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The map label for this gene is cdd [H]

Identifier: 154245142

GI number: 154245142

Start: 1373519

End: 1373962

Strand: Reverse

Name: cdd [H]

Synonym: Xaut_1194

Alternate gene names: 154245142

Gene position: 1373962-1373519 (Counterclockwise)

Preceding gene: 154245143

Following gene: 154245141

Centisome position: 25.88

GC content: 66.44

Gene sequence:

>444_bases
ATGGCGACGACCAAGCTCGCACGAAAGCTTCCCGCGCCACGCTCCTACGATCTTGAGGCTCTCTTCGACGCCGCGAAAGC
CGTCTCGAAGAACGCCTATGCGCCCTACTCGCGCTTCCGGGTCGGTGCCGCGCTGCTGTCCGCGAACGGCACGGTGCACG
TGGGCTGCAACGTCGAGAACATCGCCTATCCCATCGGAACCTGCGCCGAGGCTGGCGCGATCGCGGCCGCCCGTGCCGCT
GAAGGGGCAGGCCTCGAAGCCGTCGCCATCGCCATCTATGCGGAGAAGGAAGGCGAAGGTCACGTTGCGTGCACCCCTTG
CGGAGCCTGTCGCCAGCGCATCCTCGAACTGTCGCCTGCCACCACCGTCCACTTCTACGGGTTGGGCGACAAGGTCGTCA
GCGTGACGGCGGCCGACCTGTTGCCCCACGCCTTCACGTTCTGA

Upstream 100 bases:

>100_bases
GCTTCATCCAGGACCAGGCCGCGTCCAAGACCCGCGCCGTATTCGGCGCGGGTTACCTGTGCTAGTGTGCCGTGCAACGT
TCCTCCGATGGAGAGGTGCC

Downstream 100 bases:

>100_bases
GCAAACCACCGGTCACTGGGCGTCTAGTCGAGCAGTAGGCCGAGAATTCGTTGAGCTGGAAGAGGCCGAGACCACCTTCA
TCGCATAGCTCTCAGGGGGC

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MATTKLARKLPAPRSYDLEALFDAAKAVSKNAYAPYSRFRVGAALLSANGTVHVGCNVENIAYPIGTCAEAGAIAAARAA
EGAGLEAVAIAIYAEKEGEGHVACTPCGACRQRILELSPATTVHFYGLGDKVVSVTAADLLPHAFTF

Sequences:

>Translated_147_residues
MATTKLARKLPAPRSYDLEALFDAAKAVSKNAYAPYSRFRVGAALLSANGTVHVGCNVENIAYPIGTCAEAGAIAAARAA
EGAGLEAVAIAIYAEKEGEGHVACTPCGACRQRILELSPATTVHFYGLGDKVVSVTAADLLPHAFTF
>Mature_146_residues
ATTKLARKLPAPRSYDLEALFDAAKAVSKNAYAPYSRFRVGAALLSANGTVHVGCNVENIAYPIGTCAEAGAIAAARAAE
GAGLEAVAIAIYAEKEGEGHVACTPCGACRQRILELSPATTVHFYGLGDKVVSVTAADLLPHAFTF

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=142, Percent_Identity=35.9154929577465, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=34.375, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540514, Length=140, Percent_Identity=37.8571428571429, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=134, Percent_Identity=36.5671641791045, Blast_Score=71, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582741, Length=135, Percent_Identity=37.037037037037, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24582744, Length=145, Percent_Identity=35.1724137931034, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920920, Length=104, Percent_Identity=47.1153846153846, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 15196; Mature: 15065

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTKLARKLPAPRSYDLEALFDAAKAVSKNAYAPYSRFRVGAALLSANGTVHVGCNVEN
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCEEEECCCCHH
IAYPIGTCAEAGAIAAARAAEGAGLEAVAIAIYAEKEGEGHVACTPCGACRQRILELSPA
HCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEECCHHHHHHHHHHCCCC
TTVHFYGLGDKVVSVTAADLLPHAFTF
CEEEEEECCCHHEEHHHHHHCCHHCCC
>Mature Secondary Structure 
ATTKLARKLPAPRSYDLEALFDAAKAVSKNAYAPYSRFRVGAALLSANGTVHVGCNVEN
CCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCEEEECCCCHH
IAYPIGTCAEAGAIAAARAAEGAGLEAVAIAIYAEKEGEGHVACTPCGACRQRILELSPA
HCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEECCHHHHHHHHHHCCCC
TTVHFYGLGDKVVSVTAADLLPHAFTF
CEEEEEECCCHHEEHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]