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The map label for this gene is mhpT [H]

Identifier: 154244889

GI number: 154244889

Start: 1058763

End: 1060016

Strand: Direct

Name: mhpT [H]

Synonym: Xaut_0939

Alternate gene names: 154244889

Gene position: 1058763-1060016 (Clockwise)

Preceding gene: 154244888

Following gene: 154244890

Centisome position: 19.94

GC content: 68.34

Gene sequence:

>1254_bases
ATGCATGAACGCTGGCCGCAACGGGTCGCACCAGACGGGAGGAAAATGAACATGACGATTGCTTTGAAATCGGCCTCTGC
GGGAAGCAGGGCGCTTGTCTACGTCTCGCTTGCCGCCGTGATCGAAGGCTTCGACCTGCAGGCGGCCGGCATCGCCGCCC
CCAAGATCGGGCCGGCGTTCCACATGACGCCCCAGCAGATGGGGCTGTTCTTTTCCGCCGCTACCTTCGGGCTGATGTTC
GGCGCGCTCGTGGGCGGCTATACGGCCGATCGCTGGGGGAGGCGCGCCGGGCTCGTCATTGCTTTGGCGGCCTTCGGTGT
CGCCTCCATCGCCACCATCTTCTCGACTTCGGTGGAGATGCTGATCGCGCTGCGTTTCCTCACCGGCGTCGGGCTCGGCG
GCGCGTTGCCGAACCTCGTGTCCATCGCTTCGGAAGCCGTCGGCCCGGAGCGCAAGGGGCGCGCGGTGGCCATCATGTAT
GCCGGGATGCCGTTGGGGGCCGCGGTGGCGAGCCTTGTCGCCCTGCTCGATCTGCATGGCGGCGACTGGCGTTCCATCTT
CCTGGTGGGTGGCATCCTGCCGCTGCTCCTTGTCCCCTTCATCTATGCCGGCCTGCCGCCGTTGAAGACGGTGGCGAGCA
CCTCGGAGCGGAAGACGCCGTGGACCGAGGTGTTCCGTCCCGACGCCATGGTCACCACGGTGCTGTTGTGGAGTGCCTTC
TTCCTCGGCCTGATGGTGGTCTATCTGCTTATGAACTGGCTGCCGCAGCTCCTGGTGGGGCAGGGCTTCTCGCGTAGCGA
GGCCTCGCTGGCGCTGATCCTCTACAGCCTCGGCGGCACCGTGGGCAGCCTCATCGGCGGGCGGGTCCTCGACGGCAGCC
AGCGCGTCGTGGCCATCGGCGCCAGCTTCGCCTTCGTGGCCGCCGCCCTTGCGATGCTGGGCCTGCTTCCGCCAGCGCTC
GCGACCATGCTCGTCACCGTGACCCTGGTGGGCGTGGGCGTGCTGTGCGTGCAGTCGATCCTCTACGGCATCGCCCCGCA
ATGCTACCCATCGGAGATCCGGGGCACCGGTGTGGGCGTCGTGGTCGCCGTCGGGCGTCTCGGCTCCATGGCCGGTCCGC
TGCTGGCGGGTGTGCTGGTGGCGCAGGGCAGCACACCGGCGGACGTGATGCTGGTCCTGGTGCCCATCATCCTGGCGTGC
GGGCTGGGCACCCTCGCCCTGGTGGCCCGGCGGTTTCGCCCCGCCCTTGCCTGA

Upstream 100 bases:

>100_bases
GCCTGACAACCGCATCGCAAGTCCGGCAGGGCGCTCCCCGTTCGGGATGCGCCCTGCCGTGCCCGCGACACAACCTGAAA
CCGCCGGGGATCATCGGCGG

Downstream 100 bases:

>100_bases
TCCACGCCTCGCCCCCCGGCGCTGCCGGGGGGCCGCAAGCGCGGGCGGGATGATCGAAACCTCCAGGGAAGGAACATGAA
ATGAAGCTCTTGCGATTTGG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MHERWPQRVAPDGRKMNMTIALKSASAGSRALVYVSLAAVIEGFDLQAAGIAAPKIGPAFHMTPQQMGLFFSAATFGLMF
GALVGGYTADRWGRRAGLVIALAAFGVASIATIFSTSVEMLIALRFLTGVGLGGALPNLVSIASEAVGPERKGRAVAIMY
AGMPLGAAVASLVALLDLHGGDWRSIFLVGGILPLLLVPFIYAGLPPLKTVASTSERKTPWTEVFRPDAMVTTVLLWSAF
FLGLMVVYLLMNWLPQLLVGQGFSRSEASLALILYSLGGTVGSLIGGRVLDGSQRVVAIGASFAFVAAALAMLGLLPPAL
ATMLVTVTLVGVGVLCVQSILYGIAPQCYPSEIRGTGVGVVVAVGRLGSMAGPLLAGVLVAQGSTPADVMLVLVPIILAC
GLGTLALVARRFRPALA

Sequences:

>Translated_417_residues
MHERWPQRVAPDGRKMNMTIALKSASAGSRALVYVSLAAVIEGFDLQAAGIAAPKIGPAFHMTPQQMGLFFSAATFGLMF
GALVGGYTADRWGRRAGLVIALAAFGVASIATIFSTSVEMLIALRFLTGVGLGGALPNLVSIASEAVGPERKGRAVAIMY
AGMPLGAAVASLVALLDLHGGDWRSIFLVGGILPLLLVPFIYAGLPPLKTVASTSERKTPWTEVFRPDAMVTTVLLWSAF
FLGLMVVYLLMNWLPQLLVGQGFSRSEASLALILYSLGGTVGSLIGGRVLDGSQRVVAIGASFAFVAAALAMLGLLPPAL
ATMLVTVTLVGVGVLCVQSILYGIAPQCYPSEIRGTGVGVVVAVGRLGSMAGPLLAGVLVAQGSTPADVMLVLVPIILAC
GLGTLALVARRFRPALA
>Mature_417_residues
MHERWPQRVAPDGRKMNMTIALKSASAGSRALVYVSLAAVIEGFDLQAAGIAAPKIGPAFHMTPQQMGLFFSAATFGLMF
GALVGGYTADRWGRRAGLVIALAAFGVASIATIFSTSVEMLIALRFLTGVGLGGALPNLVSIASEAVGPERKGRAVAIMY
AGMPLGAAVASLVALLDLHGGDWRSIFLVGGILPLLLVPFIYAGLPPLKTVASTSERKTPWTEVFRPDAMVTTVLLWSAF
FLGLMVVYLLMNWLPQLLVGQGFSRSEASLALILYSLGGTVGSLIGGRVLDGSQRVVAIGASFAFVAAALAMLGLLPPAL
ATMLVTVTLVGVGVLCVQSILYGIAPQCYPSEIRGTGVGVVVAVGRLGSMAGPLLAGVLVAQGSTPADVMLVLVPIILAC
GLGTLALVARRFRPALA

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081723, Length=379, Percent_Identity=43.7994722955145, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI87082404, Length=397, Percent_Identity=24.6851385390428, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786229, Length=380, Percent_Identity=26.0526315789474, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788074, Length=362, Percent_Identity=25.9668508287293, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082231, Length=453, Percent_Identity=23.1788079470199, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789207, Length=219, Percent_Identity=28.310502283105, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082320, Length=438, Percent_Identity=23.972602739726, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19922616, Length=335, Percent_Identity=23.5820895522388, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43085; Mature: 43085

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHERWPQRVAPDGRKMNMTIALKSASAGSRALVYVSLAAVIEGFDLQAAGIAAPKIGPAF
CCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
HMTPQQMGLFFSAATFGLMFGALVGGYTADRWGRRAGLVIALAAFGVASIATIFSTSVEM
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALRFLTGVGLGGALPNLVSIASEAVGPERKGRAVAIMYAGMPLGAAVASLVALLDLHG
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
GDWRSIFLVGGILPLLLVPFIYAGLPPLKTVASTSERKTPWTEVFRPDAMVTTVLLWSAF
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHH
FLGLMVVYLLMNWLPQLLVGQGFSRSEASLALILYSLGGTVGSLIGGRVLDGSQRVVAIG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCEEECCCCEEEEEC
ASFAFVAAALAMLGLLPPALATMLVTVTLVGVGVLCVQSILYGIAPQCYPSEIRGTGVGV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHH
VVAVGRLGSMAGPLLAGVLVAQGSTPADVMLVLVPIILACGLGTLALVARRFRPALA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHERWPQRVAPDGRKMNMTIALKSASAGSRALVYVSLAAVIEGFDLQAAGIAAPKIGPAF
CCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
HMTPQQMGLFFSAATFGLMFGALVGGYTADRWGRRAGLVIALAAFGVASIATIFSTSVEM
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIALRFLTGVGLGGALPNLVSIASEAVGPERKGRAVAIMYAGMPLGAAVASLVALLDLHG
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
GDWRSIFLVGGILPLLLVPFIYAGLPPLKTVASTSERKTPWTEVFRPDAMVTTVLLWSAF
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHH
FLGLMVVYLLMNWLPQLLVGQGFSRSEASLALILYSLGGTVGSLIGGRVLDGSQRVVAIG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCEEECCCCEEEEEC
ASFAFVAAALAMLGLLPPALATMLVTVTLVGVGVLCVQSILYGIAPQCYPSEIRGTGVGV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHH
VVAVGRLGSMAGPLLAGVLVAQGSTPADVMLVLVPIILACGLGTLALVARRFRPALA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]