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The map label for this gene is aaeR [H]

Identifier: 153950653

GI number: 153950653

Start: 495481

End: 496392

Strand: Reverse

Name: aaeR [H]

Synonym: YpsIP31758_0418

Alternate gene names: 153950653

Gene position: 496392-495481 (Counterclockwise)

Preceding gene: 153947515

Following gene: 153947294

Centisome position: 10.51

GC content: 48.25

Gene sequence:

>912_bases
ATGGAAAGATTAAAACAGATGTCTGTTTTTGCGAAGGTGGTGGAGTGCGGTTCTTTTACTGCCGCAGCACGACGACTGGA
GAACAGTGTCTCTTCGATCAGCCAAACGGTATCAAAACTGGAAAATGAGCTTAACGTTAAGCTACTAAATCGTAGTACTC
GCCGCATTGGCTTAACGGAAGCGGGCCGGATTTATTACCAAGGCTGCCGGCGTATGTTGCAGGAGGTGCAGCAAGTTCAC
GAACAATTGTATGCTTTTAATAATACGCCAACCGGCACATTGCGTATTGGTTGCTCCTCCACCATGGCACAAAATGTGCT
GGCCACCATGACAGCCGATATGCTCAAAGCCTATCCTGGTTTATCAGTAAATCTGGTTACCGGTATTCCTGCGCCGGACC
TGATAGCTGATGGCCTGGATGTGGTGATCCGCGTCGGTGCCTTGCAAAATTCAGGTCTGTTTTCGCGCCGCCTCGGGGCT
ATGCCGATGGTGGTGTGTGCAGCAAAAAGCTATTTGTCACAATATGGCACGCCAGAAAAGCCCGGTGACATGGCCAATTA
TTCCTGGTTGGAGTATAACGTCCGCCCAGACAGCAATTTTGAGCTGATTGCACCAGAAGGTATCACCACCCAAATATCAC
CGCAGGGTCGCTTTGTCACCAATGACTCACAAACCATGATCCGTTGGTTAAAGGCCGGGGCGGGTATCGCCTATGCTCCC
TTAATGTGGGTGATTGAAGAAATTAAACGTGGCGAGGTTGAGATTCTATTTAAACACTATCACTCCGACCCGCGCCCGGT
ATATGCGCTTTATACTGAAAAAGATAAAATGCCCCTAAAAGTTCAGGTCTGCATTGATTATCTGACTGAGTATTTCAAAC
GGGTCGCTGAAGTTTATCAGGATTATCGCTAA

Upstream 100 bases:

>100_bases
TCCCGACAACAGTATATTAGCCTGCTTATTATCAAGTTATCTACGATGTGTGATCTAAATCACTTTTAAGCCCGAGTTAA
TAATACAGATGGAATAAGTA

Downstream 100 bases:

>100_bases
CGGTATGTTATATCAAATAATAAATTACCCTGATGATTTGAAATCATCTTAAAATAAGAAACAACTGTTAAATAAGATAT
TTATTATGGTAATTTACGTA

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MERLKQMSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTEAGRIYYQGCRRMLQEVQQVH
EQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQNSGLFSRRLGA
MPMVVCAAKSYLSQYGTPEKPGDMANYSWLEYNVRPDSNFELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYAP
LMWVIEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRVAEVYQDYR

Sequences:

>Translated_303_residues
MERLKQMSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTEAGRIYYQGCRRMLQEVQQVH
EQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQNSGLFSRRLGA
MPMVVCAAKSYLSQYGTPEKPGDMANYSWLEYNVRPDSNFELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYAP
LMWVIEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRVAEVYQDYR
>Mature_303_residues
MERLKQMSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTEAGRIYYQGCRRMLQEVQQVH
EQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQNSGLFSRRLGA
MPMVVCAAKSYLSQYGTPEKPGDMANYSWLEYNVRPDSNFELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYAP
LMWVIEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRVAEVYQDYR

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=301, Percent_Identity=81.3953488372093, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=28.6195286195286, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=31.0344827586207, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI87081978, Length=302, Percent_Identity=30.794701986755, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=26.7361111111111, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=25.5972696245734, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=26.2773722627737, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=33.8842975206612, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=147, Percent_Identity=31.9727891156463, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788706, Length=141, Percent_Identity=31.2056737588652, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=24.4, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=114, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34078; Mature: 34078

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLKQMSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHEECCCH
AGRIYYQGCRRMLQEVQQVHEQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
LSVNLVTGIPAPDLIADGLDVVIRVGALQNSGLFSRRLGAMPMVVCAAKSYLSQYGTPEK
CEEEEEECCCCHHHHHCCHHHHHEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCC
PGDMANYSWLEYNVRPDSNFELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYAP
CCCCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCEEECCHHHHHHHHHHCCCHHHHH
LMWVIEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRVAEVYQ
HHHHHHHHCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DYR
CCC
>Mature Secondary Structure
MERLKQMSVFAKVVECGSFTAAARRLENSVSSISQTVSKLENELNVKLLNRSTRRIGLTE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHEECCCH
AGRIYYQGCRRMLQEVQQVHEQLYAFNNTPTGTLRIGCSSTMAQNVLATMTADMLKAYPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
LSVNLVTGIPAPDLIADGLDVVIRVGALQNSGLFSRRLGAMPMVVCAAKSYLSQYGTPEK
CEEEEEECCCCHHHHHCCHHHHHEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCC
PGDMANYSWLEYNVRPDSNFELIAPEGITTQISPQGRFVTNDSQTMIRWLKAGAGIAYAP
CCCCCCCCEEEEECCCCCCCEEECCCCCEEEECCCCCEEECCHHHHHHHHHHCCCHHHHH
LMWVIEEIKRGEVEILFKHYHSDPRPVYALYTEKDKMPLKVQVCIDYLTEYFKRVAEVYQ
HHHHHHHHCCCCCEEHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DYR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]