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The map label for this gene is rnd [H]

Identifier: 154244026

GI number: 154244026

Start: 73947

End: 74567

Strand: Reverse

Name: rnd [H]

Synonym: Xaut_0068

Alternate gene names: 154244026

Gene position: 74567-73947 (Counterclockwise)

Preceding gene: 154244028

Following gene: 154244025

Centisome position: 1.4

GC content: 68.12

Gene sequence:

>621_bases
ATGACCATCCGCCTGCATCGCGGCGACCTGCCCGCGGACTTCGTCGCCGCGCCCGTGGTGGCGATCGACACCGAGACCAT
GGGGCTCAACCCCTTCCGCGACCGGCTTTGCCTGGTCCAGCTGTCCAACGGCGACGGAAGCGCCGACCTGGTGCAGATCC
CGCAGGGCGCCGACGCCACCACCGCGCCGAACCTCACGCGCCTTTTGGCCGATCCCGCCATCACCAAGCTGTTCCATTTC
GGACGGTTCGATATCGCGGTGCTCCAGCACACCTTCCATGTGATGCCGCAGCCGGTGTGGTGCACCAAGATCGCCTCGCG
GCTGGTGCGCACCTACACCGACCGCCACGGGCTGAAGGACCTGCTGCGCGAGACCATCAACGTGGACATCTCCAAGCAGC
AGCAGAGCTCCGATTGGGGCGCCAAGGACCTCTCCGACGCCCAGCTCGCCTATGCCGCTTCCGACGTGCTGCACCTGCAT
GCGGTGAAGGCCAAGCTGGAGGAGATGCTGGCGCGGGAGAACCGCACCGGGCTCGCCGCCGCCTGCTTCGCCTTCCTGCC
GGCGCGGGCGGCCCTCGACCTCTCGGGCTGGGCGGAAGAGGACATCTTCGCCCACTCCTGA

Upstream 100 bases:

>100_bases
GCCGTCGTGTCCCGCATGGGAGCCGCCGCCGCACGGCCATCGACAGGGGCGCCGTGCTTCGCTAAAAGCCGTGGCGATCC
AGAAAGATAAAGACGCACCG

Downstream 100 bases:

>100_bases
GCCGGCAACCTTTATAAAAATCAAACGCTGGCAAGGTCTTCCGGCCGGGCCTTGCACCGGCTCGCCATTTCGGACAATTT
GGCCGGGTGCGTGGGGCGAC

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTIRLHRGDLPADFVAAPVVAIDTETMGLNPFRDRLCLVQLSNGDGSADLVQIPQGADATTAPNLTRLLADPAITKLFHF
GRFDIAVLQHTFHVMPQPVWCTKIASRLVRTYTDRHGLKDLLRETINVDISKQQQSSDWGAKDLSDAQLAYAASDVLHLH
AVKAKLEEMLARENRTGLAAACFAFLPARAALDLSGWAEEDIFAHS

Sequences:

>Translated_206_residues
MTIRLHRGDLPADFVAAPVVAIDTETMGLNPFRDRLCLVQLSNGDGSADLVQIPQGADATTAPNLTRLLADPAITKLFHF
GRFDIAVLQHTFHVMPQPVWCTKIASRLVRTYTDRHGLKDLLRETINVDISKQQQSSDWGAKDLSDAQLAYAASDVLHLH
AVKAKLEEMLARENRTGLAAACFAFLPARAALDLSGWAEEDIFAHS
>Mature_205_residues
TIRLHRGDLPADFVAAPVVAIDTETMGLNPFRDRLCLVQLSNGDGSADLVQIPQGADATTAPNLTRLLADPAITKLFHFG
RFDIAVLQHTFHVMPQPVWCTKIASRLVRTYTDRHGLKDLLRETINVDISKQQQSSDWGAKDLSDAQLAYAASDVLHLHA
VKAKLEEMLARENRTGLAAACFAFLPARAALDLSGWAEEDIFAHS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=169, Percent_Identity=33.1360946745562, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 22627; Mature: 22496

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRLHRGDLPADFVAAPVVAIDTETMGLNPFRDRLCLVQLSNGDGSADLVQIPQGADAT
CEEEEECCCCCHHHHHCCEEEECCCCCCCCHHHCCEEEEEECCCCCCCEEEECCCCCCCC
TAPNLTRLLADPAITKLFHFGRFDIAVLQHTFHVMPQPVWCTKIASRLVRTYTDRHGLKD
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LLRETINVDISKQQQSSDWGAKDLSDAQLAYAASDVLHLHAVKAKLEEMLARENRTGLAA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ACFAFLPARAALDLSGWAEEDIFAHS
HHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIRLHRGDLPADFVAAPVVAIDTETMGLNPFRDRLCLVQLSNGDGSADLVQIPQGADAT
EEEEECCCCCHHHHHCCEEEECCCCCCCCHHHCCEEEEEECCCCCCCEEEECCCCCCCC
TAPNLTRLLADPAITKLFHFGRFDIAVLQHTFHVMPQPVWCTKIASRLVRTYTDRHGLKD
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LLRETINVDISKQQQSSDWGAKDLSDAQLAYAASDVLHLHAVKAKLEEMLARENRTGLAA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ACFAFLPARAALDLSGWAEEDIFAHS
HHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]