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The map label for this gene is entA [H]

Identifier: 154245538

GI number: 154245538

Start: 1803255

End: 1803965

Strand: Direct

Name: entA [H]

Synonym: Xaut_1592

Alternate gene names: 154245538

Gene position: 1803255-1803965 (Clockwise)

Preceding gene: 154245536

Following gene: 154245542

Centisome position: 33.97

GC content: 72.57

Gene sequence:

>711_bases
ATGGCACTCGACCTGACAGGCAAGCGCGTTCTGATCGTTGGTGCGGGCGGCGGCATCGGCGCGGCCACCGCGCGGGCCTT
TGCTGATGCCGGCGCCCACGTGTTCGCCGCCGGCCGGCCGGGGCCGAAGCTGGACGCCGTCGCGACCGGGACCGGCGGCG
TGGCGGTGGCCCTCGACATTCTCGACGATGGTGCCATCGAACGCGTCTTCGCGGAGGCGCCGGCCTTCGACCACGTCGCC
ATCGCGGCCGCTGCGACCAAGAGTGGCCCGGTCTCCGGCCTGCCTCTGGAGGCCGCGAAGGCCTCCATGGAGAGCAAGTT
CTGGGGCGCCTACCGCGTCGCCCGCGCGGCGCAGGTGGCGGATGGAGGCTCCATCACCTTCGTATCCGGCTTCCTCTCCC
ACCGGCCGAGCGCGGGCGCGGTGCTGCAGGGCGCGATCAACGCCGCGATCGAGGCGCTCGCCCGCGGCCTGGCGCTCGAG
CGGGCGCCAGTGCGCGTCAATACCGTCTCGCCCGGACTTATCGACACGCCGCTGTGGCAGGGCATGCGGGAGGATGACCG
CGCGGCCATGTTCGCTCGCACCGCCGAGCGTCTGCCCGCCCGCCGTGTGGGGCGGCCGGAGGACATCGCACAGGCGATCC
TCTTCGTCGCCACCAACCCGTTCGTCACCGGCACGACCGTCACGGTCGATGGTGGCGGCACCATTGCGTGA

Upstream 100 bases:

>100_bases
GCTCGCTTATCAGCTTCAGAACAAGAGCGCACATTGCCCTCATGGCGAATTGGACTTTCCCGGCTGCGGCAGGCCGGAGA
CGAGGACAGGAGGTCTCATC

Downstream 100 bases:

>100_bases
GGTCGGCATGCCGGACTCGGTACGCCATGCGGTGTCACTGGCCGCCGTCTGATGCCGGCGGTTTCGTCCTCTCCGTGGCG
CCGCCCGCGCGGGCGGGTCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MALDLTGKRVLIVGAGGGIGAATARAFADAGAHVFAAGRPGPKLDAVATGTGGVAVALDILDDGAIERVFAEAPAFDHVA
IAAAATKSGPVSGLPLEAAKASMESKFWGAYRVARAAQVADGGSITFVSGFLSHRPSAGAVLQGAINAAIEALARGLALE
RAPVRVNTVSPGLIDTPLWQGMREDDRAAMFARTAERLPARRVGRPEDIAQAILFVATNPFVTGTTVTVDGGGTIA

Sequences:

>Translated_236_residues
MALDLTGKRVLIVGAGGGIGAATARAFADAGAHVFAAGRPGPKLDAVATGTGGVAVALDILDDGAIERVFAEAPAFDHVA
IAAAATKSGPVSGLPLEAAKASMESKFWGAYRVARAAQVADGGSITFVSGFLSHRPSAGAVLQGAINAAIEALARGLALE
RAPVRVNTVSPGLIDTPLWQGMREDDRAAMFARTAERLPARRVGRPEDIAQAILFVATNPFVTGTTVTVDGGGTIA
>Mature_235_residues
ALDLTGKRVLIVGAGGGIGAATARAFADAGAHVFAAGRPGPKLDAVATGTGGVAVALDILDDGAIERVFAEAPAFDHVAI
AAAATKSGPVSGLPLEAAKASMESKFWGAYRVARAAQVADGGSITFVSGFLSHRPSAGAVLQGAINAAIEALARGLALER
APVRVNTVSPGLIDTPLWQGMREDDRAAMFARTAERLPARRVGRPEDIAQAILFVATNPFVTGTTVTVDGGGTIA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=30.5785123966942, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=31.3492063492063, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=24.8927038626609, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=28.6290322580645, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.8039215686275, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=31.4516129032258, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=31.9672131147541, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=31.0204081632653, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=29.7959183673469, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.0992366412214, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.2030651340996, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=26.4, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.1960784313725, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=27.0161290322581, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=31.2252964426877, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR003560
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.28 [H]

Molecular weight: Translated: 23808; Mature: 23677

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDLTGKRVLIVGAGGGIGAATARAFADAGAHVFAAGRPGPKLDAVATGTGGVAVALDI
CCEECCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCEEEEEEE
LDDGAIERVFAEAPAFDHVAIAAAATKSGPVSGLPLEAAKASMESKFWGAYRVARAAQVA
CCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DGGSITFVSGFLSHRPSAGAVLQGAINAAIEALARGLALERAPVRVNTVSPGLIDTPLWQ
CCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHC
GMREDDRAAMFARTAERLPARRVGRPEDIAQAILFVATNPFVTGTTVTVDGGGTIA
CCCCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCEEECEEEEECCCCCCC
>Mature Secondary Structure 
ALDLTGKRVLIVGAGGGIGAATARAFADAGAHVFAAGRPGPKLDAVATGTGGVAVALDI
CEECCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCEEEEEEE
LDDGAIERVFAEAPAFDHVAIAAAATKSGPVSGLPLEAAKASMESKFWGAYRVARAAQVA
CCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DGGSITFVSGFLSHRPSAGAVLQGAINAAIEALARGLALERAPVRVNTVSPGLIDTPLWQ
CCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHC
GMREDDRAAMFARTAERLPARRVGRPEDIAQAILFVATNPFVTGTTVTVDGGGTIA
CCCCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2521622; 2521621; 9278503 [H]