Click here to switch to the map view.

The map label for this gene is lsrD

Identifier: 153950060

GI number: 153950060

Start: 3977455

End: 3978456

Strand: Direct

Name: lsrD

Synonym: YpsIP31758_3523

Alternate gene names: 153950060

Gene position: 3977455-3978456 (Clockwise)

Preceding gene: 153950553

Following gene: 153948942

Centisome position: 84.21

GC content: 55.09

Gene sequence:

>1002_bases
ATGAATCTCTACCGACGTTATGGATGGGAACTGACTCTGGCGGCGCTGCTGGTGCTGGAAATCCTGCTATTTGGTTTATC
GAATTCGCGCATGTTGGATATCAATGTGCTGCTGTTCAGTACCAGTGATTTTATCTGCATCGGGATCGTGGCGCTGCCAT
TGACCATGGTGATTGTCAGTGGCGGCATCGATATTTCATTCGGTTCGACTATCGGGTTGTGCGCCATATTTCTGGGCATT
GTGTTTCAGGCGGGCGTGCCGATGAGTGTGGCTATCCCACTGACAGTGCTCATCGGCGCACTGTGTGGGTTAATTAATGC
CGGATTGATCCTCTATACCGGCGTCAACCCCTTGGTCATCACGCTCGGCACCCTGTATCTGTTCGGTGGCAGTGCCCTGC
TGTTATCCGGCCTCTCCGGTGCGACAGGCTATGAAGGGATTGGCGGTTTCCCGGCCGCTTTTACTGATTTCGCCAACCAA
ACCCTCTTCGGGCTGCCAATCCCCCTGGTGATATTTATGCTGTGTGTGCTGCTGTTCTGGCTGCTGATGCACCGTACTCA
CAGTGGCCGCCACGTGTTCCTGATTGGGCAAAGCAGCCGAGTCGCCCGTTACAGCGCCCTGCCCATCGCCCGCACCTTAT
GCATGCTGTATGCCATGACCGGGGTGGCCTCAGCGATTGCCGCCATTCTGCTGGTGTCTTATTTCGGCTCCGCACGCTCT
GATTTAGGTGCCTCATTCCTGATGCCGGCGATCACCGCCGTGGTATTGGGAGGGGCCAATATTTACGGGGGATCCGGCTC
CATTCTTGGAACTGCCTTGGCGGTATTACTGGTCGGGTACCTGCAACAAGGTCTGCAAATGATTGGTACGCCAAACCAAA
TTTCCAGTGCGCTGTCTGGGGCATTGCTGATTCTGGTGGTGGTTGGGCGATCGATCAGTCTGCACAGGCATTTGATTTAT
GAATGGCTACAACGTCGTCGCAGTCGAAAGGCCTCGGCGTGA

Upstream 100 bases:

>100_bases
AGAAATATGCCCGCTTCACTGCCCGAGCCATTATTAGTGATAAAAAAACAACCGTTAGCGATAACACTCCAGCGGCTAGC
AATAAAAAGAAGGCGGCATT

Downstream 100 bases:

>100_bases
TACCTAAACCCAACACCCAACAAGACAGTGATTCGGAGATAGCAATGAGAACACAAAGATTAAAAAAATTAGCACTGGTT
TGCGCTCTTGGATTTGCCTG

Product: autoinducer AI-2 ABC transporter permease LsrD

Products: NA

Alternate protein names: AI-2 import system permease protein lsrD

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLIGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAIAAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA

Sequences:

>Translated_333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLIGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAIAAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA
>Mature_333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLIGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAIAAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1787794, Length=325, Percent_Identity=80.6153846153846, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1790524, Length=251, Percent_Identity=28.2868525896414, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693152, Length=241, Percent_Identity=29.045643153527, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790191, Length=313, Percent_Identity=29.3929712460064, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788896, Length=312, Percent_Identity=26.6025641025641, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788471, Length=221, Percent_Identity=31.2217194570136, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787793, Length=311, Percent_Identity=29.903536977492, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082395, Length=313, Percent_Identity=26.8370607028754, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789992, Length=137, Percent_Identity=30.6569343065693, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693214, Length=274, Percent_Identity=26.6423357664234, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSRD_YERP3 (A7FMJ9)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402477.1
- STRING:   A7FMJ9
- GeneID:   5384330
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3523
- NMPDR:   fig|349747.3.peg.3191
- eggNOG:   COG1172
- HOGENOM:   HBG663180
- OMA:   LNWESAL
- ProtClustDB:   PRK15038
- BioCyc:   YPSE349747:YPSIP31758_3523-MONOMER
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 35133; Mature: 35133

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22b47f4c)-; HASH(0x22a9a928)-; HASH(0x22ff5158)-; HASH(0x23143750)-; HASH(0x232720c0)-; HASH(0x22b5270c)-; HASH(0x22175090)-; HASH(0x23353c18)-; HASH(0x22fb1d3c)-; HASH(0x2308c7bc)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVS
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
GGIDISFGSTIGLCAIFLGIVFQAGVPMSVAIPLTVLIGALCGLINAGLILYTGVNPLVI
CCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHH
TLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQTLFGLPIPLVIFMLCVLLFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAIAAILLVSYFGSARS
HHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSG
HCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALLILVVVGRSISLHRHLIYEWLQRRRSRKASA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVS
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
GGIDISFGSTIGLCAIFLGIVFQAGVPMSVAIPLTVLIGALCGLINAGLILYTGVNPLVI
CCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHH
TLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQTLFGLPIPLVIFMLCVLLFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAIAAILLVSYFGSARS
HHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSG
HCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALLILVVVGRSISLHRHLIYEWLQRRRSRKASA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA