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The map label for this gene is yicI [C]

Identifier: 153949651

GI number: 153949651

Start: 1107442

End: 1109817

Strand: Reverse

Name: yicI [C]

Synonym: YpsIP31758_0924

Alternate gene names: 153949651

Gene position: 1109817-1107442 (Counterclockwise)

Preceding gene: 153948424

Following gene: 153949216

Centisome position: 23.5

GC content: 50.72

Gene sequence:

>2376_bases
ATGAAAACATTAAAAAACTGGCTGTTAATCAATGAGTATCCCGATCACCTTGAACTGCGGGTCGATGACCGTCATATCTT
TTGTCTGTATGTATTAGAACCAAACTTATGCAGGGTGCTGATTAAACGCGAGGGTGAACTGGCACTGAGCCGCACCTGGA
GTATTGCCCCGCAAGGTGATGTGCCATGGTCAGGCCGCGATCGCCTGAGTCTGGAAGGCTTCTCTCTCCCCGGTTATCAA
TTGGAGAAACATGAACAGCAACTGGTCGTCACGACGGAGTGCCTTCGGGTCACCATCCATCAACCACTGCATCTGACATG
GGAATATAAAAACCCGCCTGGTGAGTGGCTACCGCTGGCCGCAGACCGGCCAACCAGCGCCTATCTACTCAGCCCTCAGG
GAGAAGCGATTGCTCACTATCAGCGCCGTTATCCCAATGAACAATATTACGGATTGGGCGAAAAAGCCGGTGACCTGAAC
CGCGCAGGTCGTCGCTTTGAAATGCGTAATCTGGATGCGATGGGCTATAACGCCGCCAGCACGGACCCGCTCTACAAACA
TATTCCGTTTACTATCACCCGCCGTGATGATGTCAGTTTTGGCCTTTTTTATGACAATCTGAGTAGCTGTTGGCTGGATT
TAGGCAATGAGATCGATAACTACCATCTGGCCTATCGCCGTTATCAGGCCGAAGCGGGTGACCTTGATTACTATCTGTTC
CTCGGCCCGAAAGTTTTGGATGTCACCAAAGCGTTTGTCCGCCTGACCGGTAAAACCCAATTTGGCCCTAAATGGAGCCT
GGGTTACAGCGGTTCAACCATGCATTACACCGATGCCCCTGATGCTCAGGTACAACTGCAAAAGTTCATTGCATTGTGTC
AGCAGCATGACATCCCTTGCGATTCGTTCCAGCTCTCTTCCGGCTACACCTCCATCAAAAACAAGCGTTATGTCTTTAAC
TGGAATTACGACAAAGTGCCGCAACCGAAAGTCATGAGCCAGACGTTCCTACAAGCAGGTATCAAATTAGCCGCCAATAT
AAAACCGTGTTTATTGCAAGATCACCCACAGTATCAACAGGCTGCGGAGCGGGGGCTTTTCATTCGCGACAGCGAAACTG
ATTTACCTGAACGCTCTACATTTTGGGATGATGAAGGCTCCCACCTTGATTTCACCAATCCAGACACCGTGATCTGGTGG
CAAGAGAACGTCACTAAACAGCTCTTGGAGATGGGGATCGGTTCTACCTGGAATGATAATAACGAATATGAAGTGTGGGA
TGGTGAAGCCCGCTGTAATGGCTTCGGTAAATCTATCGCCATCAAACATATCAGACCGGTAATGCCTTTACTGATGATGC
GAGCCTCAATGGAAGCGCAGAAAGCATTCGCACCAGAAATGCGCCCATACCTGATATCCCGTTCAGGCTGTGCAGGGATG
CAGCGCTACGCTCAGACCTGGAGTGGTGATAACCGTACCAGTTGGCAAACACTGCGCTATAACATCCGAATGGGGCTGGG
GATGAGCCTGTCAGGGCTGTATAACCTGGGGCATGATGTCGGCGGTTTTTCTGGAGATAAACCGGAACCTGAGCTGTTTG
TCCGCTGGGTACAAAACGGTGTGATGCATCCACGGTTTACCATTCATTCATGGAATGATGACAATACAGTCAACGAGCCA
TGGATGTATCCAGCCGCCACGCCGATGATCCGGGATGCGATGGCGTTACGATATCGATTATTGCCCTATTTTTACACATT
GCAATGGCAGGCCAGCCATGATGATGAGCCGATGTTGCGCCCTACGTTCCTCGACCACGAACACGATAGCCTCACATTTA
AAGAGAACGATGACTTTATGCTAGGCCGTGATCTGTTGGTTGCCAGTGTGGTGGACGCTGGGCAACGGCAACGGCAGATT
TATTTACCTGATAATCAGGTCGGCTGGTATTGCTTCCACAGCGGGCAATGGTATAGCGGTGGGCAGACAATCACATTGGA
TGCACCACTAGAGCGATTACCTCTGCTGGTACGCGCGGGGGCAGCCCTGCCGCTATCCCGACGTATCGCCTTTGTTAATC
CTGAGGCTGATTGTCAGCGCGAATTGGCGCTTTATCCCACTCAAGGTGGCGGGCAATCGAGCGGGATGCTATTTGAGGAC
GATGGTGAAAGCCACCGCTGGCAACAAGGCCATGCGCTATGGCTAAGTTGGCAGGTCACCACCGATAATCACCGTATTGA
TATCACCTTTAGCCGCACCGGGAACTATCAACCGGCATGGCGTGAACTGACGATTAATTTGCCAACAAATGAAAGTCGCA
CGTTATCAATCAACGGTGTCGCAGGTAATACACTGGATTTAACCAAACTGGCCTAA

Upstream 100 bases:

>100_bases
AACTAATGTTGTTAACTAAATTGATGCGATTACCCCATCAGATGCGATTAACCCAGCAGCGGCACTGCCTGTGCTGTTGC
CAGAAAAAAGATGAGCTGTG

Downstream 100 bases:

>100_bases
CCGGCTAATGTTAAATACAAGACGGACTTCCTGATGGAAGCCCGTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAAC
AGGCAGATCGTAAAGACGCC

Product: glycosy hydrolase family protein

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGYQ
LEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPPGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLN
RAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYLF
LGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVFN
WNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVIWW
QENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAGM
QRYAQTWSGDNRTSWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNEP
WMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQI
YLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFED
DGESHRWQQGHALWLSWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA

Sequences:

>Translated_791_residues
MKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGYQ
LEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPPGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLN
RAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYLF
LGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVFN
WNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVIWW
QENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAGM
QRYAQTWSGDNRTSWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNEP
WMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQI
YLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFED
DGESHRWQQGHALWLSWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA
>Mature_791_residues
MKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGYQ
LEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPPGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLN
RAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYLF
LGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVFN
WNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVIWW
QENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAGM
QRYAQTWSGDNRTSWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNEP
WMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQI
YLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFED
DGESHRWQQGHALWLSWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI38202257, Length=658, Percent_Identity=30.0911854103343, Blast_Score=269, Evalue=7e-72,
Organism=Homo sapiens, GI88900491, Length=658, Percent_Identity=30.0911854103343, Blast_Score=269, Evalue=9e-72,
Organism=Homo sapiens, GI66346737, Length=600, Percent_Identity=29.3333333333333, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI119393895, Length=585, Percent_Identity=27.5213675213675, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI119393893, Length=585, Percent_Identity=27.5213675213675, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI119393891, Length=585, Percent_Identity=27.5213675213675, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI221316699, Length=697, Percent_Identity=24.103299856528, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI157364974, Length=659, Percent_Identity=23.6722306525038, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI310115361, Length=266, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=6e-22,
Organism=Escherichia coli, GI2367256, Length=503, Percent_Identity=25.844930417495, Blast_Score=156, Evalue=6e-39,
Organism=Escherichia coli, GI2367323, Length=380, Percent_Identity=26.8421052631579, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71991189, Length=623, Percent_Identity=29.2134831460674, Blast_Score=249, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17560798, Length=638, Percent_Identity=29.6238244514107, Blast_Score=245, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17560800, Length=638, Percent_Identity=29.6238244514107, Blast_Score=245, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI32563849, Length=579, Percent_Identity=24.6977547495682, Blast_Score=132, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71985706, Length=261, Percent_Identity=28.3524904214559, Blast_Score=101, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319706, Length=647, Percent_Identity=26.4296754250386, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24643749, Length=653, Percent_Identity=25.114854517611, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24643753, Length=653, Percent_Identity=25.114854517611, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24643751, Length=653, Percent_Identity=25.114854517611, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24643746, Length=653, Percent_Identity=25.114854517611, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21357605, Length=653, Percent_Identity=25.114854517611, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24650054, Length=372, Percent_Identity=25.5376344086022, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 90943; Mature: 90943

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGD
CCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCC
VPWSGRDRLSLEGFSLPGYQLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPPGEWLPLA
CCCCCCCCEEEECCCCCCCHHCCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCEEEEC
ADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLNRAGRRFEMRNLDAMGYNAAS
CCCCCCEEEECCCCCHHHHHHHHCCCCHHCCCCCCCCCHHHCCCEEEECCCCCCCCCCCC
TDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYLF
CCCCHHCCCEEEEECCCCEEEEEHHCHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEE
LGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPC
ECCCHHHHHHHHHEEECCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
DSFQLSSGYTSIKNKRYVFNWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQ
CCEEECCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCEEECCCCHHHH
AAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVIWWQENVTKQLLEMGIGSTWNDN
HHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHCCCCCCCCC
NEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAGM
CCEEEECCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
QRYAQTWSGDNRTSWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNG
HHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
VMHPRFTIHSWNDDNTVNEPWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLR
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCC
PTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQIYLPDNQVGWYCFHSGQWYSG
CEECCCCCCCEEEECCCCEEECHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCEEECC
GQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFED
CEEEEECCCHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEC
DGESHRWQQGHALWLSWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGV
CCCCCCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECC
AGNTLDLTKLA
CCCEEEHEECC
>Mature Secondary Structure
MKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGD
CCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCC
VPWSGRDRLSLEGFSLPGYQLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPPGEWLPLA
CCCCCCCCEEEECCCCCCCHHCCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCEEEEC
ADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLNRAGRRFEMRNLDAMGYNAAS
CCCCCCEEEECCCCCHHHHHHHHCCCCHHCCCCCCCCCHHHCCCEEEECCCCCCCCCCCC
TDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYLF
CCCCHHCCCEEEEECCCCEEEEEHHCHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEE
LGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPC
ECCCHHHHHHHHHEEECCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
DSFQLSSGYTSIKNKRYVFNWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQ
CCEEECCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCEEECCCCHHHH
AAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVIWWQENVTKQLLEMGIGSTWNDN
HHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCHHHHHHHHHCCCCCCCCC
NEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAGM
CCEEEECCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
QRYAQTWSGDNRTSWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNG
HHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
VMHPRFTIHSWNDDNTVNEPWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLR
CCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCC
PTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQIYLPDNQVGWYCFHSGQWYSG
CEECCCCCCCEEEECCCCEEECHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCEEECC
GQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFED
CEEEEECCCHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEC
DGESHRWQQGHALWLSWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGV
CCCCCCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECC
AGNTLDLTKLA
CCCEEEHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]