Click here to switch to the map view.

The map label for this gene is nadA1 [H]

Identifier: 154245131

GI number: 154245131

Start: 1360023

End: 1361066

Strand: Reverse

Name: nadA1 [H]

Synonym: Xaut_1183

Alternate gene names: 154245131

Gene position: 1361066-1360023 (Counterclockwise)

Preceding gene: 154245132

Following gene: 154245130

Centisome position: 25.64

GC content: 67.43

Gene sequence:

>1044_bases
ATGGTCGCACTTGCCCAGCCTGCACTCGCCGAAACCAGCCTCGCCGGGGGCCCCCTTGCGGGAAATGCCCTCTCGGAGGC
CTTCGCCCGCACCACCGCGCTCTATGAGCGGGTCCGGCGGGTGGTGCCGCCCGCCGACTGGGCCTTCTTCGCCGAAGATG
CCGAAGCCATCCTGAGCCTGAAGCGCGAGCGCAACGCGGTGATCCTGGCGCACAATTACCAGACGCCGGAAATCTTCCAC
TGCGTCGCCGACATCGTGGGCGACAGCCTGGCGCTGGCCCGCGAGGCCATGCGGGTGGATGCGGACGTGATCGTGCTCGC
CGGCGTCTATTTCATGGCGGAGACCGCCAAGCTGCTCAACCCCGGCAAGACCGTGCTGATCCCGGACCAGGGCGCCGGCT
GCTCGCTGGCCGATTCCATCACGGCGCAGGACGTGCGCCTCATGCGGCAGGCCTACCCCGGCCTGCCGGTCATCGCCTAT
GTGAACACCTCGGCCGCCGTAAAGGCGGAGGTGGACGTGTGCTGCACCTCGGGCAATGCGGCGCGCATCGTGAAAAGCTT
CGGCGTGCCGAAGGTGATCATGCTGCCCGACCAGTATCTGGCCAAGAACGTGGCGGCCGAGACCGGCATCGAGATCATCT
CCTGGGCCGGCCAGTGCGAGGTGCACGAGCGCTTCACCGCGCAGGACGTGCGCGAGCTGCGCATCGCCAATCCCGGCGTC
ACCGTTCTGGTGCACCCGGAATGCCCGCCGGACGTGGTGGCGGAGGCCGATTTCGCCGGCTCCACCGCCGCCATGAGCGA
TTATGTGGGGCAAAAGCGCCCGCCCCGCGTGGTGCTGCTCACCGAATGCTCCATGAGCGACAACGTCGCCGTGAACTATC
CGGACATCGACTTCGTGCGGCCCTGCAATCTCTGCCCGCACATGAAGAAGATCACCCTTGCCAACATCCGCAAGGCGCTG
GAAGGCAACGTGCACGAAGTGACCATCGCGGCGGACGTGGCGGATCGCGCCCGCGCCTCGGTGGAGCGGATGCTGGCGCT
GTGA

Upstream 100 bases:

>100_bases
CGGGCGCTGGCCGGGACCAAATTGCCCCTCGCGCCCACTTGACAGTGCTTATGCTCAGTATAAGCATATGCCAGACATAT
GCTCAAACTGAGTATAGACA

Downstream 100 bases:

>100_bases
CCGGCTTCGAGCGGCTGGAGGGCCGCCCCGTCATCGTTGGCGGCGGCATCGCCGGGCTTGCCGCCGCCCTGTTCCTCTCG
CCCGAGCCGGTGGTGCTGGT

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVALAQPALAETSLAGGPLAGNALSEAFARTTALYERVRRVVPPADWAFFAEDAEAILSLKRERNAVILAHNYQTPEIFH
CVADIVGDSLALAREAMRVDADVIVLAGVYFMAETAKLLNPGKTVLIPDQGAGCSLADSITAQDVRLMRQAYPGLPVIAY
VNTSAAVKAEVDVCCTSGNAARIVKSFGVPKVIMLPDQYLAKNVAAETGIEIISWAGQCEVHERFTAQDVRELRIANPGV
TVLVHPECPPDVVAEADFAGSTAAMSDYVGQKRPPRVVLLTECSMSDNVAVNYPDIDFVRPCNLCPHMKKITLANIRKAL
EGNVHEVTIAADVADRARASVERMLAL

Sequences:

>Translated_347_residues
MVALAQPALAETSLAGGPLAGNALSEAFARTTALYERVRRVVPPADWAFFAEDAEAILSLKRERNAVILAHNYQTPEIFH
CVADIVGDSLALAREAMRVDADVIVLAGVYFMAETAKLLNPGKTVLIPDQGAGCSLADSITAQDVRLMRQAYPGLPVIAY
VNTSAAVKAEVDVCCTSGNAARIVKSFGVPKVIMLPDQYLAKNVAAETGIEIISWAGQCEVHERFTAQDVRELRIANPGV
TVLVHPECPPDVVAEADFAGSTAAMSDYVGQKRPPRVVLLTECSMSDNVAVNYPDIDFVRPCNLCPHMKKITLANIRKAL
EGNVHEVTIAADVADRARASVERMLAL
>Mature_347_residues
MVALAQPALAETSLAGGPLAGNALSEAFARTTALYERVRRVVPPADWAFFAEDAEAILSLKRERNAVILAHNYQTPEIFH
CVADIVGDSLALAREAMRVDADVIVLAGVYFMAETAKLLNPGKTVLIPDQGAGCSLADSITAQDVRLMRQAYPGLPVIAY
VNTSAAVKAEVDVCCTSGNAARIVKSFGVPKVIMLPDQYLAKNVAAETGIEIISWAGQCEVHERFTAQDVRELRIANPGV
TVLVHPECPPDVVAEADFAGSTAAMSDYVGQKRPPRVVLLTECSMSDNVAVNYPDIDFVRPCNLCPHMKKITLANIRKAL
EGNVHEVTIAADVADRARASVERMLAL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=35.8064516129032, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37222; Mature: 37222

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALAQPALAETSLAGGPLAGNALSEAFARTTALYERVRRVVPPADWAFFAEDAEAILSL
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KRERNAVILAHNYQTPEIFHCVADIVGDSLALAREAMRVDADVIVLAGVYFMAETAKLLN
HHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
PGKTVLIPDQGAGCSLADSITAQDVRLMRQAYPGLPVIAYVNTSAAVKAEVDVCCTSGNA
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEEECCCCH
ARIVKSFGVPKVIMLPDQYLAKNVAAETGIEIISWAGQCEVHERFTAQDVRELRIANPGV
HHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCE
TVLVHPECPPDVVAEADFAGSTAAMSDYVGQKRPPRVVLLTECSMSDNVAVNYPDIDFVR
EEEECCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCC
PCNLCPHMKKITLANIRKALEGNVHEVTIAADVADRARASVERMLAL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVALAQPALAETSLAGGPLAGNALSEAFARTTALYERVRRVVPPADWAFFAEDAEAILSL
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KRERNAVILAHNYQTPEIFHCVADIVGDSLALAREAMRVDADVIVLAGVYFMAETAKLLN
HHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
PGKTVLIPDQGAGCSLADSITAQDVRLMRQAYPGLPVIAYVNTSAAVKAEVDVCCTSGNA
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEEECCCCH
ARIVKSFGVPKVIMLPDQYLAKNVAAETGIEIISWAGQCEVHERFTAQDVRELRIANPGV
HHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCE
TVLVHPECPPDVVAEADFAGSTAAMSDYVGQKRPPRVVLLTECSMSDNVAVNYPDIDFVR
EEEECCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCC
PCNLCPHMKKITLANIRKALEGNVHEVTIAADVADRARASVERMLAL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]