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The map label for this gene is qseB [H]

Identifier: 154245228

GI number: 154245228

Start: 1473484

End: 1474161

Strand: Direct

Name: qseB [H]

Synonym: Xaut_1280

Alternate gene names: 154245228

Gene position: 1473484-1474161 (Clockwise)

Preceding gene: 154245226

Following gene: 154245229

Centisome position: 27.75

GC content: 68.88

Gene sequence:

>678_bases
ATGCGTATATTGCTTGTCGAAGACAACGAACGGATGTCGGCGCTGGCCGCCGATGCGCTGCGCACGGCGGGCTTCGCCGT
CGATGCCGTCCATGCGGCGGCTGACGCTGAGGAAGCGGTCTCAACCACCCCGTTCGACGCCATAATCCTCGATCTCGGCC
TGCCGGACCGCGACGGCATGGACCTTCTGGACACGCTGCGGCGCAAGGGTGTGGCCCAGCCCATCCTGGTGCTGACCGCC
CGCGACGGCGCGCCCTCGGTCATCGCCGGGCTCAATGGCGGCGCCGACGACTATATGCGCAAGCCCTTCAACGTGGACGA
ACTGATCGCCCGCGTCCGCGCCCTGCTGCGGCGTCCCGGCTCGGCGCTGGGGGTGTCGCTGAAGGAAGGCAATGTGGAGC
TGGACACCATCGCCCGGCAGGCGCGGGTGGATGGGGTGGGGCTCGATCTCAGCCGCAAGGAGGCGGCGGCGCTGGAGCTT
TTGATGCGCCGCACCGGCGCGGTCATCTCCAAGCCGGCGCTGGAGGAGACCCTCTACGGCTATGGTGAGGAGGTCAGCTC
AAACGCCGTGGAAGTGCTGATCCACCGCCTGCGCAAGAAGCTGGCGGGGGCCGGCGCGGTGGTGGAGATCCACACTCTGC
GCGGCATCGGCTACCTCCTGTCCGGGGCGCGGCCGTGA

Upstream 100 bases:

>100_bases
GATCTGGATCAAATATGCAGCCGCCATTTTACTGTGCGTCAGCATTGATTTTTGCCACATTCCTGGGCGCAATCCGGTGC
GGGGGCGAGATTTCCGGCGC

Downstream 100 bases:

>100_bases
AGCGGCTGGTCCGGGGGCTGTTCGGCCGCCTGATGATCGGCATGGTGGCGGTGAGCGTGGTGGCAGTCTGCGTCACCGCC
GTGTTCCTCTATATCCGCTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRILLVEDNERMSALAADALRTAGFAVDAVHAAADAEEAVSTTPFDAIILDLGLPDRDGMDLLDTLRRKGVAQPILVLTA
RDGAPSVIAGLNGGADDYMRKPFNVDELIARVRALLRRPGSALGVSLKEGNVELDTIARQARVDGVGLDLSRKEAAALEL
LMRRTGAVISKPALEETLYGYGEEVSSNAVEVLIHRLRKKLAGAGAVVEIHTLRGIGYLLSGARP

Sequences:

>Translated_225_residues
MRILLVEDNERMSALAADALRTAGFAVDAVHAAADAEEAVSTTPFDAIILDLGLPDRDGMDLLDTLRRKGVAQPILVLTA
RDGAPSVIAGLNGGADDYMRKPFNVDELIARVRALLRRPGSALGVSLKEGNVELDTIARQARVDGVGLDLSRKEAAALEL
LMRRTGAVISKPALEETLYGYGEEVSSNAVEVLIHRLRKKLAGAGAVVEIHTLRGIGYLLSGARP
>Mature_225_residues
MRILLVEDNERMSALAADALRTAGFAVDAVHAAADAEEAVSTTPFDAIILDLGLPDRDGMDLLDTLRRKGVAQPILVLTA
RDGAPSVIAGLNGGADDYMRKPFNVDELIARVRALLRRPGSALGVSLKEGNVELDTIARQARVDGVGLDLSRKEAAALEL
LMRRTGAVISKPALEETLYGYGEEVSSNAVEVLIHRLRKKLAGAGAVVEIHTLRGIGYLLSGARP

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=46.3636363636364, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=41.8181818181818, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.1559633027523, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=36.3636363636364, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.0807174887892, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=35, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.15859030837, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=32.5991189427313, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=32.618025751073, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=32.8767123287671, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.3304721030043, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.8965517241379, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=29.3103448275862, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=140, Percent_Identity=25, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23928; Mature: 23928

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDNERMSALAADALRTAGFAVDAVHAAADAEEAVSTTPFDAIILDLGLPDRDGM
CEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHCCCCHHHEEEECCCCCCCCH
DLLDTLRRKGVAQPILVLTARDGAPSVIAGLNGGADDYMRKPFNVDELIARVRALLRRPG
HHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHCCC
SALGVSLKEGNVELDTIARQARVDGVGLDLSRKEAAALELLMRRTGAVISKPALEETLYG
HHHEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHC
YGEEVSSNAVEVLIHRLRKKLAGAGAVVEIHTLRGIGYLLSGARP
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MRILLVEDNERMSALAADALRTAGFAVDAVHAAADAEEAVSTTPFDAIILDLGLPDRDGM
CEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHCCCCHHHEEEECCCCCCCCH
DLLDTLRRKGVAQPILVLTARDGAPSVIAGLNGGADDYMRKPFNVDELIARVRALLRRPG
HHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHCCC
SALGVSLKEGNVELDTIARQARVDGVGLDLSRKEAAALELLMRRTGAVISKPALEETLYG
HHHEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHC
YGEEVSSNAVEVLIHRLRKKLAGAGAVVEIHTLRGIGYLLSGARP
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]