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The map label for this gene is dhmA [H]

Identifier: 154244905

GI number: 154244905

Start: 1074017

End: 1074946

Strand: Direct

Name: dhmA [H]

Synonym: Xaut_0955

Alternate gene names: 154244905

Gene position: 1074017-1074946 (Clockwise)

Preceding gene: 154244901

Following gene: 154244906

Centisome position: 20.23

GC content: 69.14

Gene sequence:

>930_bases
ATGCTGAATGCGTTTCTCCAGGCCGTCCGTCCGGCTGCGGCCGGCTCCACTCCGGTGGCCACGGTGGCTTATCGCCGGGC
GGCGGTCGGCGGCCTCGACATTTTCTATCGGGATGCGGGACCGGCCGACGCGCCGGTGATCGTGCTGCTGCACGGCTTTC
CCTCCTCCTCCCACATGTTCCGGAATCTCATTCCCGCGCTGGCCGACCGCTACCGCGTGATCGCGCCGGACTATCCGGGC
TTCGGCTATTCCAGCGCCCCGGCGCCCGAGGATTTCGCCTACAGCTTCGATGCCCTCGCCGACGTGGTGGAGACGTTGCT
CGCAGACCTCGGCGTGCGCCGCTACGCGCTCTACTTGCAGGATTTCGGTGGACCCGTGGGCATGCGCATCGCCGCCCGTC
ATCCGGAGCGGGTCACTGGCCTCATCGTGCAGAATTCGGTGGCGAACCTGGAAGGCTTCGCCGCCAGCGCGGTGGGCACC
TTCGGACCCTACTGGGCCGACCGCAATGCCGAGACGGAAAAGCCCCTCCGCGGCTTCCTCACCGCCGAGACCACGCGCTT
CCAGTATGAGCACGGCGCCTCGGCCCGCGCGGATCGCGTCAGCCCGGATGCCTGGCAGCACGACCAGTGGCTACTGGACC
GCCCCGGCAACGACCGGATCCAGCTGGAGCTGCTCTACCGCTACCAGGACAATGTGGGCGCCTATCCGCAGTGGCAGGCC
TATCTGCGCGCGCACCAGCCGAACATCCTGGTGACCTGGGGCGACAACGACCCCTTCTTCACCGCCGCCGGCCGCGACCT
GTTCAAGGCGCTGGTGCCGGCCACCGAGGTGCACGCCTACGACGCCGGCCATTTCGCTCTGGAGACCCACGGGCCGGAGA
TCGCCGCCGCCATCCGCGCCTTCCTCGCCCGCGTGGCTCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
AGGCCGGGGCGGAAGGGTGAAACCGTTAAAAATAATTTGACAGGTTACATCGGGTATGTAACTCCATTCGTGGCATTAAG
CCAGTTACGAAAGGTGCCCC

Downstream 100 bases:

>100_bases
CGCCGGTCGCGCGCGCCCTCGCGCATCACCGGTCGCCGCGCCGGCCGATCCCGGCGTGGCGACCTTGCTGCCCCTTGCGG
AGTTTTCCGATGCCTTCCCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MLNAFLQAVRPAAAGSTPVATVAYRRAAVGGLDIFYRDAGPADAPVIVLLHGFPSSSHMFRNLIPALADRYRVIAPDYPG
FGYSSAPAPEDFAYSFDALADVVETLLADLGVRRYALYLQDFGGPVGMRIAARHPERVTGLIVQNSVANLEGFAASAVGT
FGPYWADRNAETEKPLRGFLTAETTRFQYEHGASARADRVSPDAWQHDQWLLDRPGNDRIQLELLYRYQDNVGAYPQWQA
YLRAHQPNILVTWGDNDPFFTAAGRDLFKALVPATEVHAYDAGHFALETHGPEIAAAIRAFLARVAPAA

Sequences:

>Translated_309_residues
MLNAFLQAVRPAAAGSTPVATVAYRRAAVGGLDIFYRDAGPADAPVIVLLHGFPSSSHMFRNLIPALADRYRVIAPDYPG
FGYSSAPAPEDFAYSFDALADVVETLLADLGVRRYALYLQDFGGPVGMRIAARHPERVTGLIVQNSVANLEGFAASAVGT
FGPYWADRNAETEKPLRGFLTAETTRFQYEHGASARADRVSPDAWQHDQWLLDRPGNDRIQLELLYRYQDNVGAYPQWQA
YLRAHQPNILVTWGDNDPFFTAAGRDLFKALVPATEVHAYDAGHFALETHGPEIAAAIRAFLARVAPAA
>Mature_309_residues
MLNAFLQAVRPAAAGSTPVATVAYRRAAVGGLDIFYRDAGPADAPVIVLLHGFPSSSHMFRNLIPALADRYRVIAPDYPG
FGYSSAPAPEDFAYSFDALADVVETLLADLGVRRYALYLQDFGGPVGMRIAARHPERVTGLIVQNSVANLEGFAASAVGT
FGPYWADRNAETEKPLRGFLTAETTRFQYEHGASARADRVSPDAWQHDQWLLDRPGNDRIQLELLYRYQDNVGAYPQWQA
YLRAHQPNILVTWGDNDPFFTAAGRDLFKALVPATEVHAYDAGHFALETHGPEIAAAIRAFLARVAPAA

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=135, Percent_Identity=34.0740740740741, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI29294637, Length=127, Percent_Identity=38.5826771653543, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI29294635, Length=127, Percent_Identity=38.5826771653543, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI29294639, Length=127, Percent_Identity=38.5826771653543, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI27597073, Length=144, Percent_Identity=34.7222222222222, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324392, Length=276, Percent_Identity=40.2173913043478, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33804; Mature: 33804

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAFLQAVRPAAAGSTPVATVAYRRAAVGGLDIFYRDAGPADAPVIVLLHGFPSSSHMF
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCHHHHH
RNLIPALADRYRVIAPDYPGFGYSSAPAPEDFAYSFDALADVVETLLADLGVRRYALYLQ
HHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DFGGPVGMRIAARHPERVTGLIVQNSVANLEGFAASAVGTFGPYWADRNAETEKPLRGFL
HCCCCCCEEEECCCCCHHEEEEEECCHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
TAETTRFQYEHGASARADRVSPDAWQHDQWLLDRPGNDRIQLELLYRYQDNVGAYPQWQA
HHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHH
YLRAHQPNILVTWGDNDPFFTAAGRDLFKALVPATEVHAYDAGHFALETHGPEIAAAIRA
HHHHCCCCEEEEECCCCCEEECCHHHHHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHH
FLARVAPAA
HHHHHCCCC
>Mature Secondary Structure
MLNAFLQAVRPAAAGSTPVATVAYRRAAVGGLDIFYRDAGPADAPVIVLLHGFPSSSHMF
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEECCCCHHHHH
RNLIPALADRYRVIAPDYPGFGYSSAPAPEDFAYSFDALADVVETLLADLGVRRYALYLQ
HHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DFGGPVGMRIAARHPERVTGLIVQNSVANLEGFAASAVGTFGPYWADRNAETEKPLRGFL
HCCCCCCEEEECCCCCHHEEEEEECCHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
TAETTRFQYEHGASARADRVSPDAWQHDQWLLDRPGNDRIQLELLYRYQDNVGAYPQWQA
HHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCHHHHH
YLRAHQPNILVTWGDNDPFFTAAGRDLFKALVPATEVHAYDAGHFALETHGPEIAAAIRA
HHHHCCCCEEEEECCCCCEEECCHHHHHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHH
FLARVAPAA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA