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The map label for this gene is ampH [H]

Identifier: 154245570

GI number: 154245570

Start: 1839591

End: 1841192

Strand: Reverse

Name: ampH [H]

Synonym: Xaut_1625

Alternate gene names: 154245570

Gene position: 1841192-1839591 (Counterclockwise)

Preceding gene: 154245571

Following gene: 154245565

Centisome position: 34.68

GC content: 68.79

Gene sequence:

>1602_bases
ATGGCCCACAGGCGTTTTCCCCGAACAGGCCGGCACGCCGGCCTGTCCTGTACCGCCCTCGCCCTCCTCCTCCTCGCCTC
CCCCGCCCTCGCCCAGACCCAGATCGACGCCTCCCGGCCGCCGCCGCAGACATCCGGCGTGCCCATCCCCAAAGGGCAGA
TCGAGACCGCGGTGGGCAAGGTCGACGCCCTCGCGCGGGACCTCATGACGCGCTCCGGCATTCCCGGCCTCGCGGTGGCC
GTGGTGCACGAGGGCAAGACCGTGTTCCTCAAGGGCTATGGCGTGCGCAAGGTCGGCGAGAGCGCGGCCATCGACGCGGA
CACCGTGTTCCAGCTTGCCTCCCTGTCGAAGTCGGTGGGCTCAAGCGTGGTAGCCCACGAGGTGGGCAAGGGCACGGTGA
AGTGGGACACCCCGGTGGAGGACCTTTTGCCCTGGTTCGCCCTGAACGACGACTGGGTGTCCGAGCACGTCACCATCGCC
GATCTCTACAGCCATCGCTCGGGCCTGCCGGACCATGCCGGCGACGAACTGGAAGACCTCGGCTACGACCGCCGGCAGGT
GCTTGAGCGGCTGAAGAAGCTGCCCCTCGCCCCGTTCCGCGTCTCCTATGCCTATACCAATTTCGGCGTCACCGCCGCCG
CCGAGGCGGTGGCCACCGCTTCGGGCAAGGACTGGGAGACCCTCTCGGAGGAAGTGCTCTACAAGCCGCTCGGCATGGCC
TCCACCTCCTCGCGCTTTTCCGACTACATGGCCCGCTCCAACCGCGCCGTGCCCCATGTGCGGGTGGGCAAGATCGGCGA
GAGCAAGACCTTCGCCGCCAAGTTCCAGCGCGATCCGCAGGCCCAGTCCCCGGCGGGCGGGGTGAGTTCGTCGGTGCGGG
ACATGGCCCGCTGGCTCGGCTTCGTGCTGGGCGGCGGCACCTATGAGGGCCGGCAGATCGTGCCCGAGAAGGCGCTGCTG
CCCGCCATGCGGCCGGAGATGATCTCCTCGCCCGCCTATGCCGCCGATGCCCGCGCCGGCTTCTACGGCTATGGCTTCGC
GGTGAACGTGTCGCCCGCCGGCCGGGTGATGATCGACCATTCCGGCGCCTTCATCCTCGGCGCCGGCACAACCTATGTGC
TCCTGCCGTCCGAGAAGCTGGGCATCGTGGTGCTCACCAATGCCCAGCCAACCGGCGTGCCTGAGGCGTTGGCCGCGAGC
TTCATGGACCTTGCCCAGTTCGGCACGGTGACGCGGGACTGGCTCACGGCCTACGGCCCGCTCATCGATCCGCTCTACAC
GCCGCTCGGCACCCTCGCCGGCAAGAGCGCGCCCGCCAGGCCCACGCCGGCCAAGCCGCTTGCCACCTATGTGGGCACCT
ATGCCAATGCCTATTTCGGCGAGGCGCGGGTGAGCGAGGACAAGGGCCGCCTCATCCTTACCGTGGGGCCGAAGCCGCGC
GTCTTCACCCTCGACCACTGGAGCGGGGACGACTTCATCTTCCGCCCCGAGGGCGAGGAGACGGCGCCTGTGGGATCGGT
GTCGCAGGTGACCTTCTCGGACCGGAGGATGAAGGTGGAATTCTTCAACGACAACGGCCTCGGCACCTTCGAGCGGCGGT
GA

Upstream 100 bases:

>100_bases
CCCGTCCATCCGCCCCCTTGCGGGCCGCCCGCCCCTGCCGCTAAGCCTGGAGCCACAAGCAGCCTGCGCCGGTGAGCGCA
GGCGGATGGAGGCAGCACCC

Downstream 100 bases:

>100_bases
GGGCCGGGGTGGCGCCATAAGGCCATACATAGACCACCGTCGCCGTCCGGCGTGACCGGACGGCCCATGGCCCGGCCGGC
ACAACGCTGCGGGGACAACG

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MAHRRFPRTGRHAGLSCTALALLLLASPALAQTQIDASRPPPQTSGVPIPKGQIETAVGKVDALARDLMTRSGIPGLAVA
VVHEGKTVFLKGYGVRKVGESAAIDADTVFQLASLSKSVGSSVVAHEVGKGTVKWDTPVEDLLPWFALNDDWVSEHVTIA
DLYSHRSGLPDHAGDELEDLGYDRRQVLERLKKLPLAPFRVSYAYTNFGVTAAAEAVATASGKDWETLSEEVLYKPLGMA
STSSRFSDYMARSNRAVPHVRVGKIGESKTFAAKFQRDPQAQSPAGGVSSSVRDMARWLGFVLGGGTYEGRQIVPEKALL
PAMRPEMISSPAYAADARAGFYGYGFAVNVSPAGRVMIDHSGAFILGAGTTYVLLPSEKLGIVVLTNAQPTGVPEALAAS
FMDLAQFGTVTRDWLTAYGPLIDPLYTPLGTLAGKSAPARPTPAKPLATYVGTYANAYFGEARVSEDKGRLILTVGPKPR
VFTLDHWSGDDFIFRPEGEETAPVGSVSQVTFSDRRMKVEFFNDNGLGTFERR

Sequences:

>Translated_533_residues
MAHRRFPRTGRHAGLSCTALALLLLASPALAQTQIDASRPPPQTSGVPIPKGQIETAVGKVDALARDLMTRSGIPGLAVA
VVHEGKTVFLKGYGVRKVGESAAIDADTVFQLASLSKSVGSSVVAHEVGKGTVKWDTPVEDLLPWFALNDDWVSEHVTIA
DLYSHRSGLPDHAGDELEDLGYDRRQVLERLKKLPLAPFRVSYAYTNFGVTAAAEAVATASGKDWETLSEEVLYKPLGMA
STSSRFSDYMARSNRAVPHVRVGKIGESKTFAAKFQRDPQAQSPAGGVSSSVRDMARWLGFVLGGGTYEGRQIVPEKALL
PAMRPEMISSPAYAADARAGFYGYGFAVNVSPAGRVMIDHSGAFILGAGTTYVLLPSEKLGIVVLTNAQPTGVPEALAAS
FMDLAQFGTVTRDWLTAYGPLIDPLYTPLGTLAGKSAPARPTPAKPLATYVGTYANAYFGEARVSEDKGRLILTVGPKPR
VFTLDHWSGDDFIFRPEGEETAPVGSVSQVTFSDRRMKVEFFNDNGLGTFERR
>Mature_532_residues
AHRRFPRTGRHAGLSCTALALLLLASPALAQTQIDASRPPPQTSGVPIPKGQIETAVGKVDALARDLMTRSGIPGLAVAV
VHEGKTVFLKGYGVRKVGESAAIDADTVFQLASLSKSVGSSVVAHEVGKGTVKWDTPVEDLLPWFALNDDWVSEHVTIAD
LYSHRSGLPDHAGDELEDLGYDRRQVLERLKKLPLAPFRVSYAYTNFGVTAAAEAVATASGKDWETLSEEVLYKPLGMAS
TSSRFSDYMARSNRAVPHVRVGKIGESKTFAAKFQRDPQAQSPAGGVSSSVRDMARWLGFVLGGGTYEGRQIVPEKALLP
AMRPEMISSPAYAADARAGFYGYGFAVNVSPAGRVMIDHSGAFILGAGTTYVLLPSEKLGIVVLTNAQPTGVPEALAASF
MDLAQFGTVTRDWLTAYGPLIDPLYTPLGTLAGKSAPARPTPAKPLATYVGTYANAYFGEARVSEDKGRLILTVGPKPRV
FTLDHWSGDDFIFRPEGEETAPVGSVSQVTFSDRRMKVEFFNDNGLGTFERR

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=355, Percent_Identity=26.1971830985915, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=365, Percent_Identity=22.7397260273973, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 57178; Mature: 57047

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHRRFPRTGRHAGLSCTALALLLLASPALAQTQIDASRPPPQTSGVPIPKGQIETAVGK
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
VDALARDLMTRSGIPGLAVAVVHEGKTVFLKGYGVRKVGESAAIDADTVFQLASLSKSVG
HHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHC
SSVVAHEVGKGTVKWDTPVEDLLPWFALNDDWVSEHVTIADLYSHRSGLPDHAGDELEDL
CHHHHHHCCCCEEEECCCHHHHHHHHCCCCCHHHCCEEHHHHHHHCCCCCCCCCCHHHHC
GYDRRQVLERLKKLPLAPFRVSYAYTNFGVTAAAEAVATASGKDWETLSEEVLYKPLGMA
CCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
STSSRFSDYMARSNRAVPHVRVGKIGESKTFAAKFQRDPQAQSPAGGVSSSVRDMARWLG
CHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
FVLGGGTYEGRQIVPEKALLPAMRPEMISSPAYAADARAGFYGYGFAVNVSPAGRVMIDH
HHHCCCCCCCCEECCHHHHCCCCCHHHHCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEC
SGAFILGAGTTYVLLPSEKLGIVVLTNAQPTGVPEALAASFMDLAQFGTVTRDWLTAYGP
CCCEEEECCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCH
LIDPLYTPLGTLAGKSAPARPTPAKPLATYVGTYANAYFGEARVSEDKGRLILTVGPKPR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEEEECCCCC
VFTLDHWSGDDFIFRPEGEETAPVGSVSQVTFSDRRMKVEFFNDNGLGTFERR
EEEEECCCCCCEEECCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AHRRFPRTGRHAGLSCTALALLLLASPALAQTQIDASRPPPQTSGVPIPKGQIETAVGK
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
VDALARDLMTRSGIPGLAVAVVHEGKTVFLKGYGVRKVGESAAIDADTVFQLASLSKSVG
HHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHC
SSVVAHEVGKGTVKWDTPVEDLLPWFALNDDWVSEHVTIADLYSHRSGLPDHAGDELEDL
CHHHHHHCCCCEEEECCCHHHHHHHHCCCCCHHHCCEEHHHHHHHCCCCCCCCCCHHHHC
GYDRRQVLERLKKLPLAPFRVSYAYTNFGVTAAAEAVATASGKDWETLSEEVLYKPLGMA
CCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
STSSRFSDYMARSNRAVPHVRVGKIGESKTFAAKFQRDPQAQSPAGGVSSSVRDMARWLG
CHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
FVLGGGTYEGRQIVPEKALLPAMRPEMISSPAYAADARAGFYGYGFAVNVSPAGRVMIDH
HHHCCCCCCCCEECCHHHHCCCCCHHHHCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEC
SGAFILGAGTTYVLLPSEKLGIVVLTNAQPTGVPEALAASFMDLAQFGTVTRDWLTAYGP
CCCEEEECCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCH
LIDPLYTPLGTLAGKSAPARPTPAKPLATYVGTYANAYFGEARVSEDKGRLILTVGPKPR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEEEECCCCC
VFTLDHWSGDDFIFRPEGEETAPVGSVSQVTFSDRRMKVEFFNDNGLGTFERR
EEEEECCCCCCEEECCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]