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The map label for this gene is mdtA [H]

Identifier: 154245542

GI number: 154245542

Start: 1805829

End: 1807025

Strand: Direct

Name: mdtA [H]

Synonym: Xaut_1596

Alternate gene names: 154245542

Gene position: 1805829-1807025 (Clockwise)

Preceding gene: 154245538

Following gene: 154245543

Centisome position: 34.01

GC content: 69.42

Gene sequence:

>1197_bases
ATGCGGCCTGTCTTATGGATCGTGACGCCGGCGGTGATCCTCGCCGGCGCCGTCACGTGGCATTTCGGGCTGCTGACGCC
CGGCCCGGACGCCCCCAAGGCGAAGGCTGTCGCCCCACCCATTCCGGTGGTGGCGGATACGGTGCGGCTTCAGGACGTGC
CCATCTACGCCCTCGGCATCGGCACGGTGCAGGCCTCCAACACCATCGTGGTGAAGGTGCGCGTCGACGGCGAATTGCAG
AAGGTCGCCTTCACCGAGGGACAGGACGTGAAGGCGGGTGACCTGCTCGCGCAGATCGATCCGCGCCCGTTCACGGCGGC
GCTCAACCAGGCCAGGGCGGCCAAGGCCAAGGACGAGGCCCTGCTCGCCAACGCCAAGATGGATTACGAGCGCTACAAGA
CCCTTGTTCCCAAGCAGGCCGCATCCCAACAGCAGCTCGATACCCAGTCGGCGCTTGTGGCCCAGTACCAGGCGGCGGTG
GAGGGCGATCAGGCCGCCATCGACAATGCCCAGGTGCAGCTCGACTATGCCACCATCCGCGCGCCCATTTCCGGGCGGAC
CGGCGTGCGGCTCGTGGACCAGGGCAACATCGTCCACGCCTCCGACACCGGCGGGCTGGTGGTGATTACCCAGGTGAAGC
CGGTCGCCGTGCTGTTCGCCCTGCCGCAGGACCGGTTGGAGGACGTGCGCGAGGCGATGGCGCGCGGGCCGGTGGAGGTG
ATCGCCCTGAAGCGGGACGGCACCACGCAGATGGGCCAAGGCCAGATCCAGTTGATCGACAACCAGATCAGCTCCGATAC
CGGCACCCTGCGTCTCAAGGCGCTGTTCCCCAACGACGACCTGAAGCTCTGGCCCGGCGCCTTCGTCAACGTGAAGGTGC
TGGTGGACACCCGCCGCGCGGTGGCGACGGTTCCCGCGCAGGCGATCCAGCGCAGCCCCGACGGGTTCTATGTCTATCGG
GTGAAGGCCGACGACACCGTGGAGCAGCGCCCCGTGAAGGTGGGCGGCACCCGCGACGGCGTCTCCTTCCTTGAGGCCGG
CCTCACCGCCGGCGACCGGGTGGTGGTGGACGGCCAGTACAAGCTGACGCCGGGCGCCCGGGTCTCGGCGCGGCAGGCGC
CGGCCGGCACGCCCGGAACCGATGGCGCACCCGGCGGTGGAACGCTCACCAGCGCCAGCGCGGAGAGCCCGGCATGA

Upstream 100 bases:

>100_bases
CGTTGATGCGATCACAGTCCCGTGAGCCTGGACGCATGGCCGCAGGGTTCCGTCCGCCGGCGGGTTGAAAGGCCCGTTGA
CCACTGGAGCGCAAGAGCTG

Downstream 100 bases:

>100_bases
ATATCTCCGCTCCTTTCATCCATCGCCCCATCGCCACCACGTTGCTGATGGCGGCCCTCGTCCTCGTGGGCGCTGTGGCC
TATGCCATGCTGCCGGTGGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRPVLWIVTPAVILAGAVTWHFGLLTPGPDAPKAKAVAPPIPVVADTVRLQDVPIYALGIGTVQASNTIVVKVRVDGELQ
KVAFTEGQDVKAGDLLAQIDPRPFTAALNQARAAKAKDEALLANAKMDYERYKTLVPKQAASQQQLDTQSALVAQYQAAV
EGDQAAIDNAQVQLDYATIRAPISGRTGVRLVDQGNIVHASDTGGLVVITQVKPVAVLFALPQDRLEDVREAMARGPVEV
IALKRDGTTQMGQGQIQLIDNQISSDTGTLRLKALFPNDDLKLWPGAFVNVKVLVDTRRAVATVPAQAIQRSPDGFYVYR
VKADDTVEQRPVKVGGTRDGVSFLEAGLTAGDRVVVDGQYKLTPGARVSARQAPAGTPGTDGAPGGGTLTSASAESPA

Sequences:

>Translated_398_residues
MRPVLWIVTPAVILAGAVTWHFGLLTPGPDAPKAKAVAPPIPVVADTVRLQDVPIYALGIGTVQASNTIVVKVRVDGELQ
KVAFTEGQDVKAGDLLAQIDPRPFTAALNQARAAKAKDEALLANAKMDYERYKTLVPKQAASQQQLDTQSALVAQYQAAV
EGDQAAIDNAQVQLDYATIRAPISGRTGVRLVDQGNIVHASDTGGLVVITQVKPVAVLFALPQDRLEDVREAMARGPVEV
IALKRDGTTQMGQGQIQLIDNQISSDTGTLRLKALFPNDDLKLWPGAFVNVKVLVDTRRAVATVPAQAIQRSPDGFYVYR
VKADDTVEQRPVKVGGTRDGVSFLEAGLTAGDRVVVDGQYKLTPGARVSARQAPAGTPGTDGAPGGGTLTSASAESPA
>Mature_398_residues
MRPVLWIVTPAVILAGAVTWHFGLLTPGPDAPKAKAVAPPIPVVADTVRLQDVPIYALGIGTVQASNTIVVKVRVDGELQ
KVAFTEGQDVKAGDLLAQIDPRPFTAALNQARAAKAKDEALLANAKMDYERYKTLVPKQAASQQQLDTQSALVAQYQAAV
EGDQAAIDNAQVQLDYATIRAPISGRTGVRLVDQGNIVHASDTGGLVVITQVKPVAVLFALPQDRLEDVREAMARGPVEV
IALKRDGTTQMGQGQIQLIDNQISSDTGTLRLKALFPNDDLKLWPGAFVNVKVLVDTRRAVATVPAQAIQRSPDGFYVYR
VKADDTVEQRPVKVGGTRDGVSFLEAGLTAGDRVVVDGQYKLTPGARVSARQAPAGTPGTDGAPGGGTLTSASAESPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=340, Percent_Identity=42.3529411764706, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1786668, Length=371, Percent_Identity=30.7277628032345, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1789929, Length=319, Percent_Identity=30.0940438871473, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789665, Length=318, Percent_Identity=31.4465408805031, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081796, Length=393, Percent_Identity=27.2264631043257, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081951, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41985; Mature: 41985

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVLWIVTPAVILAGAVTWHFGLLTPGPDAPKAKAVAPPIPVVADTVRLQDVPIYALGI
CCCEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCEEECEEEEECCCEEEEEE
GTVQASNTIVVKVRVDGELQKVAFTEGQDVKAGDLLAQIDPRPFTAALNQARAAKAKDEA
EEEECCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
LLANAKMDYERYKTLVPKQAASQQQLDTQSALVAQYQAAVEGDQAAIDNAQVQLDYATIR
EEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
APISGRTGVRLVDQGNIVHASDTGGLVVITQVKPVAVLFALPQDRLEDVREAMARGPVEV
ECCCCCCCEEEEECCCEEEECCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCEEE
IALKRDGTTQMGQGQIQLIDNQISSDTGTLRLKALFPNDDLKLWPGAFVNVKVLVDTRRA
EEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCEECCCCEEEEEEEEECCHH
VATVPAQAIQRSPDGFYVYRVKADDTVEQRPVKVGGTRDGVSFLEAGLTAGDRVVVDGQY
HHHCCHHHHHCCCCCEEEEEEECCCCHHHCCEEECCCCCCHHHHHHCCCCCCEEEECCEE
KLTPGARVSARQAPAGTPGTDGAPGGGTLTSASAESPA
EECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MRPVLWIVTPAVILAGAVTWHFGLLTPGPDAPKAKAVAPPIPVVADTVRLQDVPIYALGI
CCCEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCEEECEEEEECCCEEEEEE
GTVQASNTIVVKVRVDGELQKVAFTEGQDVKAGDLLAQIDPRPFTAALNQARAAKAKDEA
EEEECCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHH
LLANAKMDYERYKTLVPKQAASQQQLDTQSALVAQYQAAVEGDQAAIDNAQVQLDYATIR
EEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
APISGRTGVRLVDQGNIVHASDTGGLVVITQVKPVAVLFALPQDRLEDVREAMARGPVEV
ECCCCCCCEEEEECCCEEEECCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCEEE
IALKRDGTTQMGQGQIQLIDNQISSDTGTLRLKALFPNDDLKLWPGAFVNVKVLVDTRRA
EEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCEECCCCEEEEEEEEECCHH
VATVPAQAIQRSPDGFYVYRVKADDTVEQRPVKVGGTRDGVSFLEAGLTAGDRVVVDGQY
HHHCCHHHHHCCCCCEEEEEEECCCCHHHCCEEECCCCCCHHHHHHCCCCCCEEEECCEE
KLTPGARVSARQAPAGTPGTDGAPGGGTLTSASAESPA
EECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA