Click here to switch to the map view.

The map label for this gene is mhpR [H]

Identifier: 154244881

GI number: 154244881

Start: 1051117

End: 1051917

Strand: Reverse

Name: mhpR [H]

Synonym: Xaut_0931

Alternate gene names: 154244881

Gene position: 1051917-1051117 (Counterclockwise)

Preceding gene: 154244892

Following gene: 154244880

Centisome position: 19.81

GC content: 65.17

Gene sequence:

>801_bases
ATGGCGGGGGAGAGCCCCTACAAGAACGTGCGGGGGCTGAGCCGGGGGCTCGCGCTCCTCAACGTCCTCAACCGCATCGA
CGGCGGCGCCAACGTGGCGCGCCTTGCGGAGCAGACAAAGTTGCATCGCACCACGGTGCAACGTCTTCTGGAGACCTTGC
AGGCGGAAGGCTATGTCCGGCGCAGCGAGTCCGACGACCGATACTGCCTGAACCTTCGCGTGCGGGAACTCAGCGAAGGT
TTTCGCGACGAGCACTGGATTTCCGCCCTCGCCTCGCCGCTGCTGGGACAATTGCTCAAGGAGGTGGTCTGGCCGACGGA
CCTTTGCACCTTCGACGTGGACGCCATGGTGGTCCGCGAGACCACGCATCGCTTCAGCAAGCTCTCGTTTCACCGCTCCA
TGATCGGCCGGCGCCTCCCCATGCTCCAGACGGCAAGCGGCACGGCCTATCTGGCATTCTGCCCGCAGGAGGAGCGCGAG
AGCATCATCGACTTCCTGGCACGGCAACCAAAAATGGAGTGCCGGCTGGCCCGTGACCGGCCGGCGCTGGACGACCTGCT
GGCGCGCGTGGTGCAGCGGGGCTATGGCGACAACCACATGAACTGGACGGACGAGCCGAAGATGGCCGGCATCGCGCTTC
CCATCCGCGGCAGGCAGGGGCTCCTCGGCTGCCTGAGCGTCGTCTATGTCGCCTCGGCCATGACCACGGCGATGGCCGCC
TCGCGTTATCTGGAGTCTCTTCGCCGGACGGTGAAATCAATCGAGCGCGACGCGGCAGACAGTTTATTTCTGCAGCCATG
A

Upstream 100 bases:

>100_bases
CGCGTTTCCCGCGCATGCAGTGACCTCAGCGGGCACCACGCACCGGTGCAAGCTGCTGGGATTTTTGCGTTATGCTGGCG
AAAAAAGGGAGCGAAGCATC

Downstream 100 bases:

>100_bases
TAGATTTTACGGCAACGCGACGAAGTTCAGGTTCACGTTTAAAGCAAAAGCATCCCAGATGATCTGGAGCGTCACCTTCT
TCCCGCCCGATGCGCGGGTG

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MAGESPYKNVRGLSRGLALLNVLNRIDGGANVARLAEQTKLHRTTVQRLLETLQAEGYVRRSESDDRYCLNLRVRELSEG
FRDEHWISALASPLLGQLLKEVVWPTDLCTFDVDAMVVRETTHRFSKLSFHRSMIGRRLPMLQTASGTAYLAFCPQEERE
SIIDFLARQPKMECRLARDRPALDDLLARVVQRGYGDNHMNWTDEPKMAGIALPIRGRQGLLGCLSVVYVASAMTTAMAA
SRYLESLRRTVKSIERDAADSLFLQP

Sequences:

>Translated_266_residues
MAGESPYKNVRGLSRGLALLNVLNRIDGGANVARLAEQTKLHRTTVQRLLETLQAEGYVRRSESDDRYCLNLRVRELSEG
FRDEHWISALASPLLGQLLKEVVWPTDLCTFDVDAMVVRETTHRFSKLSFHRSMIGRRLPMLQTASGTAYLAFCPQEERE
SIIDFLARQPKMECRLARDRPALDDLLARVVQRGYGDNHMNWTDEPKMAGIALPIRGRQGLLGCLSVVYVASAMTTAMAA
SRYLESLRRTVKSIERDAADSLFLQP
>Mature_265_residues
AGESPYKNVRGLSRGLALLNVLNRIDGGANVARLAEQTKLHRTTVQRLLETLQAEGYVRRSESDDRYCLNLRVRELSEGF
RDEHWISALASPLLGQLLKEVVWPTDLCTFDVDAMVVRETTHRFSKLSFHRSMIGRRLPMLQTASGTAYLAFCPQEERES
IIDFLARQPKMECRLARDRPALDDLLARVVQRGYGDNHMNWTDEPKMAGIALPIRGRQGLLGCLSVVYVASAMTTAMAAS
RYLESLRRTVKSIERDAADSLFLQP

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=252, Percent_Identity=61.5079365079365, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1788131, Length=205, Percent_Identity=27.8048780487805, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30024; Mature: 29893

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGESPYKNVRGLSRGLALLNVLNRIDGGANVARLAEQTKLHRTTVQRLLETLQAEGYVR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
RSESDDRYCLNLRVRELSEGFRDEHWISALASPLLGQLLKEVVWPTDLCTFDVDAMVVRE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHH
TTHRFSKLSFHRSMIGRRLPMLQTASGTAYLAFCPQEERESIIDFLARQPKMECRLARDR
HHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCC
PALDDLLARVVQRGYGDNHMNWTDEPKMAGIALPIRGRQGLLGCLSVVYVASAMTTAMAA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SRYLESLRRTVKSIERDAADSLFLQP
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGESPYKNVRGLSRGLALLNVLNRIDGGANVARLAEQTKLHRTTVQRLLETLQAEGYVR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
RSESDDRYCLNLRVRELSEGFRDEHWISALASPLLGQLLKEVVWPTDLCTFDVDAMVVRE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHH
TTHRFSKLSFHRSMIGRRLPMLQTASGTAYLAFCPQEERESIIDFLARQPKMECRLARDR
HHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCC
PALDDLLARVVQRGYGDNHMNWTDEPKMAGIALPIRGRQGLLGCLSVVYVASAMTTAMAA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SRYLESLRRTVKSIERDAADSLFLQP
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]