Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 154244826

GI number: 154244826

Start: 975340

End: 975777

Strand: Direct

Name: arsC [H]

Synonym: Xaut_0876

Alternate gene names: 154244826

Gene position: 975340-975777 (Clockwise)

Preceding gene: 154244825

Following gene: 154244827

Centisome position: 18.37

GC content: 69.86

Gene sequence:

>438_bases
GTGAGGCCCGCCATGGACGTGATCATCTACCACAACCCCGCCTGCGGCACCTCGCGCAACACCCTGGCCATGATCCGCAA
CGCGGGCATCGAGCCGCATGTCATCGAATACCTGAAGACACCGCCGTCGCGCACGCTGCTGGCCGAGCTGATCGCCCGCG
CCGGCCTCACGGTGCGCGGCGCGCTGCGGGAGAAGGGCACGCCCTATGCCGAGCTTGGCCTCGCCGATGAGGCGCTCTCC
GACGATGCCCTGCTCGATGCCATGATGGCCCATCCCATCCTCATCAACCGGCCGCTGGTGGTGTCGCCCAAGGGCGTGCG
CGTGTGCCGGCCGTCCGAGCTGGTGCTGGACCTGTTGCCGCCCCAGAAGGGCGCGTTCACCAAGGAAGACGGCGAACGGG
TGGTGGACGCCGCCGGCCAGCCCGTTGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCGCCCTGCCCATCGCCAAGCTCGACCGGCTCGCGCTGGGCGCGCAGTTGCGGGAGATCGGCCGGCTCGACGGCTCCACC
CACCCCCGCCCGGACGTTGC

Downstream 100 bases:

>100_bases
CGCACGGCAGAGAGATTTCAATCATGTCCATCTTTGAACGGTTCCTCACCGTCTGGGTCGGCCTGTGCATCATCGTGGGC
ATCGCGCTCGGCCATCTGGC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRPAMDVIIYHNPACGTSRNTLAMIRNAGIEPHVIEYLKTPPSRTLLAELIARAGLTVRGALREKGTPYAELGLADEALS
DDALLDAMMAHPILINRPLVVSPKGVRVCRPSELVLDLLPPQKGAFTKEDGERVVDAAGQPVAAG

Sequences:

>Translated_145_residues
MRPAMDVIIYHNPACGTSRNTLAMIRNAGIEPHVIEYLKTPPSRTLLAELIARAGLTVRGALREKGTPYAELGLADEALS
DDALLDAMMAHPILINRPLVVSPKGVRVCRPSELVLDLLPPQKGAFTKEDGERVVDAAGQPVAAG
>Mature_145_residues
MRPAMDVIIYHNPACGTSRNTLAMIRNAGIEPHVIEYLKTPPSRTLLAELIARAGLTVRGALREKGTPYAELGLADEALS
DDALLDAMMAHPILINRPLVVSPKGVRVCRPSELVLDLLPPQKGAFTKEDGERVVDAAGQPVAAG

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=136, Percent_Identity=63.2352941176471, Blast_Score=186, Evalue=5e-49,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=42.9824561403509, Blast_Score=97, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15499; Mature: 15499

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAMDVIIYHNPACGTSRNTLAMIRNAGIEPHVIEYLKTPPSRTLLAELIARAGLTVRG
CCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEE
ALREKGTPYAELGLADEALSDDALLDAMMAHPILINRPLVVSPKGVRVCRPSELVLDLLP
HHHHCCCCHHHHCCCHHHCCHHHHHHHHHHCCEEECCCEEECCCCCEEECHHHHHHCCCC
PQKGAFTKEDGERVVDAAGQPVAAG
CCCCCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MRPAMDVIIYHNPACGTSRNTLAMIRNAGIEPHVIEYLKTPPSRTLLAELIARAGLTVRG
CCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEE
ALREKGTPYAELGLADEALSDDALLDAMMAHPILINRPLVVSPKGVRVCRPSELVLDLLP
HHHHCCCCHHHHCCCHHHCCHHHHHHHHHHCCEEECCCEEECCCCCEEECHHHHHHCCCC
PQKGAFTKEDGERVVDAAGQPVAAG
CCCCCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]