCGGAGCGC
TCCGCCGCCCTGCTCCAGTGCAACTTCCATGGCGGTTCGACGCCCCGGCGCGGCGTGGGCGACCTTCTGGAAGGCGACGC
CCTGCTCGCGGCCCTCACCATCACCCAGCCCGACCAGTTGCGCGCGCGCCTCGTCGCGGAAATCGGCGTGCTGATGTCGG
AAGCCAAGCTCTCCGACGGCGCCAAGCTGCCGAGCGAGCGCCAGCTCGCCGACCTGTTCGGCGTCAGCCGCATGTCGGTG
CGCGAGGCCCTCGGCGCGCTCAAGGAGCAGGGGCTGGTGCGGGCCAGCGCGCGCACCGGCACCCATGTGTGGCAGGCGCC
CCTCGGCGAGAGCGGGCAGGAGCTGCGCTGCATCGTCCAGCGCAGCGAGGCCAACCTCATGGATGTCTGCGCCCTGCGGC
ATTATCTGGAGGCGTGGTCGTCCCGGCGCGCCGCCGCGTGCGCCAGCGTGGACGATCTTTCCGACATGCGGCGCATCATC
GGCGAGATGCGCCGGCCGATCCCCGCGCTACGGCGCAAGATCGACCTCGACTTCCGCCTGCACCTCACCATCACCCGGGC
GACGGGGAGCGCGGTGGCGCTCTACATCACCGAAGTGCTGCGCGACGTCTACTCGGTTTATTTCGACTATACGCTCACAG
AGCTGTTTTCACCGCAACGCGACAGCCTTTTGCTGGAGCAGCATGTGGAGATCGTCGACGCCATCATGGCCCGCGATCCC
GATCGTGCCGGGCGGGCCATGGAGGCGCACTGCCACATCTTCCGCAATCTCTATGGCCTGCTGCACGACACCGAGCCGCC
CACCGCGCACGCGCTGCATTGA

Upstream 100 bases:

>100_bases
CTGCACAAAATGTGGCAACAAGACCTGCCTTGCCCCGATGATCATCCATCCCTAGTCTTTCCGCCAGCGGGCCGATACGA
GCCCGGCGGGAGGAAAAGGG

Downstream 100 bases:

>100_bases
TTGGGGGCGTTGTCGCCCCCAATTCCTCAGCGGCCGGAGAAGCCGGGCTTGCGTTTGTCGCGGAAGGCGTTCACCGCCTC
CTGGTGGTCGGCGGTGATGT

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSDAALDLKLCLLRGETPSPLDLNSFAGADRIRLRTQTKSAVSDRLAVRLLTLMASGRLPPGARLPPERQIAETVSVSRV
CVRTALERLKSAGYLRSIQGSGTRVSECYAGSSLDRLIAANSTNLHDLMEICGHLDSWALVRAMRHGASEPRDRLVALLT
QPVSSAHFAEREADVRFALAEATQSEVFLWLMRHLSRGLERAQASPASETERALQVASHRLARALRHDDLPAASVALAER
SAALLQCNFHGGSTPRRGVGDLLEGDALLAALTITQPDQLRARLVAEIGVLMSEAKLSDGAKLPSERQLADLFGVSRMSV
REALGALKEQGLVRASARTGTHVWQAPLGESGQELRCIVQRSEANLMDVCALRHYLEAWSSRRAAACASVDDLSDMRRII
GEMRRPIPALRRKIDLDFRLHLTITRATGSAVALYITEVLRDVYSVYFDYTLTELFSPQRDSLLLEQHVEIVDAIMARDP
DRAGRAMEAHCHIFRNLYGLLHDTEPPTAHALH

Sequences:

>Translated_513_residues
MSDAALDLKLCLLRGETPSPLDLNSFAGADRIRLRTQTKSAVSDRLAVRLLTLMASGRLPPGARLPPERQIAETVSVSRV
CVRTALERLKSAGYLRSIQGSGTRVSECYAGSSLDRLIAANSTNLHDLMEICGHLDSWALVRAMRHGASEPRDRLVALLT
QPVSSAHFAEREADVRFALAEATQSEVFLWLMRHLSRGLERAQASPASETERALQVASHRLARALRHDDLPAASVALAER
SAALLQCNFHGGSTPRRGVGDLLEGDALLAALTITQPDQLRARLVAEIGVLMSEAKLSDGAKLPSERQLADLFGVSRMSV
REALGALKEQGLVRASARTGTHVWQAPLGESGQELRCIVQRSEANLMDVCALRHYLEAWSSRRAAACASVDDLSDMRRII
GEMRRPIPALRRKIDLDFRLHLTITRATGSAVALYITEVLRDVYSVYFDYTLTELFSPQRDSLLLEQHVEIVDAIMARDP
DRAGRAMEAHCHIFRNLYGLLHDTEPPTAHALH
>Mature_512_residues
SDAALDLKLCLLRGETPSPLDLNSFAGADRIRLRTQTKSAVSDRLAVRLLTLMASGRLPPGARLPPERQIAETVSVSRVC
VRTALERLKSAGYLRSIQGSGTRVSECYAGSSLDRLIAANSTNLHDLMEICGHLDSWALVRAMRHGASEPRDRLVALLTQ
PVSSAHFAEREADVRFALAEATQSEVFLWLMRHLSRGLERAQASPASETERALQVASHRLARALRHDDLPAASVALAERS
AALLQCNFHGGSTPRRGVGDLLEGDALLAALTITQPDQLRARLVAEIGVLMSEAKLSDGAKLPSERQLADLFGVSRMSVR
EALGALKEQGLVRASARTGTHVWQAPLGESGQELRCIVQRSEANLMDVCALRHYLEAWSSRRAAACASVDDLSDMRRIIG
EMRRPIPALRRKIDLDFRLHLTITRATGSAVALYITEVLRDVYSVYFDYTLTELFSPQRDSLLLEQHVEIVDAIMARDPD
RAGRAMEAHCHIFRNLYGLLHDTEPPTAHALH

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=222, Percent_Identity=30.1801801801802, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789621, Length=213, Percent_Identity=29.5774647887324, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789353, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56437; Mature: 56306

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAALDLKLCLLRGETPSPLDLNSFAGADRIRLRTQTKSAVSDRLAVRLLTLMASGRLP
CCCCHHHHHHHEEECCCCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
PGARLPPERQIAETVSVSRVCVRTALERLKSAGYLRSIQGSGTRVSECYAGSSLDRLIAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHCCCCHHHHHHC
NSTNLHDLMEICGHLDSWALVRAMRHGASEPRDRLVALLTQPVSSAHFAEREADVRFALA
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
EATQSEVFLWLMRHLSRGLERAQASPASETERALQVASHRLARALRHDDLPAASVALAER
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
SAALLQCNFHGGSTPRRGVGDLLEGDALLAALTITQPDQLRARLVAEIGVLMSEAKLSDG
CCEEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
AKLPSERQLADLFGVSRMSVREALGALKEQGLVRASARTGTHVWQAPLGESGQELRCIVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCCCHHHHHHHH
RSEANLMDVCALRHYLEAWSSRRAAACASVDDLSDMRRIIGEMRRPIPALRRKIDLDFRL
HCCCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
HLTITRATGSAVALYITEVLRDVYSVYFDYTLTELFSPQRDSLLLEQHVEIVDAIMARDP
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
DRAGRAMEAHCHIFRNLYGLLHDTEPPTAHALH
CHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDAALDLKLCLLRGETPSPLDLNSFAGADRIRLRTQTKSAVSDRLAVRLLTLMASGRLP
CCCHHHHHHHEEECCCCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
PGARLPPERQIAETVSVSRVCVRTALERLKSAGYLRSIQGSGTRVSECYAGSSLDRLIAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHCCCCHHHHHHC
NSTNLHDLMEICGHLDSWALVRAMRHGASEPRDRLVALLTQPVSSAHFAEREADVRFALA
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
EATQSEVFLWLMRHLSRGLERAQASPASETERALQVASHRLARALRHDDLPAASVALAER
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
SAALLQCNFHGGSTPRRGVGDLLEGDALLAALTITQPDQLRARLVAEIGVLMSEAKLSDG
CCEEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
AKLPSERQLADLFGVSRMSVREALGALKEQGLVRASARTGTHVWQAPLGESGQELRCIVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCCCHHHHHHHH
RSEANLMDVCALRHYLEAWSSRRAAACASVDDLSDMRRIIGEMRRPIPALRRKIDLDFRL
HCCCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEE
HLTITRATGSAVALYITEVLRDVYSVYFDYTLTELFSPQRDSLLLEQHVEIVDAIMARDP
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
DRAGRAMEAHCHIFRNLYGLLHDTEPPTAHALH
CHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]