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The map label for this gene is uidR [H]

Identifier: 154245098

GI number: 154245098

Start: 1323227

End: 1323895

Strand: Reverse

Name: uidR [H]

Synonym: Xaut_1150

Alternate gene names: 154245098

Gene position: 1323895-1323227 (Counterclockwise)

Preceding gene: 154245101

Following gene: 154245097

Centisome position: 24.94

GC content: 70.85

Gene sequence:

>669_bases
ATGACCTCTTCCACGGCGCCCGCCCCGGCCGCATCGCTGCCAAACGCCAAGCCCGCGAGCCGGGCCGACCACCGCTCGGA
GCAGCGCCAGCGCATCCTCGGTGCCGCCGTGGCCTGCTTCTCCCGCGACGGGTTCCACGGCGCCTCCATGCAGAAGATCT
GCGCCGAGGCGGGCATGAGCCCGGGCGCGCTCTATCGCTATTTCCCCTCCAAGGAATCCCTCATCGCCGCCATTGCGGAG
GGGGAACGGTCGGAGCGGCTCGCCTTCTTTGACGCCGTCTCCAAGGCGCCGTCCGTGCTCGACGCCCTGACCGACTGCAC
CGCCGCGATGATGGAGGAAGGCTGCCTCGCCACGGCCCGTCTCGGCCCCGAGGTCATGGCAGAGGCCATCCGCAACGCGG
ACCTGCGCGCCGCCGTGGAGCCCCACGAGGAGGAGAGCCGCGTCCAGCTGAAGGCGGCCCTCGCCAATGCGGTGGCCCAG
GGCGAGGTCGACCCGGCGCTGGATCTCGACACGGTGGTTCTGCTGCTCCAGATCATCGGCGATGGGGTGCTGCTCCACCA
TCAGCTGCATCCCCAGTGGCGGCTTGCCGAGCGGCTGCCGGCGTTCGCACAGCTGGTCAAGCGCATGCTCGCGCCCGATG
CCCCGGTGCCGGCGGAGGCTAAAGCGTGA

Upstream 100 bases:

>100_bases
ACGAACGTTCACTCTTGCTCGCCGCAGTGCAGCGTGATAATGCGAACGAACATTCGCTCTCATTGCTTCCGGCGCGCGTT
TGCCGGATGGACCCCTGCCC

Downstream 100 bases:

>100_bases
CCGCAATGCCACAGCCCCTCGCAAGCGGTGCCGCAGCCGCCTTCCGTCACGTTAATGCCGTGGTCTCGCCCCACGGTCCC
GCCCCGATCCGGAAAGAGGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTSSTAPAPAASLPNAKPASRADHRSEQRQRILGAAVACFSRDGFHGASMQKICAEAGMSPGALYRYFPSKESLIAAIAE
GERSERLAFFDAVSKAPSVLDALTDCTAAMMEEGCLATARLGPEVMAEAIRNADLRAAVEPHEEESRVQLKAALANAVAQ
GEVDPALDLDTVVLLLQIIGDGVLLHHQLHPQWRLAERLPAFAQLVKRMLAPDAPVPAEAKA

Sequences:

>Translated_222_residues
MTSSTAPAPAASLPNAKPASRADHRSEQRQRILGAAVACFSRDGFHGASMQKICAEAGMSPGALYRYFPSKESLIAAIAE
GERSERLAFFDAVSKAPSVLDALTDCTAAMMEEGCLATARLGPEVMAEAIRNADLRAAVEPHEEESRVQLKAALANAVAQ
GEVDPALDLDTVVLLLQIIGDGVLLHHQLHPQWRLAERLPAFAQLVKRMLAPDAPVPAEAKA
>Mature_221_residues
TSSTAPAPAASLPNAKPASRADHRSEQRQRILGAAVACFSRDGFHGASMQKICAEAGMSPGALYRYFPSKESLIAAIAEG
ERSERLAFFDAVSKAPSVLDALTDCTAAMMEEGCLATARLGPEVMAEAIRNADLRAAVEPHEEESRVQLKAALANAVAQG
EVDPALDLDTVVLLLQIIGDGVLLHHQLHPQWRLAERLPAFAQLVKRMLAPDAPVPAEAKA

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=156, Percent_Identity=32.6923076923077, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23598; Mature: 23467

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSTAPAPAASLPNAKPASRADHRSEQRQRILGAAVACFSRDGFHGASMQKICAEAGMS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
PGALYRYFPSKESLIAAIAEGERSERLAFFDAVSKAPSVLDALTDCTAAMMEEGCLATAR
CCHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGPEVMAEAIRNADLRAAVEPHEEESRVQLKAALANAVAQGEVDPALDLDTVVLLLQIIG
CCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
DGVLLHHQLHPQWRLAERLPAFAQLVKRMLAPDAPVPAEAKA
CCCEEECCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TSSTAPAPAASLPNAKPASRADHRSEQRQRILGAAVACFSRDGFHGASMQKICAEAGMS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
PGALYRYFPSKESLIAAIAEGERSERLAFFDAVSKAPSVLDALTDCTAAMMEEGCLATAR
CCHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGPEVMAEAIRNADLRAAVEPHEEESRVQLKAALANAVAQGEVDPALDLDTVVLLLQIIG
CCHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
DGVLLHHQLHPQWRLAERLPAFAQLVKRMLAPDAPVPAEAKA
CCCEEECCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]