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The map label for this gene is arsC [H]

Identifier: 154244825

GI number: 154244825

Start: 974774

End: 975343

Strand: Direct

Name: arsC [H]

Synonym: Xaut_0875

Alternate gene names: 154244825

Gene position: 974774-975343 (Clockwise)

Preceding gene: 154244824

Following gene: 154244826

Centisome position: 18.36

GC content: 69.12

Gene sequence:

>570_bases
ATGCCTGACGCAAAATGCTCTGACGCAACTCTGCCTGGCGCCGCCACCGGGCACGTCTTCAACGTGCTGTTCCTGTGCAC
CGGCAATTCCGCGCGCTCGATCCTCGCCGAGAGCATCCTGAACAAGGACGGCGCGGGCCGCTTCCGGGCCTTTTCGGCCG
GCAGCCAGCCGAAGGGCGAGGTGAACCCCTATGCCCTCAAGGTGCTCAGCGCCCTCGACTATCCCGCCGAGGGCTTCCGC
TCCAAGAACTGGGCGGAGTTCGCGGCCCCCGACGCGCCGGTGATGGATTTCGTCTTCACCGTCTGCGACAACGCCGCCGG
CGAGACCTGCCCGCTCTGGCCCGGCCAGCCCATGACCGCCCATTGGGGCATCGAGGACCCCGCCGCGGTGGAGGGCACCG
ACATCCAGAAGGAGGCCGCCTTCGTCGCCGCCTTCCGCTATCTGAGGAACCGCATCTCGGTGTTCACCGCCCTGCCCATC
GCCAAGCTCGACCGGCTCGCGCTGGGCGCGCAGTTGCGGGAGATCGGCCGGCTCGACGGCTCCACCCACCCCCGCCCGGA
CGTTGCGTGA

Upstream 100 bases:

>100_bases
ATCGCCTTCCTCATGCGCGACTGCTGCCAGGGCCACCCCGAGGTGTGCGCCCCCGCCGTCGCCGCCTTGTCCTGCGCCTG
CGAACCCACCGGGGACACCC

Downstream 100 bases:

>100_bases
GGCCCGCCATGGACGTGATCATCTACCACAACCCCGCCTGCGGCACCTCGCGCAACACCCTGGCCATGATCCGCAACGCG
GGCATCGAGCCGCATGTCAT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MPDAKCSDATLPGAATGHVFNVLFLCTGNSARSILAESILNKDGAGRFRAFSAGSQPKGEVNPYALKVLSALDYPAEGFR
SKNWAEFAAPDAPVMDFVFTVCDNAAGETCPLWPGQPMTAHWGIEDPAAVEGTDIQKEAAFVAAFRYLRNRISVFTALPI
AKLDRLALGAQLREIGRLDGSTHPRPDVA

Sequences:

>Translated_189_residues
MPDAKCSDATLPGAATGHVFNVLFLCTGNSARSILAESILNKDGAGRFRAFSAGSQPKGEVNPYALKVLSALDYPAEGFR
SKNWAEFAAPDAPVMDFVFTVCDNAAGETCPLWPGQPMTAHWGIEDPAAVEGTDIQKEAAFVAAFRYLRNRISVFTALPI
AKLDRLALGAQLREIGRLDGSTHPRPDVA
>Mature_188_residues
PDAKCSDATLPGAATGHVFNVLFLCTGNSARSILAESILNKDGAGRFRAFSAGSQPKGEVNPYALKVLSALDYPAEGFRS
KNWAEFAAPDAPVMDFVFTVCDNAAGETCPLWPGQPMTAHWGIEDPAAVEGTDIQKEAAFVAAFRYLRNRISVFTALPIA
KLDRLALGAQLREIGRLDGSTHPRPDVA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 20194; Mature: 20063

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAKCSDATLPGAATGHVFNVLFLCTGNSARSILAESILNKDGAGRFRAFSAGSQPKGE
CCCCCCCCCCCCCCCHHHEEEEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
VNPYALKVLSALDYPAEGFRSKNWAEFAAPDAPVMDFVFTVCDNAAGETCPLWPGQPMTA
CCHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
HWGIEDPAAVEGTDIQKEAAFVAAFRYLRNRISVFTALPIAKLDRLALGAQLREIGRLDG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
STHPRPDVA
CCCCCCCCC
>Mature Secondary Structure 
PDAKCSDATLPGAATGHVFNVLFLCTGNSARSILAESILNKDGAGRFRAFSAGSQPKGE
CCCCCCCCCCCCCCHHHEEEEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
VNPYALKVLSALDYPAEGFRSKNWAEFAAPDAPVMDFVFTVCDNAAGETCPLWPGQPMTA
CCHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
HWGIEDPAAVEGTDIQKEAAFVAAFRYLRNRISVFTALPIAKLDRLALGAQLREIGRLDG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
STHPRPDVA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]