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The map label for this gene is qseC [H]

Identifier: 154245229

GI number: 154245229

Start: 1474158

End: 1475507

Strand: Direct

Name: qseC [H]

Synonym: Xaut_1281

Alternate gene names: 154245229

Gene position: 1474158-1475507 (Clockwise)

Preceding gene: 154245228

Following gene: 154245236

Centisome position: 27.77

GC content: 69.33

Gene sequence:

>1350_bases
GTGAAGCGGCTGGTCCGGGGGCTGTTCGGCCGCCTGATGATCGGCATGGTGGCGGTGAGCGTGGTGGCAGTCTGCGTCAC
CGCCGTGTTCCTCTATATCCGCTTCGACACCATCAACACCCGCTTCCGCGAGGGCACGCTCCACAGCTTCGCCATGAGCA
TCGCCAAGGACGTGCGGGCGGTGGGCCATGTGGTCACCGCGCCCATCCGCCAGTCCACGGTGCATCGCATCGCCCAGGAG
GGCGGCCATTTCATCGTCATCGGCCCGTCCGGCGAACGGCTGGCCGGCTCCGCCGACGTGCACGACCCGTTCGTGCCGGT
GGAGGAGATGGCGGAGCATTATTTCGAGCTGCCCAAGGGCAATTCGCCGGAAGCGCTCTACGGCATTTCCCTGCGCATCC
ACGGCATCGCCCAGCCCACCTATGTGCAGGTGGCCTTTCCCAGCAGCGACGTGGTGTTTGATTCCGTCCTTGAGGAATTC
ATGCAGGACATCGCCTGGCTGTGGATCCCCTTCATGCTGCTGATGCTGGCGACCAACCTCCTCGTCGCCCGCATCGCGCT
GCGACCCCTCAGCCAGACGGTGGAGGAGGCGGAGGCGATCCAGCCCGGCGGGGTCTCGGTCACTCTCAGTGAGAAGGGGC
TGCCGGACGACGTGCTGGCGCTGGTGCGCGCGGTCAACCAGGCCCTCGGCCGGCTGCGGCAGGGCTATCGCGCCCAGGAG
GAGTTCGTGGGCGACATGGCCCACGAGTTGCGCACGCCGCTGGCGGTGATGAAGACCCAGCTCGCCGTCACCGACGAGCC
TTACGCGCGGGTGCTGGAAAAGGAACTCGTCGCCATGGAGCGGCTGGTGGAGCAATTGCTCGACCGGGTCCGGCTCGGCC
GCTTCCGCATCGAGCCCGGCGACGTGGTGGAGCTGCGCGAGGCGGCGCGGGAGGCCGCCGCCTATCTGGCGCCGCAGGTG
ATCGCCCGCAACCGCTCCATCGAGGTGATCGCGGGTCCGGCGCCCGTGGTGGTGGCCGGCGGCCGCGACGACGTGTTCCG
CGCGGTGCGCAACCTCATCGAGAATGCGCTGGACCACACCCCGGAGGCCACCACCATCAGCGTGGAGGTGACGGACGCCC
CCGCCATCCGGGTGCGCGACCACGGGCCGGGCTTTCCGGCCGAGGTGCTGGACGCCGAGCGCCGGCGCCGCGGCCTGGTG
CGCAGCGATCGCCGCAACGGCGTGGGTCTGGGCCTCGCCATCGTCGAGCGCACCATGATGGTTCATGGCGGCCGGCTGGA
ACTCTCCAACGGCATCGTGGGCGGCTGCGCGGAAATGTGCTTCCCGCCCCTCGGCACCGAGGTGGGTTGA

Upstream 100 bases:

>100_bases
TGCTGATCCACCGCCTGCGCAAGAAGCTGGCGGGGGCCGGCGCGGTGGTGGAGATCCACACTCTGCGCGGCATCGGCTAC
CTCCTGTCCGGGGCGCGGCC

Downstream 100 bases:

>100_bases
GATCGCCCCTCAGCGCCGGGCGGTGGCGATGAGGCCCTTGACCCCCAGGGGTAGGTCGAGGGCGCGGATCATCACCCGTG
CCGGCTCGAAGCCGCCACCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKRLVRGLFGRLMIGMVAVSVVAVCVTAVFLYIRFDTINTRFREGTLHSFAMSIAKDVRAVGHVVTAPIRQSTVHRIAQE
GGHFIVIGPSGERLAGSADVHDPFVPVEEMAEHYFELPKGNSPEALYGISLRIHGIAQPTYVQVAFPSSDVVFDSVLEEF
MQDIAWLWIPFMLLMLATNLLVARIALRPLSQTVEEAEAIQPGGVSVTLSEKGLPDDVLALVRAVNQALGRLRQGYRAQE
EFVGDMAHELRTPLAVMKTQLAVTDEPYARVLEKELVAMERLVEQLLDRVRLGRFRIEPGDVVELREAAREAAAYLAPQV
IARNRSIEVIAGPAPVVVAGGRDDVFRAVRNLIENALDHTPEATTISVEVTDAPAIRVRDHGPGFPAEVLDAERRRRGLV
RSDRRNGVGLGLAIVERTMMVHGGRLELSNGIVGGCAEMCFPPLGTEVG

Sequences:

>Translated_449_residues
MKRLVRGLFGRLMIGMVAVSVVAVCVTAVFLYIRFDTINTRFREGTLHSFAMSIAKDVRAVGHVVTAPIRQSTVHRIAQE
GGHFIVIGPSGERLAGSADVHDPFVPVEEMAEHYFELPKGNSPEALYGISLRIHGIAQPTYVQVAFPSSDVVFDSVLEEF
MQDIAWLWIPFMLLMLATNLLVARIALRPLSQTVEEAEAIQPGGVSVTLSEKGLPDDVLALVRAVNQALGRLRQGYRAQE
EFVGDMAHELRTPLAVMKTQLAVTDEPYARVLEKELVAMERLVEQLLDRVRLGRFRIEPGDVVELREAAREAAAYLAPQV
IARNRSIEVIAGPAPVVVAGGRDDVFRAVRNLIENALDHTPEATTISVEVTDAPAIRVRDHGPGFPAEVLDAERRRRGLV
RSDRRNGVGLGLAIVERTMMVHGGRLELSNGIVGGCAEMCFPPLGTEVG
>Mature_449_residues
MKRLVRGLFGRLMIGMVAVSVVAVCVTAVFLYIRFDTINTRFREGTLHSFAMSIAKDVRAVGHVVTAPIRQSTVHRIAQE
GGHFIVIGPSGERLAGSADVHDPFVPVEEMAEHYFELPKGNSPEALYGISLRIHGIAQPTYVQVAFPSSDVVFDSVLEEF
MQDIAWLWIPFMLLMLATNLLVARIALRPLSQTVEEAEAIQPGGVSVTLSEKGLPDDVLALVRAVNQALGRLRQGYRAQE
EFVGDMAHELRTPLAVMKTQLAVTDEPYARVLEKELVAMERLVEQLLDRVRLGRFRIEPGDVVELREAAREAAAYLAPQV
IARNRSIEVIAGPAPVVVAGGRDDVFRAVRNLIENALDHTPEATTISVEVTDAPAIRVRDHGPGFPAEVLDAERRRRGLV
RSDRRNGVGLGLAIVERTMMVHGGRLELSNGIVGGCAEMCFPPLGTEVG

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=28.8194444444444, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=29.7297297297297, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=288, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=28.2786885245902, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=276, Percent_Identity=24.6376811594203, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=24.2753623188406, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=30.2904564315353, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49151; Mature: 49151

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLVRGLFGRLMIGMVAVSVVAVCVTAVFLYIRFDTINTRFREGTLHSFAMSIAKDVRA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
VGHVVTAPIRQSTVHRIAQEGGHFIVIGPSGERLAGSADVHDPFVPVEEMAEHYFELPKG
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
NSPEALYGISLRIHGIAQPTYVQVAFPSSDVVFDSVLEEFMQDIAWLWIPFMLLMLATNL
CCCCEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVARIALRPLSQTVEEAEAIQPGGVSVTLSEKGLPDDVLALVRAVNQALGRLRQGYRAQE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EFVGDMAHELRTPLAVMKTQLAVTDEPYARVLEKELVAMERLVEQLLDRVRLGRFRIEPG
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
DVVELREAAREAAAYLAPQVIARNRSIEVIAGPAPVVVAGGRDDVFRAVRNLIENALDHT
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCC
PEATTISVEVTDAPAIRVRDHGPGFPAEVLDAERRRRGLVRSDRRNGVGLGLAIVERTMM
CCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHH
VHGGRLELSNGIVGGCAEMCFPPLGTEVG
HCCCEEEECCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKRLVRGLFGRLMIGMVAVSVVAVCVTAVFLYIRFDTINTRFREGTLHSFAMSIAKDVRA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
VGHVVTAPIRQSTVHRIAQEGGHFIVIGPSGERLAGSADVHDPFVPVEEMAEHYFELPKG
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
NSPEALYGISLRIHGIAQPTYVQVAFPSSDVVFDSVLEEFMQDIAWLWIPFMLLMLATNL
CCCCEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVARIALRPLSQTVEEAEAIQPGGVSVTLSEKGLPDDVLALVRAVNQALGRLRQGYRAQE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
EFVGDMAHELRTPLAVMKTQLAVTDEPYARVLEKELVAMERLVEQLLDRVRLGRFRIEPG
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
DVVELREAAREAAAYLAPQVIARNRSIEVIAGPAPVVVAGGRDDVFRAVRNLIENALDHT
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCC
PEATTISVEVTDAPAIRVRDHGPGFPAEVLDAERRRRGLVRSDRRNGVGLGLAIVERTMM
CCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHH
VHGGRLELSNGIVGGCAEMCFPPLGTEVG
HCCCEEEECCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]