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The map label for this gene is pleC [H]

Identifier: 154245571

GI number: 154245571

Start: 1842314

End: 1844626

Strand: Reverse

Name: pleC [H]

Synonym: Xaut_1626

Alternate gene names: 154245571

Gene position: 1844626-1842314 (Counterclockwise)

Preceding gene: 154245573

Following gene: 154245570

Centisome position: 34.75

GC content: 68.83

Gene sequence:

>2313_bases
ATGGCACGCGCCAACGCTGCGAGCGTCGGCGCGCGCGACCAAGCCATTCGAGGTCTGGCACGGTCGATCGCGCGCCCTGC
CTACCAGCGACTGCTCGATGCGGAGCCGGTCCTGCGCAGGATCGTCCCGGCGCTCATCGTCACCTTCCTGGTGGTGATCG
GGGTCGGCGCGGTGGTGCAGATCCACGCCCACCGGGTGGCCGAGCTCAACAACGCCAAGGACGACCTCTCCCTCCTCGCC
CTCGCCACCGCCGAGGGCCTGACCCTGCGCGCCGGCAATTCCCTCGCCCGCGTGCCCTCCGCCCTGGAGGAGAGCCTGCC
GCCCCGCGCCACCGAGAGCGGGCGGCGCGCCTATGTCACCGACGCCCAGGGCCGCATCATCGCCTCCGCGCCCCGCAGCG
AGGCGCCGGCCAACCTTGCCGACCTGATCGACCCGGCCCAGCCCCTCGTCATCTTCGCCGAGCGCGCCGGCGTGCTGGAA
GTGCCGTTCGGCACCGGCACCGCGCTCGCCACGGTACGCAACCTGTCGGCGCCGCTGGGGCAGATCGTGTTCCTCCAGCC
CACCGAGCGGGCGCTCGCATCCTGGTCGGATTCCACCACGCTGACGGTGACGCTGTTCACCACCACCGGCACGGTGCTGC
TCATTCTCGGCTTCTCGTTCCACTGGCAGGCGAGCCGGGCGCGCGAAGCGGACGCCATCTACGACACCGTGCGCCGGCGC
ATCGACACCGCGCTCAACCGCGGCCGTTGCGGCATGTGGGACTGGGACATGGCCCGCGGCCGCATGTACTGGTCCGACAC
CATGTTCGAGATCCTCGGGCTGGAGCGCAAGGACGAGCTGGTGTCCTTCGGCGAGATCGCCAAGCTCGTGCATCCCGACG
ACGGCGACCTCTACGAGCTGGCGCAGGAGCTGGCCGAGCGGCCGGGCACGCCGGTGGACCGGGTGTTCCGCATGCGCACC
GCCAAGGGCGACTTCGTATGGCTGCGCATGCGCGCCGAAGTGGTCCAGCAGCAGGGCGAGGACGGCCCCCACCTCATCGG
CATCGCCATGGATGTCACCGAGGCCCAGCGCATGGCCGAGCGCACGGTGACCGCCGACATGCGCCTGCGCGACGCCATCG
AGAGCATCTCGGAAGCCTTCGTGCTGTGGGACAGCCAGAACCGGCTGGTGCTGTGCAATTCCAAGTTCCAGTCCCTGCAC
GAGCTGCCCGACGAGGCCATCCACGCCGGCACCCCGTTCGACGTGATCGCCTCCGTCGGCCGCCACCCCATCACCCGCAC
CCCGCTGAAGCCCGAGGACAAGCCCGAGGAAGGCTCGCGCGCCTTCGAGGCCCAGCTCTCCAACGGCCGCTGGCTGAAGA
TCGCCGAGCGCCGCACCAAGGACAACGGCTACGTCTCGGTCGGCACCGACATCACCACCATGAAGCGCCACGAGGAGCGC
CTCATGGACAATGAGAAGCGCCTGATGGCGCTGGTGGCGGACCTGCGCAAGTCCCAGCAGACCCTGGAGCACCAGGCCCA
GCAGCTGGCGGAACTGGCGGAGAAATATTCGGAAGAACGCAACAAGGCCGAGGACGCCAACCGCGCCAAGAGCGAGTTCC
TCGCCAACATGTCCCACGAGCTGCGCACGCCGCTCAACGCCATCATCGGCTTCTCGGAGATCATGGAGAGCGGCATGTTC
GGCCCGCTCGGCTCGGAGAAATACGCCGAATACTGCACCGACATCAAAGGCTCCGGCACCTACCTGCTCGACGTCATCAA
CGACATCCTCGACATGTCGAAGATCGAGGCCGGCCGCATGCAGCTGGAGGTGGAGGACCTGGCGCTCGACGACATCATCG
CCGACGCCCTGCGCGTCACGGCGGTGAACGGCGACGAGAAGAACATCGCCATGACCATGGCGGCGGCCCCCAACCTCGCC
ATCAAGGGCGACCGCCGGGCGCTGAAGCAGATCCTGCTGAACCTGCTCTCCAACGCGGTGAAATTCACCCCCGAGGGCGG
CAACATCGCGGTGAAGGCGCGCATCAACGGCGCGGCGGCGGTGATCGCCATCGAGGACACCGGCATCGGCATCGCCAAGG
ACGCGCTGGCGCGGATCGGGCGGCCGTTCGAGCAGGTGGAGAGCCAGTTCACCAAGACCCACAAGGGCTCGGGCCTCGGC
CTTGCCATCGCCAAGTCGCTGGTGGAGTTGCACGGCGGCGCCATGCGCATCCGCTCCGTCGAGGGCCGCGGCACCACCGT
AATCGTCCGCCTGCCGGTGAACGGCCGCGCCGCCAATTCCAACGAGACGCCAAGGCTGGCCGCGGTGATGTGA

Upstream 100 bases:

>100_bases
CGATTCGGAGAGATGCGGCACGTCCCTCCAGATCTAGGACGTGGGGGCTCAAGAGCAGTAGGCCGCTCAACGGCCCCCGG
ACACCCGGAGGAGACCGGCG

Downstream 100 bases:

>100_bases
GGGCGGCGGCCCGGCCTGAACACCTCAGCCGTTGCCGCCGTTGTCGTTGCCCTGTCCCCGCCCGATCCCGTCCGCCAGAG
GCCGCAGCAGGAAGCCAAGG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MARANAASVGARDQAIRGLARSIARPAYQRLLDAEPVLRRIVPALIVTFLVVIGVGAVVQIHAHRVAELNNAKDDLSLLA
LATAEGLTLRAGNSLARVPSALEESLPPRATESGRRAYVTDAQGRIIASAPRSEAPANLADLIDPAQPLVIFAERAGVLE
VPFGTGTALATVRNLSAPLGQIVFLQPTERALASWSDSTTLTVTLFTTTGTVLLILGFSFHWQASRAREADAIYDTVRRR
IDTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERKDELVSFGEIAKLVHPDDGDLYELAQELAERPGTPVDRVFRMRT
AKGDFVWLRMRAEVVQQQGEDGPHLIGIAMDVTEAQRMAERTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQSLH
ELPDEAIHAGTPFDVIASVGRHPITRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDNGYVSVGTDITTMKRHEER
LMDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEERNKAEDANRAKSEFLANMSHELRTPLNAIIGFSEIMESGMF
GPLGSEKYAEYCTDIKGSGTYLLDVINDILDMSKIEAGRMQLEVEDLALDDIIADALRVTAVNGDEKNIAMTMAAAPNLA
IKGDRRALKQILLNLLSNAVKFTPEGGNIAVKARINGAAAVIAIEDTGIGIAKDALARIGRPFEQVESQFTKTHKGSGLG
LAIAKSLVELHGGAMRIRSVEGRGTTVIVRLPVNGRAANSNETPRLAAVM

Sequences:

>Translated_770_residues
MARANAASVGARDQAIRGLARSIARPAYQRLLDAEPVLRRIVPALIVTFLVVIGVGAVVQIHAHRVAELNNAKDDLSLLA
LATAEGLTLRAGNSLARVPSALEESLPPRATESGRRAYVTDAQGRIIASAPRSEAPANLADLIDPAQPLVIFAERAGVLE
VPFGTGTALATVRNLSAPLGQIVFLQPTERALASWSDSTTLTVTLFTTTGTVLLILGFSFHWQASRAREADAIYDTVRRR
IDTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERKDELVSFGEIAKLVHPDDGDLYELAQELAERPGTPVDRVFRMRT
AKGDFVWLRMRAEVVQQQGEDGPHLIGIAMDVTEAQRMAERTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQSLH
ELPDEAIHAGTPFDVIASVGRHPITRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDNGYVSVGTDITTMKRHEER
LMDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEERNKAEDANRAKSEFLANMSHELRTPLNAIIGFSEIMESGMF
GPLGSEKYAEYCTDIKGSGTYLLDVINDILDMSKIEAGRMQLEVEDLALDDIIADALRVTAVNGDEKNIAMTMAAAPNLA
IKGDRRALKQILLNLLSNAVKFTPEGGNIAVKARINGAAAVIAIEDTGIGIAKDALARIGRPFEQVESQFTKTHKGSGLG
LAIAKSLVELHGGAMRIRSVEGRGTTVIVRLPVNGRAANSNETPRLAAVM
>Mature_769_residues
ARANAASVGARDQAIRGLARSIARPAYQRLLDAEPVLRRIVPALIVTFLVVIGVGAVVQIHAHRVAELNNAKDDLSLLAL
ATAEGLTLRAGNSLARVPSALEESLPPRATESGRRAYVTDAQGRIIASAPRSEAPANLADLIDPAQPLVIFAERAGVLEV
PFGTGTALATVRNLSAPLGQIVFLQPTERALASWSDSTTLTVTLFTTTGTVLLILGFSFHWQASRAREADAIYDTVRRRI
DTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERKDELVSFGEIAKLVHPDDGDLYELAQELAERPGTPVDRVFRMRTA
KGDFVWLRMRAEVVQQQGEDGPHLIGIAMDVTEAQRMAERTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQSLHE
LPDEAIHAGTPFDVIASVGRHPITRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDNGYVSVGTDITTMKRHEERL
MDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEERNKAEDANRAKSEFLANMSHELRTPLNAIIGFSEIMESGMFG
PLGSEKYAEYCTDIKGSGTYLLDVINDILDMSKIEAGRMQLEVEDLALDDIIADALRVTAVNGDEKNIAMTMAAAPNLAI
KGDRRALKQILLNLLSNAVKFTPEGGNIAVKARINGAAAVIAIEDTGIGIAKDALARIGRPFEQVESQFTKTHKGSGLGL
AIAKSLVELHGGAMRIRSVEGRGTTVIVRLPVNGRAANSNETPRLAAVM

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=36.7816091954023, Blast_Score=149, Evalue=8e-37,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=33.0935251798561, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=36, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=36.734693877551, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI48994928, Length=370, Percent_Identity=30, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=29.9595141700405, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=31.3304721030043, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=29.3333333333333, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786783, Length=263, Percent_Identity=27.7566539923954, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=25.0996015936255, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=29.1304347826087, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=27.9352226720648, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=233, Percent_Identity=25.3218884120172, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=24.6753246753247, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=264, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=222, Percent_Identity=32.4324324324324, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84280; Mature: 84149

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARANAASVGARDQAIRGLARSIARPAYQRLLDAEPVLRRIVPALIVTFLVVIGVGAVVQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHEE
IHAHRVAELNNAKDDLSLLALATAEGLTLRAGNSLARVPSALEESLPPRATESGRRAYVT
HHHHHHHHHCCCHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
DAQGRIIASAPRSEAPANLADLIDPAQPLVIFAERAGVLEVPFGTGTALATVRNLSAPLG
CCCCCEEECCCCCCCCCCHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHCCCCCC
QIVFLQPTERALASWSDSTTLTVTLFTTTGTVLLILGFSFHWQASRAREADAIYDTVRRR
CEEEECCHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCEECCHHHHHHHHHHHHHHHH
IDTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERKDELVSFGEIAKLVHPDDGDLYEL
HHHHHCCCCCCCCCHHHHCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
AQELAERPGTPVDRVFRMRTAKGDFVWLRMRAEVVQQQGEDGPHLIGIAMDVTEAQRMAE
HHHHHHCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
RTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQSLHELPDEAIHAGTPFDVIASVG
HHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECHHHHHHHHCCHHHHCCCCCHHHHHHCC
RHPITRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDNGYVSVGTDITTMKRHEER
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHCCCCCCEEEECCCHHHHHHHHHH
LMDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEERNKAEDANRAKSEFLANMSHE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPLNAIIGFSEIMESGMFGPLGSEKYAEYCTDIKGSGTYLLDVINDILDMSKIEAGRM
HHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCE
QLEVEDLALDDIIADALRVTAVNGDEKNIAMTMAAAPNLAIKGDRRALKQILLNLLSNAV
EEEHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHE
KFTPEGGNIAVKARINGAAAVIAIEDTGIGIAKDALARIGRPFEQVESQFTKTHKGSGLG
EECCCCCCEEEEEEECCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCH
LAIAKSLVELHGGAMRIRSVEGRGTTVIVRLPVNGRAANSNETPRLAAVM
HHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
ARANAASVGARDQAIRGLARSIARPAYQRLLDAEPVLRRIVPALIVTFLVVIGVGAVVQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHEE
IHAHRVAELNNAKDDLSLLALATAEGLTLRAGNSLARVPSALEESLPPRATESGRRAYVT
HHHHHHHHHCCCHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
DAQGRIIASAPRSEAPANLADLIDPAQPLVIFAERAGVLEVPFGTGTALATVRNLSAPLG
CCCCCEEECCCCCCCCCCHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHCCCCCC
QIVFLQPTERALASWSDSTTLTVTLFTTTGTVLLILGFSFHWQASRAREADAIYDTVRRR
CEEEECCHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCEECCHHHHHHHHHHHHHHHH
IDTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERKDELVSFGEIAKLVHPDDGDLYEL
HHHHHCCCCCCCCCHHHHCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
AQELAERPGTPVDRVFRMRTAKGDFVWLRMRAEVVQQQGEDGPHLIGIAMDVTEAQRMAE
HHHHHHCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
RTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQSLHELPDEAIHAGTPFDVIASVG
HHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECHHHHHHHHCCHHHHCCCCCHHHHHHCC
RHPITRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDNGYVSVGTDITTMKRHEER
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHCCCCCCEEEECCCHHHHHHHHHH
LMDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEERNKAEDANRAKSEFLANMSHE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPLNAIIGFSEIMESGMFGPLGSEKYAEYCTDIKGSGTYLLDVINDILDMSKIEAGRM
HHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCE
QLEVEDLALDDIIADALRVTAVNGDEKNIAMTMAAAPNLAIKGDRRALKQILLNLLSNAV
EEEHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHE
KFTPEGGNIAVKARINGAAAVIAIEDTGIGIAKDALARIGRPFEQVESQFTKTHKGSGLG
EECCCCCCEEEEEEECCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCH
LAIAKSLVELHGGAMRIRSVEGRGTTVIVRLPVNGRAANSNETPRLAAVM
HHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]