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The map label for this gene is sucC [H]

Identifier: 154244112

GI number: 154244112

Start: 148592

End: 149794

Strand: Direct

Name: sucC [H]

Synonym: Xaut_0154

Alternate gene names: 154244112

Gene position: 148592-149794 (Clockwise)

Preceding gene: 154244111

Following gene: 154244113

Centisome position: 2.8

GC content: 63.67

Gene sequence:

>1203_bases
ATGAATATTCACGAGTACCAGGCCAAGGCGCTGCTGAAGAAGTACGGCGCGCCGGTCTCGCGCGGCGTGCCCGTGTTGAA
GGTGGAAGATGCCGAGGCGGCGGCCAAGGAGCTCGGCGGTCCGCTCTGGGTGGTGAAGTCCCAGATCCATGCGGGCGGCC
GTGGCAAGGGCAAGTTCAAGGAGCCCGAGGCCGGCGACAAGGGCGGCGTGCGCCTCGCCAAGTCCATCGACGAGGTGAAG
ACCTTCGTCTCGCAGATGCTGGGCAACACGCTCGTCACCATCCAGACCGGCCCCGCCGGCAAGCAGGTGAACCGCCTGTA
TCTGGAAGACGGCTCCGACATCGAGAAGGAGTTCTACATCTCCCTGCTCGTGGATCGCGCCACCTCCCACGTGGCCTTCG
TGGTCTCCACTGAAGGTGGCATGGACATCGAGGAAGTGGCCCACTCCCACCCGGAGAAGATCGTCACCTTCTCGGTGGAT
CCGGTTACCGGCGTGCAGGGCTTCCACGGCCGCAAGATCGCCAAGGCCCTGGGCCTCACGGGCGACCTGGCCAAGCAGGC
GGGCAAGCTCGCCGAGGTGCTCTATACGGCCTTCGTCGATACCGACATGGCGATGCTCGAGATCAACCCGCTGATCATCA
CCAAGGATGCCCAGCTGCGCGTGCTCGACGCCAAGGTCACCTTCGATTCCAACGCCATGTTCCGCCATCCGGAGCTCGCC
GAGCTGCGCGATCTGACGGAAGAGGACGCCAAGGAAATCGAGGCCTCCAAGTACGACCTCGCCTATATCGCGCTTGATGG
CACCATCGGCTGCATGGTCAACGGCGCCGGCCTCGCCATGGCGACCCTCGACATCATCCAGCTCTACGGCGAAAGCCCGG
CCAACTTCCTGGACGTGGGCGGTGGCGCCAATGAGGAGAAGGTGACGGCCGCCTTCAAGATCATCACTGCCGATCCGAAC
GTGAAGGGCATCCTCGTCAACATCTTCGGCGGCATCATGCAGTGCGACGTGATCGCGCGCGGCGTGCTGGCGGCGGTGAA
GGCGGTGGGCCTTGAAGTTCCGCTGGTGGTGCGCCTCGAAGGCACCAACGTGGAAGAAGGCAAGAAGATCATCCGTGAGA
GTGGTCTGAACGTGATCCCGGCGGATGACCTCGATGACGCGGCGCAGAAGATTGTCGCGGCCGTGAAGAAGGAAGCTGCG
TGA

Upstream 100 bases:

>100_bases
CTGCGGTGGAAGCGGCGCGGACCATCTGGCCCCGCATTTTGCGGGGCGCGGTCCGTCCGGGGCGGGGGAGGGGCGTTTCG
CAACCCTGAGGGACGCAGAG

Downstream 100 bases:

>100_bases
TGTCCGTGCTTATCGACGCCAATACCCGTGTCATCACCCAGGGCTTCACCGGCAAGAACGGCACCTTCCACGCCCAGCAG
GCCATTGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNIHEYQAKALLKKYGAPVSRGVPVLKVEDAEAAAKELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLAKSIDEVK
TFVSQMLGNTLVTIQTGPAGKQVNRLYLEDGSDIEKEFYISLLVDRATSHVAFVVSTEGGMDIEEVAHSHPEKIVTFSVD
PVTGVQGFHGRKIAKALGLTGDLAKQAGKLAEVLYTAFVDTDMAMLEINPLIITKDAQLRVLDAKVTFDSNAMFRHPELA
ELRDLTEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIQLYGESPANFLDVGGGANEEKVTAAFKIITADPN
VKGILVNIFGGIMQCDVIARGVLAAVKAVGLEVPLVVRLEGTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA

Sequences:

>Translated_400_residues
MNIHEYQAKALLKKYGAPVSRGVPVLKVEDAEAAAKELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLAKSIDEVK
TFVSQMLGNTLVTIQTGPAGKQVNRLYLEDGSDIEKEFYISLLVDRATSHVAFVVSTEGGMDIEEVAHSHPEKIVTFSVD
PVTGVQGFHGRKIAKALGLTGDLAKQAGKLAEVLYTAFVDTDMAMLEINPLIITKDAQLRVLDAKVTFDSNAMFRHPELA
ELRDLTEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIQLYGESPANFLDVGGGANEEKVTAAFKIITADPN
VKGILVNIFGGIMQCDVIARGVLAAVKAVGLEVPLVVRLEGTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA
>Mature_400_residues
MNIHEYQAKALLKKYGAPVSRGVPVLKVEDAEAAAKELGGPLWVVKSQIHAGGRGKGKFKEPEAGDKGGVRLAKSIDEVK
TFVSQMLGNTLVTIQTGPAGKQVNRLYLEDGSDIEKEFYISLLVDRATSHVAFVVSTEGGMDIEEVAHSHPEKIVTFSVD
PVTGVQGFHGRKIAKALGLTGDLAKQAGKLAEVLYTAFVDTDMAMLEINPLIITKDAQLRVLDAKVTFDSNAMFRHPELA
ELRDLTEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIQLYGESPANFLDVGGGANEEKVTAAFKIITADPN
VKGILVNIFGGIMQCDVIARGVLAAVKAVGLEVPLVVRLEGTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=43.6224489795918, Blast_Score=338, Evalue=4e-93,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=46.3730569948187, Blast_Score=331, Evalue=6e-91,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=45.9016393442623, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=50.7575757575758, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17539378, Length=397, Percent_Identity=44.080604534005, Blast_Score=334, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=45.4314720812183, Blast_Score=333, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=43.5443037974684, Blast_Score=333, Evalue=3e-92,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=47.9899497487437, Blast_Score=345, Evalue=2e-95,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=48.4536082474227, Blast_Score=344, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=48.4536082474227, Blast_Score=344, Evalue=7e-95,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=48.5933503836317, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=48.5933503836317, Blast_Score=342, Evalue=3e-94,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42620; Mature: 42620

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKKYGAPVSRGVPVLKVEDAEAAAKELGGPLWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHHCCCEEEECCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
EPEAGDKGGVRLAKSIDEVKTFVSQMLGNTLVTIQTGPAGKQVNRLYLEDGSDIEKEFYI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHH
SLLVDRATSHVAFVVSTEGGMDIEEVAHSHPEKIVTFSVDPVTGVQGFHGRKIAKALGLT
HHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCC
GDLAKQAGKLAEVLYTAFVDTDMAMLEINPLIITKDAQLRVLDAKVTFDSNAMFRHPELA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCEEEEEEEEEEECCCCCCCCCCHH
ELRDLTEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIQLYGESPANFLDVG
HHHHCHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGANEEKVTAAFKIITADPNVKGILVNIFGGIMQCDVIARGVLAAVKAVGLEVPLVVRLE
CCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA
CCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLKKYGAPVSRGVPVLKVEDAEAAAKELGGPLWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHHCCCEEEECCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
EPEAGDKGGVRLAKSIDEVKTFVSQMLGNTLVTIQTGPAGKQVNRLYLEDGSDIEKEFYI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHH
SLLVDRATSHVAFVVSTEGGMDIEEVAHSHPEKIVTFSVDPVTGVQGFHGRKIAKALGLT
HHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHCCC
GDLAKQAGKLAEVLYTAFVDTDMAMLEINPLIITKDAQLRVLDAKVTFDSNAMFRHPELA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCEEEEEEEEEEECCCCCCCCCCHH
ELRDLTEEDAKEIEASKYDLAYIALDGTIGCMVNGAGLAMATLDIIQLYGESPANFLDVG
HHHHCHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGANEEKVTAAFKIITADPNVKGILVNIFGGIMQCDVIARGVLAAVKAVGLEVPLVVRLE
CCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GTNVEEGKKIIRESGLNVIPADDLDDAAQKIVAAVKKEAA
CCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA