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The map label for this gene is rhaR

Identifier: 153950236

GI number: 153950236

Start: 4227804

End: 4228676

Strand: Reverse

Name: rhaR

Synonym: YpsIP31758_3753

Alternate gene names: 153950236

Gene position: 4228676-4227804 (Counterclockwise)

Preceding gene: 153947203

Following gene: 153947551

Centisome position: 89.53

GC content: 49.26

Gene sequence:

>873_bases
ATGCGGGCACCACTGCTGTTAGAAAGCCGGGATTATTTACTCTCGGAACAGATGCCGGTGGCGGTAACCAATCGATACCC
GCAGGAAACCTTCGTAGAGCATACCCATCAATTTTGTGAAATTGTGATTGTCTGGCGGGGAAATGGCTTACATGTCCTGA
ATGACCACCCTTATCGCATTACCTGTGGGGACGTTTTTTATATTCAAGCCGCAGACCATCATAGCTACGAATCCGTACAT
GATTTGGTATTAGATAATATTATCTATTGCCCAGAGCGACTCCACCTGAATGCGCAATGGCATAAGTTACTGCCGCCTTT
GGGACCTGAACAGAATCAGGGCTATTGGCGGTTAACGACACAAGGCATGGCGCAGGCACGGCCCATCATTCAACAGTTGG
CGCAGGAATCGCGCAAGACGGATTCCTGGTCGATACAACTGACTGAAGTCCTGTTATTGCAACTTGCCATTGTGCTGAAA
CGCCATCGCTATAGAGCTGAACACGCTCACTTACTGCCCGATGGCGAGCAGCTTGATTTAATCATGTCTGCGTTGCAGCA
AAGTCTGGGAGCCTATTTTGATATGGCTGATTTCTGCCATAAAAATCAGTTGGTTGAACGTTCTCTCAAGCAACTGTTCC
GCCAGCAGACCGGCATGAGTATCAGCCACTACCTACGCCAGATTCGCTTGTGTCATGCCAAGTGTTTATTACGCGGCAGT
GAGCATCGTATCAGTGATATCGCCGCTCGCTGTGGGTTTGAGGACAGTAACTATTTCTCGGCTGTTTTTACCCGTGAAGC
CGGTATGACCCCACGAGATTATCGCCAGCGCTTTATCCGCTCCCCGGTATTACCCGCTAAAAATGAACCGTGA

Upstream 100 bases:

>100_bases
AGGGTATTACGGTAAAAATTGAAGGGTATCACGGTAAAAATTGGCCGTTTCAAGATAATGAACAAGTCATTAATTAACCT
ATAACGATAAGGCTGCACAC

Downstream 100 bases:

>100_bases
TAACCACAGCGATCTCATTTAGCATTATTCTTCACCACGATTAGCCATAAGATAACGGGCAGGTTTTTCAACGCTGCCCG
TCAATATCATCATCTTTAAT

Product: transcriptional activator RhaR

Products: NA

Alternate protein names: L-rhamnose operon transcriptional activator rhaR

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRAPLLLESRDYLLSEQMPVAVTNRYPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVH
DLVLDNIIYCPERLHLNAQWHKLLPPLGPEQNQGYWRLTTQGMAQARPIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLK
RHRYRAEHAHLLPDGEQLDLIMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGS
EHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRSPVLPAKNEP

Sequences:

>Translated_290_residues
MRAPLLLESRDYLLSEQMPVAVTNRYPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVH
DLVLDNIIYCPERLHLNAQWHKLLPPLGPEQNQGYWRLTTQGMAQARPIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLK
RHRYRAEHAHLLPDGEQLDLIMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGS
EHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRSPVLPAKNEP
>Mature_290_residues
MRAPLLLESRDYLLSEQMPVAVTNRYPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRITCGDVFYIQAADHHSYESVH
DLVLDNIIYCPERLHLNAQWHKLLPPLGPEQNQGYWRLTTQGMAQARPIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLK
RHRYRAEHAHLLPDGEQLDLIMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGS
EHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRSPVLPAKNEP

Specific function: Activates expression of the rhaSR operon in response to L-rhamnose

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains

Homologues:

Organism=Escherichia coli, GI171474011, Length=275, Percent_Identity=53.8181818181818, Blast_Score=300, Evalue=8e-83,
Organism=Escherichia coli, GI1790339, Length=272, Percent_Identity=36.3970588235294, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1788725, Length=242, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790391, Length=70, Percent_Identity=37.1428571428571, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHAR_YERP3 (A7FN79)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402707.1
- ProteinModelPortal:   A7FN79
- SMR:   A7FN79
- STRING:   A7FN79
- GeneID:   5386852
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3753
- eggNOG:   COG2207
- HOGENOM:   HBG467453
- OMA:   FLEMHNK
- ProtClustDB:   PRK13501
- BioCyc:   YPSE349747:YPSIP31758_3753-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01533
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC; SSF51215 AraC_binding; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 33784; Mature: 33784

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPLLLESRDYLLSEQMPVAVTNRYPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRI
CCCCCEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEEECCCCEEE
TCGDVFYIQAADHHSYESVHDLVLDNIIYCPERLHLNAQWHKLLPPLGPEQNQGYWRLTT
EECCEEEEEECCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHCCCCCCCCCCCEEEEEH
QGMAQARPIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLKRHRYRAEHAHLLPDGEQLDL
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
EHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRSPVLPAKNEP
CHHHHHHHHHCCCCCCCHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRAPLLLESRDYLLSEQMPVAVTNRYPQETFVEHTHQFCEIVIVWRGNGLHVLNDHPYRI
CCCCCEECCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCEEEECCCCEEE
TCGDVFYIQAADHHSYESVHDLVLDNIIYCPERLHLNAQWHKLLPPLGPEQNQGYWRLTT
EECCEEEEEECCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHCCCCCCCCCCCEEEEEH
QGMAQARPIIQQLAQESRKTDSWSIQLTEVLLLQLAIVLKRHRYRAEHAHLLPDGEQLDL
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
IMSALQQSLGAYFDMADFCHKNQLVERSLKQLFRQQTGMSISHYLRQIRLCHAKCLLRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
EHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQRFIRSPVLPAKNEP
CHHHHHHHHHCCCCCCCHHHHEEECCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA