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The map label for this gene is hpmA [H]

Identifier: 153949762

GI number: 153949762

Start: 4595913

End: 4597304

Strand: Reverse

Name: hpmA [H]

Synonym: YpsIP31758_4077

Alternate gene names: 153949762

Gene position: 4597304-4595913 (Counterclockwise)

Preceding gene: 153949496

Following gene: 153950209

Centisome position: 97.33

GC content: 37.28

Gene sequence:

>1392_bases
ATGAAATTGACATATATTAAAACGAAACAGGGATTGTCTATATTGCCTCTCTCTATCATATTGTCGCTCTATGGGAGTTC
GGTTGCTTATGCTGATAATATTATTGCTGATGTACAGGCTCCAATTGGACAGCAAGCGGAAGTCTCTATTATAAAAACGC
CGCCCAGTGTATGCCGAGCGCTTACCTCTTACTGTGTCGGTATGACAGAGACCGTCGTTAATATTCAAGCACCTGATGAA
AATGGTTTATCACATAACAAGTATTCTAAATTTGATGTGGTCGCTAATGGCTTATTCGATGTCACGACACTGAATAATCG
TTTAGCACAAGAGGTTGATGGTAACTCTTTTTTACAAGACAAGTTAGCAACCATTATATTAAATGAAGTCAATTCATCAC
AGGCTAGTCTATTAGATGGGAATCTCCATGTTGGTGGGCAAGATGCGCATGTCATTATTGCTAATCCAGCGGGTATTAAT
TGTCGAGGGTGCTCCTTTACCAATACCTCTCATGTGACATTGACTACCGGGGCACCATCGTTTAGTAACAATAAGCTAAA
TAATTTCATTGTTGAGCAGGGTAATATTAATATTGAAAAAGATCCCTCTTACTATATGAAAAGTGGCTTGCGAAATAAAA
GTATGGATACGACTTACCTTGATTTATTTGCGGAAAAAATCACTGTCAATGGTGATATCAATGCGGACGATGTTTATATT
GTCACGGGAAAAAATAAAGTAGGTTTCTCTTTGCCTGGGCAACCATTGCACGTGTCGCGTTTAGACAATGAAAATACACC
AGTACCAGATACAGTTAGTTTGGATGTCAGTGAAATTGGGGGAATGTACGCCAATAAAATTCGTATCTATACAACCGATA
GCACGATTAAAAATAAGGGGGCAATACGCGCCAACGATACACTAAGCCTCAGTTCTGCAGCCAATATAGATAACAGTAAT
GGGAATATATCAGGTAAAATGGTGTTACTGAGCAGCGAGGGTGTTATAAATAACTCTGGTGGCACAATATTAAATAATGG
TGAGTATGATTTATTACCTTCTCAAGGTATTAAAATAACATCTCGTGGGTTAAATAATGAAGGTGGAAAAATAGAGTATA
AAAATGGTAGCGTTGAAATAGCAACAGTTAACACCATCAAAAATGGTAAAGGTACAATTAAAGCAACATCAACGCAAGGG
CGGGTAAAAATGAACCTTCACAGTAATCATCTTAATAATACTGGAGGGAGTGTCATTTCTTCAGGAAAAGTAGAGGGTAA
AGTTAATAATATACGAAACAATAGAGGGTCCATTATAGGTTTAGGGGGAGTGGATTTGAATGAAACTGTTTTAATTAATA
GTACCGGTAAAATAATTTCTGGTTTTAATTGA

Upstream 100 bases:

>100_bases
TTGTTGACTTTGTTTTATGAAAAACCGGTAATGATGTCAGTTTTAGACGGTGTTATTCACAACATAACAAACACATTAAT
TATTTAATAAGGGGAATGAT

Downstream 100 bases:

>100_bases
TTTTTTAAATGACAGATAAATTATCTTTTAAAAAGTTAGTCACTTTTCGTGGCTGACTTTTATTGACGTGTCTTAATCAT
ATTCTTATTGAAATGGAGTT

Product: hemagglutinin/hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIADVQAPIGQQAEVSIIKTPPSVCRALTSYCVGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVDGNSFLQDKLATIILNEVNSSQASLLDGNLHVGGQDAHVIIANPAGIN
CRGCSFTNTSHVTLTTGAPSFSNNKLNNFIVEQGNINIEKDPSYYMKSGLRNKSMDTTYLDLFAEKITVNGDINADDVYI
VTGKNKVGFSLPGQPLHVSRLDNENTPVPDTVSLDVSEIGGMYANKIRIYTTDSTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVKMNLHSNHLNNTGGSVISSGKVEGKVNNIRNNRGSIIGLGGVDLNETVLINSTGKIISGFN

Sequences:

>Translated_463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIADVQAPIGQQAEVSIIKTPPSVCRALTSYCVGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVDGNSFLQDKLATIILNEVNSSQASLLDGNLHVGGQDAHVIIANPAGIN
CRGCSFTNTSHVTLTTGAPSFSNNKLNNFIVEQGNINIEKDPSYYMKSGLRNKSMDTTYLDLFAEKITVNGDINADDVYI
VTGKNKVGFSLPGQPLHVSRLDNENTPVPDTVSLDVSEIGGMYANKIRIYTTDSTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVKMNLHSNHLNNTGGSVISSGKVEGKVNNIRNNRGSIIGLGGVDLNETVLINSTGKIISGFN
>Mature_463_residues
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIADVQAPIGQQAEVSIIKTPPSVCRALTSYCVGMTETVVNIQAPDE
NGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVDGNSFLQDKLATIILNEVNSSQASLLDGNLHVGGQDAHVIIANPAGIN
CRGCSFTNTSHVTLTTGAPSFSNNKLNNFIVEQGNINIEKDPSYYMKSGLRNKSMDTTYLDLFAEKITVNGDINADDVYI
VTGKNKVGFSLPGQPLHVSRLDNENTPVPDTVSLDVSEIGGMYANKIRIYTTDSTIKNKGAIRANDTLSLSSAANIDNSN
GNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKITSRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQG
RVKMNLHSNHLNNTGGSVISSGKVEGKVNNIRNNRGSIIGLGGVDLNETVLINSTGKIISGFN

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. HpmA requires hpmB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 49216; Mature: 49216

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIADVQAPIGQQAEVSIIKTPPSVCRA
CEEEEEECCCCCEEEHHHHHHHHHCCCEEHHHHHHEECCCCCCCCCEEEEEECCHHHHHH
LTSYCVGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVDGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHCCCCHHHHH
KLATIILNEVNSSQASLLDGNLHVGGQDAHVIIANPAGINCRGCSFTNTSHVTLTTGAPS
HHHEEEEECCCCCCCEEECCCEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCC
FSNNKLNNFIVEQGNINIEKDPSYYMKSGLRNKSMDTTYLDLFAEKITVNGDINADDVYI
CCCCCCCEEEEECCCEEEECCCCHHHHCCCCCCCCCHHHHEEEEEEEEECCCCCCCCEEE
VTGKNKVGFSLPGQPLHVSRLDNENTPVPDTVSLDVSEIGGMYANKIRIYTTDSTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHCCEEECEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCCEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVKMNLHSNHLNNTGGSVIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKVEGKVNNIRNNRGSIIGLGGVDLNETVLINSTGKIISGFN
CCCCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC
>Mature Secondary Structure
MKLTYIKTKQGLSILPLSIILSLYGSSVAYADNIIADVQAPIGQQAEVSIIKTPPSVCRA
CEEEEEECCCCCEEEHHHHHHHHHCCCEEHHHHHHEECCCCCCCCCEEEEEECCHHHHHH
LTSYCVGMTETVVNIQAPDENGLSHNKYSKFDVVANGLFDVTTLNNRLAQEVDGNSFLQD
HHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHHHHCCCCHHHHH
KLATIILNEVNSSQASLLDGNLHVGGQDAHVIIANPAGINCRGCSFTNTSHVTLTTGAPS
HHHEEEEECCCCCCCEEECCCEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCC
FSNNKLNNFIVEQGNINIEKDPSYYMKSGLRNKSMDTTYLDLFAEKITVNGDINADDVYI
CCCCCCCEEEEECCCEEEECCCCHHHHCCCCCCCCCHHHHEEEEEEEEECCCCCCCCEEE
VTGKNKVGFSLPGQPLHVSRLDNENTPVPDTVSLDVSEIGGMYANKIRIYTTDSTIKNKG
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHCCEEECEEEEEECCCCCCCCC
AIRANDTLSLSSAANIDNSNGNISGKMVLLSSEGVINNSGGTILNNGEYDLLPSQGIKIT
CEEECCCEEECCCCCCCCCCCCEEEEEEEEECCCEEECCCCEEEECCCEEECCCCCCEEE
SRGLNNEGGKIEYKNGSVEIATVNTIKNGKGTIKATSTQGRVKMNLHSNHLNNTGGSVIS
ECCCCCCCCEEEEECCCEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCCCEEE
SGKVEGKVNNIRNNRGSIIGLGGVDLNETVLINSTGKIISGFN
CCCCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]