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The map label for this gene is oxlT [H]

Identifier: 154245196

GI number: 154245196

Start: 1437682

End: 1438992

Strand: Direct

Name: oxlT [H]

Synonym: Xaut_1248

Alternate gene names: 154245196

Gene position: 1437682-1438992 (Clockwise)

Preceding gene: 154245195

Following gene: 154245214

Centisome position: 27.08

GC content: 66.9

Gene sequence:

>1311_bases
ATGTCGCAGAATCTTTCGACGCCCGTGCGCGGGCCGTTGGGCGGAAGATGGATGCAGCTCGCCATCGGCGTGGTCTGCAT
GTCCATGATCGCCAATCTCCAGTACGGCTGGACGCTGTTCGTCGAACCGATGAACGAGAAACACCAGTGGGGTCGCGCCG
CCATCCAGGTGGCCTTTACCATCTTCGTCGTATTCGAGACGTGGCTGGTCCCGGTGGAAGGCTGGTTCGTGGACAAGTTC
GGACCGCGGCCTGTGGTGTTCATCGGCGGCATCCTGTGCGCCCTGTCCTGGGCTCTCAACTCGGTCGCCGCCAGCCTTCC
CATGCTCTATGTCTCGGCGGCCCTCGGCGGCGCCGGCGCCGGCGCGGTCTATGGTACGGCCGTGGGCGCGGCGCTGAAGT
GGTTCCCGGATCGCCGCGGCCTTGCCGCCGGCATCACCGCCGCCGGCTTCGGCGCCGGATCGGCCCTGACCATCGTGCCC
ATCGCGGCCATGATCAAGGCGCAGGGCTACGAGCACACCTTCCTGTTCTTCGGCCTGATCCAGGGTGCCGTGGTGCTGGT
GGCATCGCTGTTCCTGATGAGCCCGAAGCCCGGCCAGGTGCCGGCCGTCGCCGCCACCTCCACCACCCAGAGCCGTCGCA
GCTATGGTCCGGGCGAGATGCTCAAGGCCCCGGTGTTCTGGGTCATGTATCTGATGTTCGTCCTGGTGGCCGCCGGCGGC
CTGATGGCGACCGCCCAGCTCGGCTCCATCGCCAAGGACTTCAAGATCGCCGACGTGCCGGTCTCGATCCTGGGCCTGAC
CCTGCCGGCCCTGACCTTCGCCTTGTCCATCGACCGGGTGCTGAACGGCGTGACCCGCCCGTTCTTCGGCTGGGTGTCGG
ACAATATCGGGCGTGAGAACACCATGTTCATCGCCTTCTCGCTGGAAGCGGTGGGCGTGCTGGCTCTGGCCAAGTTCGGT
GCCGACCCGATCGCGTTCGTGATCCTCACCGGCCTCGTCTTCTTCGCCTGGGGCGAGATCTACTCGCTGTTCCCGGCGAC
GTGCGGCGATACCTTCGGCTCGCGCTTTGCCACCACCAACGCCGGCCTGCTCTACACCGCGAAGGGCACGGCCTCGCTCG
TGGTGCCGCTGGCTTCGGTCGCGGTTGCCAAGCTCGGCAACTGGGACCTGGTGTTCATGCTGACGGCGGGCGTCAACGCC
CTCGCCGCGCTCATGGCGCTCTTCGTCCTGAAGCCGCTGCGGACCCGGTTCGTGCTCCAAGCGGTAGCGAAGGAAGAGGT
GGACGTCCCCAGCGCCAAGGTCGTCGGCTGA

Upstream 100 bases:

>100_bases
GGTACGCGAGCGGGCTCGGTCAAGAAGGCCCGCATCAAGAATGGTGACCGTCACGGGCCGTTCATCGCTTTCGATGATCC
CCAGTGAGAAAGGGAAGGAA

Downstream 100 bases:

>100_bases
AGATTGCCCGATGGAACGGGGGCGGGGAAACCCGGCCCCGGCATCGGACTTCACCTTGGCCCACCTACCCCGGGCCTAAC
TTGAGGGAGCGGCGTGCCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSQNLSTPVRGPLGGRWMQLAIGVVCMSMIANLQYGWTLFVEPMNEKHQWGRAAIQVAFTIFVVFETWLVPVEGWFVDKF
GPRPVVFIGGILCALSWALNSVAASLPMLYVSAALGGAGAGAVYGTAVGAALKWFPDRRGLAAGITAAGFGAGSALTIVP
IAAMIKAQGYEHTFLFFGLIQGAVVLVASLFLMSPKPGQVPAVAATSTTQSRRSYGPGEMLKAPVFWVMYLMFVLVAAGG
LMATAQLGSIAKDFKIADVPVSILGLTLPALTFALSIDRVLNGVTRPFFGWVSDNIGRENTMFIAFSLEAVGVLALAKFG
ADPIAFVILTGLVFFAWGEIYSLFPATCGDTFGSRFATTNAGLLYTAKGTASLVVPLASVAVAKLGNWDLVFMLTAGVNA
LAALMALFVLKPLRTRFVLQAVAKEEVDVPSAKVVG

Sequences:

>Translated_436_residues
MSQNLSTPVRGPLGGRWMQLAIGVVCMSMIANLQYGWTLFVEPMNEKHQWGRAAIQVAFTIFVVFETWLVPVEGWFVDKF
GPRPVVFIGGILCALSWALNSVAASLPMLYVSAALGGAGAGAVYGTAVGAALKWFPDRRGLAAGITAAGFGAGSALTIVP
IAAMIKAQGYEHTFLFFGLIQGAVVLVASLFLMSPKPGQVPAVAATSTTQSRRSYGPGEMLKAPVFWVMYLMFVLVAAGG
LMATAQLGSIAKDFKIADVPVSILGLTLPALTFALSIDRVLNGVTRPFFGWVSDNIGRENTMFIAFSLEAVGVLALAKFG
ADPIAFVILTGLVFFAWGEIYSLFPATCGDTFGSRFATTNAGLLYTAKGTASLVVPLASVAVAKLGNWDLVFMLTAGVNA
LAALMALFVLKPLRTRFVLQAVAKEEVDVPSAKVVG
>Mature_435_residues
SQNLSTPVRGPLGGRWMQLAIGVVCMSMIANLQYGWTLFVEPMNEKHQWGRAAIQVAFTIFVVFETWLVPVEGWFVDKFG
PRPVVFIGGILCALSWALNSVAASLPMLYVSAALGGAGAGAVYGTAVGAALKWFPDRRGLAAGITAAGFGAGSALTIVPI
AAMIKAQGYEHTFLFFGLIQGAVVLVASLFLMSPKPGQVPAVAATSTTQSRRSYGPGEMLKAPVFWVMYLMFVLVAAGGL
MATAQLGSIAKDFKIADVPVSILGLTLPALTFALSIDRVLNGVTRPFFGWVSDNIGRENTMFIAFSLEAVGVLALAKFGA
DPIAFVILTGLVFFAWGEIYSLFPATCGDTFGSRFATTNAGLLYTAKGTASLVVPLASVAVAKLGNWDLVFMLTAGVNAL
AALMALFVLKPLRTRFVLQAVAKEEVDVPSAKVVG

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=362, Percent_Identity=26.2430939226519, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45981; Mature: 45850

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS ; PS00456 NA_SOLUT_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNLSTPVRGPLGGRWMQLAIGVVCMSMIANLQYGWTLFVEPMNEKHQWGRAAIQVAFT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
IFVVFETWLVPVEGWFVDKFGPRPVVFIGGILCALSWALNSVAASLPMLYVSAALGGAGA
HHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GAVYGTAVGAALKWFPDRRGLAAGITAAGFGAGSALTIVPIAAMIKAQGYEHTFLFFGLI
CHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
QGAVVLVASLFLMSPKPGQVPAVAATSTTQSRRSYGPGEMLKAPVFWVMYLMFVLVAAGG
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
LMATAQLGSIAKDFKIADVPVSILGLTLPALTFALSIDRVLNGVTRPFFGWVSDNIGREN
HHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TMFIAFSLEAVGVLALAKFGADPIAFVILTGLVFFAWGEIYSLFPATCGDTFGSRFATTN
EEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHCCCCEECC
AGLLYTAKGTASLVVPLASVAVAKLGNWDLVFMLTAGVNALAALMALFVLKPLRTRFVLQ
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AVAKEEVDVPSAKVVG
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SQNLSTPVRGPLGGRWMQLAIGVVCMSMIANLQYGWTLFVEPMNEKHQWGRAAIQVAFT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHH
IFVVFETWLVPVEGWFVDKFGPRPVVFIGGILCALSWALNSVAASLPMLYVSAALGGAGA
HHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GAVYGTAVGAALKWFPDRRGLAAGITAAGFGAGSALTIVPIAAMIKAQGYEHTFLFFGLI
CHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
QGAVVLVASLFLMSPKPGQVPAVAATSTTQSRRSYGPGEMLKAPVFWVMYLMFVLVAAGG
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
LMATAQLGSIAKDFKIADVPVSILGLTLPALTFALSIDRVLNGVTRPFFGWVSDNIGREN
HHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TMFIAFSLEAVGVLALAKFGADPIAFVILTGLVFFAWGEIYSLFPATCGDTFGSRFATTN
EEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHCCCCEECC
AGLLYTAKGTASLVVPLASVAVAKLGNWDLVFMLTAGVNALAALMALFVLKPLRTRFVLQ
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AVAKEEVDVPSAKVVG
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]