Click here to switch to the map view.

The map label for this gene is gltS [H]

Identifier: 154244781

GI number: 154244781

Start: 929973

End: 931181

Strand: Direct

Name: gltS [H]

Synonym: Xaut_0831

Alternate gene names: 154244781

Gene position: 929973-931181 (Clockwise)

Preceding gene: 154244780

Following gene: 154244782

Centisome position: 17.52

GC content: 67.91

Gene sequence:

>1209_bases
ATGCCAGCCACCTTTGAGGTCTCGGGCTTCCTCACCTTCACCCTCGCCATCGTGGTGTATTTCATCGGCGCCGGCCTCAA
CGGCGTGATCGCCCCGCTGCGTCGCTGGAACATTCCGGAGGCGGTCACCGGCGGCCTCCTGGCGGCGGTGGCGACGCTCG
TGTGCTATCGCGTGCTCGGCCTTGCCATCTCGTTCGACCTCGCTGCGCGCGACATGCTGCTTTTGTATTTCTTCACCGGC
ATCGGCCTCAATGCGCGCCTGTCGGACCTGGTGCTGGGCGGGCGGCCGCTGCTCATCCTGCTGCTTCTGACTGTGGTCTA
TCTCGGGCTGCAGAATGTGGTGGCCATCGGCGGGGCCAAGGCGCTGGGCCTGCCCGACGGCATCGCCCCGCTGCTGGGCT
CGGTGTCGCTCATCGGCGGGCACGGCACCACCATCGCCTGGGCTCCGCTGATCTCCGAGCGCTTCGGCCTGCCCAATGCC
CTGGAAGTGGGCATCGCCAGCGCCACCCTGGGCCTCGTCATCGCCAGCCTCGTGGGCGGGCCGGTGGCGGGCATCCTCAT
CAACCGCTTCAAGCTGCGCAGCGACGAGATCCTGGCCCCCATGGTGGGCCTGCCCGACGACGACGTGGGGCCGGACGCGG
GCAAGGTGACCTATCGCAACATCCTGAGCGCGCTTCTGGTGCTCAACGTGGTGATCCTCACCGCGTATTCGCTGGAAGGG
CTGGTGGAGCAGACCGGCATCAAGCTGCCCCTGTTCGTGGTGTGCCTGCTGGTGGCCATCGTCATCACCAACACGCTGCC
CCATGCCCTGCCGCGCATGACGTGGCCGGCGCGCACGCCGGCGCTGGCGCTCATCTCCGACCTGTCGCTGAAGATCTTCC
TCGCCATGTCGCTCATGAGCATGCAGCTGTGGACTCTGGGCGGGCTCGGGCCGGCGCTGGCCGTGGTGCTCGGGCTGCAG
ACGCTGGTGGCGGTGCTCTACATCCTGTTCGCGGTGTTTCCGGCAATGGGGCGCAACTACCAGGCGGCGGTGCTGGCGGC
GGGCTTCACCGGCATCAGCCTTGGGGCGACGCCCACCGCCATCGCCAACATGACGGCGGTGACGCGTACCCACGGGCCGG
CGCCCATCGCCTTCATCATCCTGCCGCTGGTGTCGGCCTTCTTCATCGACATCGCCAACGCCCTCGCCATCGGCTTCATG
CTGCGCTGA

Upstream 100 bases:

>100_bases
AGGCTTTGTGCTTTCCGCCCGGCGCGTCTAGAGCATACCGGCGGCGGTTGGGCCGCCGTCCAATGAAACCATCACACCAG
CCGGAACTGCGGGGGAAGAC

Downstream 100 bases:

>100_bases
GGGCGGGCGCGCCTGGAGCATCAGCGCCGGGCGCCATCTGCATTCATGAAAGGCCAGGCGCGGGTGCGGTGGTCCTGCCG
CGCATGCTTAGCCGTGGGCG

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPATFEVSGFLTFTLAIVVYFIGAGLNGVIAPLRRWNIPEAVTGGLLAAVATLVCYRVLGLAISFDLAARDMLLLYFFTG
IGLNARLSDLVLGGRPLLILLLLTVVYLGLQNVVAIGGAKALGLPDGIAPLLGSVSLIGGHGTTIAWAPLISERFGLPNA
LEVGIASATLGLVIASLVGGPVAGILINRFKLRSDEILAPMVGLPDDDVGPDAGKVTYRNILSALLVLNVVILTAYSLEG
LVEQTGIKLPLFVVCLLVAIVITNTLPHALPRMTWPARTPALALISDLSLKIFLAMSLMSMQLWTLGGLGPALAVVLGLQ
TLVAVLYILFAVFPAMGRNYQAAVLAAGFTGISLGATPTAIANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFM
LR

Sequences:

>Translated_402_residues
MPATFEVSGFLTFTLAIVVYFIGAGLNGVIAPLRRWNIPEAVTGGLLAAVATLVCYRVLGLAISFDLAARDMLLLYFFTG
IGLNARLSDLVLGGRPLLILLLLTVVYLGLQNVVAIGGAKALGLPDGIAPLLGSVSLIGGHGTTIAWAPLISERFGLPNA
LEVGIASATLGLVIASLVGGPVAGILINRFKLRSDEILAPMVGLPDDDVGPDAGKVTYRNILSALLVLNVVILTAYSLEG
LVEQTGIKLPLFVVCLLVAIVITNTLPHALPRMTWPARTPALALISDLSLKIFLAMSLMSMQLWTLGGLGPALAVVLGLQ
TLVAVLYILFAVFPAMGRNYQAAVLAAGFTGISLGATPTAIANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFM
LR
>Mature_401_residues
PATFEVSGFLTFTLAIVVYFIGAGLNGVIAPLRRWNIPEAVTGGLLAAVATLVCYRVLGLAISFDLAARDMLLLYFFTGI
GLNARLSDLVLGGRPLLILLLLTVVYLGLQNVVAIGGAKALGLPDGIAPLLGSVSLIGGHGTTIAWAPLISERFGLPNAL
EVGIASATLGLVIASLVGGPVAGILINRFKLRSDEILAPMVGLPDDDVGPDAGKVTYRNILSALLVLNVVILTAYSLEGL
VEQTGIKLPLFVVCLLVAIVITNTLPHALPRMTWPARTPALALISDLSLKIFLAMSLMSMQLWTLGGLGPALAVVLGLQT
LVAVLYILFAVFPAMGRNYQAAVLAAGFTGISLGATPTAIANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFML
R

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=386, Percent_Identity=41.1917098445596, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 41864; Mature: 41733

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATFEVSGFLTFTLAIVVYFIGAGLNGVIAPLRRWNIPEAVTGGLLAAVATLVCYRVLG
CCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAISFDLAARDMLLLYFFTGIGLNARLSDLVLGGRPLLILLLLTVVYLGLQNVVAIGGAK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ALGLPDGIAPLLGSVSLIGGHGTTIAWAPLISERFGLPNALEVGIASATLGLVIASLVGG
CCCCCCCHHHHHCCCEEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
PVAGILINRFKLRSDEILAPMVGLPDDDVGPDAGKVTYRNILSALLVLNVVILTAYSLEG
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEQTGIKLPLFVVCLLVAIVITNTLPHALPRMTWPARTPALALISDLSLKIFLAMSLMS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MQLWTLGGLGPALAVVLGLQTLVAVLYILFAVFPAMGRNYQAAVLAAGFTGISLGATPTA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCHH
IANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFMLR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PATFEVSGFLTFTLAIVVYFIGAGLNGVIAPLRRWNIPEAVTGGLLAAVATLVCYRVLG
CCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAISFDLAARDMLLLYFFTGIGLNARLSDLVLGGRPLLILLLLTVVYLGLQNVVAIGGAK
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ALGLPDGIAPLLGSVSLIGGHGTTIAWAPLISERFGLPNALEVGIASATLGLVIASLVGG
CCCCCCCHHHHHCCCEEECCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
PVAGILINRFKLRSDEILAPMVGLPDDDVGPDAGKVTYRNILSALLVLNVVILTAYSLEG
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEQTGIKLPLFVVCLLVAIVITNTLPHALPRMTWPARTPALALISDLSLKIFLAMSLMS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MQLWTLGGLGPALAVVLGLQTLVAVLYILFAVFPAMGRNYQAAVLAAGFTGISLGATPTA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCHH
IANMTAVTRTHGPAPIAFIILPLVSAFFIDIANALAIGFMLR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]