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The map label for this gene is glsA2 [H]

Identifier: 154245497

GI number: 154245497

Start: 1761186

End: 1763027

Strand: Reverse

Name: glsA2 [H]

Synonym: Xaut_1550

Alternate gene names: 154245497

Gene position: 1763027-1761186 (Counterclockwise)

Preceding gene: 154245502

Following gene: 154245495

Centisome position: 33.21

GC content: 68.24

Gene sequence:

>1842_bases
GTGCCGAATTTCCTGCCCCTTGCCACGACGCCCCTCGAAACACCGCTGCTGCGCGCCATCCGGGATATCCACACCCGCTT
CACGCCCCTGCATGACGGCGAGGTCGCCTCCTACATCCCGGAACTGGGCAAGGCCGACCCGGACCATTTCGGGATCGCCG
TGGCCACCACCGACGGCCATGTCTATGAAGCGGGCGACACGGCCGTGCCGTTCACCATCCAGTCGGTGTCCAAGGCCATC
GTCTACGCCCTCGCCCTCGACATGCTGGGGTCCGAGAAGGTGGAGGCAGCCATCGGCGTGGAGCCGAGCGGCGAGGCCTT
CAATTCCATCCGCCTGAAGGCCGACAACCGCCCCTTCAACGCCATGGTGAATGCCGGCGCCATCTGCTGCAGCGGGCTTC
TCGCCGAGGCTGCCGGCGACGAGGCCTTCGAGCTGATCCGCACCACGCTCAGCCGCTTTGCCGGGCGCGAGCTGGAGGTG
GACGATGCGGTGTTCCAGTCGGAGCGCCAGACCGGCGACCGCAACCGCGCCATCGCCTACCTGCTGCGCACCTATGGCGG
CGTGCGGGGCGACGTGGATCACATCCTCGACACCTATTTCCGCCAGTGCTCGGTTCTGGTCACCGCCCGCGACCTGGCGG
TGATGGGGGCGAGCTTCGCCAATCACGGGGTCAATCCGGTGACCGGGGAGATGGTGGCCTCAAACTACGCCGTGGCGCGC
ACCCTGGCGGTGATGATCTCCTCCGGCATGTATGACTTTGCCGGCGAGTGGATCTATCGGGTGGGCGTGCCGGCCAAGAG
CGGCGTCGGTGGCGGCATTCTCGCCGCTTTGCCCTCCCAGCTGGGCCTCGGCATCTTCTCGCCCCGGCTCGATGCCCATG
GCAACAGCGTGCGCGGCCTGCGCACCTGCTCCGCCCTCTCCGACGCCTTCGACCTGCACATGCTGTCGCGGCGCGACGAC
GTGCGCACCTGCATCGCCGCCGACTACGATTTCCGCACCGTGCCCTCCAAGCCCGGGCGCCAGCCCCACGAGCAGAGCAT
CCTGGAACAGCGCTCCGGCTCCATCCGCGTGCTGGAACTGGCCGGCAAGCTCTCCTTCGCCACCATGGATTATGTGACCC
GCCGGCTCACCGATCCCGCAGGCGTGCCGGCCTTCCTGATCCTCAACCTGCACCGGGTCTCCACCATCACCGATGCGGGG
CTGCGCCTGTTCACCGGCCTGATCCGCAATCAGCTTCCGGCCTCCACCACCACGGTGATCGCCGGAGTTGAAGGCAACTC
GCCGGTGGCGCCGCAGGTCAAGGCCATGAAGGAGGAAGGCGTGCGCGTGCGCATCTTCCCCACCTACGACGCCGCCGTGG
ACTGGGCCGAGGACCAGATCGTCTACCGCCATGGCGGCTTCTCGCAGATCGGCATCGAAGCCGACCTGTCAGGCCAGGCG
CTGCTCGCCGGGCTGTCGCCGCAGGAACTGGCCGACCTCTCCCGCCTCGGCACCCGCGTGGTGTTCGATGCCGGCACGCG
GATCATCGACGCCAATGAACCGCCGGCCCGGGTCTATTTCCTGGTGCGCGGCATGGTCAGCGTGCGCTCAATGCACGACG
TGCGCCTGTCGACGTTGATCCCGGGCATGGCCTTCGGCGAGCTGGCGCTCATCGATCAGCCGCGCAGTGCCGACGTGTGG
GCCGACACGGAGGCGGTCTGCCTGGAGATTTCCGCCGAGCAGTTCCGCGCCTTCCAGGAGACCCATGCCCGCGCCGCCGA
CCGGATCATGCGCAACCTCGCCATCCTGCTGGCCGGCCGGGTGCGCATGGCCACGGCGCGGATCGACATGCTGACGGGGT
GA

Upstream 100 bases:

>100_bases
CGTGCCGATGGCCGGGAACGGAGCGCGGTTTGCCGCCGCGCACCATTGCCAACCGCAGCGCACGCGCTTTCACTAGGGGA
GAGTCGCCCGGAGCCGCGCT

Downstream 100 bases:

>100_bases
CACCTCGCCGGCACGACGCAGTCCGCCGAGTGGCTCGCCTACGCCACCTCGTCGCTCACCACCTTGAAGGTCGTAAGCGT
CGCCGGGCCGAAGGTGGTGA

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MPNFLPLATTPLETPLLRAIRDIHTRFTPLHDGEVASYIPELGKADPDHFGIAVATTDGHVYEAGDTAVPFTIQSVSKAI
VYALALDMLGSEKVEAAIGVEPSGEAFNSIRLKADNRPFNAMVNAGAICCSGLLAEAAGDEAFELIRTTLSRFAGRELEV
DDAVFQSERQTGDRNRAIAYLLRTYGGVRGDVDHILDTYFRQCSVLVTARDLAVMGASFANHGVNPVTGEMVASNYAVAR
TLAVMISSGMYDFAGEWIYRVGVPAKSGVGGGILAALPSQLGLGIFSPRLDAHGNSVRGLRTCSALSDAFDLHMLSRRDD
VRTCIAADYDFRTVPSKPGRQPHEQSILEQRSGSIRVLELAGKLSFATMDYVTRRLTDPAGVPAFLILNLHRVSTITDAG
LRLFTGLIRNQLPASTTTVIAGVEGNSPVAPQVKAMKEEGVRVRIFPTYDAAVDWAEDQIVYRHGGFSQIGIEADLSGQA
LLAGLSPQELADLSRLGTRVVFDAGTRIIDANEPPARVYFLVRGMVSVRSMHDVRLSTLIPGMAFGELALIDQPRSADVW
ADTEAVCLEISAEQFRAFQETHARAADRIMRNLAILLAGRVRMATARIDMLTG

Sequences:

>Translated_613_residues
MPNFLPLATTPLETPLLRAIRDIHTRFTPLHDGEVASYIPELGKADPDHFGIAVATTDGHVYEAGDTAVPFTIQSVSKAI
VYALALDMLGSEKVEAAIGVEPSGEAFNSIRLKADNRPFNAMVNAGAICCSGLLAEAAGDEAFELIRTTLSRFAGRELEV
DDAVFQSERQTGDRNRAIAYLLRTYGGVRGDVDHILDTYFRQCSVLVTARDLAVMGASFANHGVNPVTGEMVASNYAVAR
TLAVMISSGMYDFAGEWIYRVGVPAKSGVGGGILAALPSQLGLGIFSPRLDAHGNSVRGLRTCSALSDAFDLHMLSRRDD
VRTCIAADYDFRTVPSKPGRQPHEQSILEQRSGSIRVLELAGKLSFATMDYVTRRLTDPAGVPAFLILNLHRVSTITDAG
LRLFTGLIRNQLPASTTTVIAGVEGNSPVAPQVKAMKEEGVRVRIFPTYDAAVDWAEDQIVYRHGGFSQIGIEADLSGQA
LLAGLSPQELADLSRLGTRVVFDAGTRIIDANEPPARVYFLVRGMVSVRSMHDVRLSTLIPGMAFGELALIDQPRSADVW
ADTEAVCLEISAEQFRAFQETHARAADRIMRNLAILLAGRVRMATARIDMLTG
>Mature_612_residues
PNFLPLATTPLETPLLRAIRDIHTRFTPLHDGEVASYIPELGKADPDHFGIAVATTDGHVYEAGDTAVPFTIQSVSKAIV
YALALDMLGSEKVEAAIGVEPSGEAFNSIRLKADNRPFNAMVNAGAICCSGLLAEAAGDEAFELIRTTLSRFAGRELEVD
DAVFQSERQTGDRNRAIAYLLRTYGGVRGDVDHILDTYFRQCSVLVTARDLAVMGASFANHGVNPVTGEMVASNYAVART
LAVMISSGMYDFAGEWIYRVGVPAKSGVGGGILAALPSQLGLGIFSPRLDAHGNSVRGLRTCSALSDAFDLHMLSRRDDV
RTCIAADYDFRTVPSKPGRQPHEQSILEQRSGSIRVLELAGKLSFATMDYVTRRLTDPAGVPAFLILNLHRVSTITDAGL
RLFTGLIRNQLPASTTTVIAGVEGNSPVAPQVKAMKEEGVRVRIFPTYDAAVDWAEDQIVYRHGGFSQIGIEADLSGQAL
LAGLSPQELADLSRLGTRVVFDAGTRIIDANEPPARVYFLVRGMVSVRSMHDVRLSTLIPGMAFGELALIDQPRSADVWA
DTEAVCLEISAEQFRAFQETHARAADRIMRNLAILLAGRVRMATARIDMLTG

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=285, Percent_Identity=45.6140350877193, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI20336214, Length=296, Percent_Identity=42.9054054054054, Blast_Score=244, Evalue=2e-64,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=39.2739273927393, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787804, Length=297, Percent_Identity=35.3535353535354, Blast_Score=175, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=287, Percent_Identity=40.418118466899, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17532727, Length=299, Percent_Identity=38.7959866220736, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193204073, Length=295, Percent_Identity=37.6271186440678, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI193204075, Length=297, Percent_Identity=37.3737373737374, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI281363239, Length=320, Percent_Identity=38.125, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI281363241, Length=320, Percent_Identity=38.125, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24653162, Length=320, Percent_Identity=38.125, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24653158, Length=326, Percent_Identity=38.0368098159509, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653156, Length=326, Percent_Identity=38.0368098159509, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653164, Length=320, Percent_Identity=38.125, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI116008307, Length=326, Percent_Identity=38.0368098159509, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24653166, Length=326, Percent_Identity=38.0368098159509, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR015868
- InterPro:   IPR014710
- InterPro:   IPR002645 [H]

Pfam domain/function: PF00027 cNMP_binding; PF04960 Glutaminase; PF01740 STAS [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 66189; Mature: 66058

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50801 STAS ; PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFLPLATTPLETPLLRAIRDIHTRFTPLHDGEVASYIPELGKADPDHFGIAVATTDGH
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCE
VYEAGDTAVPFTIQSVSKAIVYALALDMLGSEKVEAAIGVEPSGEAFNSIRLKADNRPFN
EEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEEEEECCCCCH
AMVNAGAICCSGLLAEAAGDEAFELIRTTLSRFAGRELEVDDAVFQSERQTGDRNRAIAY
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHH
LLRTYGGVRGDVDHILDTYFRQCSVLVTARDLAVMGASFANHGVNPVTGEMVASNYAVAR
HHHHHCCCCCCHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TLAVMISSGMYDFAGEWIYRVGVPAKSGVGGGILAALPSQLGLGIFSPRLDAHGNSVRGL
HHHHHHHCCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
RTCSALSDAFDLHMLSRRDDVRTCIAADYDFRTVPSKPGRQPHEQSILEQRSGSIRVLEL
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
AGKLSFATMDYVTRRLTDPAGVPAFLILNLHRVSTITDAGLRLFTGLIRNQLPASTTTVI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AGVEGNSPVAPQVKAMKEEGVRVRIFPTYDAAVDWAEDQIVYRHGGFSQIGIEADLSGQA
EECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHCCCCCEEEEECCCCCEECEEECCCCCE
LLAGLSPQELADLSRLGTRVVFDAGTRIIDANEPPARVYFLVRGMVSVRSMHDVRLSTLI
EEECCCHHHHHHHHHCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGMAFGELALIDQPRSADVWADTEAVCLEISAEQFRAFQETHARAADRIMRNLAILLAGR
CCCCCCCEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
VRMATARIDMLTG
HHEEHHHEEECCC
>Mature Secondary Structure 
PNFLPLATTPLETPLLRAIRDIHTRFTPLHDGEVASYIPELGKADPDHFGIAVATTDGH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCE
VYEAGDTAVPFTIQSVSKAIVYALALDMLGSEKVEAAIGVEPSGEAFNSIRLKADNRPFN
EEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEEEEECCCCCH
AMVNAGAICCSGLLAEAAGDEAFELIRTTLSRFAGRELEVDDAVFQSERQTGDRNRAIAY
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHH
LLRTYGGVRGDVDHILDTYFRQCSVLVTARDLAVMGASFANHGVNPVTGEMVASNYAVAR
HHHHHCCCCCCHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TLAVMISSGMYDFAGEWIYRVGVPAKSGVGGGILAALPSQLGLGIFSPRLDAHGNSVRGL
HHHHHHHCCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
RTCSALSDAFDLHMLSRRDDVRTCIAADYDFRTVPSKPGRQPHEQSILEQRSGSIRVLEL
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
AGKLSFATMDYVTRRLTDPAGVPAFLILNLHRVSTITDAGLRLFTGLIRNQLPASTTTVI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AGVEGNSPVAPQVKAMKEEGVRVRIFPTYDAAVDWAEDQIVYRHGGFSQIGIEADLSGQA
EECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHCCCCCEEEEECCCCCEECEEECCCCCE
LLAGLSPQELADLSRLGTRVVFDAGTRIIDANEPPARVYFLVRGMVSVRSMHDVRLSTLI
EEECCCHHHHHHHHHCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PGMAFGELALIDQPRSADVWADTEAVCLEISAEQFRAFQETHARAADRIMRNLAILLAGR
CCCCCCCEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
VRMATARIDMLTG
HHEEHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]