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The map label for this gene is tus

Identifier: 153948971

GI number: 153948971

Start: 2168751

End: 2169686

Strand: Direct

Name: tus

Synonym: YpsIP31758_1872

Alternate gene names: 153948971

Gene position: 2168751-2169686 (Clockwise)

Preceding gene: 153949397

Following gene: 153947728

Centisome position: 45.92

GC content: 43.8

Gene sequence:

>936_bases
ATGAACAAGTATGATTTGATAGAACGAATGAATACTCGCTTTGCTGAGTTAGAAGTAACACTTCATCAACTCCACCAGCA
ATTGGACGATTTACCTCTAATTGCGGCCAGAGTATTTTCTCTCCCTGAAATAGAAAAAGGCACTGAGCATCAACCCATTG
AGCAAATTACCGTCAATATAACCGAGGGTGAACACGCCAAAAAGTTGGGGTTACAACATTTCCAACGATTATTTCTTCAT
CACCAAGGGCAGCATGTTAGCAGTAAAGCAGCACTACGCTTACCTGGCGTGCTCTGCTTCTCCGTGACAGACAAAGAACT
CATTGAATGCCAAGATATAATAAAAAAAACCAATCAGTTAAAAGCTGAGTTAGAACATATTATTACTGTGGAATCAGGCT
TACCCAGCGAACAACGCTTTGAATTTGTTCACACACACTTACATGGCCTGATAACCCTGAATACCTACCGCACCATTACC
CCATTAATCAACCCCAGTTCAGTGCGCTTTGGCTGGGCCAACAAACACATTATTAAAAATGTGACTCGCGAAGATATATT
GCTACAGCTAGAAAAAAGCCTGAATGCTGGCCGAGCTGTTCCTCCATTTACGCGTGAGCAATGGAGGGAACTGATTAGCT
TGGAAATAAATGATGTGCAGCGTTTGCCAGAAAAGACACGGCTGAAAATTAAAAGGCCCGTAAAAGTGCAGCCCATCGCA
AGAGTATGGTATCAAGAACAACAAAAACAGGTACAACACCCCTGCCCCATGCCTCTGATTGCGTTCTGTCAGCGTCAGTC
AGGGGCCGAGCTACCGAAATTAGGCGAGTTGACCGATTATGATGTGAAGCATATCAAGCATAAATATAAGCCAGATGCGA
AACCGCTACGTTTGCTGGTACCGCGCTTGCATCTTTATGTCGAACTGGAACCGTAA

Upstream 100 bases:

>100_bases
TCTTTTGAATCTAATGACATTTATGTATCTACATGTGGCTATTTTTAGGAGAACAAGATAATGTATGTTGTAACTAAATC
CGCCTTATTTAGAAAAGAAT

Downstream 100 bases:

>100_bases
AGAATACCATTTATTGCGGCTTAGCCACTGTGAAAACGCCGGTAATCCACCCCGGCGTTAATATAACAATGTTTATCCGC
TATTTCTTCATACTGCCGAC

Product: DNA replication terminus site-binding protein

Products: NA

Alternate protein names: Ter-binding protein

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAKKLGLQHFQRLFLH
HQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTIT
PLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIA
RVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYVELEP

Sequences:

>Translated_311_residues
MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAKKLGLQHFQRLFLH
HQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTIT
PLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIA
RVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYVELEP
>Mature_311_residues
MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAKKLGLQHFQRLFLH
HQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTIT
PLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIA
RVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYVELEP

Specific function: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tus family

Homologues:

Organism=Escherichia coli, GI1787895, Length=307, Percent_Identity=53.7459283387622, Blast_Score=346, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUS_YERP3 (A7FHW9)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400847.1
- ProteinModelPortal:   A7FHW9
- SMR:   A7FHW9
- STRING:   A7FHW9
- GeneID:   5388239
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1872
- NMPDR:   fig|349747.3.peg.664
- eggNOG:   NOG04361
- HOGENOM:   HBG416199
- OMA:   QVQYACP
- ProtClustDB:   PRK02951
- BioCyc:   YPSE349747:YPSIP31758_1872-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00483
- InterPro:   IPR008865
- Gene3D:   G3DSA:3.50.14.10
- TIGRFAMs:   TIGR02648

Pfam domain/function: PF05472 Ter; SSF56596 Rep_term_tus

EC number: NA

Molecular weight: Translated: 36174; Mature: 36174

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
TEGEHAKKLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
KAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSSVRFGWANKHIIKN
HHHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCEECCCCCCCCEEECCCCHHHHHH
VTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHCEEECCCCCCCHHH
RVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLV
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHC
PRLHLYVELEP
CEEEEEEEECC
>Mature Secondary Structure
MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
TEGEHAKKLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
KAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSSVRFGWANKHIIKN
HHHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCEECCCCCCCCEEECCCCHHHHHH
VTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIA
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHCEEECCCCCCCHHH
RVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLV
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHC
PRLHLYVELEP
CEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA