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The map label for this gene is qseC [H]

Identifier: 154245025

GI number: 154245025

Start: 1234897

End: 1236231

Strand: Direct

Name: qseC [H]

Synonym: Xaut_1076

Alternate gene names: 154245025

Gene position: 1234897-1236231 (Clockwise)

Preceding gene: 154245024

Following gene: 154245036

Centisome position: 23.26

GC content: 72.81

Gene sequence:

>1335_bases
ATGAGCTCGCTCAAGCGCAGGCTGGTGCTGATCCTGCTGGCGGCCACGGGGGTCATCTGGCTGTGCGCCACCGGCTGGAT
CTACGCCTCCAGCCGCAGCGAGCTGGAGCATGTTCTGGATACCCGCCTGCAGGAGGCGGCGCGCATGGTCCACTCGCTGG
TGGCCGGCGGCAACATCGCCGCCGCCGCGGCCGTGGCACAGGTGGCGAATCCGCCGGAGTCCGGCTACGAGCGCCAGCTC
TCGTGCCAGATCTGGTCACTGGACGGGCGCCTCGTCGCGAAATCGGGCGGCGCGCCGGAGGAGGCGCTGGCAGGTCCTGC
GGAAGGCTTCTCCGAACGCATGGTCAATGGCGAGCCGTGGCGGGTCTACACCATCCTCGATCCGGACAAGGGCGTGCGGG
TGATGGTGGGCGACCGCATCGGCCTGCGCGACCGGCTGGTGCGTGATCTGGTGGCGGGGCTGCTCGCGCCGATGATCCTC
GTCGTGCCCCTGCTCGGCCTGCTCATCTGGATCAGCGTCGGCCGTGGCCTCAAGCCGCTCCATGTCGTGGCCGGCGACAT
CGCCGCCCGCGACGGCGAAGACATGCGCCCCGTGGCGCCCGCCGCCGCCCCGGCCGAGATCCGCCCGCTGCTGGAGGCCA
TCAACGGTCTGTTCGCCAAGGTGGAGGCCGCGCGGCGGCAGGAGCGCGACGTGACCGCCTTCGCCGCGCACGAACTGCGC
ACACCCCTCGCCGGCCTGAAGACGCAGGCCCAGATCGCGCTCGCCGCGCACGACGCGCCGACGCGGGAGGGTGCGCTCAG
GCAGATCCTCGTCTCCGTGGACCGCACCACCCGCCTCGTGCGGCAGCTGCTGGCGCTCGCCAAGCTCGAAGGCACGCCGT
CTCCGCCGCTCGAAGCCGTGGGCGAGGCCGAGGCCGGGGCGCTGCTGCGTGAGATCGTGCGCCAGACGGCGAAGCCCGGG
TCGGCGCATGTGGAGGTGGACGACGCCCTCGACGCGGTGAAGCTGAAGGGCGACCACGAGGCGCTGCACCTGATGCTGCG
GAACCTGCACGAGAACGCCGTCGAGCATATGGCCGGCGGCGGCACCATCGCGTGGCGTCAATGCGCCGGCGGGCTGTGCG
TGGAGGACGAGGGGCCGGGCATTCCCGAGGACGAGCTGCCGCTGGTGACGCGTCGTTTCTACCGGGGCCGCAGCCGGAGC
GGAGCGGGGAGCGGCCTCGGCCTCACCATCGCCACCATGGCCGCTGCCCGGGCCGGCGCCCGGCTCACGCTGGAGAACCG
CCGCGATCGCGATGGCCTGAGGGCGAGCGTCGTGTGGCCGCGCGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCAACGCGGTGGAGGTGCACATCCACAATCTTCGGGCCAAGGTCGGCCGCGAGACCATCGAGACCGTGCGCGGCCTCGGC
TATCGCGTCAGGGGGCCGGC

Downstream 100 bases:

>100_bases
TGTAGCGTTTCAGGCCTTGTCGTGAAAGCCGACGCGGCCCGGCAACGCTTGTGCCCGGCCGCATCAGGCTGAAGGCCGCG
ACCTGTCTGGTGCTCAGCCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSSLKRRLVLILLAATGVIWLCATGWIYASSRSELEHVLDTRLQEAARMVHSLVAGGNIAAAAAVAQVANPPESGYERQL
SCQIWSLDGRLVAKSGGAPEEALAGPAEGFSERMVNGEPWRVYTILDPDKGVRVMVGDRIGLRDRLVRDLVAGLLAPMIL
VVPLLGLLIWISVGRGLKPLHVVAGDIAARDGEDMRPVAPAAAPAEIRPLLEAINGLFAKVEAARRQERDVTAFAAHELR
TPLAGLKTQAQIALAAHDAPTREGALRQILVSVDRTTRLVRQLLALAKLEGTPSPPLEAVGEAEAGALLREIVRQTAKPG
SAHVEVDDALDAVKLKGDHEALHLMLRNLHENAVEHMAGGGTIAWRQCAGGLCVEDEGPGIPEDELPLVTRRFYRGRSRS
GAGSGLGLTIATMAAARAGARLTLENRRDRDGLRASVVWPRGAA

Sequences:

>Translated_444_residues
MSSLKRRLVLILLAATGVIWLCATGWIYASSRSELEHVLDTRLQEAARMVHSLVAGGNIAAAAAVAQVANPPESGYERQL
SCQIWSLDGRLVAKSGGAPEEALAGPAEGFSERMVNGEPWRVYTILDPDKGVRVMVGDRIGLRDRLVRDLVAGLLAPMIL
VVPLLGLLIWISVGRGLKPLHVVAGDIAARDGEDMRPVAPAAAPAEIRPLLEAINGLFAKVEAARRQERDVTAFAAHELR
TPLAGLKTQAQIALAAHDAPTREGALRQILVSVDRTTRLVRQLLALAKLEGTPSPPLEAVGEAEAGALLREIVRQTAKPG
SAHVEVDDALDAVKLKGDHEALHLMLRNLHENAVEHMAGGGTIAWRQCAGGLCVEDEGPGIPEDELPLVTRRFYRGRSRS
GAGSGLGLTIATMAAARAGARLTLENRRDRDGLRASVVWPRGAA
>Mature_443_residues
SSLKRRLVLILLAATGVIWLCATGWIYASSRSELEHVLDTRLQEAARMVHSLVAGGNIAAAAAVAQVANPPESGYERQLS
CQIWSLDGRLVAKSGGAPEEALAGPAEGFSERMVNGEPWRVYTILDPDKGVRVMVGDRIGLRDRLVRDLVAGLLAPMILV
VPLLGLLIWISVGRGLKPLHVVAGDIAARDGEDMRPVAPAAAPAEIRPLLEAINGLFAKVEAARRQERDVTAFAAHELRT
PLAGLKTQAQIALAAHDAPTREGALRQILVSVDRTTRLVRQLLALAKLEGTPSPPLEAVGEAEAGALLREIVRQTAKPGS
AHVEVDDALDAVKLKGDHEALHLMLRNLHENAVEHMAGGGTIAWRQCAGGLCVEDEGPGIPEDELPLVTRRFYRGRSRSG
AGSGLGLTIATMAAARAGARLTLENRRDRDGLRASVVWPRGAA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=446, Percent_Identity=32.9596412556054, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1790551, Length=318, Percent_Identity=29.874213836478, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=34.3220338983051, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786783, Length=339, Percent_Identity=26.5486725663717, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=28.3950617283951, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=271, Percent_Identity=28.7822878228782, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47329; Mature: 47198

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLKRRLVLILLAATGVIWLCATGWIYASSRSELEHVLDTRLQEAARMVHSLVAGGNIA
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AAAAVAQVANPPESGYERQLSCQIWSLDGRLVAKSGGAPEEALAGPAEGFSERMVNGEPW
HHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEECCCCCCHHHHCCCCCCHHHHCCCCCCE
RVYTILDPDKGVRVMVGDRIGLRDRLVRDLVAGLLAPMILVVPLLGLLIWISVGRGLKPL
EEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HVVAGDIAARDGEDMRPVAPAAAPAEIRPLLEAINGLFAKVEAARRQERDVTAFAAHELR
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TPLAGLKTQAQIALAAHDAPTREGALRQILVSVDRTTRLVRQLLALAKLEGTPSPPLEAV
CCHHCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GEAEAGALLREIVRQTAKPGSAHVEVDDALDAVKLKGDHEALHLMLRNLHENAVEHMAGG
CCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GTIAWRQCAGGLCVEDEGPGIPEDELPLVTRRFYRGRSRSGAGSGLGLTIATMAAARAGA
CCEEHHHHCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
RLTLENRRDRDGLRASVVWPRGAA
EEEECCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SSLKRRLVLILLAATGVIWLCATGWIYASSRSELEHVLDTRLQEAARMVHSLVAGGNIA
CHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AAAAVAQVANPPESGYERQLSCQIWSLDGRLVAKSGGAPEEALAGPAEGFSERMVNGEPW
HHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEECCCCCCHHHHCCCCCCHHHHCCCCCCE
RVYTILDPDKGVRVMVGDRIGLRDRLVRDLVAGLLAPMILVVPLLGLLIWISVGRGLKPL
EEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HVVAGDIAARDGEDMRPVAPAAAPAEIRPLLEAINGLFAKVEAARRQERDVTAFAAHELR
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TPLAGLKTQAQIALAAHDAPTREGALRQILVSVDRTTRLVRQLLALAKLEGTPSPPLEAV
CCHHCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
GEAEAGALLREIVRQTAKPGSAHVEVDDALDAVKLKGDHEALHLMLRNLHENAVEHMAGG
CCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
GTIAWRQCAGGLCVEDEGPGIPEDELPLVTRRFYRGRSRSGAGSGLGLTIATMAAARAGA
CCEEHHHHCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
RLTLENRRDRDGLRASVVWPRGAA
EEEECCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]