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The map label for this gene is aroE [H]

Identifier: 154245561

GI number: 154245561

Start: 1829712

End: 1830545

Strand: Reverse

Name: aroE [H]

Synonym: Xaut_1616

Alternate gene names: 154245561

Gene position: 1830545-1829712 (Counterclockwise)

Preceding gene: 154245562

Following gene: 154245560

Centisome position: 34.48

GC content: 69.9

Gene sequence:

>834_bases
ATGACCACACCCCAGCCCACCCGCGAGATCACCGGCCACACCCGCGTCTACGGCATCCTCGCCGACCCCATCCATCACGT
GAAGACGCCGCAGATGCTCAACGCGCTGATGGCGCGCGAGGGCCGCGACGGGGTGATGGTGCCGTTCCAGGTCGCCCCGG
ACGACCTCGCGACGCTGGTCGCGGGCCTCAAGACCATGAAGAGCCTCGGCGGCTTCGTGGTGACGGTGCCGCACAAGACC
GCCATCGTGGACCTGTGCGACGCCGTCTCCGACAGCGCCCGCCGCATCGGGGCGGTGAACACGGTGCGCCGCGAGGCGGA
CGGCCGGCTCATCGGCGAGATGCTGGACGGCAAGGGCTTCGTCGGCGGCCTGCTGGCGGCGGGCATCGATCCGAAGGACA
AAAGCGTCTACCTCGCCGGCGCCGGCGGGGCGGCCAACGCCATTGCCTTTGCCTTCGTGGAAGCTGGCATCTCCCGCCTC
ACCATCGCCAACCGCACCCGCGCCAAGGCGGAAGACCTCGCCGTCCGCCTCGCCGAGGCCTATCCCAAGGCGCAGGTGGA
CATCGGCAACCCTGACCCCTCCGGCCACGACATCGTGGTGAATGGCACCTCCCTCGGCCTCAAGGACGGCGATGCCCTGC
CGCTCGATACCGCACGCCTGTCGCCGGAGCAGATCGTGGCCGAGGTGATCATGCAACCGGAGGAGACCGCCCTCCTCGCC
GCCGCCAAGGCGAAGGGCTGCCGCATCCATTTCGGCAAGCCCATGCTGGCCTGCCAGCTCGACCTCATGGCCGAGTTCCT
CGGCATGCGCGCGCTCCCGGGAGCCGGCAAGTGA

Upstream 100 bases:

>100_bases
TTGCCCTCGAGAACACCGGCATCGGCCTGCTCGCCGACCCGCACATCAAGACCGCCTACCTCGGCATCTGAGCCTTCGGG
CCACCCCCGGAACCTGCCCC

Downstream 100 bases:

>100_bases
GCGGCCCCGGCACTGGCGCCCTCGCCGGCCGCTGCGCCCTCATCACCGGCGGCGCCTCCGGACTTGGCCTTGCCGTGGCG
CAAGCGTTCCGGGTCGAGGG

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTTPQPTREITGHTRVYGILADPIHHVKTPQMLNALMAREGRDGVMVPFQVAPDDLATLVAGLKTMKSLGGFVVTVPHKT
AIVDLCDAVSDSARRIGAVNTVRREADGRLIGEMLDGKGFVGGLLAAGIDPKDKSVYLAGAGGAANAIAFAFVEAGISRL
TIANRTRAKAEDLAVRLAEAYPKAQVDIGNPDPSGHDIVVNGTSLGLKDGDALPLDTARLSPEQIVAEVIMQPEETALLA
AAKAKGCRIHFGKPMLACQLDLMAEFLGMRALPGAGK

Sequences:

>Translated_277_residues
MTTPQPTREITGHTRVYGILADPIHHVKTPQMLNALMAREGRDGVMVPFQVAPDDLATLVAGLKTMKSLGGFVVTVPHKT
AIVDLCDAVSDSARRIGAVNTVRREADGRLIGEMLDGKGFVGGLLAAGIDPKDKSVYLAGAGGAANAIAFAFVEAGISRL
TIANRTRAKAEDLAVRLAEAYPKAQVDIGNPDPSGHDIVVNGTSLGLKDGDALPLDTARLSPEQIVAEVIMQPEETALLA
AAKAKGCRIHFGKPMLACQLDLMAEFLGMRALPGAGK
>Mature_276_residues
TTPQPTREITGHTRVYGILADPIHHVKTPQMLNALMAREGRDGVMVPFQVAPDDLATLVAGLKTMKSLGGFVVTVPHKTA
IVDLCDAVSDSARRIGAVNTVRREADGRLIGEMLDGKGFVGGLLAAGIDPKDKSVYLAGAGGAANAIAFAFVEAGISRLT
IANRTRAKAEDLAVRLAEAYPKAQVDIGNPDPSGHDIVVNGTSLGLKDGDALPLDTARLSPEQIVAEVIMQPEETALLAA
AKAKGCRIHFGKPMLACQLDLMAEFLGMRALPGAGK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=264, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789675, Length=239, Percent_Identity=28.0334728033473, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29006; Mature: 28875

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQPTREITGHTRVYGILADPIHHVKTPQMLNALMAREGRDGVMVPFQVAPDDLATLV
CCCCCCCHHHCCCEEEEEEECCCHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
AGLKTMKSLGGFVVTVPHKTAIVDLCDAVSDSARRIGAVNTVRREADGRLIGEMLDGKGF
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCH
VGGLLAAGIDPKDKSVYLAGAGGAANAIAFAFVEAGISRLTIANRTRAKAEDLAVRLAEA
HHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHEEECCCHHHHHHHHHHHHHHH
YPKAQVDIGNPDPSGHDIVVNGTSLGLKDGDALPLDTARLSPEQIVAEVIMQPEETALLA
CCCCEEECCCCCCCCCEEEEECCEECCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHH
AAKAKGCRIHFGKPMLACQLDLMAEFLGMRALPGAGK
HHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTPQPTREITGHTRVYGILADPIHHVKTPQMLNALMAREGRDGVMVPFQVAPDDLATLV
CCCCCCHHHCCCEEEEEEECCCHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHH
AGLKTMKSLGGFVVTVPHKTAIVDLCDAVSDSARRIGAVNTVRREADGRLIGEMLDGKGF
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCH
VGGLLAAGIDPKDKSVYLAGAGGAANAIAFAFVEAGISRLTIANRTRAKAEDLAVRLAEA
HHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHEEECCCHHHHHHHHHHHHHHH
YPKAQVDIGNPDPSGHDIVVNGTSLGLKDGDALPLDTARLSPEQIVAEVIMQPEETALLA
CCCCEEECCCCCCCCCEEEEECCEECCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHHH
AAKAKGCRIHFGKPMLACQLDLMAEFLGMRALPGAGK
HHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]