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The map label for this gene is oxlT [H]

Identifier: 154245195

GI number: 154245195

Start: 1435679

End: 1436974

Strand: Direct

Name: oxlT [H]

Synonym: Xaut_1247

Alternate gene names: 154245195

Gene position: 1435679-1436974 (Clockwise)

Preceding gene: 154245194

Following gene: 154245196

Centisome position: 27.04

GC content: 65.43

Gene sequence:

>1296_bases
ATGGTTGAAGCAGCAGTAAAGGCGCCTGCGACCAATCGCTGGCTGCAACTTGTCGCCGGCATCGTCTGTATGGTCGCCGC
GGCGAACATCCAGTATTCCTGGACGTTGTTTGTCCCGGAAATCGTCTCCACGCACGGCTGGACGCGTGCCTCCGTGCAGG
TCGCCTTCACCGTCTTCGTCGTGGTGCAGACCTGGCTGACGCCCATCGAGGGCTATTTCATCGACAAGTACGGCCCGCGG
GTCATGGTCATGGTGGGCGGCCTGTTCACCGGCCTGTCCTGGGTGCTGAATTCCTATGCCGGCTCGCTCACCGCGCTCTA
TGTGGCGGCGGCTGTCGGCGGCATCGGCGTCGGCTGCGTCTACGCCACCTGCGTGAACGCCGCGCTGAAGTGGTTCCCGG
ATCGCCGCGGCCTGGCCGTGGGCCTCACTGCGGCGGGCTACGGCTCGGGCACGGTGCTGACCATCCTGCCCATCGCCGCG
ATGATCAAGACCAGCGGCTATCAGGACACTTTCTTCACCTTTGGCCTGATCCAGGGCGCGGTGATCCTGCTCGCGGCCGG
CTTCCTGCGGGCGCCGTCCAAGACCGAGGTGATCTATTCCTCCACCGTGGCCCAGAGCCGGCGCGACTATACGCTCGGCG
AGGCGCTCCGGACCCCGGTGTTCTGGATCATGCTCACCCTGTTCGTTCTGACCGTGTCCGGCGGCCTCATGGCCGTGGCG
CAGCTGGGCGTGATCGCCGAAGACCTCGGCGTGAAGCACATCAACGTCGACCTCTACTTCTTCGCCATGGCGGCACTGCC
CTTCGCCCTGATGCTGGACCGCATCCTGAACGGCTTCTCCCGCCCCTTCTTCGGCTGGATCTCCGACCATATCGGCCGTG
AGAAGACCATGTTCTTCGCCTTCGCCATGGAAGGCCTCGGCATCGTCGCGCTGGGCACGTTCGGCCACAATCCGTGGGCG
TTCATCATCCTGTCCGGCGTGGTCTTCCTGGCCTGGGGCGAAGTCTACTCCCTGTTCTCGGCGACTGCCGCGGATACCTT
CGGTTCCAAGCACATCGGCAAGATCTACGGCATGCTCTACACGGCCAAGGGCTTTGCCGCCCTGCTGGTGCCGCTCGCCA
ACATCCTGATGGAGGCGACGGGTACCTGGACCACCGTGCTCTACACGGTGGCCGCCATGGACCTGACCGCGGCCTTCGGA
GCGCTCTTTGTCCTGCGGCCCATGCTGGCGCGCCACCACCGGCAGAATGCAGAGGCGGCCGCTGCTGCGACCGCAGCCCG
CGAAGCGACGGCCTGA

Upstream 100 bases:

>100_bases
AAAAACGCCCGTTTGAACATCCGCCGCTCCATGAGGGACAAAAAGAGGGTGGAGCGGTTAACAACATCAAAAAATATAAA
AGTCTCAAGGGGTAGGAAAA

Downstream 100 bases:

>100_bases
CCCTTCGGATCCGACCGGGTCGGCGCCGCCGGCACGGTCGGTCCTCCAGGTTCAAGTTTCAGAAGATACGAGACATTTTC
CGGTCATCCTGCGGTGCAGG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MVEAAVKAPATNRWLQLVAGIVCMVAAANIQYSWTLFVPEIVSTHGWTRASVQVAFTVFVVVQTWLTPIEGYFIDKYGPR
VMVMVGGLFTGLSWVLNSYAGSLTALYVAAAVGGIGVGCVYATCVNAALKWFPDRRGLAVGLTAAGYGSGTVLTILPIAA
MIKTSGYQDTFFTFGLIQGAVILLAAGFLRAPSKTEVIYSSTVAQSRRDYTLGEALRTPVFWIMLTLFVLTVSGGLMAVA
QLGVIAEDLGVKHINVDLYFFAMAALPFALMLDRILNGFSRPFFGWISDHIGREKTMFFAFAMEGLGIVALGTFGHNPWA
FIILSGVVFLAWGEVYSLFSATAADTFGSKHIGKIYGMLYTAKGFAALLVPLANILMEATGTWTTVLYTVAAMDLTAAFG
ALFVLRPMLARHHRQNAEAAAAATAAREATA

Sequences:

>Translated_431_residues
MVEAAVKAPATNRWLQLVAGIVCMVAAANIQYSWTLFVPEIVSTHGWTRASVQVAFTVFVVVQTWLTPIEGYFIDKYGPR
VMVMVGGLFTGLSWVLNSYAGSLTALYVAAAVGGIGVGCVYATCVNAALKWFPDRRGLAVGLTAAGYGSGTVLTILPIAA
MIKTSGYQDTFFTFGLIQGAVILLAAGFLRAPSKTEVIYSSTVAQSRRDYTLGEALRTPVFWIMLTLFVLTVSGGLMAVA
QLGVIAEDLGVKHINVDLYFFAMAALPFALMLDRILNGFSRPFFGWISDHIGREKTMFFAFAMEGLGIVALGTFGHNPWA
FIILSGVVFLAWGEVYSLFSATAADTFGSKHIGKIYGMLYTAKGFAALLVPLANILMEATGTWTTVLYTVAAMDLTAAFG
ALFVLRPMLARHHRQNAEAAAAATAAREATA
>Mature_431_residues
MVEAAVKAPATNRWLQLVAGIVCMVAAANIQYSWTLFVPEIVSTHGWTRASVQVAFTVFVVVQTWLTPIEGYFIDKYGPR
VMVMVGGLFTGLSWVLNSYAGSLTALYVAAAVGGIGVGCVYATCVNAALKWFPDRRGLAVGLTAAGYGSGTVLTILPIAA
MIKTSGYQDTFFTFGLIQGAVILLAAGFLRAPSKTEVIYSSTVAQSRRDYTLGEALRTPVFWIMLTLFVLTVSGGLMAVA
QLGVIAEDLGVKHINVDLYFFAMAALPFALMLDRILNGFSRPFFGWISDHIGREKTMFFAFAMEGLGIVALGTFGHNPWA
FIILSGVVFLAWGEVYSLFSATAADTFGSKHIGKIYGMLYTAKGFAALLVPLANILMEATGTWTTVLYTVAAMDLTAAFG
ALFVLRPMLARHHRQNAEAAAAATAAREATA

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=357, Percent_Identity=24.9299719887955, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46181; Mature: 46181

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50850 MFS ; PS00456 NA_SOLUT_SYMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEAAVKAPATNRWLQLVAGIVCMVAAANIQYSWTLFVPEIVSTHGWTRASVQVAFTVFV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCHHHHHHHHHHHH
VVQTWLTPIEGYFIDKYGPRVMVMVGGLFTGLSWVLNSYAGSLTALYVAAAVGGIGVGCV
HHHHHHHHHCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YATCVNAALKWFPDRRGLAVGLTAAGYGSGTVLTILPIAAMIKTSGYQDTFFTFGLIQGA
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VILLAAGFLRAPSKTEVIYSSTVAQSRRDYTLGEALRTPVFWIMLTLFVLTVSGGLMAVA
HHHHHHHHHCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLGVIAEDLGVKHINVDLYFFAMAALPFALMLDRILNGFSRPFFGWISDHIGREKTMFFA
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHE
FAMEGLGIVALGTFGHNPWAFIILSGVVFLAWGEVYSLFSATAADTFGSKHIGKIYGMLY
EHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAKGFAALLVPLANILMEATGTWTTVLYTVAAMDLTAAFGALFVLRPMLARHHRQNAEAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AAATAAREATA
HHHHHHHHCCC
>Mature Secondary Structure
MVEAAVKAPATNRWLQLVAGIVCMVAAANIQYSWTLFVPEIVSTHGWTRASVQVAFTVFV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHCCCCCCHHHHHHHHHHHH
VVQTWLTPIEGYFIDKYGPRVMVMVGGLFTGLSWVLNSYAGSLTALYVAAAVGGIGVGCV
HHHHHHHHHCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YATCVNAALKWFPDRRGLAVGLTAAGYGSGTVLTILPIAAMIKTSGYQDTFFTFGLIQGA
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VILLAAGFLRAPSKTEVIYSSTVAQSRRDYTLGEALRTPVFWIMLTLFVLTVSGGLMAVA
HHHHHHHHHCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QLGVIAEDLGVKHINVDLYFFAMAALPFALMLDRILNGFSRPFFGWISDHIGREKTMFFA
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHE
FAMEGLGIVALGTFGHNPWAFIILSGVVFLAWGEVYSLFSATAADTFGSKHIGKIYGMLY
EHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAKGFAALLVPLANILMEATGTWTTVLYTVAAMDLTAAFGALFVLRPMLARHHRQNAEAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AAATAAREATA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]