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The map label for this gene is eda [H]

Identifier: 154244969

GI number: 154244969

Start: 1170831

End: 1171472

Strand: Direct

Name: eda [H]

Synonym: Xaut_1019

Alternate gene names: 154244969

Gene position: 1170831-1171472 (Clockwise)

Preceding gene: 154244968

Following gene: 154244979

Centisome position: 22.05

GC content: 74.45

Gene sequence:

>642_bases
GTGACCGATCAGATCCAGCCCGGGCTTCACTCCATTCTCTCCCGCGCCCCGGTGGTGCCCGTGGTGGTGGTGGAGCGCGC
CGCCGATGCCGTTCCGCTGGCCCGCGCTTTGGTGGCGGGCGGCCTGCCAGCCATCGAGATCACCCTGCGTACGCCGGCTG
CCCTCGACGCCATCCGCGCCGTGGCGCAGGAGGTGGAGGGCGCCATTCCCGGCGTCGGCACGGTGCTCGACGCCGCCCAG
CTGGAGGCTGCCGAGAAGGCCGGCGCGCGTTTTGCCGTCTCGCCCGGCGCCACGCCGCGCCTGCTGGACGCCGCCGCCTC
CTTCGCCATCCCGCTGTTGCCCGGCATCGCCACGGCCGGGGAGGCCATGGGCCTGATCGAGCGCGGCTACCGCTTCGCCA
AGTTCTTCCCGGCGGAGCCGGCGGGCGGCAGCGCCTATCTCGCCTCCATCGCCTCGCCGTTGCCGCAGCTCACCTTCTGC
CCCACCGGCGGCATCAGCCTCGCCTCCGCGCCGCGCTATCTGGCCCTGCCCAACGTGATCTGCGTCGGCGGCTCCTGGAT
GCTGCCGCGCGCGCAGGTGGACGCCGGCGACTGGGCGGCCATCGAGGCCGCGAGCCGGGCGGCGGCAGCGCTCAAGTCCT
GA

Upstream 100 bases:

>100_bases
GCGCTTCCCACTCCGGCGTCGGCCGCGAGCTCTTCGCCCCCTTCCGAAACGCCGTCGGCCAGGCCGAAAAGGGCGCAAGC
ATTTTCCAGGAGGTTTTCGC

Downstream 100 bases:

>100_bases
GGACGGACACCCGGGGGTGAGGGCGAGATCCCCTCGCCCCCGCGCCGCGCGGTCTCAAAGCGTCGAGAAGCGGTAGATGG
AGACGTGCCGGTAGGTCGCG

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDQIQPGLHSILSRAPVVPVVVVERAADAVPLARALVAGGLPAIEITLRTPAALDAIRAVAQEVEGAIPGVGTVLDAAQ
LEAAEKAGARFAVSPGATPRLLDAAASFAIPLLPGIATAGEAMGLIERGYRFAKFFPAEPAGGSAYLASIASPLPQLTFC
PTGGISLASAPRYLALPNVICVGGSWMLPRAQVDAGDWAAIEAASRAAAALKS

Sequences:

>Translated_213_residues
MTDQIQPGLHSILSRAPVVPVVVVERAADAVPLARALVAGGLPAIEITLRTPAALDAIRAVAQEVEGAIPGVGTVLDAAQ
LEAAEKAGARFAVSPGATPRLLDAAASFAIPLLPGIATAGEAMGLIERGYRFAKFFPAEPAGGSAYLASIASPLPQLTFC
PTGGISLASAPRYLALPNVICVGGSWMLPRAQVDAGDWAAIEAASRAAAALKS
>Mature_212_residues
TDQIQPGLHSILSRAPVVPVVVVERAADAVPLARALVAGGLPAIEITLRTPAALDAIRAVAQEVEGAIPGVGTVLDAAQL
EAAEKAGARFAVSPGATPRLLDAAASFAIPLLPGIATAGEAMGLIERGYRFAKFFPAEPAGGSAYLASIASPLPQLTFCP
TGGISLASAPRYLALPNVICVGGSWMLPRAQVDAGDWAAIEAASRAAAALKS

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=199, Percent_Identity=52.7638190954774, Blast_Score=178, Evalue=3e-46,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 21480; Mature: 21349

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQIQPGLHSILSRAPVVPVVVVERAADAVPLARALVAGGLPAIEITLRTPAALDAIRA
CCCCCCHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
VAQEVEGAIPGVGTVLDAAQLEAAEKAGARFAVSPGATPRLLDAAASFAIPLLPGIATAG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
EAMGLIERGYRFAKFFPAEPAGGSAYLASIASPLPQLTFCPTGGISLASAPRYLALPNVI
HHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEECCCEE
CVGGSWMLPRAQVDAGDWAAIEAASRAAAALKS
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQIQPGLHSILSRAPVVPVVVVERAADAVPLARALVAGGLPAIEITLRTPAALDAIRA
CCCCCHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
VAQEVEGAIPGVGTVLDAAQLEAAEKAGARFAVSPGATPRLLDAAASFAIPLLPGIATAG
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
EAMGLIERGYRFAKFFPAEPAGGSAYLASIASPLPQLTFCPTGGISLASAPRYLALPNVI
HHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEECCCEE
CVGGSWMLPRAQVDAGDWAAIEAASRAAAALKS
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]