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The map label for this gene is paaG [H]

Identifier: 154244853

GI number: 154244853

Start: 1005166

End: 1005996

Strand: Reverse

Name: paaG [H]

Synonym: Xaut_0903

Alternate gene names: 154244853

Gene position: 1005996-1005166 (Counterclockwise)

Preceding gene: 154244858

Following gene: 154244852

Centisome position: 18.95

GC content: 72.08

Gene sequence:

>831_bases
GTGGTCGCACGCCAGGCGGACACCTTGACGAGCGAACCGGCCGCAGCGCCGCCGGTGCTGCTCGTGGCGCAGCACGAGGG
CTGGGTGGAACTCACCCTCAACCGCCCCGACCGCCTCAACGCCTTCACCGAGGAGCTGCACCGCTCGCTTGCCGCAGCCC
TCGACGCGGCGGCGGATGACGCCTGCCGGGCGGTGCTCCTCACCGGGGCCGGGCGCGGCTTCTGCGCCGGGCAGGATCTC
GGCGACCGGGCGAAGGCTGAGGGCCCGCTCGATCTCGGCGCCACCATCGAGGCCTTCTACAATCCCCTCATCCGGCGCAT
CCGCGCCCTGCGCAAGCCGGTAGTGTGCGCGGTGAACGGGGTGGCGGCGGGGGCCGGCGCCAACATCGCGTTTGCCTGCG
ATATCGTGCTGGCGGCGCGGTCGGCGAAATTCATCCAGGCCTTCGCCAAGATCGGCCTCGTGCCGGATTCCGGCGGCACC
TTCTTCCTGCCCCGCCTCATCGGGGATGCCCGCGCCCGCGCCCTCATGCTGCTCGCCGAGCCGGTCAGCGCCGAAAAGGC
GGAAAGCTGGGGCCTGATCTGGAAGGCGGTGGACGACGCCGCGCTCATGGACGAGGCCCGCGCCCTCGCCTCCCATCTCG
CCAGCCAGCCCACGCAGGGCCTTGCCCTCACCAAGCAGGCGCTGAACGCTTCCGCCGGCAATGCTCTCGACGCCCAGCTC
GACCTGGAGCGCGACCTCCAGCGCGAGGCCGGCCGCACGCCGGACTATCGCGAAGGCGTTTCCGCCTTCATGGAAAAGCG
CCCGGCGCGCTTCTCGGGGCGGCGCGCATGA

Upstream 100 bases:

>100_bases
GGGCCTCGTCCTGTTGACAAGCCCGTCCCTTGCGCTAAAGATTAACCGATCGATCGGTTAATTCAAGAGGCTCGCAAGGG
CCCGGATCAGGGAGGATGAC

Downstream 100 bases:

>100_bases
ACACCCACGCCCCTCATCCCGTCCCGCCGCGCACGCCACAGGACACCGCGCGTCTAAGCGCGGAGGCCATGTGGGCCACC
GACCATGCGAGCCAGGGCCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVARQADTLTSEPAAAPPVLLVAQHEGWVELTLNRPDRLNAFTEELHRSLAAALDAAADDACRAVLLTGAGRGFCAGQDL
GDRAKAEGPLDLGATIEAFYNPLIRRIRALRKPVVCAVNGVAAGAGANIAFACDIVLAARSAKFIQAFAKIGLVPDSGGT
FFLPRLIGDARARALMLLAEPVSAEKAESWGLIWKAVDDAALMDEARALASHLASQPTQGLALTKQALNASAGNALDAQL
DLERDLQREAGRTPDYREGVSAFMEKRPARFSGRRA

Sequences:

>Translated_276_residues
MVARQADTLTSEPAAAPPVLLVAQHEGWVELTLNRPDRLNAFTEELHRSLAAALDAAADDACRAVLLTGAGRGFCAGQDL
GDRAKAEGPLDLGATIEAFYNPLIRRIRALRKPVVCAVNGVAAGAGANIAFACDIVLAARSAKFIQAFAKIGLVPDSGGT
FFLPRLIGDARARALMLLAEPVSAEKAESWGLIWKAVDDAALMDEARALASHLASQPTQGLALTKQALNASAGNALDAQL
DLERDLQREAGRTPDYREGVSAFMEKRPARFSGRRA
>Mature_276_residues
MVARQADTLTSEPAAAPPVLLVAQHEGWVELTLNRPDRLNAFTEELHRSLAAALDAAADDACRAVLLTGAGRGFCAGQDL
GDRAKAEGPLDLGATIEAFYNPLIRRIRALRKPVVCAVNGVAAGAGANIAFACDIVLAARSAKFIQAFAKIGLVPDSGGT
FFLPRLIGDARARALMLLAEPVSAEKAESWGLIWKAVDDAALMDEARALASHLASQPTQGLALTKQALNASAGNALDAQL
DLERDLQREAGRTPDYREGVSAFMEKRPARFSGRRA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=242, Percent_Identity=33.8842975206612, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI25453481, Length=212, Percent_Identity=29.2452830188679, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI51538573, Length=212, Percent_Identity=29.2452830188679, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4757966, Length=212, Percent_Identity=29.2452830188679, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI51538581, Length=212, Percent_Identity=29.2452830188679, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4757968, Length=214, Percent_Identity=29.9065420560748, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI49355787, Length=214, Percent_Identity=29.9065420560748, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4502327, Length=267, Percent_Identity=32.5842696629214, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI221307494, Length=204, Percent_Identity=30.3921568627451, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI221136756, Length=204, Percent_Identity=30.3921568627451, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI221136753, Length=204, Percent_Identity=30.3921568627451, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI70995211, Length=254, Percent_Identity=29.9212598425197, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=26.4227642276423, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI45643119, Length=215, Percent_Identity=25.1162790697674, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260275230, Length=215, Percent_Identity=25.1162790697674, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260274832, Length=215, Percent_Identity=25.1162790697674, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI116235487, Length=205, Percent_Identity=29.7560975609756, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI157694516, Length=220, Percent_Identity=25.9090909090909, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI213417737, Length=220, Percent_Identity=25.9090909090909, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20127408, Length=171, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI150378541, Length=258, Percent_Identity=28.2945736434109, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI68989263, Length=194, Percent_Identity=28.8659793814433, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=59.6899224806201, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=37.5, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=32.6848249027237, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=25.296442687747, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=34.156378600823, Blast_Score=128, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=31.8367346938775, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=26.4822134387352, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=284, Percent_Identity=26.7605633802817, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=187, Percent_Identity=32.0855614973262, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=252, Percent_Identity=26.5873015873016, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=229, Percent_Identity=27.0742358078603, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141363, Length=175, Percent_Identity=26.2857142857143, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=168, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=34.5679012345679, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=34.5679012345679, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=30.1960784313725, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24654903, Length=175, Percent_Identity=29.1428571428571, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=25.9842519685039, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357171, Length=235, Percent_Identity=30.6382978723404, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920382, Length=270, Percent_Identity=27.4074074074074, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650670, Length=274, Percent_Identity=26.6423357664234, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29193; Mature: 29193

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVARQADTLTSEPAAAPPVLLVAQHEGWVELTLNRPDRLNAFTEELHRSLAAALDAAADD
CCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ACRAVLLTGAGRGFCAGQDLGDRAKAEGPLDLGATIEAFYNPLIRRIRALRKPVVCAVNG
HHHEEEEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
VAAGAGANIAFACDIVLAARSAKFIQAFAKIGLVPDSGGTFFLPRLIGDARARALMLLAE
EECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHEEHEEEC
PVSAEKAESWGLIWKAVDDAALMDEARALASHLASQPTQGLALTKQALNASAGNALDAQL
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHH
DLERDLQREAGRTPDYREGVSAFMEKRPARFSGRRA
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVARQADTLTSEPAAAPPVLLVAQHEGWVELTLNRPDRLNAFTEELHRSLAAALDAAADD
CCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ACRAVLLTGAGRGFCAGQDLGDRAKAEGPLDLGATIEAFYNPLIRRIRALRKPVVCAVNG
HHHEEEEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
VAAGAGANIAFACDIVLAARSAKFIQAFAKIGLVPDSGGTFFLPRLIGDARARALMLLAE
EECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHEEHEEEC
PVSAEKAESWGLIWKAVDDAALMDEARALASHLASQPTQGLALTKQALNASAGNALDAQL
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHH
DLERDLQREAGRTPDYREGVSAFMEKRPARFSGRRA
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]