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The map label for this gene is gntR [H]

Identifier: 153950210

GI number: 153950210

Start: 4528516

End: 4529511

Strand: Reverse

Name: gntR [H]

Synonym: YpsIP31758_4022

Alternate gene names: 153950210

Gene position: 4529511-4528516 (Counterclockwise)

Preceding gene: 153947634

Following gene: 153949302

Centisome position: 95.9

GC content: 52.11

Gene sequence:

>996_bases
ATGAAGAAAAAAAGGCCAGTGCTACAAGATGTCGCCGATATGGTGGGAGTCACTAAAATGACTGTCAGCCGTTATTTGCG
GAATCCAGAACAGGTTTCTGCTGTTTTACAGGAAAAAATCGCGCTGGCGTTGGACGAATTGGGCTATATCCCCAACCGCG
CTCCCGATATTCTCTCTAATGCCACCAGCCATGCCATTGGTGTGCTGCTGCCGTCGTTAACTAATCAGGTTTTTGCTGAG
GTTTTGCGGGGGATAGAGAGTGTGACGGATGCGCACGGTTACCAGACGATGCTGGCTCACTACGGCTATCAGAAAGAGCG
CGAAGAGCAGCGGCTGACGTCGCTTCTCTCCTACAATATTGATGGCCTCATCCTCTCTGAACGCCACCATACCGCGCGGA
CCCTGAAAATGATTGAGGTCGCGGGTATCCCTGTTATTGAGCTAATGGATTGTACTTCGCCTTGCCTTGATCTGGCTGTG
GGGTTTAATAACTTTGAGGCCGCCCGGCAGATGACACAGCAAATTATCGCTAAAGGCCATCGCTATGTGGTGTATTTTGG
CGCTCGCCAAGATGAGCGCACGGTGATCAAGCAGCAGGGCTATGAGCAAGCCATGCGCGAATCCGGTCTGGTACCGATGA
GCGTGATGACCAGCCGTTCATCGTCATATTCCGCTGGCGCTGAACTGCTACGTGAAGCGCAGGTCAGTTATCCACAAATC
GACAGTATTTTCTGTACCAATGATGATTTAGCCATTGGTGCCGTATTTGAATGTCAGCGTCAGGGGCTATCCATCCCCCA
TGACATGGCTATTGCCGGTTTCCATGGCCATGATATCGGCCAGTCGATGGTACCGAAACTGGCCAGCGTACTGACACCGA
GGGAAAGAATGGGGCAAATCGGTGCCGAGCGTTTATTGGCCAGGTTGCGCGGAGAAGTGGTAACACCCCAAATGGTGGAT
GTCGGCTTTACCATCCTCCCCGGTGGCAGTATATAA

Upstream 100 bases:

>100_bases
TACCCCCGGTTTACGTTAACTAAAAAGGGTATGCACATCGCGCTATACCCTTTTCTTTGCTAGAATTGCCTCCCGTTCAT
CCAGCCTCAGTTCATTGATA

Downstream 100 bases:

>100_bases
AGAATATAGTAATCATTTATATAGTAACTATTTATATAACAACCATTTATAGCGCCGTTGGCTAAATAACCAGAGACAGC
AACAAACAGCCGATCAACCC

Product: LacI family sugar-binding transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKKKRPVLQDVADMVGVTKMTVSRYLRNPEQVSAVLQEKIALALDELGYIPNRAPDILSNATSHAIGVLLPSLTNQVFAE
VLRGIESVTDAHGYQTMLAHYGYQKEREEQRLTSLLSYNIDGLILSERHHTARTLKMIEVAGIPVIELMDCTSPCLDLAV
GFNNFEAARQMTQQIIAKGHRYVVYFGARQDERTVIKQQGYEQAMRESGLVPMSVMTSRSSSYSAGAELLREAQVSYPQI
DSIFCTNDDLAIGAVFECQRQGLSIPHDMAIAGFHGHDIGQSMVPKLASVLTPRERMGQIGAERLLARLRGEVVTPQMVD
VGFTILPGGSI

Sequences:

>Translated_331_residues
MKKKRPVLQDVADMVGVTKMTVSRYLRNPEQVSAVLQEKIALALDELGYIPNRAPDILSNATSHAIGVLLPSLTNQVFAE
VLRGIESVTDAHGYQTMLAHYGYQKEREEQRLTSLLSYNIDGLILSERHHTARTLKMIEVAGIPVIELMDCTSPCLDLAV
GFNNFEAARQMTQQIIAKGHRYVVYFGARQDERTVIKQQGYEQAMRESGLVPMSVMTSRSSSYSAGAELLREAQVSYPQI
DSIFCTNDDLAIGAVFECQRQGLSIPHDMAIAGFHGHDIGQSMVPKLASVLTPRERMGQIGAERLLARLRGEVVTPQMVD
VGFTILPGGSI
>Mature_331_residues
MKKKRPVLQDVADMVGVTKMTVSRYLRNPEQVSAVLQEKIALALDELGYIPNRAPDILSNATSHAIGVLLPSLTNQVFAE
VLRGIESVTDAHGYQTMLAHYGYQKEREEQRLTSLLSYNIDGLILSERHHTARTLKMIEVAGIPVIELMDCTSPCLDLAV
GFNNFEAARQMTQQIIAKGHRYVVYFGARQDERTVIKQQGYEQAMRESGLVPMSVMTSRSSSYSAGAELLREAQVSYPQI
DSIFCTNDDLAIGAVFECQRQGLSIPHDMAIAGFHGHDIGQSMVPKLASVLTPRERMGQIGAERLLARLRGEVVTPQMVD
VGFTILPGGSI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=79.4561933534743, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=45.4819277108434, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1790369, Length=323, Percent_Identity=28.4829721362229, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=25.7575757575758, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788474, Length=315, Percent_Identity=25.0793650793651, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787906, Length=274, Percent_Identity=27.007299270073, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787948, Length=319, Percent_Identity=24.4514106583072, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1789068, Length=318, Percent_Identity=25.4716981132075, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786540, Length=319, Percent_Identity=24.7648902821317, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=24.0963855421687, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=23.8907849829352, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790689, Length=333, Percent_Identity=21.3213213213213, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36519; Mature: 36519

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKRPVLQDVADMVGVTKMTVSRYLRNPEQVSAVLQEKIALALDELGYIPNRAPDILSN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSHAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYGYQKEREEQRLTSLLSYNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
DGLILSERHHTARTLKMIEVAGIPVIELMDCTSPCLDLAVGFNNFEAARQMTQQIIAKGH
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
RYVVYFGARQDERTVIKQQGYEQAMRESGLVPMSVMTSRSSSYSAGAELLREAQVSYPQI
EEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCC
DSIFCTNDDLAIGAVFECQRQGLSIPHDMAIAGFHGHDIGQSMVPKLASVLTPRERMGQI
CEEEECCCCCEEHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHH
GAERLLARLRGEVVTPQMVDVGFTILPGGSI
HHHHHHHHHCCCCCCCHHHHCCEEECCCCCC
>Mature Secondary Structure
MKKKRPVLQDVADMVGVTKMTVSRYLRNPEQVSAVLQEKIALALDELGYIPNRAPDILSN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ATSHAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYGYQKEREEQRLTSLLSYNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
DGLILSERHHTARTLKMIEVAGIPVIELMDCTSPCLDLAVGFNNFEAARQMTQQIIAKGH
CEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
RYVVYFGARQDERTVIKQQGYEQAMRESGLVPMSVMTSRSSSYSAGAELLREAQVSYPQI
EEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCC
DSIFCTNDDLAIGAVFECQRQGLSIPHDMAIAGFHGHDIGQSMVPKLASVLTPRERMGQI
CEEEECCCCCEEHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHH
GAERLLARLRGEVVTPQMVDVGFTILPGGSI
HHHHHHHHHCCCCCCCHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]