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The map label for this gene is tag [H]

Identifier: 154245364

GI number: 154245364

Start: 1620874

End: 1621545

Strand: Direct

Name: tag [H]

Synonym: Xaut_1417

Alternate gene names: 154245364

Gene position: 1620874-1621545 (Clockwise)

Preceding gene: 154245363

Following gene: 154245365

Centisome position: 30.53

GC content: 68.01

Gene sequence:

>672_bases
ATGGCGGAGCCGAAGGCGGGAAACGCGAACAAGAGTGCGCCGGAGGCGGAAAGCGCGAACGGGATCGATCTGGCGGTGAA
GGCGGAACGCGCGCCGCTGCTCCAGCACGGGGATGGGCGGGCGCGCTGCTTCTGGTGCGGCACCGACCCGTTCTACATGG
CCTATCACGACGACGAATGGGGCGTGCCCGAGCGCGACAGTCGCGCCCTGTTCGAGAAGCTGCTGCTGGATGGATTCCAG
GCCGGCCTCTCGTGGATCACCATCCTGCGGAAGCGGGAGAATTTCCGCCGGGCCTTCGACGGCTTCGATCCCGAGACGAT
GGCCCGCTACGACGCAGCCAAGGTGGAGGCCCTCATGGCCGACGCCGGCATCGTGCGCAACCGGGCCAAGGTGGAGGGGG
CGGTTGCCTCCGCCCGCGCCTATCTCGACCTCCAGGACAAGGGCATCGCCTTTTCCGACCTGATGTGGGAGGCGGTGGAC
GGCGAGACGCGGGTGAACCGGCCGAAGCGCATCGCCGACGTGCCGGCGCAGACGGCACAGTCCGTCGCCTTGTCCAAGCG
GTTGAAGGGACTGGGCTTCAAGTTCGTCGGTCCCACCATCGTCTATGCCGCCATGCAGGCCTGCGGGCTGGTGGACGACC
ACCTCGCCGGTTGTCACTGCGCCAGGCCCTAG

Upstream 100 bases:

>100_bases
CGGTGGAGCTGCGCCGTCCCGATTGGGCCGTCTTTTCCATGGAGTGGGAAAAGAAGGTGAGCGAGCTGGACCGCAAGTTC
AAGGGAAGCTGAGAGGGGCG

Downstream 100 bases:

>100_bases
GCTGCCGCGACAATGGGTCGGGGATGGCGGCGGACTTTGTGGCACGCGCCCCTTTCATCGCCGGCGGGCGACGCCTATAT
TCGTTCTGCCGACGCAAGTC

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MAEPKAGNANKSAPEAESANGIDLAVKAERAPLLQHGDGRARCFWCGTDPFYMAYHDDEWGVPERDSRALFEKLLLDGFQ
AGLSWITILRKRENFRRAFDGFDPETMARYDAAKVEALMADAGIVRNRAKVEGAVASARAYLDLQDKGIAFSDLMWEAVD
GETRVNRPKRIADVPAQTAQSVALSKRLKGLGFKFVGPTIVYAAMQACGLVDDHLAGCHCARP

Sequences:

>Translated_223_residues
MAEPKAGNANKSAPEAESANGIDLAVKAERAPLLQHGDGRARCFWCGTDPFYMAYHDDEWGVPERDSRALFEKLLLDGFQ
AGLSWITILRKRENFRRAFDGFDPETMARYDAAKVEALMADAGIVRNRAKVEGAVASARAYLDLQDKGIAFSDLMWEAVD
GETRVNRPKRIADVPAQTAQSVALSKRLKGLGFKFVGPTIVYAAMQACGLVDDHLAGCHCARP
>Mature_222_residues
AEPKAGNANKSAPEAESANGIDLAVKAERAPLLQHGDGRARCFWCGTDPFYMAYHDDEWGVPERDSRALFEKLLLDGFQA
GLSWITILRKRENFRRAFDGFDPETMARYDAAKVEALMADAGIVRNRAKVEGAVASARAYLDLQDKGIAFSDLMWEAVDG
ETRVNRPKRIADVPAQTAQSVALSKRLKGLGFKFVGPTIVYAAMQACGLVDDHLAGCHCARP

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=179, Percent_Identity=51.9553072625698, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 24433; Mature: 24302

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPKAGNANKSAPEAESANGIDLAVKAERAPLLQHGDGRARCFWCGTDPFYMAYHDDEW
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCCCEEEEEECCCCEEEEEECCCC
GVPERDSRALFEKLLLDGFQAGLSWITILRKRENFRRAFDGFDPETMARYDAAKVEALMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DAGIVRNRAKVEGAVASARAYLDLQDKGIAFSDLMWEAVDGETRVNRPKRIADVPAQTAQ
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCHHHHH
SVALSKRLKGLGFKFVGPTIVYAAMQACGLVDDHLAGCHCARP
HHHHHHHHHHCCEEHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure 
AEPKAGNANKSAPEAESANGIDLAVKAERAPLLQHGDGRARCFWCGTDPFYMAYHDDEW
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCCCEEEEEECCCCEEEEEECCCC
GVPERDSRALFEKLLLDGFQAGLSWITILRKRENFRRAFDGFDPETMARYDAAKVEALMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DAGIVRNRAKVEGAVASARAYLDLQDKGIAFSDLMWEAVDGETRVNRPKRIADVPAQTAQ
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHCCHHHHH
SVALSKRLKGLGFKFVGPTIVYAAMQACGLVDDHLAGCHCARP
HHHHHHHHHHCCEEHHHHHHHHHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]