Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 154245101

GI number: 154245101

Start: 1325489

End: 1326901

Strand: Reverse

Name: ubiB [C]

Synonym: Xaut_1153

Alternate gene names: 154245101

Gene position: 1326901-1325489 (Counterclockwise)

Preceding gene: 154245102

Following gene: 154245098

Centisome position: 24.99

GC content: 69.85

Gene sequence:

>1413_bases
GTGCGTAGTAAGCCGGCACGCGCAACACGCCGGGCCCCCATTTCCGAGCCCCCCATGTCCGACAAGATCGCCGACGACGA
ACGCAACCGCTTTTCCGCCCGCGCCGCGCGCTATGCCCGCGTCGGCGCCAATGTGGGGGGCGTCGCGGCGCGCATCGCCG
GCACACGGCTCATGGGCCTCGACCGCAACAGCTCCAACGCCGCCGCCCTCACCGCCGCGCTGGGCGGGCTGAAAGGGCCG
TTGATGAAGGTGGCGCAGCTGATGGCCACCATTCCCGACGCCCTGCCCCCCGAATATGCCGCCGAGCTGCAGAAGCTGCA
GAGCGATGCCCCGCCCATGGGCTGGGCCTTCGTGCGCCGGCGCATGATGGCGGAGCTGGGCCGCGACTGGGAGACACGGT
TCGCGTCCTTCTCCCACCAGCCGGCCGCCGCCGCCTCTCTCGGGCAGGTGCACAGGGCGGTGACGCTGGATGGCGAGGAC
GTGGCCTGCAAGCTCCAGTATCCCGACATGCAGGCGGCGGTGGAGGCGGACCTCTCCCAGCTCGACATCCTGTTCTCCAT
CCAGCGCCGCATGGACGGGGCCATCGACACCCGCGAGATCGCCACCGAAATCGGCGAGCGGGTGCGCGAGGAGCTGGACT
ATCGCCGCGAGGCCCGCCACGCCGCCCTCTACGCCTTCATGCTCGCGGACGAGAGCCGGGTGCGCGTGCCCCGCGTGCGC
GACGACCTCTCCACCGGCCGCCTGTTGACCCTGCAATGGCTGGAGGGCGAGAAGATCCTCGGCTTCACCGACCATCCGCT
GGAGGAACGCAACCAGCTGGCCGAGGCCATGTTCGCCGCCTGGTGGCTGCCGTTCAGCCGGTTCGGGGTGATCCACGGCG
ATCCGCACCTGGGCAATTACACCGTGTTCTCCGAGGCTGGCCGCCCGGCCGGCATCAACCTGCTGGACTACGGCTGCGTG
CGCATCTTCCCGCCGCGCTTCGTGGCCGGGGTGGTGGAGCTTTATCGCGGCCTGATCGCGGGTGACGAGGCCCGCGTGGT
GCATGCCTACGAGACCTGGGGCTTCAAGGGTCTGAAGCGCGAGCTGATCGACGTGCTGAACATCTGGGCGCGCTTCATCT
ACGGCCCGCTCATGGACGACCGGGTGCGTTCCATCGCCGACGGGGTGGCGCCGGGCCAGTACGGCCGCAGGGAAGCTTTC
ACCGTGCACAAGGCCCTGAAGGAGCTGGGGCCGGTGACGGTGCCGCGCGAGTTCGTGTTCATGGACCGCGCCGCCGTGGG
CCTCGGCGCCGTTTTCCTGCACCTCAAGGCGGAACTGAACTTCCACCGCCTGTTCGAGGCCGCCATGGGCGACTTCTCCG
CCGAAGAGGTGGCCACGCGCCAGTCGGACGCGCTGAGGGCGGCGGGGCTTTGA

Upstream 100 bases:

>100_bases
GACGCAGGCGATGACGCCACCGTGTTTCGCGTGGACGCGCTGACGCCGCTTTTGCGCCCCACCCTCCTCGCCCTCACCTC
TCGATCCGACCGGGCCGCCT

Downstream 100 bases:

>100_bases
AGCGTTTTCGAGCGAAGTGGGTACCGGTTCGCGTGAAGAAAACGCAGCACGAAAAAATCTACAGTGCCCGCCCCTCGATC
ACCAGCGCGCCGTCGCGGTC

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRSKPARATRRAPISEPPMSDKIADDERNRFSARAARYARVGANVGGVAARIAGTRLMGLDRNSSNAAALTAALGGLKGP
LMKVAQLMATIPDALPPEYAAELQKLQSDAPPMGWAFVRRRMMAELGRDWETRFASFSHQPAAAASLGQVHRAVTLDGED
VACKLQYPDMQAAVEADLSQLDILFSIQRRMDGAIDTREIATEIGERVREELDYRREARHAALYAFMLADESRVRVPRVR
DDLSTGRLLTLQWLEGEKILGFTDHPLEERNQLAEAMFAAWWLPFSRFGVIHGDPHLGNYTVFSEAGRPAGINLLDYGCV
RIFPPRFVAGVVELYRGLIAGDEARVVHAYETWGFKGLKRELIDVLNIWARFIYGPLMDDRVRSIADGVAPGQYGRREAF
TVHKALKELGPVTVPREFVFMDRAAVGLGAVFLHLKAELNFHRLFEAAMGDFSAEEVATRQSDALRAAGL

Sequences:

>Translated_470_residues
MRSKPARATRRAPISEPPMSDKIADDERNRFSARAARYARVGANVGGVAARIAGTRLMGLDRNSSNAAALTAALGGLKGP
LMKVAQLMATIPDALPPEYAAELQKLQSDAPPMGWAFVRRRMMAELGRDWETRFASFSHQPAAAASLGQVHRAVTLDGED
VACKLQYPDMQAAVEADLSQLDILFSIQRRMDGAIDTREIATEIGERVREELDYRREARHAALYAFMLADESRVRVPRVR
DDLSTGRLLTLQWLEGEKILGFTDHPLEERNQLAEAMFAAWWLPFSRFGVIHGDPHLGNYTVFSEAGRPAGINLLDYGCV
RIFPPRFVAGVVELYRGLIAGDEARVVHAYETWGFKGLKRELIDVLNIWARFIYGPLMDDRVRSIADGVAPGQYGRREAF
TVHKALKELGPVTVPREFVFMDRAAVGLGAVFLHLKAELNFHRLFEAAMGDFSAEEVATRQSDALRAAGL
>Mature_470_residues
MRSKPARATRRAPISEPPMSDKIADDERNRFSARAARYARVGANVGGVAARIAGTRLMGLDRNSSNAAALTAALGGLKGP
LMKVAQLMATIPDALPPEYAAELQKLQSDAPPMGWAFVRRRMMAELGRDWETRFASFSHQPAAAASLGQVHRAVTLDGED
VACKLQYPDMQAAVEADLSQLDILFSIQRRMDGAIDTREIATEIGERVREELDYRREARHAALYAFMLADESRVRVPRVR
DDLSTGRLLTLQWLEGEKILGFTDHPLEERNQLAEAMFAAWWLPFSRFGVIHGDPHLGNYTVFSEAGRPAGINLLDYGCV
RIFPPRFVAGVVELYRGLIAGDEARVVHAYETWGFKGLKRELIDVLNIWARFIYGPLMDDRVRSIADGVAPGQYGRREAF
TVHKALKELGPVTVPREFVFMDRAAVGLGAVFLHLKAELNFHRLFEAAMGDFSAEEVATRQSDALRAAGL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=283, Percent_Identity=30.0353356890459, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI27363457, Length=425, Percent_Identity=24.9411764705882, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI217416386, Length=359, Percent_Identity=25.9052924791086, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41393593, Length=332, Percent_Identity=29.2168674698795, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI217035081, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI34147522, Length=275, Percent_Identity=23.2727272727273, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI2367309, Length=260, Percent_Identity=25.7692307692308, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32565180, Length=348, Percent_Identity=26.4367816091954, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17559152, Length=308, Percent_Identity=26.6233766233766, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=277, Percent_Identity=28.8808664259928, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24662575, Length=308, Percent_Identity=30.8441558441558, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859849, Length=300, Percent_Identity=27.6666666666667, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI22024280, Length=331, Percent_Identity=25.9818731117825, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 52132; Mature: 52132

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSKPARATRRAPISEPPMSDKIADDERNRFSARAARYARVGANVGGVAARIAGTRLMGL
CCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEC
DRNSSNAAALTAALGGLKGPLMKVAQLMATIPDALPPEYAAELQKLQSDAPPMGWAFVRR
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
RMMAELGRDWETRFASFSHQPAAAASLGQVHRAVTLDGEDVACKLQYPDMQAAVEADLSQ
HHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHHH
LDILFSIQRRMDGAIDTREIATEIGERVREELDYRREARHAALYAFMLADESRVRVPRVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DDLSTGRLLTLQWLEGEKILGFTDHPLEERNQLAEAMFAAWWLPFSRFGVIHGDPHLGNY
HCCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
TVFSEAGRPAGINLLDYGCVRIFPPRFVAGVVELYRGLIAGDEARVVHAYETWGFKGLKR
EEEECCCCCCCCCHHHCCHHEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHH
ELIDVLNIWARFIYGPLMDDRVRSIADGVAPGQYGRREAFTVHKALKELGPVTVPREFVF
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
MDRAAVGLGAVFLHLKAELNFHRLFEAAMGDFSAEEVATRQSDALRAAGL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSKPARATRRAPISEPPMSDKIADDERNRFSARAARYARVGANVGGVAARIAGTRLMGL
CCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEC
DRNSSNAAALTAALGGLKGPLMKVAQLMATIPDALPPEYAAELQKLQSDAPPMGWAFVRR
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
RMMAELGRDWETRFASFSHQPAAAASLGQVHRAVTLDGEDVACKLQYPDMQAAVEADLSQ
HHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHHH
LDILFSIQRRMDGAIDTREIATEIGERVREELDYRREARHAALYAFMLADESRVRVPRVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DDLSTGRLLTLQWLEGEKILGFTDHPLEERNQLAEAMFAAWWLPFSRFGVIHGDPHLGNY
HCCCCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
TVFSEAGRPAGINLLDYGCVRIFPPRFVAGVVELYRGLIAGDEARVVHAYETWGFKGLKR
EEEECCCCCCCCCHHHCCHHEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHH
ELIDVLNIWARFIYGPLMDDRVRSIADGVAPGQYGRREAFTVHKALKELGPVTVPREFVF
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
MDRAAVGLGAVFLHLKAELNFHRLFEAAMGDFSAEEVATRQSDALRAAGL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]