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The map label for this gene is gntK [H]

Identifier: 153949302

GI number: 153949302

Start: 4526418

End: 4526921

Strand: Reverse

Name: gntK [H]

Synonym: YpsIP31758_4020

Alternate gene names: 153949302

Gene position: 4526921-4526418 (Counterclockwise)

Preceding gene: 153950210

Following gene: 153947919

Centisome position: 95.84

GC content: 50.79

Gene sequence:

>504_bases
ATGGCGGGACAGAGCATTATCGTGATGGGCGTATCGGGTAGTGGTAAAACCACAGTCGGGGAGGCTGTCGCGCGCCAGAT
TCATGCCAAATTTATTGATGGTGATGATTTACACCCCCGCGCCAATATTCAGAAAATGGGGAGTGGGCAACCGCTTAATG
ACGCGGACCGTATGCCATGGTTAGAGCGCCTAAGCGATGCGGCTTACAGCCTGAGCCATAAAAATGAAACGGGCATTATT
GTTTGTTCTGCGCTGAAACGTTGTTACCGCGATCGCTTGCGCGAGGGCAATCAGGGCATGGTATTTTTATATCTGAAGGG
CAATTTTCACGTCATCATGGCGCGGCTGCAAGCACGTTCCGGCCATTTTATGCCAAGCGATTTATTAAAAAGCCAATTTG
ACGCCTTGGAAGAACCCGGCCCGGATGAGCCTGATGTGATTTGTGTGGATATTGATACTGATATTGATGAGGTTGTCCGG
CGATGCGTGGGGGCGTTGGCTTAG

Upstream 100 bases:

>100_bases
CACATCTCCATTTGTTACCGGTATCATGATACCGGTAACATGATAAAATACGGAACTATAGGCACCAGTAGAATTTCCAT
TCTGAGATAGAGATCAACAT

Downstream 100 bases:

>100_bases
TGAGTTGATTTGGTGATCTGGAGCTGGTTCGCGTCATCGGATTTTGCCAGCAGTCTGATAAAGTAATTTTATATCTATAC
GGGGTAAACTCAGGGGCTTT

Product: thermoresistant gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MAGQSIIVMGVSGSGKTTVGEAVARQIHAKFIDGDDLHPRANIQKMGSGQPLNDADRMPWLERLSDAAYSLSHKNETGII
VCSALKRCYRDRLREGNQGMVFLYLKGNFHVIMARLQARSGHFMPSDLLKSQFDALEEPGPDEPDVICVDIDTDIDEVVR
RCVGALA

Sequences:

>Translated_167_residues
MAGQSIIVMGVSGSGKTTVGEAVARQIHAKFIDGDDLHPRANIQKMGSGQPLNDADRMPWLERLSDAAYSLSHKNETGII
VCSALKRCYRDRLREGNQGMVFLYLKGNFHVIMARLQARSGHFMPSDLLKSQFDALEEPGPDEPDVICVDIDTDIDEVVR
RCVGALA
>Mature_166_residues
AGQSIIVMGVSGSGKTTVGEAVARQIHAKFIDGDDLHPRANIQKMGSGQPLNDADRMPWLERLSDAAYSLSHKNETGIIV
CSALKRCYRDRLREGNQGMVFLYLKGNFHVIMARLQARSGHFMPSDLLKSQFDALEEPGPDEPDVICVDIDTDIDEVVRR
CVGALA

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=173, Percent_Identity=41.6184971098266, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI1790719, Length=166, Percent_Identity=60.2409638554217, Blast_Score=211, Evalue=2e-56,
Organism=Escherichia coli, GI87082265, Length=157, Percent_Identity=56.687898089172, Blast_Score=198, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25146487, Length=170, Percent_Identity=42.9411764705882, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320454, Length=157, Percent_Identity=38.2165605095541, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18356; Mature: 18225

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQSIIVMGVSGSGKTTVGEAVARQIHAKFIDGDDLHPRANIQKMGSGQPLNDADRMPW
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCHH
LERLSDAAYSLSHKNETGIIVCSALKRCYRDRLREGNQGMVFLYLKGNFHVIMARLQARS
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEHHHCC
GHFMPSDLLKSQFDALEEPGPDEPDVICVDIDTDIDEVVRRCVGALA
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AGQSIIVMGVSGSGKTTVGEAVARQIHAKFIDGDDLHPRANIQKMGSGQPLNDADRMPW
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCHH
LERLSDAAYSLSHKNETGIIVCSALKRCYRDRLREGNQGMVFLYLKGNFHVIMARLQARS
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEHHHCC
GHFMPSDLLKSQFDALEEPGPDEPDVICVDIDTDIDEVVRRCVGALA
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]