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The map label for this gene is degP [H]

Identifier: 154245605

GI number: 154245605

Start: 1880330

End: 1881826

Strand: Reverse

Name: degP [H]

Synonym: Xaut_1661

Alternate gene names: 154245605

Gene position: 1881826-1880330 (Counterclockwise)

Preceding gene: 154245606

Following gene: 154245603

Centisome position: 35.45

GC content: 67.87

Gene sequence:

>1497_bases
ATGCCCCACCCGCTTCGTTCCTCAGCTCCTGCCGCCCGCCTGCCCGCCTTCGTCCTGGCAGCCGCCCTCGCACTCCTCAC
CGCGACCTTTTCCACCCTCGCCCCGGCTCCGCTGCTGGCGGCGCCCGGCAAGGGGCCGGACACGGTGGCGGACGTGGCCG
AGCGGGTCATGGACGCGGTGGTGAACATCTCCACCTCGCAGAACGTGGCTGCCTCGCGCTCGGTGCCCCAGCCGCAGCTG
CCGCCGGGCTCGCCGTTCGAGGACTTCTTTGATGAATTCTTCAAGAAGAGGCAGGATGACGGCGGCGAGCAGCGCTCGCG
CCGCGTGTCCTCCCTCGGCTCGGGCTTCGTCATCGACCCGTCCGGCCTCATCGTGACCAACAATCACGTGATCGCCGACG
CCGACGAGATCTTCGCCAATTTCAACGACGGCTCGAAGCTGAAGGCCGAGCTGATCGGCCGCGACACCAAGACCGACCTC
GCCCTGCTGCGTGTGAAGCCCGACAAGCCGCTGGTGGCGGTGAAGTTCGGCGACAGCGAGAAGCTGCGGGTGGGCGACTG
GGTGATGGCCATCGGCAACCCGTTCGGCCTCGGCGGCACGCTGACGGTTGGCGTGGTCTCCGCCCGCAACCGCGACATCA
ATTCCGGCCCCTACGACAATTTCATCCAGACCGACGCCGCCATCAATCGCGGCAATTCCGGCGGCCCGCTGTTCAACATG
GACGGCGAGGTGATCGGCATCAACACCGCCATCATCTCGCCCTCGGGCGGCTCCATCGGCATCGGCTTCGCGGTGCCGTC
CGCCACCGCCAAGCCGGTGATCGCCCAGCTCGGCGAGTTCAAGGAAGTGCGGCGCGGCTGGATCGGGGTGCGCATCCAGC
CGGTCACCGACGACATCGCCGAGAGCCTCGGCCTCGGCAAGCCGCGCGGCGCGCTCATCGGCGTGGTCTCGGAGAACAGC
CCGGCGGCGCGGGGCGGCATCAAGGCCGGCGACGTGATCGTGAAGTTCAATGGCCGCGACATCAAGGAGGTGCGCGACCT
CACCCGCACCGTGGCCGACGCCATGGCGGACACCGAGGTGGAGGTGGTGGTGGTCCGCAAGGGCAAGGAAGAGACCCTGC
ACCTCAAGGTCGCCCGCATGCCCGAGGACGATAAGCCGGAGACCCCCAAGCCCGCCGCCGAGTCGCAGAAAGTAGCGCCC
AAAAAAGCCCTCGGCATCGAGCTCTCCGCCATGAGCGACGAGCTGCGCAAGCGCTATTCCATCAAGAGCGAGATCAACGG
CGTGGTCATCACCGGCGTCGATGCCTCCACCCCTGCCTCGGACAAGGGGCTGAAGGCCGGGCAGGTCATCGTCCAGGTGG
GGCAGGAAGCGGTGGCGAGCCCCTCCGACGTGGAGAAGCAGGTGGATGCCCTGCGCAAGCAGGGCAAGCGCTCCGCCCTG
CTCCTCGTCTCCGATGGCGAGGGCAAGCAGGAGTTCGTGACGATCCCGCTGAACTGA

Upstream 100 bases:

>100_bases
GCCTCCGGTGTAGCCGACGCCGGATCGTGACCGTCCGGGGCTTGCGCCCACGCGGCGGCCGGTTCAGCCTCAAGGAACGA
CCGCCGCGTCGAGGAGAGAC

Downstream 100 bases:

>100_bases
GCTGACGCGCCGCCGTCATCCCCGGCTGGTCCGGGGCATGACGGCGGCGTAAGGGTACAGGGAGAGCTTATCCCGCCTCA
GGCGGTGTGGAACTCGCTCA

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MPHPLRSSAPAARLPAFVLAAALALLTATFSTLAPAPLLAAPGKGPDTVADVAERVMDAVVNISTSQNVAASRSVPQPQL
PPGSPFEDFFDEFFKKRQDDGGEQRSRRVSSLGSGFVIDPSGLIVTNNHVIADADEIFANFNDGSKLKAELIGRDTKTDL
ALLRVKPDKPLVAVKFGDSEKLRVGDWVMAIGNPFGLGGTLTVGVVSARNRDINSGPYDNFIQTDAAINRGNSGGPLFNM
DGEVIGINTAIISPSGGSIGIGFAVPSATAKPVIAQLGEFKEVRRGWIGVRIQPVTDDIAESLGLGKPRGALIGVVSENS
PAARGGIKAGDVIVKFNGRDIKEVRDLTRTVADAMADTEVEVVVVRKGKEETLHLKVARMPEDDKPETPKPAAESQKVAP
KKALGIELSAMSDELRKRYSIKSEINGVVITGVDASTPASDKGLKAGQVIVQVGQEAVASPSDVEKQVDALRKQGKRSAL
LLVSDGEGKQEFVTIPLN

Sequences:

>Translated_498_residues
MPHPLRSSAPAARLPAFVLAAALALLTATFSTLAPAPLLAAPGKGPDTVADVAERVMDAVVNISTSQNVAASRSVPQPQL
PPGSPFEDFFDEFFKKRQDDGGEQRSRRVSSLGSGFVIDPSGLIVTNNHVIADADEIFANFNDGSKLKAELIGRDTKTDL
ALLRVKPDKPLVAVKFGDSEKLRVGDWVMAIGNPFGLGGTLTVGVVSARNRDINSGPYDNFIQTDAAINRGNSGGPLFNM
DGEVIGINTAIISPSGGSIGIGFAVPSATAKPVIAQLGEFKEVRRGWIGVRIQPVTDDIAESLGLGKPRGALIGVVSENS
PAARGGIKAGDVIVKFNGRDIKEVRDLTRTVADAMADTEVEVVVVRKGKEETLHLKVARMPEDDKPETPKPAAESQKVAP
KKALGIELSAMSDELRKRYSIKSEINGVVITGVDASTPASDKGLKAGQVIVQVGQEAVASPSDVEKQVDALRKQGKRSAL
LLVSDGEGKQEFVTIPLN
>Mature_497_residues
PHPLRSSAPAARLPAFVLAAALALLTATFSTLAPAPLLAAPGKGPDTVADVAERVMDAVVNISTSQNVAASRSVPQPQLP
PGSPFEDFFDEFFKKRQDDGGEQRSRRVSSLGSGFVIDPSGLIVTNNHVIADADEIFANFNDGSKLKAELIGRDTKTDLA
LLRVKPDKPLVAVKFGDSEKLRVGDWVMAIGNPFGLGGTLTVGVVSARNRDINSGPYDNFIQTDAAINRGNSGGPLFNMD
GEVIGINTAIISPSGGSIGIGFAVPSATAKPVIAQLGEFKEVRRGWIGVRIQPVTDDIAESLGLGKPRGALIGVVSENSP
AARGGIKAGDVIVKFNGRDIKEVRDLTRTVADAMADTEVEVVVVRKGKEETLHLKVARMPEDDKPETPKPAAESQKVAPK
KALGIELSAMSDELRKRYSIKSEINGVVITGVDASTPASDKGLKAGQVIVQVGQEAVASPSDVEKQVDALRKQGKRSALL
LVSDGEGKQEFVTIPLN

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=354, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4506141, Length=298, Percent_Identity=34.8993288590604, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=276, Percent_Identity=31.8840579710145, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI7019477, Length=285, Percent_Identity=37.8947368421053, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1786356, Length=440, Percent_Identity=38.4090909090909, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1789629, Length=460, Percent_Identity=36.0869565217391, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1789630, Length=277, Percent_Identity=36.8231046931408, Blast_Score=168, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24646839, Length=305, Percent_Identity=34.0983606557377, Blast_Score=152, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52453; Mature: 52322

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPLRSSAPAARLPAFVLAAALALLTATFSTLAPAPLLAAPGKGPDTVADVAERVMDAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHH
VNISTSQNVAASRSVPQPQLPPGSPFEDFFDEFFKKRQDDGGEQRSRRVSSLGSGFVIDP
HCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
SGLIVTNNHVIADADEIFANFNDGSKLKAELIGRDTKTDLALLRVKPDKPLVAVKFGDSE
CCEEEECCEEEECHHHHHEECCCCCEEEHHHHCCCCCCCEEEEEECCCCCEEEEEECCCC
KLRVGDWVMAIGNPFGLGGTLTVGVVSARNRDINSGPYDNFIQTDAAINRGNSGGPLFNM
CEEECCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCEEEC
DGEVIGINTAIISPSGGSIGIGFAVPSATAKPVIAQLGEFKEVRRGWIGVRIQPVTDDIA
CCCEEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCHHHH
ESLGLGKPRGALIGVVSENSPAARGGIKAGDVIVKFNGRDIKEVRDLTRTVADAMADTEV
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCE
EVVVVRKGKEETLHLKVARMPEDDKPETPKPAAESQKVAPKKALGIELSAMSDELRKRYS
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCEEHHHHHHHHHHHHH
IKSEINGVVITGVDASTPASDKGLKAGQVIVQVGQEAVASPSDVEKQVDALRKQGKRSAL
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEE
LLVSDGEGKQEFVTIPLN
EEEECCCCCCEEEEEECC
>Mature Secondary Structure 
PHPLRSSAPAARLPAFVLAAALALLTATFSTLAPAPLLAAPGKGPDTVADVAERVMDAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHH
VNISTSQNVAASRSVPQPQLPPGSPFEDFFDEFFKKRQDDGGEQRSRRVSSLGSGFVIDP
HCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
SGLIVTNNHVIADADEIFANFNDGSKLKAELIGRDTKTDLALLRVKPDKPLVAVKFGDSE
CCEEEECCEEEECHHHHHEECCCCCEEEHHHHCCCCCCCEEEEEECCCCCEEEEEECCCC
KLRVGDWVMAIGNPFGLGGTLTVGVVSARNRDINSGPYDNFIQTDAAINRGNSGGPLFNM
CEEECCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHCCHHHCCCCCCCCEEEC
DGEVIGINTAIISPSGGSIGIGFAVPSATAKPVIAQLGEFKEVRRGWIGVRIQPVTDDIA
CCCEEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCHHHH
ESLGLGKPRGALIGVVSENSPAARGGIKAGDVIVKFNGRDIKEVRDLTRTVADAMADTEV
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCE
EVVVVRKGKEETLHLKVARMPEDDKPETPKPAAESQKVAPKKALGIELSAMSDELRKRYS
EEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCEEHHHHHHHHHHHHH
IKSEINGVVITGVDASTPASDKGLKAGQVIVQVGQEAVASPSDVEKQVDALRKQGKRSAL
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEE
LLVSDGEGKQEFVTIPLN
EEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]